Bayley
Antony Mw Bayley, Wootton Baasett GB
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20080240450 | Systems and methods for logging acoustic incidents - Systems and methods for logging acoustic incidents. An exemplary system includes a transducer configured to receive an electrical signal from an electrical signal source and produce a corresponding acoustic signal, a recording system operable to record the electrical signal from the electrical signal source, and an incident estimation and control system coupled to the recording system to estimate an acoustic incident and to instruct the recording system to record the electrical signal that is producing the acoustic incident. The system can replay the recorded electrical signal through the same transducer that was in use at the time of the acoustic incident, to exactly reproduce the sound that occurred. | 10-02-2008 |
Antony M.w. Bayley, Wootton Bassett GB
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20100046767 | Wireless Headset Noise Exposure Dosimeter - Systems and methods for measuring noise exposure associated with use of a wireless headset are presented. In one example, a transition from a wireless headset standby mode operation to a wireless headset active mode operation is identified. A stored noise dose measurement at the wireless headset is recalled, and a current noise dose measurement is calculated at the wireless headset for a duration of the active mode operation. A transition from the wireless headset active mode operation to the wireless headset standby mode operation is identified, and an updated noise dose measurement is recorded at the wireless headset. | 02-25-2010 |
Antony M.w. Bayley, Royal Wootton Bassett GB
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20140365214 | Character Data Entry - Methods and apparatuses for entry of character data are disclosed. In one example, a user action is received at a headset input user interface. The user action is correlated to a character data previously stored. The character data is transmitted to a host device, the character data configured to be automatically entered in one or more data fields. | 12-11-2014 |
Frederick John Bayley, Sea Ford GB
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20090313997 | Unitary engine and energy accumulation system - A unitary, hybrid engine which includes an internal combustion engine which is used both for locomotive and heat generation externally of the cylinders of the combustion engine, wherein the generated heat is employed in conjunction with an evaporator to generate steam, which is then stored in an energy accumulator which retains the stored energy by way of a pressured water containment unit. The pressurized water containment unit accretes the energy and, upon attainment of a predetermined pressure and liquid level, the steam is transmitted to one or more of the cylinders of the unitary engine to provide the motive power to the unitary engine. The engine includes control systems to permit the sole use of steam during such times as may be required for environmental or pollution control requirements. | 12-24-2009 |
Hagan Bayley, Kidlington GB
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20110177498 | BASE-DETECTING PORE - The invention relates to a mutant α-hemolysin (α-HL) pore which is useful for detecting one or more nucleotides by stochastic sensing. The pore is particularly useful for sequencing DNA or RNA. A molecular adaptor that allows detection of the nucleotide(s) is covalently attached to the pore. The pore is specifically modified to facilitate positioning of the adaptor and may be modified to facilitate covalent attachment. | 07-21-2011 |
Hagan Bayley, Oxford GB
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20080311582 | Methods Using Pores - The invention relates to a method of identifying an individual nucleotide, comprising (a) contacting the nucleotide with a transmembrane protein pore so that the nucleotide interacts with the pore and (b) measuring the current passing through the pore during the interaction and thereby determining the identity of the nucleotide. The invention also relates to a method of sequencing nucleic acid sequences and kits related thereto. | 12-18-2008 |
20110229877 | ENZYME-PORE CONSTRUCTS - The invention relates to constructs comprising a transmembrane protein pore subunit and a nucleic acid handling enzyme. The pore subunit is covalently attached to the enzyme such that both the subunit and enzyme retain their activity. The constructs can be used to generate transmembrane protein pores having a nucleic acid handling enzyme attached thereto. Such pores are particularly useful for sequencing nucleic acids. The enzyme handles the nucleic acid in such a way that the pore can detect its component nucleotides by stochastic sensing. | 09-22-2011 |
