Patent application number | Description | Published |
20090105208 | Substituted Piperazines as CB1 Antagonists - Compounds of Formula (I): | 04-23-2009 |
20100029607 | Substituted Piperazines as CB1 Antagonists - Compounds of Formula (I): | 02-04-2010 |
20100249144 | SUBSTITUTED PIPERAZINES AS CB1 ANTAGONISTS - Compounds of Formula (I) or pharmaceutically acceptable salts, solvates, or esters thereof, are useful in treating diseases or conditions mediated by CB | 09-30-2010 |
20100286160 | SUBSTITUTED PIPERAZINES AS CB1 ANTAGONISTS - Compounds of Formula (I): or pharmaceutically acceptable salts, solvates, or esters thereof, are useful in treating diseases or conditions mediated by CB1 receptors, such as metabolic syndrome and obesity, neuroinflammatory disorders, cognitive disorders and psychosis, addiction (e.g., smoking cessation), gastrointestinal disorders, and cardiovascular conditions. | 11-11-2010 |
20120108505 | THIOPHENES AS GLUCAGON RECEPTOR ANTAGONISTS, COMPOSITIONS, AND METHODS FOR THEIR USE - The present invention relates to compounds of the general formula (I): wherein R | 05-03-2012 |
20120178789 | NOVEL PYRROLIDINES AS GLUCAGON RECEPTOR ANTAGONISTS, COMPOSITIONS, AND METHODS FOR THEIR USE - The present invention relates to compounds of the general formula: (I) wherein ring B, R | 07-12-2012 |
20120183563 | IMINOTHIADIAZINE DIOXIDE COMPOUNDS AS BACE INHIBITORS, COMPOSITIONS AND THEIR USE - In its many embodiments, the present invention provides certain iminothiadiazine dioxide compounds, including compounds Formula (I): (I) and include stereoisomers thereof, and pharmaceutically acceptable salts of said compounds stereoisomers, wherein each of R | 07-19-2012 |
20120189642 | IMINOTHIADIAZINE DIOXIDE COMPOUNDS AS BACE INHIBITORS, COMPOSITIONS, AND THEIR USE - In its many embodiments, the present invention provides certain iminothiadiazine dioxide compounds, including compounds Formula (a) and include tautomers, solvates, prodrugs, esters, and deuterates thereof, and pharmaceutically acceptable salts of said compounds, tautomers, solvates, prodrugs, esters, and deuterates, wherein each of R | 07-26-2012 |
20140023667 | PYRROLIDINE-FUSED THIADIAZINE DIOXIDE COMPOUNDS AS BACE INHIBITORS, COMPOSITIONS, AND THEIR USE - In its many embodiments, the present invention provides certain iminothiadiazine dioxide compounds, including compounds Formula (I): and tautomers and stereoisomers thereof, and pharmaceutically acceptable salts of said compounds, said tautomeros and said stereoisomers, wherein each of W, Z, R | 01-23-2014 |
20140023668 | C5-C6 OXACYCLIC-FUSED THIADIAZINE DIOXIDE COMPOUNDS AS BACE INHIBITORS, COMPOSITIONS, AND THEIR USE - In its many embodiments, the present invention provides certain iminothiadiazine dioxide compounds, including compounds Formula: (I) and tautomers and stereoisomers thereof, and pharmaceutically acceptable salts of said compounds, said tautomeros and said stereoisomers, wherein each of ring A, ring B, ring C, R | 01-23-2014 |
20140128382 | 5-SUBSTITUTED IMINOTHIAZINES AND THEIR MONO- AND DIOXIDES AS BACE INHIBITORS, COMPOSITIONS, AND THEIR USE - The present invention discloses certain iminothiazine compounds and mono- and dioxides thereof, including compounds Formula (I): and tautomers and stereoisomers thereof, and pharmaceutically acceptable salts of said compounds, said tautomers and said stereoisomers, wherein each of variables shown in the formula are as defined herein. The compounds of the invention may be useful as BACE inhibitors and/or for the treatment and prevention of various pathologies related thereto. Pharmaceutical compositions comprising one or more such compounds (alone and in combination with one or more other active agents), and methods for their preparation and uses, including Alzheimer's disease, are also disclosed. | 05-08-2014 |
20140206675 | IMINOTHIADIAZINE DIOXIDE COMPOUNDS AS BACE INHIBITORS, COMPOSITIONS, AND THEIR USE - In its many embodiments, the present invention provides certain iminothiadiazine dioxide compounds, including compounds Formula (I): (I) and include stereoisomers thereof, and pharmaceutically acceptable salts of said compounds stereoisomers, wherein each of R | 07-24-2014 |
20140296221 | IMINOTHIADIAZINE DIOXIDE COMPOUNDS AS BACE INHIBITORS, COMPOSITIONS, AND THEIR USE - In its many embodiments, the present invention provides certain iminothiadiazine dioxide compounds, including compounds Formula (I): | 10-02-2014 |
20140296222 | IMINOTHIADIAZINE DIOXIDE COMPOUNDS AS BACE INHIBITORS, COMPOSITIONS, AND THEIR USE - In its many embodiments, the present invention provides certain iminothiadiazine dioxide compounds, including compounds Formula (I): | 10-02-2014 |
