Cullen, US
Aaron Cullen, Mililani, HI US
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20140088304 | METHODS AND INTERMEDIATES FOR PREPARING PHARMACEUTICAL AGENTS - The invention provides methods and intermediates that are useful for preparing a compound of formula I: | 03-27-2014 |
Aaron J. Cullen, Dublin, CA US
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20140364602 | METHODS AND INTERMEDIATES FOR PREPARING PHARMACEUTICAL AGENTS - Methods and intermediates useful for preparing a compound of formula I: | 12-11-2014 |
Aidan Cullen, Sunnyvale, CA US
Patent application number | Description | Published |
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20080288897 | Method Of Enforcing A Contract For A CAD Tool - A method for enforcing a contract for a computer-aided-design (CAD) tool is provided. In this method, a first payment for the CAD tool is made in accordance with the contract. The first payment is associated with user access to the CAD tool. At this point, the CAD tool can be used, wherein the computer system running the CAD tool includes criteria for requesting at least one additional payment for the CAD tool. Each additional payment is associated with generating an output. The computer system is responsive to one or more trigger conditions corresponding to the criteria. A payment request is received when an output generated by the CAD tool satisfies a trigger condition. For example, one trigger condition adds a watermark to the output for identifying the output as having been produced by the CAD tool. | 11-20-2008 |
Andrew A. Cullen, Succasunna, NJ US
Patent application number | Description | Published |
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20080270313 | Outsourced Service Level Agreement Provisioning Management System and Method - An outsourced service level agreement (SLA) deliverable management method includes configuring SLA client and secondary SLA provider master data, procuring a secondary SLA provider provision services network, administering a secondary SLA provider human resource network, processing an SLA client provisioning requirement, processing an SLA provisioning service voucher, and processing payment of an SLA provisioning work order. This Abstract is provided to comply with rules requiring an Abstract that allows a searcher or other reader to quickly ascertain subject matter of the technical disclosure. This Abstract is submitted with the understanding that it will not be used to interpret or limit the scope or meaning of the claims. | 10-30-2008 |
20110055041 | SYSTEM AND METHOD FOR MANAGING WORKFORCE TRANSITIONS BETWEEN PUBLIC AND PRIVATE SECTOR EMPLOYMENT - A method includes configuring a labor pool, the labor pool including a plurality of human resources in a first workforce sector. In addition, the method includes configuring a plurality of business entities operating in a second workforce sector that is distinct from the first workforce sector. The configuration of a plurality of business entities includes storing job-opening information for a plurality of job openings. Further, the method includes normalizing the labor pool to a human-capital management (HCM) taxonomy. Additionally, the method includes normalizing the plurality of job openings to the HCM taxonomy. The method also includes facilitating a redeployment of at least one human resource in the normalized labor pool from the first workforce sector to the second workforce sector. The facilitating includes matching the at least one human resource to at least one job opening in the normalized plurality of job openings. | 03-03-2011 |
Anthony P. Cullen, Ringwood, NJ US
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20080276024 | Method for Stabilizing Asynchronous Interfaces - A method and computer system apparatus for asynchronous data transfer between a source and sink without the use of an asynchronous control signal. includes metastability circuits, data change detection logic, a stability window delay counter, and a mux/register pair to allow for the holding of previous stable data during the transition. While the processing logic employed specifically applies to asynchronous logic, the logic can be extended to synchronous or untimed interfaces as well. Also disclosed is a programmable means to adjust the window delay. | 11-06-2008 |
Bill Cullen, Cambridge, MA US
Patent application number | Description | Published |
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20130311603 | ON-DEMAND TETHERED GREEDY VIRTUAL APPLICATION APPLIANCE - A computer-implemented virtual applicant appliance (VAA) and method for managing migration of an application on a source computer to a virtual application within the VAA on a target computer networked to the source computer are disclosed. The VAA includes resources on the target computer, a virtual application for execution in the VAA, and network credentials for remotely connecting to the source computer and copying data resources from the source computer. A runtime intercept of the VAA compares on-demand resource requests of the virtual application to resources on the target computer and provides the requested resource to the virtual application. When the runtime intercept fails to locate the requested resource in the resources on the target computer, a tether of the VAA remotely retrieves the requested resource from the source computer using the network credentials and then copies the requested resource into the resources on the target computer. | 11-21-2013 |
Brian Cullen, Costa Mesa, CA US
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20130079936 | REMOTE ACCESS FOR WATER INFRASTRUCTURE MANAGEMENT - A system for remotely monitoring and controlling a plurality of water treatment facilities distributed over a wide area includes: a plurality of interfaces configured to receive status information from the facilities and to transmit commands to control the facilities; a database for storing the status information; and a human machine interface configured to transmit the status information to a remote terminal. | 03-28-2013 |
Bruce B. Cullen, Klamath Falls, OR US
Patent application number | Description | Published |
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20090299516 | SYSTEMS AND METHODS OF IDENTIFYING AND MANIPULATING OBJECTS - Systems and methods of identifying and manipulating objects are disclosed. One system disclosed comprises a light source adapted to emit a collimated light beam onto a contoured surface, a sensor adapted to view a profile of the contoured surface illuminated by the collimated light beam, a processor in communication with the sensor, and a controller in communication with the processor. The controller may be adapted to generate a signal based on an attribute of a predefined profile. | 12-03-2009 |
Bryan R. Cullen, Durham, NC US
Patent application number | Description | Published |
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20110118332 | VIRAL MICRORNA - The present invention relates, in general, to micro RN As and. in particular, to viral microRNAs expressed by Herpes Simplex Vims 1 (HSV-1) or Herpes Simplex Virus 2 (HSV-2), to agents that inhibit such microRNAs and to methods of treatment based on the use of such agents. | 05-19-2011 |
20120255042 | METHOD OF REGULATING GENE EXPRESSION - The present invention relates, in general, to gene expression and, in particular, to a method of inhibiting the expression of a target gene and to constructs suitable for use in such a method. | 10-04-2012 |
20130191935 | METHOD OF REGULATING GENE EXPRESSION - The present invention relates, in general, to gene expression and, in particular, to a method of inhibiting the expression of a target gene and to constructs suitable for use in such a method. | 07-25-2013 |
Camillus A. Cullen, Kenmore, WA US
Patent application number | Description | Published |
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20140054417 | OVERHEAD SPACE UTILIZATION DEVICE - One particular overhead space utilization device, adapted for installation in a hull structure, incorporates at least one berth module with first and second berth portions, first and second intermediate support members, and first and second coupling members. Each berth module has two opposing berth members with a walkway therebetween. The first and second intermediate support members each has a first end pivotably coupled to the corresponding one of the first and second berth portions, and a second end configured to be pivotably coupled to the hull structure. The first and second coupling members are configured to pivotably couple the second berth portions to the hull structure. The first and second coupling members and the second berth portions are configured to be positioned outboard of the first berth portion. | 02-27-2014 |
