Bahrami
Ali Bahrami, Sammamish, WA US
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20080313162 | METHODS AND SYSTEMS FOR CONTEXT BASED QUERY FORMULATION AND INFORMATION RETRIEVAL - A method for context-based query formulation and information retrieval and aggregation is described. The method includes modeling one or more workflow activities utilized to perform work tasks, preparing at least one meta-querying template, to generate queries that utilize the modeled workflow activities, retrieving information relevant to the work task as determined utilizing the at least one meta-querying template, and aggregating the retrieved information for presentation to the user. | 12-18-2008 |
20100262451 | Simplified Approach for Service Composition and Orchestration - The different advantageous embodiments provide a method, apparatus, and computer program product for improved workflow management. A workflow model is executed. The workflow model may include a number of worklets. Each worklet in the number of worklets may have a number of associated assistlets. A determination is made as to whether a number of associated assistelets for a first worklet in the number of worklets execute during execution of the workflow model. In response to a determination that the number of associated assistlets for the first worklet execute, the number of associated assistlets for the first worklet are executed. | 10-14-2010 |
20130346141 | WORKFLOW MODELING WITH WORKETS AND TRANSITIONS - A computer is used to generate an approximation of a workflow in terms of worklets and transitions. Each worklet represents a phase of work in the workflow. Each transition indicates conditions for completion of a worklet. Each worklet includes at least one assistlet having executable code that will be executed for approximating of its work phase. | 12-26-2013 |
20140149436 | System and Method of Reduction of Irrelevant Information during Search - A system including a context-entity factory configured to build a data model defining an ontology of data objects that are context-aware, the model further defining metadata tags for the data objects. The system further includes a storage device storing the data objects as stored data objects, the device further storing associated contexts for corresponding ones of the stored objects. The system further includes a reduction component configured to capture a current context value of a first data object defined in the ontology, the component further configured to compare the current context value of the first data object with stored values of the associated contexts, and wherein when the current context value does not match a particular stored value of a particular associated context, the component is further configured to remove a corresponding particular stored data object and the particular associated context from the stored data objects. | 05-29-2014 |
20150324472 | System and Method of Reduction of Irrelevant Information During Search - A system including a context-entity factory configured to build a data model defining an ontology of data objects that are context-aware, the model further defining metadata tags for the data objects. The system further includes a storage device storing the data objects as stored data objects, the device further storing associated contexts for corresponding ones of the stored objects. The system further includes a reduction component configured to capture a current context value of a first data object defined in the ontology, the component further configured to compare the current context value of the first data object with stored values of the associated contexts, and wherein when the current context value does not match a particular stored value of a particular associated context, the component is further configured to remove a corresponding particular stored data object and the particular associated context from the stored data objects. | 11-12-2015 |
Ali Bahrami, Boulder, CO US
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20110113409 | SYMBOL CAPABILITIES SUPPORT WITHIN ELF - Systems and methods for efficient compilation and execution of program code. A compiler generates a plurality of families of object files, wherein each family comprises a set of system capabilities different from a set of another family. A link-editor receives the object files and stores a symbol capabilities table in a symbol capabilities section of an object file with a new file format. A symbol is associated with one or more instances, wherein each instance is associated with a different set of capabilities. In various embodiments, system capabilities may include a particular operating system, special-function additional instructions, or otherwise. Subsequent to creation of the single object file with multiple instances of a given function, a runtime linker chooses a given instance based on the capabilities of the platform on which the code is to be executed. | 05-12-2011 |