20150274716 | TRICYCLIC SUBSTITUTED THIADIAZINE DIOXIDE COMPOUNDS AS BACE INHIBITORS, COMPOSITIONS AND THEIR USE - In its many embodiments, the present invention provides certain iminothiazine dioxide compounds, including compounds Formula (I): and tautomers and stereoisomers thereof, and pharmaceutically acceptable salts of said compounds, said tautomeros and said stereoisomers, wherein the middle ring (referred to herein as “ring B”) of the tricyclic substituent is an optionally substituted 5-membered ring, and each of the remaining variables shown in the formula are as defined herein. The novel compounds of the invention are useful as BACE inhibitors and/or for the treatment and prevention of various pathologies related thereto. Pharmaceutical compositions comprising one or more such compounds (alone and in combination with one or more other active agents), and methods for their preparation and use, including Alzheimer's disease, are also disclosed. | 10-01-2015 |
20150284379 | TRICYCLIC SUBSTITUTED THIADIAZINE DIOXIDE COMPOUNDS AS BACE INHIBITORS, COMPOSITIONS AND THEIR USE - In its many embodiments, the present invention provides certain iminothiazine dioxide compounds, including compounds Formula (I): (I) and tautomers and stereoisomers thereof, and pharmaceutically acceptable salts of said compounds, said tautomers and said stereoisomers, wherein the middle ring (referred to herein as “ring B”) of the tricyclic substituent is an optionally substituted 6-membered ring, and each of the remaining variables shown in the formula are as defined herein. The novel compounds of the invention are useful as BACE inhibitors and/or for the treatment and prevention of various pathologies related thereto. Pharmaceutical compositions comprising one or more such compounds (alone and in combination with one or more other active agents), and methods for their preparation and use, including Alzheimer's disease, are also disclosed. | 10-08-2015 |
20150307465 | Iminothiadiazine Dioxide Compounds as BACE Inhibitors, Compositions and Their Use - In its many embodiments, the present invention provides certain iminothiadiazine dioxide compounds, including compounds Formula (I): | 10-29-2015 |
Patent application number | Description | Published |
20080232358 | Data Distribution in a Distributed Telecommunications Network - A technique is disclosed that enables a set of information to be represented by data packets, where those data packets can then be distributed as needed throughout the telecommunications system that uses the data. The data packet of the illustrative embodiment is an autonomous encapsulation of data, a subsection of a data model at a certain time in relation to other data in the system at another time. The data packet is identified at a particular time and value with a globally unique identifier. Relationships of the data packet to other data packets are made known by using references to the other packets. As a result, referenced data packets are retrieved throughout the system based on their relationships to each other. Whenever a data packet is transmitted or received, each node involved in the transmission applies rules that determine where the data has to be transmitted to and what to do with the data when received. | 09-25-2008 |
20080232556 | Keyword Alerting in Conference Calls - A conferencing system is disclosed in which a participant to a conference call can program the embodiment to listen for one or more “keywords” in the conference call. The keywords might be a participant's name or words associated with him or her or words associated with his or her area of knowledge. The embodiments uses speech recognition technology to listen for those words. When the embodiments detects that those words have been spoken, the embodiment alerts the participant—using audible, visual, and/or tactile signals—that the participant's attention to the call is warranted. When the keywords are chosen wisely, the benefit can be great. | 09-25-2008 |
20080232570 | Automatic Reconstitution of Telecommunications Sessions - A telecommunications feature is disclosed that enables a person to disconnect from a telecommunications session (e.g., a telephone call, a chat session, a video conference, etc.) and to be automatically reconnected at a later time. For example, Fred might be required to participate in his project group's weekly conference call, but as a practical matter Fred really only need to participate at the beginning and end of the meeting. After the conference call begins and Fred learns that the meeting will end at 4:00 PM, Fred uses the present invention to program his telephone to disconnect from the conference call now and to automatically reconnect to the conference call at 3:45 PM. This gives Fred the opportunity to get some work done and yet not miss the end of the conference call. | 09-25-2008 |