Christopher Cullen, Ipswich, MA US
Patent application number | Description | Published |
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20100036510 | ELECTRONIC MOTOR CONTROLLER - A control system for any type of electric motor that automatically learns the characteristics of the motor and computes a motor model for the motor. The control system uses the computed motor model to produce a closed-loop control design that achieves a particular resolution. The control system also uses the motor model to automatically construct efficient motion profiles for a variety of motion commands. The control system may also include an encoder interface device that provides highly accurate motor position information. | 02-11-2010 |
Christopher P. Cullen, Ipswich, MA US
Patent application number | Description | Published |
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20090021205 | ELECTRONIC MOTOR CONTROLLER - A control system for any type of electric motor that automatically learns the characteristics of the motor and computes a motor model for the motor. The control system uses the computed motor model to produce a closed-loop control design that achieves a particular resolution. The control system also uses the motor model to automatically construct efficient motion profiles for a variety of motion commands. The control system may also include an encoder interface device that provides highly accurate motor position information. | 01-22-2009 |
Darica Jean Ann Cullen, Pahrump, NV US
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20110284185 | THERMAL FLUID TEMPERATURE CONVERTER - A thermal fluid temperature converter uses temperature from a thermal fluid to preheat or precool incoming air prior to entering a household/workplace/building/appliance. The thermal fluid temperature converter includes a hollow housing, a filter placed inside the hollow housing, and a temperature exchanger placed inside the hollow housing. The temperature exchanger is adapted to receive a thermal fluid that circulates through the coils. The air enters the hollow housing, interchanges temperature with the thermal fluid circulating through the coils, and leaves the hollow housing as a heated air or a cooled air. | 11-24-2011 |
David H. Cullen, Rock Hill, SC US
Patent application number | Description | Published |
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20140265045 | Chute for Laser Sintering Systems - There is provided improved laser sintering systems that increase the powder density and reduce anomalies of the powder layers that are sintered, that measure the laser power within the build chamber for automatic calibration during a build process, that deposit powder into the build chamber through a chute to minimize dusting, and that scrubs the air and cools the radiant heaters with recirculated scrubbed air. The improvements enable the laser sintering systems to make parts that are of higher and more consistent quality, precision, and strength, while enabling the user of the laser sintering systems to reuse greater proportions of previously used but unsintered powder. | 09-18-2014 |
20140271326 | Powder Distribution for Laser Sintering Systems - There is provided improved laser sintering systems that increase the powder density and reduce anomalies of the powder layers that are sintered, that measure the laser power within the build chamber for automatic calibration during a build process, that deposit powder into the build chamber through a chute to minimize dusting, and that scrubs the air and cools the radiant heaters with recirculated scrubbed air. The improvements enable the laser sintering systems to make parts that are of higher and more consistent quality, precision, and strength, while enabling the user of the laser sintering systems to reuse greater proportions of previously used but unsintered powder. | 09-18-2014 |
Dennis Cullen, Glenview, IL US
Patent application number | Description | Published |
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20090039214 | Carpenter's square securing apparatus - The present invention generally relates to a securing apparatus for a carpenter's square and a method for using the same. The apparatus is especially suitable for securing at least two planar surfaces in a fixed position. More specifically, the apparatus may allow a user to secure at least two planar surfaces in a fixed position to, for example, perform work on the planar surfaces. The present invention allows a user to easily secure a clamp onto a carpenter's square. | 02-12-2009 |
D. Kacy Cullen, Philadelphia, PA US
Patent application number | Description | Published |
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20100073678 | Blast injury dosimeter - A method for detecting blast induced pressure changes includes exposing a material, a contained solution, a membrane-bound solution, or a photonic crystal material, having a first optical property, to a pressure wave having a blast level. A change in the first optical property to a second optical property of the exposed material, contained solution, membrane-bound solution, or photonic crystal material is determined, and the extent of change corresponds to the blast level. | 03-25-2010 |
Donald L. Cullen, Columbus, OH US
Patent application number | Description | Published |
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20090237761 | Direction of Optical Signals by a Movable Diffractive Optical Element - A method and apparatus particularly useful for telecommunications applications, such as switching (Add/Drop), multiplexing and demultiplexing, is disclosed. The method commences by directing a source of input optical signal(s) ( | 09-24-2009 |
Edward E. Cullen, Round Rock, TX US
Patent application number | Description | Published |
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20100114624 | SYSTEM AND METHOD FOR OPTIMIZING FINANCIAL PERFORMANCE GENERATED BY MARKETING INVESTMENTS UNDER BUDGET CONSTRAINTS - Methods, systems, and computer program products are provided for optimizing financial performance. Time series data describing the financial performance generated by corresponding marketing investments is provided to configure an econometric model. Linear coefficients of the econometric model are adjusted in accordance with the qualitative factors received as inputs from experts. The econometric model is transformed into an aggregated non-linear econometric model that includes non-linear factors that cause the financial performance to change at a varying rate as a function of the marketing investments. An allocation of the marketing investments generated by the aggregated non-linear econometric model is adjusted by applying an optimization algorithm to provide an optimized financial performance. | 05-06-2010 |
20100114648 | SYSTEM AND METHOD FOR INCORPORATING QUALITATIVE INPUTS INTO ECONOMETRIC MODELS - Methods, systems, and computer program products are provided for incorporating qualitative factors into an econometric model. Time series data describing the financial performance generated by corresponding marketing investments that are made as a function of time is provided to configure an econometric model. The econometric model includes linear coefficients that define a linear relationship between the financial performance and the corresponding marketing investments. The linear coefficients are adjusted in accordance with the qualitative factors received as inputs from experts, thereby enabling the qualitative factors to be quantified into the econometric model. | 05-06-2010 |
20100114794 | PREDICTION OF FINANCIAL PERFORMANCE FOR A GIVEN PORTFOLIO OF MARKETING INVESTMENTS - Methods, systems, and computer program products are provided for quantifying financial impact of marketing investments. Time series data describing the financial performance generated by corresponding marketing investments that are made as a function of time is provided to configure an econometric model. The econometric model, which describes a linear relationship between the financial performance and the corresponding marketing investments, is transformed into an aggregated non-linear econometric model that includes non-linear factors causing the financial performance to change at a varying rate as a function of the marketing investments. | 05-06-2010 |
Fredrick Thomas Cullen, Pahrump, NV US
Patent application number | Description | Published |
