Patent application number | Description | Published |
20100278796 | Method for Improving the Digestibility and the Assimilability of Cereals and/or Fibres in a Monogastric Herbivorous Animal - The invention relates to a method for improving the digestibility and assimilability of fibres and/or cereals in a monogastric herbivorous animal comprising the step of administering to said monogastric herbivorous animal an effective amount of at least one strain of bacterium selected fromselected from the group consisting of strains of bacteria of the genera | 11-04-2010 |
20110274781 | Method for Producing Cured Milk to Feed Milk-Fed Animals - The invention relates to a method for producing cured milk for feeding milk-fed animals, particularly livestock. | 11-10-2011 |
20120142531 | Coated Dehydrated Microorganisms with Enhanced Stability and Viability - The present invention relates to coated dehydrated microorganisms comprising a dehydrated microorganism surrounded by at least one coating, said coating comprising by dry weight at least 25% of hygroscopic salt(s) and wherein the pH of the coating is compatible with viability of the coated dehydrated microorganism. The coating can be partially crystalline, the salt(s) in the coating having preferably a crystallinity degree of up to 60% once applied onto the dehydrated microorganism. The present invention also relates to liquid coating compositions, methods for coating and protecting a dehydrated microorganism. Finally, the present invention relates to a method for the preparation of food products, feed products, consumer healthcare products or agri-products as well as to a food product, feed product, a consumer healthcare product or an agri-product containing such coated dehydrated microorgansims. | 06-07-2012 |
20140112889 | METHOD FOR REDUCING METHANE PRODUCTION IN A RUMINANT ANIMAL - A method for reducing methane production in a ruminant animal comprising the step of administering to said ruminant animal an effective amount of at least one strain of bacterium of the genus | 04-24-2014 |
20140349850 | Coated Dehydrated Microorganisms with Enhanced Stability and Viability - The present invention relates to coated dehydrated microorganisms comprising a dehydrated microorganism surrounded by at least one coating, said coating comprising by dry weight at least 25% of hygroscopic salt(s) and wherein the pH of the coating is compatible with viability of the coated dehydrated microorganism. The coating can be partially crystalline, the salt(s) in the coating having preferably a crystallinity degree of up to 60% once applied onto the dehydrated microorganism. The present invention also relates to liquid coating compositions, methods for coating and protecting a dehydrated microorganism. Finally, the present invention relates to a method for the preparation of food products, feed products, consumer healthcare products or agri-products as well as to a food product, feed product, a consumer healthcare product or an agri-product containing such coated dehydrated microorganisms. | 11-27-2014 |
Patent application number | Description | Published |
20130206298 | PNEUMATIC TIRE TREAD COMPRISING A PLURALITY OF INCISIONS - A tread comprises a central zone with a width of between 70% and 80% of the width W of the tread. The central zone comprises one or more circumferential bands, each being delimited by two grooves of a width greater than or equal to 2 mm, and each comprising a contact surface intended to come into contact with the ground and a plurality of transverse sipes distributed evenly in the circumferential direction. Each sipe has, on the contact surface, a width less than 2 mm so as to define a mean circumferential void ratio, which is between 0.5 times and 1.5 times the ratio between a mean thickness (E) of the circumferential band to a mean circumferential radius of curvature (Rc) of the said circumferential band. The sipes divide the circumferential band into a succession of blocks, each having two edge corners intersecting the contact surface of the circumferential band, at least one of the edge corners of said block extending radially by an inclined part forming a chamfer. This inclined part connects the edge corner to a lateral wall of the block so as to generate an offset in the circumferential direction between the said edge corner and the lateral wall of the block. | 08-15-2013 |
