Kaluza, DE
Brigitte Kaluza, Weilheim DE
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20150232560 | METHOD FOR THE SELECTION AND PRODUCTION OF TAILOR-MADE, SELECTIVE AND MULTI-SPECIFIC THERAPEUTIC MOLECULES COMPRISING AT LEAST TWO DIFFERENT TARGETING ENTITIES AND USES THEREOF - Herein is reported a method for determining a combination of antigen binding sites comprising the steps of (i) determining the binding specificity and/or affinity and/or effector function and/or in vivo half-life of a multitude of bispecific antibodies prepared by combining each member of a first multitude of antibody Fab fragments or scFv antibody fragments with each member of a second multitude of antibody Fab fragments or scFv antibody fragments, and a linker comprising at one of its termini the second member of the first binding pair and at the respective other terminus the second member of the second binding pair, whereby the first multitude specifically binds to a first cell surface molecule and the second multitude specifically binds to a second cell surface molecule, and (ii) choosing the bispecific antibody with suitable binding specificity and/or affinity and/or effector function and/or in vivo half-life and thereby determining a combination of antigen binding sites. | 08-20-2015 |
Georg Kaluza, Lauf DE
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20090320660 | METHOD FOR PRODUCING AT LEAST ONE WINDOW OPENING IN AN ELONGATE PAPER SUBSTRATE, AND APPARATUS - The invention concerns a method of and an apparatus for producing at least one window opening ( | 12-31-2009 |
Heinrich Kaluza, Erfurt DE
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20110163640 | Rotor cooling for a dynamoelectric machine - A rotor for a dynamoelectric machine is disclosed. A bottom duct is disposed in the rotor, through which a cooling medium flows and conductors are cooled via radial ducts during operation. The bottom duct is embodied such that the cross section thereof decreases towards the center of the rotor. | 07-07-2011 |
Horst Kaluza, Ludwigshafen DE
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20140158626 | WATER-ABSORBING COMPOSITES - This invention relates to a process for producing water-absorbing composites comprising the steps of foaming an aqueous mixture comprising at least one monoethylenically unsaturated monomer bearing acid groups, at least one crosslinker, at least one initiator and at least one surfactant, contacting the foam obtained with at least one web of synthetic fibers and polymerizing, to the composites themselves and to their use for absorbing aqueous fluids. | 06-12-2014 |
Horst Jurgen Kaluza, Ludwigshafen DE
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20160000961 | FEMININE HYGIENE ABSORBENT ARTICLES COMPRISING WATER-ABSORBING COMPOSITES - This invention relates to a feminine hygiene absorbent article comprising water-absorbing composites obtainable by foaming an aqueous mixture comprising at least one monoethylenically unsaturated monomer bearing acid groups, at least one crosslinker, at least one initiator and at least one surfactant, contacting the foam obtained with at least one web of synthetic fibers and polymerizing, to the composites themselves and to their use for absorbing aqueous fluids. | 01-07-2016 |
Horst Jürgen Kaluza, Ludwigshafen DE
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20120296296 | FEMININE HYGIENE ABSORBENT ARTICLES COMPRISING WATER-ABSORBING COMPOSITES - This invention relates to a feminine hygiene absorbent article comprising water-absorbing composites obtainable by foaming an aqueous mixture comprising at least one monoethylenically unsaturated monomer bearing acid groups, at least one crosslinker, at least one initiator and at least one surfactant, contacting the foam obtained with at least one web of synthetic fibers and polymerizing, to the composites themselves and to their use for absorbing aqueous fluids. | 11-22-2012 |
Jan Kaluza, Boeblingen DE
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20100106300 | DEVICE FOR CONTROLLING AN ELECTROMAGNETIC VALVE - In a device for controlling an electromagnetic valve, input device(s) write a multitude of measured values for the current and/or the voltage into a first memory to represent a characteristic. Analysis device(s) perform a state analysis and/or a change-over-time analysis. On the basis of the state analysis and/or the change-over-time analysis, evaluation device(s) correct at least one control variable, which characterizes the control, and write it into a second memory. Control device(s) control an output stage on the basis of the control variables. | 04-29-2010 |