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20110284185 | THERMAL FLUID TEMPERATURE CONVERTER - A thermal fluid temperature converter uses temperature from a thermal fluid to preheat or precool incoming air prior to entering a household/workplace/building/appliance. The thermal fluid temperature converter includes a hollow housing, a filter placed inside the hollow housing, and a temperature exchanger placed inside the hollow housing. The temperature exchanger is adapted to receive a thermal fluid that circulates through the coils. The air enters the hollow housing, interchanges temperature with the thermal fluid circulating through the coils, and leaves the hollow housing as a heated air or a cooled air. | 11-24-2011 |
Gerard L. Cullen, Austin, TX US
Patent application number | Description | Published |
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20100096933 | Method and system for high-reliability power switching - The present disclosure is directed to systems and methods for high-reliability power switching. | 04-22-2010 |
20100241838 | METHOD AND SYSTEM FOR FIRMWARE UPDATES - A method for updating computing device firmware may comprise: (a) receiving a transmission of firmware update data; (b) writing the firmware update data to a firmware update data partition; and (c) writing the firmware update data to an active firmware partition. | 09-23-2010 |
20120013460 | ENVIRONMENTAL ALARMS SENT VIA SMS TEXT MESSAGING - One example embodiment includes a system for remotely conveying a deleterious condition of a controlled environment. The system includes a sensor, where the sensor is configured to produce a signal which indicates a measured value of an environmental condition in a controlled environment. The system also includes a monitoring unit. The monitoring unit is configured to receive the signal from the sensor, determine the value of the environmental condition and determine whether the value of the environmental condition exceeds predetermined boundaries. The system further includes an electronic circuit, where the electronic circuit is configured to transmit an alert message if the monitoring unit determines the value of the environmental condition exceeds the predetermined boundaries. | 01-19-2012 |
Greg Cullen, Amesbury, MA US
Patent application number | Description | Published |
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20110044874 | Oxidation Catalyst and Method for Destruction of CO, VOC and Halogenated VOC - An oxidation catalyst deposited on a substrate is described for the destruction of CO and volatile organic compounds, in particular halogenated organic compounds, from an emissions stream at temperatures from 250° C. to 450° C. The oxidation catalyst includes at least two platinum group metals, one of which is either platinum or ruthenium, supported on refractory oxides, such as a solid solution of CeO | 02-24-2011 |
20120128563 | METHOD FOR REMOVING CO, H2 AND CH4 FROM AN ANODE WASTE GAS OF A FUEL CELL AND CATALYST SYSTEM USEFUL FOR REMOVING THESE GASES - A system for removing CO, H | 05-24-2012 |
James M. Cullen, Aroda, VA US
Patent application number | Description | Published |
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20130326846 | CLIP FOR SECURING GUTTER GUARD TO GUTTER - A clip connecting the outer end of a gutter guard to the outer end of a gutter. The clip has an outwardly extending lower panel, a front panel extending upwardly from an inner end of the lower panel, the front panel merging with an intermediate panel that extends outwardly over the lower panel. The lower and intermediate panels are constructed to engage the outer gutter end to connect the clip thereto. The intermediate panel is folded inwardly at its outer end and merges with an upper panel extending inwardly over the intermediate panel. The intermediate and upper panels are constructed to receive and retain therebetween the gutter guard outer end. | 12-12-2013 |
John Cullen, Redwood City, CA US
Patent application number | Description | Published |
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20090244619 | AUTOMATIC AND TRANSPARENT DOCUMENT ARCHIVING - An automatic archiving system that makes document archiving largely transparent to the user. In one embodiment, documents scanned in or printed during the course of office equipment operation are automatically archived. For example, an office local area network (LAN) may interconnect a copier, a printer, a fax machine, and a document management workstation. Whenever, a document is copied, printed, or faxed, a document image is archived by the document management workstation without further user intervention. A single user command results in the document being copied and archived, printed and archived, Of faxed and archived. | 10-01-2009 |
John Cullen, Redwoody City, CA US
Patent application number | Description | Published |
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20120019854 | Automatic and Transparent Document Archiving - An automatic archiving system makes document archiving largely transparent to the user. In one embodiment, documents scanned in or printed during the course of office equipment operation are automatically archived. When a document is copied, printed, or faxed, a document image is archived by the document management workstation without further user intervention. A single user command results in the document being copied and archived, printed and archived, or faxed and archived. In accordance with a first aspect, an image processing device includes a receiving means for receiving a single input, a printing means, a memory device, and a communication means for communicating with said memory device. Responsive to receiving said single input requesting the printing of a document by said receiving means, said printing means prints the document and said communication means sends image data representing said document to said memory device. | 01-26-2012 |
John Cullen, Dallas, TX US
Patent application number | Description | Published |
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20140310089 | Fuel Reward and Loyalty Space System and Method - A fuel-based consumer reward and loyalty space system and method in which a consumer can earn points towards a reward card with a predetermined dollar balance to be used to purchase fuel at the gasoline brand of their choice. The merchant can set up predetermined categories, or no categories at all, in which to allow a consumer frequenting the merchant to earn loyalty points. The consumer uses a loyalty token at the register to identify themselves and earn points upon purchasing products, with the point value set by the merchant. The points earned from each purchase are added to the consumer's account, stored in a database. Points are aggregated in the consumer's account across all participating merchants. Once the consumer's points reach a predetermined amount, such as 2,550 points, the consumer is automatically awarded a reward card with a predetermined reward amount added to the card. If the consumer already has a reward card, the predetermined amount is automatically added to the existing reward card in real-time, without any action on the part of the consumer. | 10-16-2014 |
John Cullen, Mequon, WI US
Patent application number | Description | Published |
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20090126673 | THERMALLY INSULATING ELEMENT FOR AN ENGINE VALVE ASSEMBLY - A cylinder head assembly for an internal combustion engine including a cylinder head at least partially defining a flow path through the engine, including an intake port, an exhaust port, and a combustion chamber disposed between the intake post and the exhaust port. A valve is coupled to the cylinder head and movable relative to the cylinder head to selectively open the combustion chamber to one of the intake port and the exhaust port. A valve spring is positioned between the valve and the cylinder head and biases the valve to a closed position. A thermally insulating washer is positioned between the cylinder head and the valve spring. | 05-21-2009 |
John Cullen, Highland, CA US
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20120103247 | DEVICE AND METHOD FOR TOOL IDENTIFICATION AND TRACKING - A method for visual tool identification employing unique indicia as an identifier of an owner of a tool. The indicia identifiers are assigned by a provider and a database of tools owned and bearing said indica is maintained. The unique indicia identifier is preferably discernable from a distance such as further than the unaided eye may recognize a face so that third parties may identify tools and their owners from a distance. | 05-03-2012 |
John Cullen, Appleton, WI US
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20120108120 | EXTRUSION LAMINATE USEFUL IN INSULATION FACINGS AND TAPE BACKINGS - A facing or backing, that comprises a laminated film including an outside layer, a core layer, and an inside layer; a scrim, a laminating extrudate and a metal foil wherein at least the laminated film has an opacity and stiffness similar to paper and contains a fire retardant. In one embodiment, the structures are designed to replace the traditional ASJ (all service jacket) and FSK (foil scrim kraft) paper laminations that are used in insulation facings and HVAC tapes. | 05-03-2012 |