Gholamreza Bahrami, Kermanshah IR
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20140256673 | HERBAL EXTRACT COMPOSITION FOR THE TREATMENT OF DIABETES AND A METHOD OF EXTRACTING THE SAME - The embodiments herein provide a method for isolation and purification of a novel oligosaccharide molecule from the fruits of | 09-11-2014 |
Hamed Bahrami, Isfahan IR
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20090242783 | Non-Radioactive Electron Capture Detector for GC - Electron capture detector for use with an effluent stream from a gas chromatograph includes a non-radioactive electron source means and an adjacent ionization chamber in which electron capture take place. The detector comprises two partial chambers, of which one contains the electron source, and the other contains connections for input and output of analysis gas as well as a collector electrode for detecting ions. The collector electrode and the electron source are each of cylindrical configurations, and are coaxially aligned but are spaced apart with respect to each other. The electron current to the collector electrode provides an indication of the presence of electronegative constituents in the gas passing into the second partial chamber. | 10-01-2009 |
Hassan Bahrami, Lexington, KY US
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20090166944 | Duplex Architecture For An Imaging Apparatus - An imaging apparatus including an image transfer device, a first motor, a redrive section and a duplexing section. The first motor is drivingly connected to the image transfer device. The reversible redrive section is downstream from the image transfer device, and the reversible redrive section includes a second motor. The duplexing section includes a third motor. The duplexing section is positioned to receive media from the redrive section. The first motor, the second motor and the third motor are each independently controlled. | 07-02-2009 |
Kavan Saffa Bahrami, Portland, OR US
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20130173713 | SECURING COMMUNICATIONS AMONG FRIENDS WITH USER-WEARABLE MEMENTOS - Systems and methods for securing communication between users possessing user-wearable mementos are provided. One example computing system includes a data subsystem holding instructions executable by a processing subsystem. The example instructions are configured to assign a set identifier to a set of user-wearable mementos set that uniquely distinguishes the set from any other set and to encode the set identifier within a design for the set in response to receipt of a request to obtain the set. The instructions are also configured to provide access to a user communication interface in response to an access request for a set profile associated with the set, the access request including the set identifier as obtained from a particular user-wearable memento bearing the design. | 07-04-2013 |
Mehdi Bahrami, Vancouver CA
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20100236664 | APPARATUS AND METHODS FOR CONTROLLED DEBARKING OF WOOD - An apparatus for determining one or more optimal operating parameters for debarking wood is provided. The apparatus has a scraper and an actuator configured to adjust the position of the scraper toward a sample portion of the wood to scrape a surface of the sample portion of the wood with a scraping force. The apparatus also has a force sensor operatively associated with the scraper for detecting the scraping force. A light source impinges light on a scraped surface of the sample portion. A light detector detects a light image defined by light from the light source reflected by the scraped surface. A controller is operatively associated with the force sensor and the light detector. The controller has processing means to determine the one or more optimal operating parameters based on signals relating to the scraping force and signals relating to the light image. The one or more optimal operating parameters are relevant to debarking wood proximal to the sample portion. | 09-23-2010 |
20150104563 | DEVICE AND METHOD FOR VERIFYING THE CONSTRUCTION OF ADHESIVELY-ATTACHED SUBSTRATES - A device and method for inspecting the deposition of hot melt onto an object to be assembled. A comparison is made between sensed images of the object after application of the hot melt and a predetermined standard to determine if the construction integrity of the object made with the hot melt is within the range established by the standard. Composite images from a sensor operating in the infrared band and another sensor reveal physical features of the object, as well as provide registration information about the placement of the hot melt on the assembled object. Composite images also present a way to visually ascertain ongoing or past production operations in order to trace problems with the raw material used for the object, as well as for the construction process of the object with the hot melt. | 04-16-2015 |