20150290981 | TIRE SIDEWALL MARKINGS REDUCING AERODYNAMIC DRAG - Tire for a passenger vehicle, including a crown portion on its exterior with a tread, extended laterally by sidewalls terminating in beads to contact with rim parts (J) on which the tire is mounted, each sidewall including an inner wall and an outer wall, at least one of the sidewalls includes a plurality of first sectors and second sectors, formed on the outer wall of a first sidewall portion between the crown portion the axially outermost points when this tire is mounted inflated, wherein the first sectors are completely without raised markings, i.e. raised markings of a height greater than 0.2 mm, whereas the second sectors are provided with raised markings, these raised markings having a height equal to at least 0.2 mm, wherein the first sectors each form an angle equal to at least 20°, and wherein the sum of the angles of said first sectors is equal to at least 120°. | 10-15-2015 |
Patent application number | Description | Published |
20110155293 | Directional Tire Tread with Modified Incisions - Directional tire tread having a rolling surface, this tread being provided with a plurality of incisions bounded by mutually opposing walls, each of said walls entering the rolling surface in such a way as to form an edge called the leading edge of an element of material, corresponding to the edge that enters the contact patch first, and an edge called the trailing edge of the same element of material, corresponding to the edge that enters the contact patch after the leading edge, each incision comprising at least one segment bounded by mutually opposing walls that make, with a direction perpendicular to the rolling surface passing through the intersection of the incision with the rolling surface, a negative average angle α whose absolute value is less than 55°, this tread being characterized in that this segment of negative angle α exits the rolling surface via an enlarged end portion bounded by mutually opposing first and second faces, the angles of the first face and second face being positive and not equal to each other. | 06-30-2011 |
20110290393 | Tire Tread Comprising Incisions Provided with Projections - Tread band for a tire comprising a plurality of elements in relief, each element in relief having a contact face and lateral faces, at least some of these elements in relief having at least one incision opening onto two of the said lateral faces, this incision being delimited by a first face and a second face, these first and second faces each comprising projections, each projection of the first face being arranged on the said face so that it can collaborate through contact with a first projection and a second projection on the second face opposite, the said first and second projections of the second face being situated one on each side of the projection of the first face in opposite directions D | 12-01-2011 |
20120006458 | Tire Tread Comprising Incisions and Recesses - Tire tread comprising a plurality of elements forming relief, each element comprising a contact face, a plurality of elements of the tread being provided with at least one incision, this incision opening onto the contact face in order to form second edges parallel with one another and with an average orientation at most equal to 45° with the direction of the axis of rotation of the tire provided with this tread, each incision also opening onto two lateral surfaces of the element so as to form strips having a length L and a width d, this width d being less than the length L, each strip comprising at least one cavity entirely contained in the strip and of which the largest dimension is oriented so as to be in the direction of the length of the strip inside which it is formed, each cavity having a length Lc, measured along its largest dimension, which is between 10% and 90% of the length L of the strip, the total of the lengths Lc of all the cavities of one and the same strip being more than 10% of the length L of the said strip. | 01-12-2012 |
20120298270 | TYRE TREAD HAVING CAVITIES AND INCISIONS - A tire tread having a plurality of ribs delimited by cut-outs, each having a generally parallelepipedal shape and having a length (L) and a width (W), the width (W) being determined between a first lateral face and a second lateral face of the rib, the width (W) being less than the length (L), at least one rib having at least one cavity placed inside the rib, the cavity extending mainly in the length (L) of the rib. The tread having an incision extending mainly in the length (L) of the rib, the incision emerging on the first lateral face of the rib and the incision emerging in the cavity while forming an opening, the length (Lo) of the opening determined in the length (L) of the rib corresponding at least to 80% of the length (Lc) of the cavity determined in the length (L) of the rib. | 11-29-2012 |