20080233933 | Structured Conference Calls - A conference call is disclosed that is partitioned into two or more topics by a host. Participants to the conference call can then inform the illustrative embodiment which topic or topics they are interested in and where they can be reached over the course of the conference call. At that point, those people who are not interested in the immediate topic can hang up or put their terminal on mute or other go about their business. As the conference call progresses from topic to topic, the host, or another person, informs the illustrative embodiment which topic is next to be discussed. The illustrative embodiment then alerts the participants who indicated their interest in the topic if their terminal is on mute or standby and adds the participants that are not connected to the conference call at all. | 09-25-2008 |
20100080130 | Synchronization of Session-Initiation-Protocol Proxy Databases - An improvement in the design and operation of telecommunications networks is described in which when a caller's telecommunication terminal does not know the address of the called party's telecommunications terminal, the caller's telecommunication terminal contacts one Session Initiation Protocol Proxy server after another until the address of the called party's telecommunications terminal is found. Thereafter, one or more of the Session Initiation Protocol Proxy servers that did not have the address of the called party's telecommunications terminal are populated with that information for future use. | 04-01-2010 |
20100091768 | Coordination of User Information across Session Initiation Protocol-based Proxy Servers - An improvement in the design and operation of telecommunications networks is disclosed, in which when a calling party's telecommunication terminal does not know the address of the called party's terminal, the calling party's telecommunication terminal contacts its home Session Initiation Protocol (SIP) proxy server (or “home proxy”). Upon determining that it does not already have the called party's address, the home proxy employs one or more techniques in order to obtain that party's address, as well as to retain that address. The first technique of the illustrative embodiment features the usage of a registration event package, which includes SIP-based subscribe and notify mechanisms. The second technique of the illustrative embodiment features the usage of a data distribution service, which operates in a data distribution layer in contrast to utilizing, for example, a SIP mechanism. | 04-15-2010 |
20120033796 | Keyword Alerting in Conference Calls - A conferencing system is disclosed in which a participant to a conference call can program the embodiment to listen for one or more “keywords” in the conference call. The keywords might be a participant's name or words associated with him or her or words associated with his or her area of knowledge. The embodiments uses speech recognition technology to listen for those words. When the embodiments detects that those words have been spoken, the embodiment alerts the participant—using audible, visual, and/or tactile signals—that the participant's attention to the call is warranted. When the keywords are chosen wisely, the benefit can be great. | 02-09-2012 |
20120035930 | Keyword Alerting in Conference Calls - A conferencing system is disclosed in which a participant to a conference call can program the embodiment to listen for one or more “keywords” in the conference call. The keywords might be a participant's name or words associated with him or her or words associated with his or her area of knowledge. The embodiments uses speech recognition technology to listen for those words. When the embodiments detects that those words have been spoken, the embodiment alerts the participant—using audible, visual, and/or tactile signals—that the participant's attention to the call is warranted. When the keywords are chosen wisely, the benefit can be great. | 02-09-2012 |
Patent application number | Description | Published |
20080200242 | REAL-TIME INTERACTIVE WAGERING ON EVENT OUTCOMES - Systems and methods for real-time interactive wagering on event outcomes are presented. Clients are first qualified and given wagering limits before being allowed to interactively wager on event outcomes. Event outcomes may be based on, for example, financial markets and indices, sporting and entertainment events, casino performances, and natural phenomena such as weather and earthquakes. Events on which wagers can be placed include both those with known and unknown outcome probabilities, and wagers can be a fixed-odds type or a spread-bet type. Wager transactions, including acceptances and confirmations, are executed in real time. Clients can customize displays of events on which they are authorized to wager. Real-time client credit management, automatic dealer hedging, automatic price-spread adjustments, and automatic client and dealer defined wagering limits are also provided. | 08-21-2008 |