Mohammad Eghtesadi Bahrami, Crawley GB
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20150275902 | VACUUM PUMP - The present invention relates to a vacuum pump | 10-01-2015 |
20150292515 | VACUUM PUMP WITH BACK-UP BEARNG CONTACT SENSOR - The present invention relates to a vacuum pump | 10-15-2015 |
Morteza Bahrami, St. Albans GB
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20130278931 | SAMPLE RECEIVING APPARATUS - Sample receiving apparatus ( | 10-24-2013 |
Naghmeh Bahrami, Tehran IR
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20140356410 | BIODEGRADABLE AND BIOCOMPATIBLE NANO COMPOSITE T-PLATE IMPLANT AND A METHOD OF SYNTHESIZING THE SAME - The embodiments herein provide a biodegradable and biocompatible T-plate nano-composite implant with stem cells for treating and repairing broken bones, damaged tissues and torn ligaments. The implant comprises a polymeric matrix part comprising poly lactic glycolic acids (PLGA), a bioceramic part comprising hydroxyapatite (HAp) nanoparticles and an endometrial stem cell. The PLGA and HAp nanoparticles act as a matrix and reinforcing agents respectively. A method is provided for synthesizing the T-plate implant. The method comprises synthesizing hydroxyapatite (HAp) nanoparticles, poly lactic glycolic acids (PLGA) and HAp nano composite implant. The casting of the poly lactic glycolic acids (PLGA) and HAp nano composite are done in a mold to obtain a T-plate nano composite. An endometrial stem cell from an epithelial cell lining from uterus is isolated and cultured. The endometrial stem cells are implanted on the nano-composite implant. | 12-04-2014 |
20140370515 | METHOD OF CO-CULTURING HUMAN ENDOMETRIAL STEM CELLS AND RAT EMBRYONIC TOOTH BUD CELLS TO OBTAIN AMELOBLAST CELLS - The various embodiments herein provide a method of co-culturing human endometrial stem cells and rat embryonic tooth bud cells to obtain ameloblast cells. The human endometrial stem cells are isolated from human females between the ages of 18-40 and cultured. The hEnSCs are identified using flowcytometry. The rat embryonic tooth bud cells are isolated from rat embryos and cultured. After the hEnSCs and rat embryonic tooth bud cells reach a desired level of cell growth, the hEnSCs are transferred to culture plate inserts and the rat embryonic tooth bud cells are transferred to a culture plate. The hEnSCs and rat embryonic tooth bud cells are co-cultured to obtain ameloblast cells. Immunocytochemical analysis is used to characterize the differentiated ameloblast cells. Quantitative real time PCR (qRT-PCR) is used to detect the presence of Ameloblastin, Amelogenin, Amelotin and Cytokeratin 14 proteins in differentiated ameloblast cells. | 12-18-2014 |
Nima Bahrami, Rancho Palos Verdes, CA US
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20150046297 | INTERACTIVE DISPLAY SYSTEM FOR FOOD AND ENTERTAINMENT RETAIL ESTABLISHMENTS - The present disclosure describes an interactive menu display system providing retail establishments with a flexible electronic menu display that enables presentation of a large number of menu items by incorporating, among other things, a menu-item scrolling feature. The display system can be configured to subdivide a display system to include fields, such as physical portions of a display unit, or individual display units, that are designated for predetermined categories of menu items, and within those fields, the menu items may be sequentially displayed, such as in a scrolling, paging, or other step-wise fashion. The display system can also include a menu configuration user interface designed for the owner or manager of the retail establishment to conveniently and efficiently update menu content, layout, and other configuration settings. The display system can be configured to update the menu display in real-time based on updates to menu content and settings. | 02-12-2015 |