20120325388 | Tire Containing an Antioxidant Reservoir - A tire comprising: two beads intended to come into contact with a mounting rim; two sidewalls extending the beads radially outward, the two sidewalls joining in a crown comprising a crown reinforcement extending axially between two axial ends and surmounted by a tread; and a carcass reinforcement anchored in the two beads and extending through the sidewalls to the crown, wherein the crown includes, radially to the inside of the carcass reinforcement, at least one reservoir layer made of a rubber mix having a high antioxidant content, so that at least one reservoir layer is radially plumb with each axial end of the crown reinforcement, wherein said at least one reservoir layer has an antioxidant content equal to or greater than 5 phr but does not exceed 10 phr, and wherein said at least one reservoir layer further includes an oxygen absorbent. | 12-27-2012 |
Patent application number | Description | Published |
20090175871 | METHOD FOR DEMONSTRATING PRESENCE OR ABSENCE OF MARKERS ASSOCIATED WITH THE PRESENCE AND/OR THE CHEMOSENSITIVITY OF TUMORS - A method for detecting presence or absence of a tumor in a mammal and/or its sensitivity to chemotherapies, including, on a biological sample from said mammal, detecting and/or quantifying: presence of an eEF1A1 protein, and/or presence of antibodies directed against an eEF1A1 protein or a fragment including at least one epitope of eEF1a1 protein, and/or presence of a MARK3 protein, and/or presence of antibodies directed against a MARK3 protein or a fragment comprising at least one epitope of the MARK3 protein. | 07-09-2009 |
20090280523 | Method for determining the molecular composition of a target tissue or another body structure, and its diagnostic applications - The present invention relates to a sampling instrument adapted for taking a sample in situ and in vivo or taking a sample ex vivo of a target tissue or body structure, in a maximum quantity of less than 10 | 11-12-2009 |
20100076054 | SENSIZITATION OF CANCER CELLS TO THERAPY USING SINA TARGETING GENES FROM THE 1P AND 19Q CHROMOSOMAL REGIONS - The invention relates to the identification of genes involved in resistance of cancer cells to therapy, to short nucleic acid molecules which inhibit the expression of these genes by RNA interference and to their use as adjuvant in cancer therapy, to sensitize cancer cells to conventional anticancer agents; the short nucleic acid molecules are double-stranded short interfering nucleic acid molecules including a sense and an antisense region, wherein the sense region includes a nucleotide sequence that is selected from the group consisting of: the sequences SEQ ID NO: 15, 11, 13, 14, 30, 31, 38, 46, 64 and 70 and the sequences having at least 70% identity, preferably at least 80% identity, more preferably at least 90% identity with the sequences, and the antisense region includes a nucleotide sequence that is complementary to the sense region. | 03-25-2010 |
20120322680 | USE OF MIRNAS AS BIOMARKERS IN GLIOMA DIAGNOSIS - The present application relates to the use of miRNAs as biomarkers in glioma diagnosis. It also relates to the use of miRNAs as biomarkers in glioblastoma and oligodendroglioma diagnosis. | 12-20-2012 |
20130079663 | Device for Transiently Contacting At Least One Unit For Capturing Biological Targets With A Fluid Containing Them, Method For Recovering The Captured Targets And System For Contacting And Recovery - The invention relates to a device for transiently contacting at least one unit for capturing biological targets with a body fluid containing them, a method for recovering the captured targets for analysis, and a system for contacting and recovering a capture substrate included in said unit. The invention relates to samples obtained in particular in vivo from body fluids of the human body, e.g. circulating body fluids, said fluids possibly containing, as targets, proteins, oligonucleotides such as RNA or DNA, antibodies, enzymes or cells. A contacting device ( | 03-28-2013 |
20130330727 | INTRA-TISSUE IN VITRO DIAGNOSIS METHOD FOR DIAGNOSING BRAIN TUMOURS - An in vitro diagnostic method for diagnosing a brain tumour belonging to the group formed by two types of tumours: ODGs and GBMs, and for identifying the type of tumour, the method includes the measurement of at least two ratios of the expression levels of miRNA pairs extracted from a biological sample originating from a patient suspected of presenting one of the above-mentioned brain tumours. | 12-12-2013 |