20120219960 | METHODS USING PORES - The invention relates to a method of identifying an individual nucleotide, comprising (a) contacting the nucleotide with a transmembrane protein pore so that the nucleotide interacts with the pore and (b) measuring the current passing through the pore during the interaction and thereby determining the identity of the nucleotide. The invention also relates to a method of sequencing nucleic acid sequences and kits related thereto. | 08-30-2012 |
20140296180 | CYCLIC OLIGOSACCHARIDES FOR USE IN THE TREATMENT AND PREVENTION OF BACTERIAL INFECTION - Compounds which inhibit Wza-mcdiated polysaccharide transport are useful in the prevention or treatment of bacterial infection, in particular of | 10-02-2014 |
Jeff Bayley, Midhurst CA
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20130272791 | MOISTURE RESPONSIVE IRRIGATION METHOD AND APPARATUS - An irrigation device comprising a moisture responsive barrier is provided. At least a portion of the barrier has perforations, at least some of the perforations are associated with a water swellable material. The perforations are configured to open as the water swellable material loses moisture and dries out and are configured to close as said water swellable material is exposed to and absorbs water, such as during a watering step. According to another aspect the irrigation method includes the steps of positioning a perforated barrier between a source of irrigation water and an area to be irrigated, wherein the perforations are associated with a water swellable material; exposing the water swellable material to water to cause the water swellable material to swell to close the perforations; and permitting the water swellable material to dry, to open the perforations, whereby the opening and closing of the perforations regulates the amount of irrigation water being applied across the barrier in the irrigation method. | 10-17-2013 |
Jeffrey D. Bayley, Midhurst CA
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20140166595 | REPLACEABLE GREASE TRAP SYSTEM FOR A WASTEWATER SYSTEM AND METHOD OF USING THE SAME - The present invention relates to a grease trap system for wastewater systems, having an inlet pipe with a shut off valve, an outlet pipe with a shut off valve and a grease interceptor comprising a replaceable container body including means to trap fats, oils and grease within the body. The body has inlet and outlet slide couplers in opposed walls, and each coupler has an associated connecting means to sealingly fluidly connect the slide couplers to the inlet and outlet pipes. When the container body is disconnected from the pipes the slide couplers may also be sealed by a removable plug for transport. The slide couplers displace inwardly and outwardly relative to the container to give clearance between the pipes to remove the container. A method of replacing full containers with empty containers is also comprehended. | 06-19-2014 |
John Hagan Bayley, Oxford GB
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20100297638 | MOLECULAR ADAPTORS - The invention relates to transmembrane protein pore for use in detecting a analyte in a sample. The pore comprises a molecular adaptor that facilitates an interaction between the pore and the analyte. The adaptor is covalently attached to the pore in an orientation that allows the analyte to be detected using the pore. | 11-25-2010 |
John Hagan Pryce Bayley, Oxford Oxfordshire GB
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20140356289 | Multisomes: Encapsulated Droplet Networks - The invention provides a droplet encapsulate comprising: a drop of a hydrophobic medium; a peripheral layer of non-polymeric amphipathic molecules around the surface of the drop; and an aqueous droplet within the peripheral layer, the aqueous droplet comprising: (a) an aqueous medium and (b) an outer layer of non-polymeric amphipathic molecules around the surface of the aqueous medium. The invention also provides processes for preparing the droplet encapsulates. Various uses of the droplet encapsulates are also described, including their use as drug delivery vehicles, in synthetic biology, and in the study of membrane proteins. | 12-04-2014 |
John Hagan Pryce Bayley, Oxford GB
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20110311965 | METHODS OF ENHANCING TRANSLOCATION OF CHARGED ANALYTES THROUGH TRANSMEMBRANE PROTEIN PORES - The invention relates to enhancing translocation of a charged analyte through a transmembrane protein pore. Translocation is enhanced by increasing the net opposing charge of the barrel or channel and/or entrance of the pore. The invention also relates to pores enhanced in accordance with the invention. | 12-22-2011 |
20120107802 | METHOD FOR SEQUENCING A HETEROPOLYMERIC TARGET NUCLEIC ACID SEQUENCE - The invention relates to a method for sequencing a heteropolymeric target nucleic acid sequence that involves stochastic sensing. The invention also relates to a method for improving a pore for sequencing a target nucleic acid sequence by modifying one or more sites in the pore. | 05-03-2012 |
20140001056 | METHOD USING FLUORINATED AMPHIPHILES | 01-02-2014 |