John S. Cullen, Mequon, WI US
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20090001705 | REAR FENDER ASSEMBLY - A rear fender assembly for a vehicle is provided. The rear fender assembly has an outer fender having an inner surface, an inner fender having an outer surface connected with the inner surface of the outer fender, and an upper bracket sandwiched between the inner surface of the outer fender and the outer surface of the inner fender. The upper bracket has an outer surface connected with the inner surface of the outer fender. The upper bracket forms an upper protrusion which extends from the outer surface of the upper bracket through a first opening defined by the outer fender. | 01-01-2009 |
John W. Cullen, Boston, MA US
Patent application number | Description | Published |
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20150088302 | INTER-FACILITY TRANSPORT IN INVENTORY MANAGEMENT AND FULFILLMENT SYSTEMS - In an infrastructure that uses a mobile order fulfillment system, robotic drive units may be dispatched and instructed to bring inventory holders to a workstation where at least one of the inventory holders is packed and prepared for shipment. The robotic drive units are then instructed to move the prepared inventory holder to a transport vehicle such as a truck. Fiducial marks may be removably placed within the transport vehicle to aid navigation of the robotic drive units. At a destination facility, additional robotic drive units may be instructed to move the inventory holders from the truck and place the inventory holders at appropriate storage locations. | 03-26-2015 |
Jon P. Cullen, Churchville, NY US
Patent application number | Description | Published |
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20100010498 | IOL Injector Comprising a Moveable Side Wall - An injector for inserting an intraocular lens (IOL) into an eye, comprising: a first side wall and a second side wall which are movable relative to one another, each side wall including a void, the voids positioned opposite one another in a direction perpendicular to a longitudinal axis of the injector. The injector may be in a combination with the IOL, the IOL disposed on a portion of the injector. The IOL may be in an unstressed state. A first portion of a haptic of the IOL may extend into the void in the first side wall. | 01-14-2010 |
20110152872 | INTRAOCULAR LENS INJECTOR INCLUDING A SHAPED SPRING - An intraocular lens (IOL) injector comprising an injector body having a lumen defined by a lumen wall, and a plunger adapted to slide within the lumen. The plunger is coupled to a spring having a plurality of coils, the plurality comprising at least one coil of a first outer diameter and at least one coil of second outer diameter that is different than the first outer diameter. | 06-23-2011 |
20110245840 | INTRAOCULAR LENS INJECTOR SYSTEM - An intraocular lens (IOL) assembly packaged for shipping, comprising an IOL injector component having a lumen wall, and an intraocular lens, at least one of the lumen wall and the optic comprising a first lens retention feature for impeding progress of the lens through said lumen toward the distal end. An IOL injector for injecting an IOL, comprising at least two projections extending from said lumen wall, the projections being configured and arranged to interfere with said soft tip prior to and during engagement of said soft tip with the IOL. An intraocular lens storage system, comprising a receptacle within the container, and a tapered portion, the tapered portion and the receptacle permitting a user's fingers to extend into the container to grasp a portion of a shuttle in the receptacle and remove the shuttle form the container, the receptacle defining a volume in which liquid is confined, the volume of the receptacle being less than the volume of the container. | 10-06-2011 |
20120289969 | Intraocular Lens Injector System - An intraocular lens (IOL) assembly packaged for shipping, comprising an IOL injector component having a lumen wall, and an IOL, at least one of the lumen wall and the optic comprising a first lens retention feature for impeding progress of the lens through said lumen toward the distal end. An IOL injector for injecting an IOL, comprising at least two projections extending from said lumen wall, the projections being configured and arranged to interfere with said soft tip prior to and during engagement of said soft tip with the IOL. An intraocular lens storage system, comprising a receptacle within the container, and a tapered portion, the tapered portion and the receptacle permitting a user's fingers to extend into the container to grasp a portion of a shuttle in the receptacle and remove the shuttle form the container. | 11-15-2012 |
20140074107 | INTRAOCULAR LENS INJECTOR ASSEMBLY INCLUDING A SHUTTLE AND METHOD OF USING SAME - An intraocular lens (IOL) injector assembly comprising an injector body having a shuttle reception opening defined at least in part by a first sidewall and a second sidewall, and a shuttle comprising a first wing including a first portion of a shuttle lumen wall and a second wing including a second portion of a shuttle lumen wall. The first wing and the second wing are coupled together by a hinge. When in a closed state, the first portion of the shuttle lumen wall and the second portion of the shuttle lumen wall define at least a portion of an operative shuttle lumen. The shuttle and sidewalls are configured such that the first wing and the second wing interfere with the first sidewall and the second sidewall, respectively, as the shuttle passes through the shuttle reception opening, such that the closed state of the shuttle is attained. | 03-13-2014 |
Joseph A. Cullen, Waterloo, IA US
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20130080010 | Clutch Protection System - A vehicle having a chassis, an engine supported by the chassis, a clutch assembly and a controller. The clutch assembly contains a clutch that is coupled to the engine. The controller executes a method to protect the clutch, the method including the steps of calculating, comparing and derating. The calculating step includes calculating the amount of energy being absorbed by the clutch. The comparing step compares the amount of energy to a predetermined limit. The derating step derates the engine dependent upon whether the amount of energy exceeded the predetermined limit in the comparing step. | 03-28-2013 |
Joseph Robert Cullen, New York, NY US
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20140373392 | NOISE REDUCING FOOTWEAR - The present invention is drawn generally to footwear, and more specifically, to footwear having reduced noise and impact characteristics. According to the invention noise generated by the impact of the footfall when in contact with hard floors is reduced by an outer sole with certain hardness and a sound reducing insole which comprising a material of high indentation forced deflection (IFD) weight having a minimum thickness of ¼ to a maximum ¾ inch, and an optimal thickness of about ½ inch. Also, the footwear comprises an upper portion attached to the outer sole to provide comfort and foot protection. | 12-25-2014 |
Kim Cullen, San Francisco, CA US
Patent application number | Description | Published |
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20110287528 | Devices, Systems, and Methods Related to Analyte Monitoring and Management - Analyte monitoring devices, systems, and methods are provided that relate to: enabling different application features on a data processing device for analyte monitoring devices with different analyte monitoring features; programming analyte monitoring devices in advance; personalizing an analyte monitoring device; graphically representing a remaining insulin level in a user body; and graphically representing analyte measurement related data for on-demand readings; protecting access to feature of an analyte monitoring device. | 11-24-2011 |
Kimberly J. Cullen, San Francisco, CA US
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20140089128 | VIDEO MESSAGE CAPTURE AND DELIVERY FOR ONLINE PURCHASES - Techniques for delivering a video message from a purchaser of an order to a recipient of the order are described. An order for one or more items is received, the order specifying a recipient and having an association with a purchaser. The order further specifies to deliver a video message from the purchaser to the recipient. Embodiments receive a video message from the purchaser. The order for the one or more items is fulfilled. Embodiments transmit at least an indication of the video message to the recipient. | 03-27-2014 |