20100217659 | METHODS AND SYSTEMS FOR PROVIDING CROSSING MARKETS - Methods and systems for providing and implementing crossing markets are provided. These methods and systems preferably include facilitating trading at crossing markets by establishing crossing market trading rules, incentivizing crossing market participants, and improving the efficiency of crossing market trading. | 08-26-2010 |
20120100918 | REAL-TIME INTERACTIVE WAGERING ON EVENT OUTCOMES - Systems and methods for real-time interactive wagering on event outcomes are presented. Clients are first qualified and given wagering limits before being allowed to interactively wager on event outcomes. Event outcomes may be based on, for example, financial markets and indices, sporting and entertainment events, casino performances, and natural phenomena such as weather and earthquakes. Events on which wagers can be placed include both those with known and unknown outcome probabilities, and wagers can be a fixed-odds type or a spread-bet type. Wager transactions, including acceptances and confirmations, are executed in real time. Clients can customize displays of events on which they are authorized to wager. Real-time client credit management, automatic dealer hedging, automatic price-spread adjustments, and automatic client and dealer defined wagering limits are also provided. | 04-26-2012 |
20120203684 | SYSTEMS AND METHODS OR BID/OFFER SPREAD TRADING - A bid/offer spread market is presented that allows a trader to increase liquidity in traded items. A bid/offer spread market maker may make a bid/offer spread market. This bid/offer spread market may be made available to any market participant. In response to the spread market, an aggressor may respond to a bid or an offer with a hit or a take, respectively. In response to the hit or the take, the aggressor or bid/offer spread market maker, respectively, may create a separate underlying market using the selected (bid or offer) spread within a specified amount of time. The other party, a bid/offer spread trader, may trade on the quoted price within a specified amount of time, at which point a trade has occurred. | 08-09-2012 |
20130005444 | REAL-TIME INTERACTIVE WAGERING ON EVENT OUTCOMES - Systems and methods for real-time interactive wagering on event outcomes are presented. Clients are first qualified and given wagering limits before being allowed to interactively wager on event outcomes. Event outcomes may be based on, for example, financial markets and indices, sporting and entertainment events, casino performances, and natural phenomena such as weather and earthquakes. Events on which wagers can be placed include both those with known and unknown outcome probabilities, and wagers can be a fixed-odds type or a spread-bet type. Wager transactions, including acceptances and confirmations, are executed in real time. Clients can customize displays of events on which they are authorized to wager. Real-time client credit management, automatic dealer hedging, automatic price-spread adjustments, and automatic client and dealer defined wagering limits are also provided. | 01-03-2013 |
20130124379 | SYSTEMS AND METHODS FOR CREATING AND TRADING DYNAMIC SECURITIES - Systems and methods for creating and trading dynamic securities are provided. Dynamic securities according to the invention may preferably include any security or non-securitized investment. To form the dynamic security, a user may select a plurality of securities including stocks, bonds, baseball cards and modern art paintings to create a dynamic security. The selection may be limited to a pre-determined list of securities. | 05-16-2013 |
20130132253 | CF-30: METHODS AND SYSTEMS FOR TRADING OF FUTURES CONTRACTS FOR INTANGIBLE ASSETS - Methods and systems for trading of future contracts for intangible assets are provided. The methods and systems allow traders to access information on intangible asset futures contracts and future contract funds and to execute their trades in a computer-based futures exchange. Intangible assets include future royalties or revenues from artistic works or future salaries of professionals, for instance. The futures exchange system provides real-time trading status on the futures contracts or funds as well as detailed information on contract terms. Quotes may be matched automatically by the futures exchange. Sensitivity analysis of various factors on the outcome of futures contracts valuation may be provided. Additionally, offer and contract terms for categories of intangible assets may be standardized in the futures exchange for trading simplification. | 05-23-2013 |