20100134120 | PROCEDURE FOR CHECKING THE FUNCTIONALITY OF AN ELECTRIC HEATING DEVICE - A procedure for checking the functionality of an electric heating device ( | 06-03-2010 |
20100326186 | FILL LEVEL DETECTION APPARATUS - A fill level detection apparatus ( | 12-30-2010 |
20110120559 | Device and method for controlling an electromagnetic valve - In a method for controlling an electromagnetic valve, the temperature of the valve is detected, and activation of and/or the current feed to the valve are performed as a function of the temperature of the valve. | 05-26-2011 |
Jens Kaluza, Bonn DE
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20150229608 | METHOD FOR CONFIGURING NETWORK NODES OF A TELECOMMUNICATIONS NETWORK, TELECOMMUNICATIONS NETWORK, PROGRAM AND COMPUTER PROGRAM PRODUCT - A method for configuring network nodes of a telecommunications network includes configuring a remote network node of a plurality of remote network nodes based on a first set of configuration parameters; authenticating the remote network node based on an encryption information obtained from an encryption information infrastructure; configuring a firewall entity of a plurality of firewall entities based on a second set of configuration parameters, wherein the configuration of the firewall entity is initiated by the remote network node based on an initial configuration message being sent directly or indirectly from the remote network node to the firewall entity; and authenticating the configuration of the firewall entity based on the encryption information of the remote network node, the encryption information being obtained by the firewall entity directly or indirectly from the remote network node with the initial configuration message. | 08-13-2015 |
Klaus Kaluza, Weilheim DE
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20120213774 | Antibodies against human IL33R and uses thereof - An antibody binding to IL33R characterized in that the heavy chain variable domain comprises a CDR3 region of SEQ ID NO:1, a CDR2 region of SEQ ID NO:2 and a CDR1 region of SEQ ID NO:3 and in that the light chain variable domain comprises a CDR3 region of SEQ ID NO:4, a CDR2 region of SEQ ID NO:5 and a CDR1 region of SEQ ID NO:6 or a chimeric, humanized or T cell epitope depleted antibody variant thereof has advantageous properties for the treatment of inflammatory diseases. | 08-23-2012 |
20120329997 | ANTIBODIES AGAINST HUMAN CSF-1R AND USES THEREOF - The present invention relates to antibodies against human CSF-1R (CSF-1R antibody), methods for their production, pharmaceutical compositions containing said antibodies, and uses thereof. | 12-27-2012 |
20130005949 | ANTIBODIES AGAINST HUMAN CSF-1R AND USES THEREOF - The present invention relates to antibodies against human CSF-1R (CSF-1R antibody), methods for their production, pharmaceutical compositions containing said antibodies, and uses thereof. | 01-03-2013 |
20140065707 | ANTIBODIES AGAINST HUMAN ANGIOPOIETIN 2 - The present invention relates to antibodies against human Angiopoietin 2 (anti-ANG-2 antibodies), methods for their production, pharmaceutical compositions containing said antibodies, and uses thereof. | 03-06-2014 |
20140302015 | ANTIBODIES AGAINST HUMAN IL33R AND USES THEREOF - An antibody binding to IL33R characterized in that the heavy chain variable domain comprises a CDR3 region of SEQ ID NO:1, a CDR2 region of SEQ ID NO:2 and a CDR1 region of SEQ ID NO:3 and in that the light chain variable domain comprises a CDR3 region of SEQ ID NO:4, a CDR2 region of SEQ ID NO:5 and a CDR1 region of SEQ ID NO:6 or a a chimeric, humanized or T cell epitope depleted antibody variant thereof has advantageous properties for the treatment of inflammatory diseases. | 10-09-2014 |
20140336363 | ANTIBODIES AGAINST HUMAN CSF-1R AND USES THEREOF - The present invention relates to antibodies against human CSF-1R (CSF-1R antibody), methods for their production, pharmaceutical compositions containing said antibodies, and uses thereof. | 11-13-2014 |
20150140003 | ANTI-alpha-SYNUCLEIN ANTIBODIES AND METHODS OF USE - The invention provides anti-human alpha-synuclein antibodies and methods of using the same. | 05-21-2015 |
20150175696 | ANTIBODIES AGAINST HUMAN CSF-1R AND USES THEREOF - The present invention relates to antibodies against human CSF-1R (CSF-1R antibody), methods for their production, pharmaceutical compositions containing said antibodies, and uses thereof. | 06-25-2015 |
