Downham, GB
David Downham, Hexton GB
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20100163572 | Beverage Dispenser - There is disclosed a beverage dispenser in which a cooled pre-mixed carbonated beverage, or a carbonated beverage component such as soda water, is dispensed through a delivery valve ( | 07-01-2010 |
Robert Downham, Cambridge GB
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20110065697 | 2-OXY-BENZOXAZINONE DERIVATIVES FOR THE TREATMENT OF OBESITY - The use of a compound comprising formula (I): | 03-17-2011 |
Robert Downham, Suffolk GB
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20090325925 | Thiophenes and uses thereof - This invention provides thiophene compounds of formula I: | 12-31-2009 |
20110009390 | 2-OXO-2- (2-PHENYL-5,6,7,8-TETRAHYDRO-INDOLIZIN-3-YL) -ACETAMIDE DERIVATIVES AND RELATED COMPOUNDS AS ANTIFUNGAL AGENTS - The invention provides compounds of formula (I), and pharmaceutically and agriculturally acceptable salts thereof: wherein: R1, R2, R3, R4, R5, R6, R7, R8, A1, L1 and n are as defined herein. These compounds and their pharmaceutically acceptable salts are useful in the manufacture of medicaments for use in the prevention or treatment of a fungal disease. Compounds of formula (I), and agriculturally acceptable salts thereof, may also be used as agricultural fungicides. | 01-13-2011 |
Robert Downham, Newmarket GB
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20100210617 | Aryl-Alkylamines And Heteroaryl-Alkylamines As Protein Kinase Inhibitors - The invention provides a compound of the formula (II): or a salt, solvate, tautomer or N-oxide thereof; wherein n is 0 or 1; one of Y | 08-19-2010 |
20100286167 | DIHYDROXYPHENYL ISOINDOLYLMETHANONES - This invention provides methods for treating cancer, particularly hematopoietic tumors of lymphoid or myeloid lineage, prostate cancer, lung cancer, gastrointestinal stromal tumor, breast cancer and melanoma, which comprise administering to the mammal a compound, salt, hydrate, tautomer or N-oxide according to formula (I): | 11-11-2010 |
20110144080 | PYRAZOLE DERIVATIVES AS PROTEIN KINASE MODULATORS - The invention provides compounds of the formula: (I) having protein kinase B inhibiting activity: wherein A is a saturated hydrocarbon linker group containing from 1 to 7 carbon atoms, the linker group having a maximum chain length of 5 atoms extending between R | 06-16-2011 |
20130005702 | PYRAZOLE DERIVATIVES AS PROTEIN KINASE MODULATORS - The invention provides compounds of the formula (I) having protein kinase B inhibiting activity: | 01-03-2013 |
20140271662 | PYRAZOLE DERIVATIVES AS PROTEIN KINASE MODULATORS - The invention provides compounds of the formula (I) having protein kinase B inhibiting activity: | 09-18-2014 |
Robert Downham, Manchester GB
Patent application number | Description | Published |
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20090215772 | Hydroxybenzamide derivatives and their use as inhibitors of HSP90 - The invention provides compounds of the formula (I): | 08-27-2009 |
20100056511 | 2- [ (2-SUBSTITUTED) -IND0LIZIN-3-YL] -2-OXO-ACETAMIDE DERIVATIVES AS ANTIFUNGAL AGENTS - The invention provides compounds of formula (I), and pharmaceutically acceptable salts thereof wherein: R1, R2, R3, R4, R5, R6, R7, X and X | 03-04-2010 |
20110152285 | PYRROLE ANTIFUNGAL AGENTS - The invention provides compounds of formula (I), and pharmaceutically and agriculturally acceptable salts thereof; wherein: R1, R2, R3, R4, R5, R6, A1, L1 and n are as defined herein. These compounds and their pharmaceutically acceptable salts are useful in prevention or treatment of a fungal disease. Compounds of formula (I), and agriculturally acceptable salts thereof, may also be used as agricultural fungicides. | 06-23-2011 |
Stephen Edward Downham, Worthing GB
Patent application number | Description | Published |
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20130294957 | Pump - A pump comprises a rotor arrangement and a stator arrangement. The stator arrangement comprises a first part made from a corrosive resistant material which defines a volume which in use is swept by the rotor arrangement for pumping fluid from an inlet to an outlet of the stator arrangement. A second part of the stator arrangement is made from a thermally conductive material which envelopes the first part so that heat generated in the first part can be transferred to the second part at the interface surface between the two parts. The second part has formed therein at least one duct | 11-07-2013 |