20130159213 | SYSTEMS AND METHODS FOR FINANCIAL INSTRUMENT INSPECTION - Systems and methods for user-configurable financial instrument inspection are provided. A user may select the type of financial performance information and presentation format of the financial performance information to be displayed when the user selects a particular financial instrument. The user may associate a set of financial performance information and presentation format with a particular financial market for financial instruments. The financial instrument inspector may also facilitate trading of financial instruments. | 06-20-2013 |
Patent application number | Description | Published |
20140163960 | REAL - TIME EMOTION TRACKING SYSTEM - Devices, systems, methods, media, and programs for detecting an emotional state change in an audio signal are provided. A plurality of segments of the audio signal is received, with the plurality of segments being sequential. Each segment of the plurality of segments is analyzed, and, for each segment, an emotional state and a confidence score of the emotional state are determined. The emotional state and the confidence score of each segment are sequentially analyzed, and a current emotional state of the audio signal is tracked throughout each of the plurality of segments. For each segment, it is determined whether the current emotional state of the audio signal changes to another emotional state based on the emotional state and the confidence score of the segment. | 06-12-2014 |
20150074702 | SYSTEM AND METHOD FOR AUTOMATIC IDENTIFICATION OF KEY PHRASES DURING A MULTIMEDIA BROADCAST - Aspects of the subject disclosure may include, for example, a process that determines information from a first media stream including a number of keywords associated with viewing habits of a user. A second media stream of a media program is scanned for one of a word or phrase corresponding to a keyword of the number of keywords. A second keyword is determined based on the one of the word or phrase, and additional information associated with the second keyword is identified. Results associated with the additional information are provided to a multimedia device. Other embodiments are disclosed. | 03-12-2015 |
20150145995 | ENHANCED VIEW FOR CONNECTED CARS - Network connectivity is used to share relevant visual and other sensory information between vehicles, as well as delivering relevant information provided by network services to create an enhanced view of the vehicle's surroundings. The enhanced view is presented to the occupants of the vehicle to provide an improved driving experience and/or enable the occupants to take proper action (e.g., avoid obstacles, identify traffic delays, etc.). In one example, the enhanced view comprises information that is not visible to the naked eye and/or cannot be currently sensed by the vehicle's sensors (e.g., due to a partial or blocked view, low visibility conditions, hardware capabilities of the vehicle's sensors, position of the vehicle's sensors, etc.). | 05-28-2015 |
20150235655 | REAL-TIME EMOTION TRACKING SYSTEM - Devices, systems, methods, media, and programs for detecting an emotional state change in an audio signal are provided. A plurality of segments of the audio signal is received, with the plurality of segments being sequential. Each segment of the plurality of segments is analyzed, and, for each segment, an emotional state and a confidence score of the emotional state are determined. The emotional state and the confidence score of each segment are sequentially analyzed, and a current emotional state of the audio signal is tracked throughout each of the plurality of segments. For each segment, it is determined whether the current emotional state of the audio signal changes to another emotional state based on the emotional state and the confidence score of the segment. | 08-20-2015 |
20150364139 | SENSOR ENHANCED SPEECH RECOGNITION - A system for sensor enhanced speech recognition is disclosed. The system may obtain visual content or other content associated with a user and an environment of the user. Additionally, the system may obtain, from the visual content, metadata associated with the user and the environment of the user. The system may also include determining, based on the visual content and metadata, if the user is speaking. If the user is determined to be speaking, the system may obtain audio content associated with the user and the environment. The system may then adapt, based on the visual content, audio content, and metadata, one or more acoustic models that match the user and the environment. Once the one or more acoustic models are adapted and loaded, the system may enhance a speech recognition process or other process associated with the user. | 12-17-2015 |