20150284457 | ANTIBODIES AGAINST HUMAN ANGIOPOIETIN 2 - The present invention relates to antibodies against human Angiopoietin 2 (anti-ANG-2 antibodies), methods for their production, pharmaceutical compositions containing said antibodies, and uses thereof. | 10-08-2015 |
Klaus Kaluza, Bad Heilbrunn DE
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20100159587 | ANTIBODIES AGAINST HUMAN ANGIOPOIETIN 2 - The present invention relates to antibodies against human Angiopoietin 2 (anti-ANG-2 antibodies), methods for their production, pharmaceutical compositions containing said antibodies, and uses thereof. | 06-24-2010 |
20100168181 | BENZIMIDAZOLE AMIDO DERIVATIVES, THEIR MANUFACTURE AND USE AS PHARMACEUTICAL AGENTS - Objects of the present invention are the compounds of formula (I) their pharmaceutically acceptable salts, enantiomeric forms, diastereoisomers and racemates, the preparation of the above-mentioned compounds, medicaments containing them and their manufacture, as well as the use of the above-mentioned compounds in the control or prevention of illnesses such as cancer. | 07-01-2010 |
20110165156 | ANTIBODIES AGAINST HUMAN CSF-1R AND USES THEREOF - The present invention relates to antibodies against human CSF-1R (anti-CSF-1R antibody), methods for their production, pharmaceutical compositions containing said antibodies, and uses thereof. | 07-07-2011 |
20110218199 | PYRIDONEAMIDE DERIVATIVES, THEIR MANUFACTURE AND USE AS PHARMACEUTICAL AGENTS - Compounds of formula I | 09-08-2011 |
20120141500 | Antibodies Against Human Angiopoietin 2 - The present invention relates to antibodies against human Angiopoietin 2 (anti-ANG-2 antibodies), methods for their production, pharmaceutical compositions containing said antibodies, and uses thereof. | 06-07-2012 |
20120142091 | Antibodies Against Human Angiopoietin 2 - The present invention relates to antibodies against human Angiopoietin 2 (anti-ANG-2 antibodies), methods for their production, pharmaceutical compositions containing said antibodies, and uses thereof. | 06-07-2012 |
20120156198 | Antibodies against IL-18R1 and uses thereof - The invention provides anti-IL-18R1 antibodies and methods of using the same. | 06-21-2012 |
20130156789 | ANTIBODIES AGAINST HUMAN ANGIOPOIETIN 2 - The present invention relates to a method of treating a disease or disorder in a patient comprising administering, to a patient in need of such treatment, an antibody which binds specifically to human angiopoietin-2 (ANG-2), wherein said antibody comprises: | 06-20-2013 |
20140065151 | ANTIBODIES AGAINST HUMAN ANGIOPOIETIN 2 - The present invention relates to a method of treating a disease or disorder in a patient comprising administering, to a patient in need of such treatment, an antibody which binds specifically to human angiopoietin-2 (ANG-2). The present invention also relates to a method for preventing metastasis in a patient suffering from primary cancer comprising administering, to a patient in need of such preventative treatment, an antibody which binds specifically to human angiopoietin-2 (ANG-2). | 03-06-2014 |
20150158950 | ANTIBODIES AGAINST HUMAN CSF-1R AND USES THEREOF - The present invention relates to antibodies against human CSF-1R (anti-CSF-1R antibody), methods for their production, pharmaceutical compositions containing said antibodies, and uses thereof. | 06-11-2015 |
20150274830 | ANTIBODIES AGAINST HUMAN CSF-1R AND USES THEREOF - The present invention relates to antibodies against human CSF-1R (anti-CSF-1R antibody), methods for their production, pharmaceutical compositions containing said antibodies, and uses thereof. | 10-01-2015 |
20150274831 | ANTIBODIES AGAINST HUMAN CSF-1R AND USES THEREOF - The present invention relates to antibodies against human CSF-1R (anti-CSF-1R antibody), methods for their production, pharmaceutical compositions containing said antibodies, and uses thereof. | 10-01-2015 |
Klaus Kaluza, Weilhelm DE
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20150080556 | ANTIBODIES AGAINST HUMAN CSF-1R AND USES THEREOF - The present invention relates to antibodies against human CSF-1R (CSF-1R antibody), methods for their production, pharmaceutical compositions containing said antibodies, and uses thereof. | 03-19-2015 |
Mirko Kaluza, Jena DE
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20090275875 | EXTRACORPOREAL CIRCULATION SYSTEM, ESPECIALLY FOR A MULTIFUNCTIONAL HEART-LUNG BYPASS AND FOR THE MINIMIZATION OF AIR EMBOLISMS - The task was to create a multifunctional system for the extracorporeal circulation (ECC) for a heart-lung bypass, which primarily makes use of the advantages of a minimized ECC system, but which in the case of need at any time can also be used universally and at low risk as another closed and open ECC system. Besides, it shall provide the option of an automatic negative pressure and volume compensation when being used as minimized ECC system. | 11-05-2009 |