20150081478 | INTERACTIVE DISPLAY SYSTEM FOR FOOD AND ENTERTAINMENT RETAIL ESTABLISHMENTS - The present disclosure describes an interactive menu display system providing retail establishments with a flexible electronic menu display that enables presentation of a large number of menu items by incorporating, among other things, a menu-item scrolling feature. The display system can be configured to subdivide a display system to include fields, such as physical portions of a display unit, or individual display units, that are designated for predetermined categories of menu items, and within those fields, the menu items may be sequentially displayed, such as in a scrolling, paging, or other step-wise fashion. The display system can also include a menu configuration user interface designed for the owner or manager of the retail establishment to conveniently and efficiently update menu content, layout, and other configuration settings. The display system can be configured to update the menu display in real-time based on updates to menu content and settings. | 03-19-2015 |
Paul Bahrami, New Hall, CA US
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20120193259 | METHOD AND APPARATUS FOR LABELED TOILETRIES - One embodiment of a unique method of enabling hotels to provide visually impaired patrons the ability to use all toiletries typically found in a hotel bathroom is envisioned. Said method involves supplying a hotel with an assortment of all toiletries the hotel would need to fully stock their bathrooms in a visually impaired toiletry kit. Such a visually impaired toiletry kit would ensure that all hotel guests benefit equally from complementary conditioners, shampoos and other accompaniments supplied as a courtesy by the hotel. | 08-02-2012 |
20130313147 | METHOD AND APPARATUS FOR LABELED TOILETRIES - One embodiment of a unique method of enabling visually impaired consumers the ability to identify the contents of a particular toiletry bottle without having to open the container. Said method involves supplying the consumer with a specially designed toiletry bottle comprising both visually and tactilely readable indicia. Said indicia would inform both the visually impaired and all others capable of reading the indicia, what the contents of the container are without having to open said container. | 11-28-2013 |
S. Bahram Bahrami, Emeryville, CA US
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20080279780 | Fluorescent chlorotoxin conjugate and method for intra-operative visualization of cancer - A chlorotoxin conjugate detectable by fluorescence imaging that allows for intra-operative visualization of cancerous tissues, compositions that include the chlorotoxin conjugate, and methods for using the chlorotoxin conjugate. | 11-13-2008 |
20100330589 | NEEDLE ARRAY ASSEMBLY AND METHOD FOR DELIVERING THERAPEUTIC AGENTS - A fluid delivery device includes an array of needles, each in fluid communication with a respective reservoir. Respective actuators are coupled so as to be operable to drive fluid from the reservoirs via needle ports. Each needle can have a plurality of ports, and the ports can be arranged to deliver a substantially equal amount of fluid at any given location along its length. A driver is coupled to the actuators to selectively control the rate, volume, and direction of flow of fluid through the needles. The device can simultaneously deliver a plurality of fluid agents along respective axes in solid tissue in vivo. If thereafter resected, the tissue can be sectioned for evaluation of an effect of each agent on the tissue, and based on the evaluation, candidate agents selected or deselected for clinical trials or therapy, and subjects selected or deselected for clinical trials or therapeutic treatment. | 12-30-2010 |
20110230839 | Needle Array Assembly and Method for Delivering Therapeutic Agents - A fluid delivery device includes an array of needles, each in fluid communication with a respective reservoir. Respective actuators are coupled so as to be operable to drive fluid from the reservoirs via needle ports. Each needle can have a plurality of ports, and the ports can be arranged to deliver a substantially equal amount of fluid at any given location along its length. A driver is coupled to the actuators to selectively control the rate, volume, and direction of flow of fluid through the needles. The device can simultaneously deliver a plurality of fluid agents along respective axes in solid tissue in vivo. If thereafter resected, the tissue can be sectioned for evaluation of an effect of each agent on the tissue, and based on the evaluation, candidate agents selected or deselected for clinical trials or therapy, and subjects selected or deselected for clinical trials or therapeutic treatment. | 09-22-2011 |