Leslie D. Cullen, Meridian, ID US
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20090249721 | INSULATIVE SIDING APPARATUS AND METHOD OF MAKING THE SAME - The present invention is (in some embodiments) a system of decorative siding panels made from high-density expanded polystyrene (EPS) foam, such panels configured for overlapping, having interlocking tongue and groove structure. These panels for covering a surface, such as wall sheathing, of a structure. | 10-08-2009 |
20100242398 | INSULATIVE SIDING APPARATUS AND METHOD OF MAKING THE SAME - A system of interlocking decorative panels having a stone decorative element. | 09-30-2010 |
Mark Cullen, Reno, NV US
Patent application number | Description | Published |
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20110108465 | TREATMENT OF CRUDE OIL FRACTIONS, FOSSIL FUELS, AND PRODUCTS THEREOF - In crude oil fractions, fossil fuels, and organic liquids in general in which it is desirable to reduce the levels of sulfur-containing and nitrogen-containing components, the process reduces the level of these compounds via the application of heat, an oxidizing agent and, preferably, sonic energy. The invention is performed either as a continuous process or a batch process, and may further include optional steps of centrifugation or hydrodesulfurization. | 05-12-2011 |
20110226670 | PROCESS FOR REMOVING SULFUR FROM HYDROCARBON STREAMS USING HYDROTREATMENT, FRACTIONATION AND OXIDATION - Methods for removing sulfur from hydrocarbon streams using the sequential application of hydrodesulfurization, fractionation and oxidation. The hydrodesulfurization step is operative to remove easily-hydrogenated sulfur species, such as sulfides, disulfides and mercaptans. The resultant stream is then fractionated at a select temperature range to generate a sub-stream that is sulfur-rich with the sulfur species resistant to removal by hydrodesulfurization. The sub-stream is then isolated and subjected to an oxidative process operative to oxidize the sulfur species to sulfones or sulfoxides, which may then be removed by a variety of conventional methods, such as absorption. Alternatively, the methods may comprise using the sequential application of fractionation to generate a sulfur-rich sub-stream followed by oxidation and subsequent removal of the sulfur species present in the sub-fraction. The latter methods are ideally suited for transmix applications. | 09-22-2011 |
Matthew Cullen, Braintree, MA US
Patent application number | Description | Published |
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20120214824 | PROTEOSTASIS REGULATORS - The present invention is directed to compounds of Formulae (I), (II), (III), (IV), (V), (VI), (VII), and (VIII), pharmaceutical compositions thereof and methods of use thereof in the treatment of conditions associated with a dysfunction in proteostasis. | 08-23-2012 |
20120316193 | PROTEOSTASIS REGULATORS - The present invention is directed to compounds having the Formulae (Ia-Ie), (II), (IIIa-IIId), (IVa-IVc), (Va-Vb), (VIa-VIe), (VII), (VIIIa-VIIIc), and (IX), pharmaceutically acceptable salts, prodrugs and solvates thereof, compositions of any of thereof and methods for the treatment of a condition associated with a dysfunction in proteostasis comprising an effective amount of these compounds. | 12-13-2012 |
20130072473 | COMPOUNDS FOR TREATING PROTEIN FOLDING DISORDERS - The present invention is directed to compounds of Formulae (I), (IIa-IIh), (IIIa-IIIe), (IVa-IVc), (Va-V1), (VIa-VII), (VII), (VIII) and (IX), pharmaceutical compositions thereof and methods of use thereof in the treatment of conditions associated with a dysfunction in proteostasis. | 03-21-2013 |
Michelle Cullen, Northbrook, IL US
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20090281622 | Nasal fluid relief plug - A nasal plug for preventing excessive fluid discharge from a nasal passage includes a plug element fabricated from an absorbent material. The plug element has a size and configuration adapted and constructed to fit into a human nasal passage. A shaft portion extends from the plug element. The shaft portion is formed as an extension of the plug element and is fabricated from the same material as the plug element. A flexible sheathing is provided on the shaft portion. | 11-12-2009 |
Michelle Cullen, Chandler, AZ US
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20090200184 | VENTILATED TOOTHBRUSH HOLDER - A ventilated toothbrush holder having filtered ventilation is provided. The toothbrush holder has a container, or first web, and a re-closable cover, or second web flexibly coupled to the first web. In a first embodiment, the second web has an opening that is covered by a fine-mesh polymeric filter that resists the entry of water and other liquids but allows the flow of air. In a second embodiment, the first web also has an opening covered by the same type of filter to enhance air flow into the first web and out of the second web. An exemplary shape is claimed, but other embodiments are not limited as to shape. An insert for supporting toothbrushes, adapted in shape to the first web, is disclosed. | 08-13-2009 |
Patrick M. Cullen, Dallas, TX US
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20090024187 | MULIT-PROGRAMMABLE TRIAL STIMULATOR - Disclosed are systems and methods which provide trial stimulators suited for use interoperatively and during patient trial. Trial stimulator embodiments provide a patient interface and/or clinician interface which appears and functions substantially the same as an interface of a pulse generator controller which will be used after a trial period. A compliance monitor feature may be provided to facilitate verifying the proper use of the trial stimulator during a trial period. A diagnostic feature may be provided to facilitate verifying proper operation of various aspects of a trial stimulator, such as electrode impedance analysis. Trial stimulators of embodiments provide stimulation to a plurality of tissues and/or areas of the body, such as spinal cord stimulation, deep brain stimulation, etcetera. Embodiments provide for multi-electrode stimulation and multi-stimulation programs. Embodiments are configured to provide active discharge of stimulation pulses as well as to utilize constant current sources in providing the stimulation pulses. | 01-22-2009 |
20110208265 | MULTI-PROGRAMMABLE TRIAL STIMULATOR - Disclosed are systems and methods which provide trial stimulators suited for use interoperatively and during patient trial. Trial stimulator embodiments provide a patient interface and/or clinician interface which appears and functions substantially the same as an interface of a pulse generator controller which will be used after a trial period. A compliance monitor feature may be provided to facilitate verifying the proper use of the trial stimulator during a trial period. A diagnostic feature may be provided to facilitate verifying proper operation of various aspects of a trial stimulator, such as electrode impedance analysis. Trial stimulators of embodiments provide stimulation to a plurality of tissues and/or areas of the body, such as spinal cord stimulation, deep brain stimulation, etcetera. Embodiments provide for multi-electrode stimulation and multi-stimulation programs. Embodiments are configured to provide active discharge of stimulation pulses as well as to utilize constant current sources in providing the stimulation pulses. | 08-25-2011 |
20130211477 | SYSTEM AND METHOD FOR DEFINING STIMULATION PROGRAMS INCLUDING BURST AND TONIC STIMULATION - In one embodiment, a method for defining a stimulation program for electrical stimulation of a patient, the method comprising: providing a single screen user interface that comprises a first plurality of controls and a second plurality of controls, the first plurality of controls allowing selection of multiple stimulation parameters for a plurality of stimulation sets, the second plurality of controls allowing selection of multiple stimulation parameters defining burst stimulation and tonic stimulation; receiving user input in one or more of the second plurality of controls; and automatically modifying parameters for one or more stimulation sets in response to receiving the user input in one or more of the second plurality of controls and modifying values displayed in one or more controls of the first plurality of controls according to the modified parameters, the modified parameters reflecting a stimulation program that includes an interleaved pattern of burst stimulation and tonic stimulation for delivery to the patient. | 08-15-2013 |