20140051069 | ENZYME-PORE CONSTRUCTS - The invention relates to constructs comprising a transmembrane protein pore subunit and a nucleic acid handling enzyme. The pore subunit is covalently attached to the enzyme such that both the subunit and enzyme retain their activity. The constructs can be used to generate transmembrane protein pores having a nucleic acid handling enzyme attached thereto. Such pores are particularly useful for sequencing nucleic acids. The enzyme handles the nucleic acid in such a way that the pore can detect its component nucleotides by stochastic sensing. | 02-20-2014 |
20150031020 | ENZYME-PORE CONSTRUCTS - The invention relates to constructs comprising a transmembrane protein pore subunit and a nucleic acid handling enzyme. The pore subunit is covalently attached to the enzyme such that both the subunit and enzyme retain their activity. The constructs can be used to generate transmembrane protein pores having a nucleic acid handling enzyme attached thereto. Such pores are particularly useful for sequencing nucleic acids. The enzyme handles the nucleic acid in such a way that the pore can detect its component nucleotides by stochastic sensing. | 01-29-2015 |
John Hagen Pryce Bayley, Oxford GB
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20100032627 | FORMATION OF BILAYERS OF AMPHIPATHIC MOLECULES - A method of forming bilayers of amphipathic molecules uses droplets of aqueous solution in a hydrophobic medium such as oil. A layer of amphipathic molecules such as a lipid is formed around the surfaces of the droplets. This may be achieved by providing the lipid in the oil and leaving the droplets for a time sufficient to form the layer. The droplets are brought into contact with one another so that a bilayer of the amphipathic molecules is formed as an interface between the contacting droplets. The bilayers may be used for a wide range of studies. The technique has numerous advantages including providing a long lifetime for the bilayers, allowing study of small volumes and allowing the construction of chains and networks of droplets with bilayers in between to study complex systems. | 02-11-2010 |
20130146815 | FORMATION OF BILAYERS OF AMPHIPATHIC MOLECULES - A method of forming bilayers of amphipathic molecules uses droplets of aqueous solution in a hydrophobic medium such as oil. A layer of amphipathic molecules such as a lipid is formed around the surfaces of the droplets. This may be achieved by providing the lipid in the oil and leaving the droplets for a time sufficient to form the layer. The droplets are brought into contact with one another so that a bilayer of the amphipathic molecules is formed as an interface between the contacting droplets. The bilayers may be used for a wide range of studies. The technique has numerous advantages including providing a long lifetime for the bilayers, allowing study of small volumes and allowing the construction of chains and networks of droplets with bilayers in between to study complex systems. | 06-13-2013 |
Nicholas Bayley, Derby GB
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20110182751 | ROTOR DISC - A rotor disc | 07-28-2011 |
Paul Andrew Bayley, Cambridge GB
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20090322794 | DISPLAY WITH IMPROVED UNIFORMITY - An image display is disclosed comprising an image display device with a light emitting surface having an array of picture elements; a light guide formed from a plurality of light transmission guides with the input to each light transmission guide being provided by a sub-array of a plurality of picture elements from the light emitting surface of the image display device and luminance correction means to assign a colour component value and a dither fraction value to each sub-array of a plurality of picture elements on the light emitting surface of the image display device. Assigning a colour component value ( | 12-31-2009 |
Richard Peter Bayley, Maidenhead GB
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20110277675 | FLOATABLE DRY DOCKS - A floating dock including a submersible platform including at least one buoyancy tank wherein the buoyancy tank has a plurality of compartments each of which has a permanently open vent through which water is freely flowable into and out of the compartment and an inlet which enables air to be expelled from the compartment into the atmosphere or enables compressed air to be supplied to the compartment via a non return valve which causes water within the tank to be forced out via the vent, thereby increasing the buoyancy of the tank. The vent does not have any valves associated with it and is permanently open to the sea. As a result the floating dry dock of the present invention may be lowered and raised faster than conventional dry docks which rely on valved vents to control entry and exit of water into and out of their buoyancy tanks. | 11-17-2011 |
Steven Paul Bayley, Macclesfield GB
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20130334108 | CENTRIFUGAL SIFTING APPARATUS - A stationary screen ( | 12-19-2013 |