20140377793 | Device And Method Of Sampling And Analysing Biological Or Biochemical Species - A method of sampling biological or biochemical species, comprising the following steps: a) arranging a capture surface (SC) for said biological or biochemical species in contact with a biological tissue or fluid (TB); and b) rinsing said surface to remove biological or biochemical species that have not been adsorbed; the method being characterised in that said capture surface is the surface of a nanoporous material (MC). A method of analysing said biological or biochemical species, characterised by the use of said surface as an analysis support. The analysis may in particular be performed using a method selected from mass spectroscopy with laser desorption and fluorescence imaging. A device for sampling biological or biochemical species comprising a rod (TM) to which is attached a material (MC) having a capture surface (SC) for said biological or biochemical species, arranged so as to be able to be brought into contact with a biological tissue or fluid (TB), characterised in that said material is a nanoporous material. The rod can be slid into a guide tube to facilitate the insertion thereof into a human or animal body. | 12-25-2014 |
20150182207 | DEVICE FOR SAMPLING A BIOLOGICAL TISSUE - The invention relates to a device ( | 07-02-2015 |
Patent application number | Description | Published |
20120149060 | Nucleic Acids for Cloning and Expressing Multiprotein Complexes - The present invention relates to a nucleic acid containing at least one homing endonuclease site (HE) and at least one restriction enzyme site (X) wherein the HE and X sites are selected such that HE and X result in compatible cohesive ends when cut by the homing endonuclease and restriction enzyme, respectively, and the ligation product of HE and X cohesive ends can neither be cleaved by the homing endonuclease nor by the restriction enzyme. Further subject-matter of the present invention relates to a vector comprising the nucleic acid of the present invention, host cells containing the nucleic acid and/or the vector, a kit for cloning and/or expression of multiprotein complexes making use of the vector and the host cells, a method for producing a vector containing multiple expression cassettes, and a method for producing multiprotein complexes. The invention also relates to a methods of assembling multiple single vectors (“vector entities”) into fusion vectors and to method of disassembling a fusion vector containing multiple of such vector entities into single vectors. The invention is also directed to fusion vectors containing multiple vector entities. | 06-14-2012 |
20140356960 | Nucleic acids for cloning and expressing multiprotein complexes - The present invention relates to a nucleic acid containing at least one homing endonuclease site (HE) and at least one restriction enzyme site (X) wherein the HE and X sites are selected such that HE and X result in compatible cohesive ends when cut by the homing endonuclease and restriction enzyme, respectively, and the ligation product of HE and X cohesive ends can neither be cleaved by the homing endonuclease nor by the restriction enzyme. Further subject-matter of the present invention relates to a vector comprising the nucleic acid of the present invention, host cells containing the nucleic acid and/or the vector; a kit for cloning and/or expression of multiprotein complexes making use of the vector and the host cells, a method for producing a vector containing multiple expression cassettes, and a method for producing multiprotein complexes. The invention also relates to a methods of assembling multiple single vectors (“vector entities”) into fusion vectors and to method of disassembling a fusion vector containing multiple of such vector entities into single vectors. The invention is also directed to fusion vectors containing multiple vector entities. | 12-04-2014 |
20150361403 | IMPROVED BACULOVIRAL EXPRESSION SYSTEM AND METHODS OF PRODUCING THE SAME - The present invention is based on the discovery that large parts of the genome of nucleopolyhedtovirus (NPV)-alpha baculovirus clade Ia viruses can be deleted with out deleterious effect on the usability of the virus comprising such genome in the infection of cells in cell culture. Accordingly, the present invention provides NPY-alpha baculovirus clade Ia genome which is reduced in size in comparison to the respective native NPV-alpha baculovirus clade Ia genome, such genomes comprising heterologous nucleotides, viruses comprising either of these genomes, cells infected with such viruses and methods for producing such viruses and cells. | 12-17-2015 |
Patent application number | Description | Published |
20090042179 | Fluorescence Reflection Imaging Device with Two Wavelengths - A first light source has a first wavelength corresponding to an excitation wavelength of a fluorophore. The excitation wavelength and an emission wavelength of the fluorophore delineate a predetermined interval. A second light source has a second wavelength offset with respect to the first wavelength so as to be outside said predetermined interval. The offset between the first and second wavelengths is comprised between 30 nm and 100 nm. A camera comprises a filter opaque to the first and second wavelengths and transparent to the emission wavelength and to wavelengths substantially higher than the higher of the first and second wavelengths. The light sources and camera are synchronized to alternately activate one of the light sources and make the camera alternately acquire a fluorescence image and a background noise image. | 02-12-2009 |