20120087866 | NEEDLE ARRAY ASSEMBLY AND METHOD FOR DELIVERING THERAPEUTIC AGENTS - A fluid delivery device includes an array of needles, each in fluid communication with a respective reservoir. Respective actuators are coupled so as to be operable to drive fluid from the reservoirs via needle ports. Each needle can have a plurality of ports, and the ports can be arranged to deliver a substantially equal amount of fluid at any given location along its length. A driver is coupled to the actuators to selectively control the rate, volume, and direction of flow of fluid through the needles. The device can simultaneously deliver a plurality of fluid agents along respective axes in solid tissue in vivo. If thereafter resected, the tissue can be sectioned for evaluation of an effect of each agent on the tissue, and based on the evaluation, candidate agents selected or deselected for clinical trials or therapy, and subjects selected or deselected for clinical trials or therapeutic treatment. | 04-12-2012 |
20120089095 | NEEDLE ARRAY ASSEMBLY AND METHOD FOR DELIVERING THERAPEUTIC AGENTS - A fluid delivery device includes an array of needles, each in fluid communication with a respective reservoir. Respective actuators are coupled so as to be operable to drive fluid from the reservoirs via needle ports. Each needle can have a plurality of ports, and the ports can be arranged to deliver a substantially equal amount of fluid at any given location along its length. A driver is coupled to the actuators to selectively control the rate, volume, and direction of flow of fluid through the needles. The device can simultaneously deliver a plurality of fluid agents along respective axes in solid tissue in vivo. If thereafter resected, the tissue can be sectioned for evaluation of an effect of each agent on the tissue, and based on the evaluation, candidate agents selected or deselected for clinical trials or therapy, and subjects selected or deselected for clinical trials or therapeutic treatment. | 04-12-2012 |
20120094866 | NEEDLE ARRAY ASSEMBLY AND METHOD FOR DELIVERING THERAPEUTIC AGENTS - A fluid delivery device includes an array of needles, each in fluid communication with a respective reservoir. Respective actuators are coupled so as to be operable to drive fluid from the reservoirs via needle ports. Each needle can have a plurality of ports, and the ports can be arranged to deliver a substantially equal amount of fluid at any given location along its length. A driver is coupled to the actuators to selectively control the rate, volume, and direction of flow of fluid through the needles. The device can simultaneously deliver a plurality of fluid agents along respective axes in solid tissue in vivo. If thereafter resected, the tissue can be sectioned for evaluation of an effect of each agent on the tissue, and based on the evaluation, candidate agents selected or deselected for clinical trials or therapy, and subjects selected or deselected for clinical trials or therapeutic treatment. | 04-19-2012 |
20120109104 | NEEDLE ARRAY ASSEMBLY AND METHOD FOR DELIVERING THERAPEUTIC AGENTS - A fluid delivery device includes an array of needles, each in fluid communication with a respective reservoir. Respective actuators are coupled so as to be operable to drive fluid from the reservoirs via needle ports. Each needle can have a plurality of ports, and the ports can be arranged to deliver a substantially equal amount of fluid at any given location along its length. A driver is coupled to the actuators to selectively control the rate, volume, and direction of flow of fluid through the needles. The device can simultaneously deliver a plurality of fluid agents along respective axes in solid tissue in vivo. If thereafter resected, the tissue can be sectioned for evaluation of an effect of each agent on the tissue, and based on the evaluation, candidate agents selected or deselected for clinical trials or therapy, and subjects selected or deselected for clinical trials or therapeutic treatment. | 05-03-2012 |
20120121514 | NEEDLE ARRAY ASSEMBLY AND METHOD FOR DELIVERING THERAPEUTIC AGENTS - A fluid delivery device includes an array of needles, each in fluid communication with a respective reservoir. Respective actuators are coupled so as to be operable to drive fluid from the reservoirs via needle ports. Each needle can have a plurality of ports, and the ports can be arranged to deliver a substantially equal amount of fluid at any given location along its length. A driver is coupled to the actuators to selectively control the rate, volume, and direction of flow of fluid through the needles. The device can simultaneously deliver a plurality of fluid agents along respective axes in solid tissue in vivo. If thereafter resected, the tissue can be sectioned for evaluation of an effect of each agent on the tissue, and based on the evaluation, candidate agents selected or deselected for clinical trials or therapy, and subjects selected or deselected for clinical trials or therapeutic treatment. | 05-17-2012 |