Peter Cullen, Atlanta, GA US
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20090326977 | Systems and Methods for Providing Drug Samples to Patients - Systems and methods for processing drug sample prescription transactions that determine whether a drug to be prescribed is eligible for sampling and/or whether the patient is eligible for sampling that drug. A prescription transaction for that drug is created and transmitted to a switch provider and is then routed to a pharmacy for prescription fulfillment. Once the prescription has been filled a message may be sent to the prescribing clinician. Moreover, the pharmacy may generate a prescription claim to be adjudicated by a claim processor where the claim specifies voucher and/or coupon information associated with the drug to be sampled that is taken into consideration either prior to or during claim adjudication. A database containing patient and/or drug information may be used to track a patients' receipt of drug samples as well as used for analyzing and/or reporting on the use of the drug sampling prescription based system. | 12-31-2009 |
20090327363 | SYSTEMS AND METHODS FOR PROCESSING ELECTRONICALLY TRANSMITTED HEALTHCARE RELATED TRANSACTIONS - Systems and methods for the processing, modifying, and/or performance of a clinical, administrative and/or financial “value-add” service to an electronic healthcare related transaction from a healthcare provider to a third party such as a pharmacy. A prescription switch provider receives an incoming transaction from a healthcare provider system. The switch provider may then parse the transaction to review or modify data contained in the transaction and/or perform a value-add service or function based on the data contained in the transaction. Alternatively, the switch provider may copy the transaction for parallel processing. The transaction may be forwarded to a third party system, and a response message from the switch provider or the third party may be transmitted to the healthcare provider system pertaining to the modified transaction data and/or value-add service performed. | 12-31-2009 |
Robert M. Cullen, Bethel Park, PA US
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20140023781 | Methods of Use of Calcium Hexa Aluminate Refractory Linings and/or Chemical Barriers In High Alkali or Alkaline Environments - A method for improving the insulating character/and or penetration resistance of a surface comprising lining a surface of a lime kiln, a cement kiln, a roasting kiln, a thermal oxidizer, or a fluidized bed reactor that is subject to wear by an alkali environment and/or an alkaline environment with a refractory composition comprising a refractory aggregate consisting essentially of a calcium hexa aluminate clinker having the formula CA | 01-23-2014 |
Robert M. Cullen, Temple, NH US
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20090092385 | UNDERWATER CAMERA ASSEMBLY - An underwater camera assembly including a through hull housing having a passage extending therethrough. A flexible camera insert is positioned within the passage of the through hull housing and has a first end with a viewing window secured thereto, and a first sealing region for sealing the passage in a water tight manner. | 04-09-2009 |
20100054084 | Fan beam transducer assembly - A transducer assembly including a fan beam transducer having a beam generation axis for generating a fan shaped acoustic beam along the beam generation axis. The fan shaped acoustic beam can have a generally elliptical cross sectional shape with a major axis and a minor axis across a plane generally perpendicular to the beam generation axis. The transducer can be housed in a housing and have a direction of travel axis. The fan shaped acoustic beam can be rotatable relative to the direction of travel axis. The housing can have a release locking arrangement for rotationally releasing and locking the position of the fan shaped acoustic beam for orienting at least one of the major axis and minor axis of the fan shaped acoustic beam at a desired position relative to the direction of travel axis. | 03-04-2010 |
20120272726 | Precipitation Sensor - A precipitation sensor including a cantilevered sensor member having a cantilevered portion and an upper and a lower surface extending on opposite sides of the cantilevered portion. The sensor member can receive falling precipitation on the upper surface and vibrate when struck by such precipitation. The cantilevered portion can have outer perimeter edges that are sloped downwardly for shedding the precipitation off the cantilevered portion. An electromechanical sensor can be incorporated with at least a part of the cantilevered portion of the sensor member for sensing the vibrations of the sensor member caused by the precipitation, and generating an electrical response from which precipitation properties can be determined. A support structure can be connected to the lower surface of the cantilevered portion at about a central region of the sensor member for supporting the sensor member. The cantilevered portion extends outwardly beyond the support structure. | 11-01-2012 |
20140245829 | PRECIPITATION SENSOR - A precipitation sensor including a cantilevered sensor member having a cantilevered portion and an upper and a lower surface extending on opposite sides of the cantilevered portion. The sensor member can receive falling precipitation on the upper surface and vibrate when struck by such precipitation. The cantilevered portion can have outer perimeter edges that are sloped downwardly for shedding the precipitation off the cantilevered portion. An electromechanical sensor can be incorporated with at least a part of the cantilevered portion of the sensor member for sensing the vibrations of the sensor member caused by the precipitation, and generating an electrical response from which precipitation properties can be determined. A support structure can be connected to the lower surface of the cantilevered portion at about a central region of the sensor member for supporting the sensor member. The cantilevered portion extends outwardly beyond the support structure. | 09-04-2014 |
Schuyler Cullen, San Jose, CA US
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20150042743 | HYBRID VISUAL COMMUNICATION - Exemplary embodiments for visual communication between a first device and a second device, comprising: using data from a camera system to create a 3D mesh model of a first device user, wherein the 3D mesh model is made available for storage on the second device for subsequent display on the second device; during the visual communication session between the first device and the second device, receiving sensor data from a sensor array, including image data capturing changing facial expressions and motion of the first device user; using the image data to determine 3D mesh model updates; transmitting the 3D mesh model updates to the second device for the second device to update display of the 3D mesh model of the first device user; and receiving from the second device for display on the first device at least one of a 2D video stream or updates to a 3D mesh model of a second device user. | 02-12-2015 |
Shawn Cullen, Metamora, IL US
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20130248276 | Magnetic Brake for Machine Steering Feedback - Resistance feedback is provided to a machine operator via a joystick configured to steer the machine. An electrically actuated magnetic feedback brake unit is associated with the joystick for selectively resisting movement of the joystick. Haptic feedback is provided by determining a machine speed at which the machine is travelling, mapping the determined machine speed to a corresponding joystick resistance value, and mapping the corresponding joystick resistance value to an actuation current. The electrically actuated magnetic feedback brake unit is then actuated at a current substantially exceeding the actuation current until a predetermined level of actuation is reached. Once the predetermined level of actuation is reached, the electrically actuated magnetic feedback brake unit is driven at the actuation current. | 09-26-2013 |
Shawn I. Cullen, Metamora, IL US
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20110146261 | SYSTEM AND METHOD FOR CONTROLLING AN ELECTRO-HYDRAULIC CHARGING SYSTEM - The disclosure describes, in one aspect, a control system for charging an electro-hydraulic charging system. The control system including at least one sensor operatively coupled to an engine for sensing at least one engine parameter indicative of an operating status of the engine and a controller adapted to charge the charging system when the operating status of the engine is determined to be stable. | 06-23-2011 |