Nora Kaluza, Heidelberg DE
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20150290337 | DIAGNOSIS, PREVENTION AND TREATMENT OF DISEASES OF THE JOINT - The present invention relates to apolymeric prodrug for use in the treatment, prevention and/or diagnosis a disease of the joint and pharmaceutical compositions and medical devices comprising said polymeric prodrugs. | 10-15-2015 |
Olaf Kaluza, Herten DE
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20150355652 | FIELD DEVICE WITH A SWITCHING CONVERTER CIRCUIT - A field device ( | 12-10-2015 |
Peter Kaluza, Rieden DE
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20100007335 | Measuring Apparatus - A measuring apparatus, in particular for measuring current, is provided. In at least one embodiment, the measuring apparatus includes a sensor and an evaluation device which is coupled or can be coupled thereto, in which the coupling is effected contactlessly, in particular by way of a transponder interface. As such, on the one hand current can be measured in a reaction-free manner, wherein on the other hand the resulting measuring apparatus can be used in a particularly flexible and versatile manner on account of the maneuverability of the components with respect to one another and on account of the relatively large possible distance between the two parts of the transponder interface. | 01-14-2010 |
Roland Kaluza, Langen DE
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20090120331 | Apparatus for shaking stacks of sheet material - An apparatus for shaking stacks of sheet material includes a base frame with a table movably mounted thereon for vibratory motion. A rear stop is positioned along a rear portion of the table. First and second lateral stops are positioned along a side portion of the table. The first lateral stop is disposed adjacent the rear stop to contact the adjacent edges of the sheet material stack when the table is vibrated and is inclined toward the rear and first stops. The second stop is movable between a stop position and a non-stop position. The table includes a main table portion and a movable table portion disposed along a forward portion of the table that shifts between a support position and a non-support position for the sheet material stack. | 05-14-2009 |
Sebastian Kaluza, Muenchen DE
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20110040817 | CIRCUIT AND METHOD FOR GENERATING A TRUE, CIRCUIT-SPECIFIC AND TIME-INVARIANT RANDOM NUMBER - The invention relates to a circuit for generating a true, circuit-specific and time-invariant random binary number, having: a matrix of K−L delay elements that can be connected to each other by means of L−1 single or double commutation circuits into chains of delay elements of length L, a single or double demultiplexer connected before the matrix, a single or double multiplexer connection after the matrix, and a run time or number comparator, wherein the setting of the commutation circuits, the demultiplexer, and the multiplexer can be prescribed by a control signal, wherein the circuit comprises a channel code encoder whereby code words of a channel code can be generated and a transcriber, whereby code words of the channel code can be transcribed into the control signal of the L−1 single or double commutation circuits, and a method for generating a true, circuit-specific and time-invariant random number by means of a matrix of L−K delay elements, L−1 single or double commutation circuits, a single or double demultiplexer connected before the matrix, a single or double multiplexer connection after the matrix, and a run time or number comparator, comprising at least the steps a) generating a code word of a channel code, b) transcribing a code word of a channel code to a selection code, c) generating chains of L delay elements by setting a setting corresponding to the code word of the selection code for the L−1 single or double commutation circuits, the single or double demultiplexer, and the single or double multiplexer, d) pairwise comparing of two variables determined by the delay times of two chains defined by the setting of the L−1 commutation circuits corresponding to the code word of the channel code, by means of a number or delay comparator for generating a bit of the true, circuit-specific and time-invariant random number. | 02-17-2011 |