20120265064 | NEEDLE ARRAY ASSEMBLY AND METHOD FOR DELIVERING THERAPEUTIC AGENTS - A fluid delivery device includes an array of needles, each in fluid communication with a respective reservoir. Respective actuators are coupled so as to be operable to drive fluid from the reservoirs via needle ports. Each needle can have a plurality of ports, and the ports can be arranged to deliver a substantially equal amount of fluid at any given location along its length. A driver is coupled to the actuators to selectively control the rate, volume, and direction of flow of liquid through the needles. The device can simultaneously deliver a plurality of fluid agents along respective axes in solid tissue in vivo. If thereafter resected, the tissue can be sectioned for evaluation of an effect of each agent on the tissue, and based on the evaluation, candidate agents selected or deselected for clinical trials or therapy, and subjects selected or deselected for clinical trials or therapeutic treatment. | 10-18-2012 |
20120296206 | NEEDLE ARRAY ASSEMBLY AND METHOD FOR DELIVERING THERAPEUTIC AGENTS - A fluid delivery device includes an array of needles, each in fluid communication with a respective reservoir. Respective actuators are coupled so as to be operable to drive fluid from the reservoirs via needle ports. Each needle can have a plurality of ports, and the ports can be arranged to deliver a substantially equal amount of fluid at any given location along its length. A driver is coupled to the actuators to selectively control the rate, volume, and direction of flow of liquid through the needles. The device can simultaneously deliver a plurality of fluid agents along respective axes in solid tissue in vivo. If thereafter resected, the tissue can be sectioned for evaluation of an effect of each agent on the tissue, and based on the evaluation, candidate agents selected or deselected for clinical trials or therapy, and subjects selected or deselected for clinical trials or therapeutic treatment. | 11-22-2012 |
20140162360 | NEEDLE ARRAY ASSEMBLY AND METHOD FOR DELIVERING THERAPEUTIC AGENTS - A fluid delivery device includes an array of needles, each in fluid communication with a respective reservoir. Respective actuators are coupled so as to be operable to drive fluid from the reservoirs via needle ports. Each needle can have a plurality of ports, and the ports can be arranged to deliver a substantially equal amount of fluid at any given location along its length. A driver is coupled to the actuators to selectively control the rate, volume, and direction of flow of fluid through the needles. The device can simultaneously deliver a plurality of fluid agents along respective axes in solid tissue in vivo. If thereafter resected, the tissue can be sectioned for evaluation of an effect of each agent on the tissue, and based on the evaluation, candidate agents selected or deselected for clinical trials or therapy, and subjects selected or deselected for clinical trials or therapeutic treatment. | 06-12-2014 |
20140162901 | NEEDLE ARRAY ASSEMBLY AND METHOD FOR DELIVERING THERAPEUTIC AGENTS - A fluid delivery device includes an array of needles, each in fluid communication with a respective reservoir. Respective actuators are coupled so as to be operable to drive fluid from the reservoirs via needle ports. Each needle can have a plurality of ports, and the ports can be arranged to deliver a substantially equal amount of fluid at any given location along its length. A driver is coupled to the actuators to selectively control the rate, volume, and direction of flow of fluid through the needles. The device can simultaneously deliver a plurality of fluid agents along respective axes in solid tissue in vivo. If thereafter resected, the tissue can be sectioned for evaluation of an effect of each agent on the tissue, and based on the evaluation, candidate agents selected or deselected for clinical trials or therapy, and subjects selected or deselected for clinical trials or therapeutic treatment. | 06-12-2014 |
20140241993 | FLUORESCENT CHLOROTOXIN CONJUGATE AND METHOD FOR INTRA-OPERATIVE VISUALIZATION OF CANCER - A chlorotoxin conjugate detectable by fluorescence imaging that allows for intra-operative visualization of cancerous tissues, compositions that include the chlorotoxin conjugate, and methods for using the chlorotoxin conjugate. | 08-28-2014 |