20140182277 | Electro-Hydraulic Steering System with Spool-Based Steering Event Detection - An electro-hydraulic steering system for an articulated machine includes an electrical circuit and a hydraulic circuit. The electrical circuit includes a controller, an electro-hydraulic valve assembly, and a spool position system. The hydraulic circuit includes a pump, at least one cylinder in selective fluid communication with the pump, and the valve assembly. The controller includes a computer-readable storage medium storing a steering system monitoring application which performs several steps. A desired flow of pressurized fluid to each cylinder and a desired spool position for the spool of the electro-hydraulic valve assembly, based upon the desired flow of pressurized fluid, are determined. The desired spool position and an actual spool position are compared to determine a spool-based flow error, which is summed over a period of time to determine a cumulative spool-based flow error. An event warning is issued when the cumulative spool-based flow error exceeds a threshold. | 07-03-2014 |
Shawn Ivor Cullen, Peoria, IL US
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20080238352 | Operator-control device for a machine - A machine includes an operator seat and an armrest adjacent the operator seat. The machine may also include a control system, which may include a control handle extending at least partially upward from the armrest. The control system may also include a force feedback device drivingly connected to the control handle and operable to supply feedback force to the control handle. The force-feedback device may include at least one of an actuator or a brake. Additionally, the control system may automatically adjust the magnitude of the feedback force supplied to the control handle by the force feedback device in at least some circumstances. | 10-02-2008 |
Steven Cullen, Lake Villa, IL US
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20110144343 | PROCESS FOR PREPARING CANNABINOID RECEPTOR LIGANDS - A process for the preparation of compounds of formula (I) or a salt thereof | 06-16-2011 |
Steven Cullen, Astoria, OR US
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20090241479 | MOBILE BAGGING MACHINE - Mobile bagging machine systems and methods may relate to a mobile bagging machine that includes a variable-width tunnel, a variable-speed rotor, a relatively narrow rotor of large diameter and increased effective surface area, at least one material reservoir, a material conveyor system capable of continuous material processing during exchange of unloading vehicles, and/or an overall width less than approximately three meters. | 10-01-2009 |
20090241480 | MOBILE BAGGING MACHINE ROTOR ASSEMBLY AND TRANSMISSION - Mobile bagging machine systems and methods may relate to a mobile bagging machine that includes a variable-width tunnel, a variable-speed rotor, a relatively narrow rotor of large diameter and increased effective surface area, at least one material reservoir, a material conveyor system capable of continuous material processing during exchange of unloading vehicles, and/or an overall width less than approximately three meters. | 10-01-2009 |
20090241484 | MOVABLE FEED TABLE AND RADIATORS - Mobile bagging machine systems and methods may relate to a mobile bagging machine that includes a variable-width tunnel, a variable-speed rotor, a relatively narrow rotor of large diameter and increased effective surface area, at least one material reservoir, a material conveyor system capable of continuous material processing during exchange of unloading vehicles, and/or an overall width less than approximately three meters. | 10-01-2009 |
20090241488 | MOBILE BAGGING MACHINE TUNNEL - Mobile bagging machine systems and methods may relate to a mobile bagging machine that includes a variable-width tunnel, a variable-speed rotor, a relatively narrow rotor of large diameter and increased effective surface area, at least one material reservoir, a material conveyor system capable of continuous material processing during exchange of unloading vehicles, and/or an overall width less than approximately three meters. | 10-01-2009 |
20110162328 | Mobile Bagging Machine Tunnel - Mobile bagging machine systems and methods may relate to a mobile bagging machine that includes a variable-width tunnel, a variable-speed rotor, a relatively narrow rotor of large diameter and increased effective surface area, at least one material reservoir, a material conveyor system capable of continuous material processing during exchange of unloading vehicles, and/or an overall width less than approximately three meters. | 07-07-2011 |
20110167767 | MOBILE BAGGING MACHINE - Mobile bagging machine systems and methods may relate to a mobile bagging machine that includes a variable-width tunnel, a variable-speed rotor, a relatively narrow rotor of large diameter and increased effective surface area, at least one material reservoir, a material conveyor system capable of continuous material processing during exchange of unloading vehicles, and/or an overall width less than approximately three meters. | 07-14-2011 |
Steven C. Cullen, Lake Villa, IL US
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20120101031 | MACROCYCLIC HEPATITIS C SERINE PROTEASE INHIBITORS - The present invention relates to novel macrocyclic compounds and methods of treating a hepatitis C infection in a subject in need of such therapy with said macrocyclic compounds. The present invention further relates to pharmaceutical compositions comprising the compounds of the present invention, or pharmaceutically acceptable salts, esters, or prodrugs thereof, in combination with a pharmaceutically acceptable carrier or excipient. | 04-26-2012 |
20140287992 | MACROCYCLIC HEPATITIS C SERINE PROTEASE INHIBITORS - The present invention relates to novel macrocyclic compounds and methods of treating a hepatitis C infection in a subject in need of such therapy with said macrocyclic compounds. The present invention further relates to pharmaceutical compositions comprising the compounds of the present invention, or pharmaceutically acceptable salts, esters, or prodrugs thereof, in combination with a pharmaceutically acceptable carrier or excipient. | 09-25-2014 |
Steven Cramer Cullen, Lake Villa, IL US
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20140275546 | AZAADAMANTANE FORMATE ESTER AND PROCESS FOR PREPARING AZAADAMANTANE DERIVATIVES - A compound, (4s)-1-azaadamantane-4yl formate ester, is described. In addition, a process is described for preparing (4s)-1-azaadamantane-4yl formate ester, aminothiadiazole-phenyl phosphate salt, bromothiadizole-phenyl or (4s)-4-(5-phenyl-1,3,4-thiadiazol-2-yloxy)-1-azatricyclo[3.3.1.1 | 09-18-2014 |
Steven R. Cullen, Chinook, WA US
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20140137520 | FLUID EXTRACTION AND INJECTION SYSTEM FOR BAGGING MACHINERY - A bagging machine having a uniquely configured rotor that can be operated with a grill, enables removal or injection of fluid materials when filling a bag. In one mode, the rotor enables the removal or draining of an effluent created from the bagging process such as from silage. In another mode, the rotor enables the injection of a treatment agent such as an antifungal agent as material is bagged. | 05-22-2014 |
Steven R. Cullen, Astoria, OR US
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20100064641 | BAG INSTALLATION FOR BAGGING MACHINE - Bag installation for bagging machines may include bag installation systems and/or methods that provide efficient, convenient, safe, and/or simplified means and/or steps for installing a bag on, and/or maintaining bag on, a bagging machine. | 03-18-2010 |
Terence J. Cullen, Southampton, NY US
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20130006728 | SYSTEM AND METHOD FOR GOAL BASED SAVINGS - A method, performed by a server, for incentivizing school performance includes receiving score information corresponding to a student from a first user terminal and adding score information to a student profile corresponding to the student in a database. A credit adjustment value is calculated based on the received score information and a new total number of credits stored in the student profile is set to a sum of the credit adjustment value and a total number of credits previously stored in the student profile. A request for merchant offer information corresponding to the student profile is received from a second user terminal. For each of at least one merchant, a respective merchant offer is generated according to at least a portion of the total number of credits set in the student profile and information corresponding to the merchant. | 01-03-2013 |