20160026734 | Alert Driven Interactive Interface to a Website Mining System - Disclosed is a web server that includes a headlines module for automatically generating headlines based on data retrieved from a network (e.g., World Wide Web). The web server also includes an interactive agent for generating responses to inquiries relating to the headlines based on the data. | 01-28-2016 |
Patent application number | Description | Published |
20090132288 | SYSTEM AND METHOD FOR FACILITATING CENTRALIZED CANDIDATE SELECTION AND MONITORING SUBJECT PARTICIPATION IN CLINICAL TRIAL STUDIES - A system and method of facilitating centralized and standardized remote ratings of subjects in clinical trial studies includes providing training to raters located at one or more central rating sites such that the raters are trained to apply substantially similar criteria in determining whether a candidate is a qualified subject for the clinical trial and/or in the actual assessment, or information collection, phase of the clinical trail. By having centralized, consistently trained raters that are independent of clinical trial investigators, inter-rater reliability is enhanced and potential bias is reduced, thus increasing the effectiveness of the clinical trial results by providing more qualified subjects and more accurate results. | 05-21-2009 |
20100100397 | SYSTEM AND METHOD FOR FACILITATING CENTRALIZED CANDIDATE SELECTION AND MONITORING SUBJECT PARTICIPATION IN CLINICAL TRIAL STUDIES - A system and method of facilitating centralized and standardized remote ratings of subjects in clinical trial studies includes providing training to raters located at one or more central rating sites such that the raters are trained to apply substantially similar criteria in determining whether a candidate is a qualified subject for the clinical trial and/or in the actual assessment, or information collection, phase of the clinical trail. By having centralized, consistently trained raters that are independent of clinical trial investigators, inter-rater reliability is enhanced and potential bias is reduced, thus increasing the effectiveness of the clinical trial results by providing more qualified subjects and more accurate results. | 04-22-2010 |
20110071853 | SYSTEM AND METHOD FOR FACILITATING CENTRALIZED CANDIDATE SELECTION AND MONITORING SUBJECT PARTICIPATION IN CLINICAL TRIAL STUDIES - A system and method of facilitating centralized and standardized remote ratings of subjects in clinical trial studies includes providing training to raters located at one or more central rating sites such that the raters are trained to apply substantially similar criteria in determining whether a candidate is a qualified subject for the clinical trial and/or in the actual assessment, or information collection, phase of the clinical trail. By having centralized, consistently trained raters that are independent of clinical trial investigators, inter-rater reliability is enhanced and potential bias is reduced, thus increasing the effectiveness of the clinical trial results by providing more qualified subjects and more accurate results. | 03-24-2011 |
20110077962 | SYSTEM AND METHOD FOR FACILITATING CENTRALIZED CANDIDATE SELECTION AND MONITORING SUBJECT PARTICIPATION IN CLINICAL TRIAL STUDIES - A system and method of facilitating centralized and standardized remote ratings of subjects in clinical trial studies includes providing training to raters located at one or more central rating sites such that the raters are trained to apply substantially similar criteria in determining whether a candidate is a qualified subject for the clinical trial and/or in the actual assessment, or information collection, phase of the clinical trail. By having centralized, consistently trained raters that are independent of clinical trial investigators, inter-rater reliability is enhanced and potential bias is reduced, thus increasing the effectiveness of the clinical trial results by providing more qualified subjects and more accurate results. | 03-31-2011 |
20110282692 | SYSTEM AND METHOD FOR FACILITATING CENTRALIZED CANDIDATE SELECTION AND MONITORING SUBJECT PARTICIPATION IN CLINICAL TRIAL STUDIES - A system and method of facilitating centralized and standardized remote ratings of subjects in clinical trial studies includes providing training to raters located at one or more central rating sites such that the raters are trained to apply substantially similar criteria in determining whether a candidate is a qualified subject for the clinical trial and/or in the actual assessment, or information collection, phase of the clinical trail. By having centralized, consistently trained raters that are independent of clinical trial investigators, inter-rater reliability is enhanced and potential bias is reduced, thus increasing the effectiveness of the clinical trial results by providing more qualified subjects and more accurate results. | 11-17-2011 |