20140309590 | NEEDLE ARRAY ASSEMBLY AND METHOD FOR DELIVERING THERAPEUTIC AGENTS - A fluid delivery device includes an array of needles, each in fluid communication with a respective reservoir. Respective actuators are coupled so as to be operable to drive fluid from the reservoirs via needle ports. Each needle can have a plurality of ports, and the ports can be arranged to deliver a substantially equal amount of fluid at any given location along its length. A driver is coupled to the actuators to selectively control the rate, volume, and direction of flow of fluid through the needles. The device can simultaneously deliver a plurality of fluid agents along respective axes in solid tissue in vivo. If thereafter resected, the tissue can be sectioned for evaluation of an effect of each agent on the tissue, and based on the evaluation, candidate agents selected or deselected for clinical trials or therapy, and subjects selected or deselected for clinical trials or therapeutic treatment. | 10-16-2014 |
Seyed Bahram Bahrami, Emeryville, CA US
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20130259807 | CELL CULTURE SCREEN FOR AGENTS THAT CONTROL ADIPOGENESIS AND MYOFIBROBLAST DIFFERENTIATION - Methods are provided for the rapid and robust screening test agents for adipogenic activity. Agents testing positive in the assays are good candidate agents for wrinkle reduction, normalizing skin appearance after reconstructive or cosmetic surgery, e.g., grafted tissue on burn victims, normalizing skin appearance during and after wound healing, and the like. In certain embodiments the methods involve providing mammalian test cells with adipogenic potential wherein said cells are primed for, but withheld from differentiation into adipocytes; contacting the cells with the test agent(s); and screening said test cells for an adipocyte phenotype wherein the presence of a feature characteristic of an adipocyte is an indicator that said test agent is adipogenic. | 10-03-2013 |
20140179616 | PEPTIDES THAT STIMULATE SUBCUTANEOUS ADIPOGENESIS - Peptides of 5 to 14 amino acids in length that stimulate subcutaneous adipogenesis and uses thereof are provided. | 06-26-2014 |
20150284433 | PEPTIDES THAT STIMULATE SUBCUTANEOUS ADIPOGENESIS - Peptides of 5 to 14 amino acids in length that stimulate subcutaneous adipogenesis in mammals and uses thereof are provided. | 10-08-2015 |
Shervin Bahrami, Artius C DK
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20130108653 | BIVALENT MOLECULES FOR HIV ENTRY INHIBITION | 05-02-2013 |
Shervin Bahrami, Arhus C DK
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20110305749 | HIV-1 Envelope Polypeptides for HIV Vaccine - Immunogenic HIV-1 envelope polypeptides are provided, wherein specific amino acid residues are mutated to repress immunosuppression in GP41, thereby boosting the immune response against HIV-1. Specifically, mutation of those specific residues does not affect the fusogenic properties of the viral particle and/or the overall protein structure of the viral envelope protein. The invention further provides peptides and antigens based on the immunogenic HIV-1 envelopes as well as nucleic acid sequences and vectors encoding those. Moreover, biological entities such as viral particles are provided, as well as use of the provided components for preparation of a vaccine against HIV-1/AIDS. | 12-15-2011 |
Shervin Bahrami, Aarhus C DK
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20090324553 | Chimeric Viral Envelopes - The invention relates to chimeric polytropic viral envelope polypeptides and uses thereof, as well as to polynucleotides encoding said chimeric polypeptides and constructs comprising said polypeptides and/or polynucleotides. The invention also relates to chimeric retroviral envelope polypeptides, polynucleotides and vectors encoding said chimeric retroviral envelope polypeptides, virus particles and cells harbouring said chimeric envelope polypeptides. Said chimeric polypeptide comprise an envelope polypeptide, or fragment thereof, and a polypeptide sequence of a receptor binding region, ligand or polypeptide sequence of a ligand binding region, and optionally a linker sequence. The invention include methods of targeting receptors, methods of treatment and methods for delivery of agents using said chimeric retroviral envelope polypeptides. The invention is applicable for directed targeting and controlled fusion of virus particles with other cellular membranes. | 12-31-2009 |
20140335117 | Identification and Attenuation of the Immunosuppressive Domains in Fusion Proteins of Enveloped RNA Viruses - The present invention relates to enveloped RNA viruses. The invention in particular relates to the generation of superior antigens for mounting an immune response by first identifying then mutating the immunosuppressive domains in fusion proteins of enveloped RNA viruses resulting in decreased immunosuppressive properties of viral envelope proteins from the viruses. | 11-13-2014 |