20140052526 | SYSTEM AND METHOD FOR GOAL BASED SAVINGS - A method, performed by a server, for incentivizing school performance includes receiving score information corresponding to a student from a first user terminal and adding score information to a student profile corresponding to the student in a database. A credit adjustment value is calculated based on the received score information and a new total number of credits stored in the student profile is set to a sum of the credit adjustment value and a total number of credits previously stored in the student profile. A request for merchant offer information corresponding to the student profile is received from a second user terminal. For at least one merchant, a respective merchant offer is generated according to at least a portion of the total number of credits set in the student profile and information corresponding to the merchant. | 02-20-2014 |
Thomas Cullen, Ithaca, NY US
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20120064216 | COOKING GRILL - A cooking grill uses infrared radiant top-down heat from burning a solid carbonaceous fuel to cook food. The cooking grill includes a grill body having sidewalls, a fuel rack disposed substantially horizontally within the grill body and adapted to hold a carbonaceous solid fuel, and a food rack disposed substantially horizontally within the grill body below the fuel rack. A method of grilling a food item includes placing the food item in a food rack and inserting the food rack into a grill body in a substantially horizontal orientation, placing a solid carbonaceous fuel in a food rack in a substantially horizontal position above the food rack in the grill body, igniting the solid carbonaceous fuel, and removing the food rack from the grill body when the food is cooked. | 03-15-2012 |
Thomas Gerard Cullen, Milltown, NJ US
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20090061024 | COMPOSITIONS AND METHODS EMPLOYING NMDA ANTAGONISTS FOR ACHIEVING AN ANESTHETIC-SPARING EFFECT - Provided herein are compositions, combinations, and methods comprising NMDA antagonists including, but not limited to, NMDA glutamate receptor antagonists such as [2-(8,9-dioxo-2,6-diazabicyclo[5.2.0]non-1-(7)-en-2-yl)alkyl]phosphonic acid and derivatives thereof, which are effective in reducing the amount of anesthetic required to maintain anesthesia (i.e. to achieve an anesthetic-sparing effect). | 03-05-2009 |
20120116074 | METHODS FOR THE PREPARATION OF [2-(8,9-DIOXO-2,6-DIAZABICYCLO[5.2.0]NON-1(7)-EN-2-YL)ETHYL]PHOSPHONIC ACID AND PRECURSORS THEREOF - The present invention is directed to processes associated with the preparation of [2-(8,9-dioxo-2,6-diazabicyclo[5.2.0]non-1(7)-en-2-yl)ethyl]phosphonic acid (perzinfotel). | 05-10-2012 |
Tom Cullen, Santa Barbara, CA US
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20120263318 | SMART LINE-IN PROCESSING - Technology for smart line-in processing in an audio environment is disclosed. Particularly, the embodiments described herein provide automated source switching in an audio environment where a number of audio sources may exist and volume control. | 10-18-2012 |
20150086045 | Smart Line-In Processing in a Group - Technology for smart line-in processing in an audio environment is disclosed. An example playback device includes a line-in connector for receiving a first audio signal, a network interface, and a processor. A computer readable storage medium has stored instructions executable by the processor to determine that the first audio signal is present at the line-in connector, and, in response to determining that the first audio signal is present at the line-in connector, (i) cease playback of a second audio signal being played by the playback device, wherein the second audio signal is not present at the line-in connector, (ii) cause the playback device to play at least a first portion of the first audio signal, and (iii) cause the playback device to transmit, via the network interface, at least a second portion of the first audio signal to another playback device. | 03-26-2015 |
Valerie Cullen, Quincy, MA US
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20110038851 | TREATMENT OF SYNUCLEINOPATHIES - This invention relates generally to treating synucleinopathies in subjects that are not clinically diagnosed with a lysosomal storage disease, as well as associated methods of making medicaments and screening methods. | 02-17-2011 |
20130177549 | Treatment of Synucleinopathies - This invention relates generally to treating synucleinopathies in subjects that are not clinically diagnosed with a lysosomal storage disease, as well as associated methods of making medicaments and screening methods. | 07-11-2013 |
Valerie Christina Cullen, Squantum, MA US
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20100184803 | Treatment of Lysosomal Storage Diseases - Methods and compositions useful in the treatment or prevention of lysosomal storage diseases, such as Pompe's disease, Fabry's disease, Gaucher's disease, and Niemann-Pick disease, are provided. The treatment includes administering to a subject a farnesyl transferase inhibitor compound. The treatment may also include enzyme replacement therapy or gene therapy. | 07-22-2010 |
William Cullen, Cambridge, MA US
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20080256553 | Dynamic Subscription and Message Routing on a Topic between Publishing Nodes and Subscribing Nodes - A system for dynamic message routing on a topic between publishing nodes and subscribing nodes includes a plurality of message queues, at least one topic/node table, a subscribing module, a publishing module, and other modules to send messages between one or more publisher and one or more subscribers. These modules are coupled together by a bus in a plurality of nodes and provide for the dynamic message routing on a topic between publishing nodes and subscribing nodes. The message queues store messages at each node for delivery to subscribers local to that node. The topic/node table lists which clients subscribe to which topics, and is used by the other modules to ensure proper distribution of messages. The subscribing module is use to establish a subscription to a topic for that node. The publishing module is used to identify subscribers to a topic and transmit messages to subscribers dynamically. The other modules include various devices to optimize message communication in a publish/subscribe architecture operating on a distributed computing system. The present invention also includes a number of novel methods including: a method for publishing a message on a topic, a method for forwarding a message on a topic, a method for subscribing to messages on a topic, a method for automatically removing subscribers, a method for direct publishing of messages, and methods for optimizing message transmission between nodes. | 10-16-2008 |
20140195622 | DYNAMIC SUBSCRIPTION AND MESSAGE ROUTING ON A TOPIC BETWEEN PUBLISHING NODES AND SUBSCRIBING NODES - A system for dynamic message routing on a topic between publishing nodes and subscribing nodes includes a plurality of message queues, at least one topic/node table, a subscribing module, a publishing module, and other modules to send messages between one or more publisher and one or more subscribers. Methods include: a method for publishing a message on a topic, a method for forwarding a message on a topic, a method for subscribing to messages on a topic, a method for automatically removing subscribers, a method for direct publishing of messages, and methods for optimizing message transmission between nodes. | 07-10-2014 |
William K. Cullen, Pittsburgh, PA US
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20140097834 | SYSTEMS AND METHODS FOR STEAM GENERATOR TUBE ANALYSIS FOR DETECTION OF TUBE DEGRADATION - The systems and methods of the invention pertain to analyzing steam generator tube data for the detection of wear. Further, the invention is capable of performing a comparison of current tube signal data to baseline or historic tube signal data, e.g., from previous and/or the first, in-service inspection of the steam generator. The systems and methods are automated and can generate results to show potential tube-to-tube contact wear areas as well as the progression of tube-to-tube gap reduction within a steam generator tube bundle. In certain embodiments, the invention is capable of comparing current and historical eddy current data to determine the difference that may be related to degradation or other interested phenomena, and of processing and trending historical comparison results to establish normal variance and detect abnormal variances. | 04-10-2014 |