20150299702 | CIRCULAR RNA FOR INHIBITION OF MICRORNA - The present invention relates to inhibition of microRNAs (miRNA), other types of RNA and RNA-binding proteins. In particular the present invention relates to nucleic acid sequences that are circular and allow inhibition of the interactions between microRNAs and their RNA target and being resistant to degradation by exonucleases. Also, the present invention relates to nucleic acid sequence that are circular and acts as an RNA blocker or protein decoy. | 10-22-2015 |
Siavosh Bahrami, San Francisco, CA US
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20150350148 | HEALTHCARE SECURE MESSAGING AND REMINDER SYSTEM - A system provides secure messaging of healthcare data and prompts message responses using prioritized hierarchical reminders. Messages can be sent and received through an application executing on a mobile device or on a web browser or application executing on any computer. The system can provide message notifications and multiple reminders to ensure that a user is reliably receiving and also reading messages. If an in-application message is not read within a time period, the message can followed by a reminder message informing the recipient that there is a secure message waiting. The reminder message can be sent using an application notification or through other channels, such as by SMS text message, automated voice telephone call, or e-mail, without including sensitive patient healthcare information. | 12-03-2015 |
Soheyl Bahrami, Gotzendorf AT
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20120094314 | DIAGNOSIS OF SEPTIC COMPLICATIONS - The invention describes a method for diagnosing of septic complications in polytraumatised human or animal patients, said patients being free of traumatic brain injury, by determining the level of the C-type natriuretic peptide (CNP), its precursors or fragments thereof, especially the precursor of the C-type natriuretic peptide (NT-proCNP), in this patient and diagnosing the patient a having septic complications or being at risk of developing septic complications, if the level of CNP, its precursors or fragments thereof, especially NT-proCNP, is increased compared to normal levels. | 04-19-2012 |
Taraneh Bahrami, San Jose, CA US
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20110154079 | Instruction For Enabling A Procesor Wait State - In one embodiment, the present invention includes a processor having a core with decode logic to decode an instruction prescribing an identification of a location to be monitored and a timer value, and a timer coupled to the decode logic to perform a count with respect to the timer value. The processor may further include a power management unit coupled to the core to determine a type of a low power state based at least in part on the timer value and cause the processor to enter the low power state responsive to the determination. Other embodiments are described and claimed. | 06-23-2011 |
20130185580 | INSTRUCTION FOR ENABLING A PROCESOR WAIT STATE - In one embodiment, the present invention includes a processor having a core with decode logic to decode an instruction prescribing an identification of a location to be monitored and a timer value, and a timer coupled to the decode logic to perform a count with respect to the timer value. The processor may further include a power management unit coupled to the core to determine a type of a low power state based at least in part on the timer value and cause the processor to enter the low power state responsive to the determination. Other embodiments are described and claimed. | 07-18-2013 |
20130246824 | Instruction For Enabling A Processor Wait State - In one embodiment, the present invention includes a processor having a core with decode logic to decode an instruction prescribing an identification of a location to be monitored and a timer value, and a timer coupled to the decode logic to perform a count with respect to the timer value. The processor may further include a power management unit coupled to the core to determine a type of a low power state based at least in part on the timer value and cause the processor to enter the low power state responsive to the determination. Other embodiments are described and claimed. | 09-19-2013 |
Whoman Bahrami, Washington, DC US
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20130049347 | APPARATUS FOR VIEWING PAGES - The present invention includes a pageprop device including a retaining wall, a base and, in some embodiments stabilizing tab, which can be used by a user to view a page of bound material in a “hands free” manner. In addition, the angle between the beginning portion of the retaining wall and the beginning portion of the base is selected to ensure that sufficient light is displayed on the page of the bound material that is of interest to the user. Rectangular wedges are used to fix this angle. | 02-28-2013 |