20090152474 | Fluorescent Imaging Device Comprising a Two-Wavelength Variable Lighting Power Light Source - A fluorescence imaging device comprises a light source with two wavelengths and variable lighting power. The light source is in the form of a ring and it comprises an alternation of first and second zones respectively able to emit first and second light radiations respectively having distinct first and second wavelengths. Each of the zones further comprises a plurality of elementary light sources controllable independently by selective lighting control means of said elementary sources. | 06-18-2009 |
20090262365 | OPTICAL DEVICE FOR ANALYZING A SCATTERING MEDIUM HELD BY A SUPPORT - An optical device intended for the analysis of a scattering medium, including at least one light source distant from the scattering medium and capable of providing an incident light beam intended to illuminate the scattering medium; at least one sensor capable of detecting a radiation emitted by the scattering medium; a support of the scattering medium at least partially non-absorbing for the incident light beam and the scattered radiation. All or part of the support is formed of a scattering material having a decreased scattering coefficient greater than 0.1 cm | 10-22-2009 |
20110190639 | Bi-Spectral Peroperative Optical Probe - Optical probes for medical applications are provided. The probe is devised so as to be able to be held in one hand. A basic version of the probe includes: a first excitation lighting source suitable for causing a fluorescence radiation of predetermined substances; a second visible lighting source, the first and the second source being devised so as to illuminate a common zone termed the intervention zone; a first photosensitive matrix sensor; and a second photosensitive matrix sensor. The first and second photosensitive matrix sensors are devised in such a way that, when the optical probe is arranged a predetermined distance from the intervention zone, the image in the visible spectrum of the said zone is formed on the photosensitive surface of the first matrix sensor and the image in the fluorescence spectrum of the said zone is formed on the photosensitive surface of the second sensor. A first variant of the probe includes only a single optical objective, a second variant only a single photosensitive matrix sensor, and a third variant makes it possible to work under polarized light. | 08-04-2011 |
20130236059 | FLUORESCENCE REFLECTION IMAGING DEVICE WITH TWO WAVELENGTHS - A first light source has a first wavelength corresponding to an excitation wavelength of a fluorophore. The excitation wavelength and an emission wavelength of the fluorophore delineate a predetermined interval. A second light source has a second wavelength offset with respect to the first wavelength so as to be outside said predetermined interval. The offset between the first and second wavelengths is comprised between 30 nm and 100 nm. A camera comprises a filter opaque to the first and second wavelengths and transparent to the emission wavelength and to wavelengths substantially higher than the higher of the first and second wavelengths. The light sources and camera are synchronized to alternately activate one of the light sources and make the camera alternately acquire a fluorescence image and a background noise image. | 09-12-2013 |
20150241634 | DOUBLE-FLUX LIGHTING DEVICE INCLUDING MULTIPLE OPTICAL FIBRES, AND ASSOCIATED PEROPERATIVE PROBE - In the field of lighting devices comprising two fiber sources of light and a light transport comprising a plurality of second multimode optical fibers, such devices are designed to be installed in intra-operative optical probes requiring a perfectly uniform visible illumination and fluorescence illumination. A lighting device is provided which comprises a single lens disposed between the fiber sources and the input of the light transport and an optical diffuser. A lighting device is also provided which comprises an afocal system disposed between the fiber sources and the input of the light transport and an optical diffuser. An optical fiber coupler or a semi-reflecting plate provides the mixing of the two fiber sources. | 08-27-2015 |
Patent application number | Description | Published |
20110256142 | NOVEL METHODS AND ANTIBODIES FOR TREATING CANCER - The invention relates to novel methods for the treatment of tumors, comprising administration of a bispecific antibody or a combination of two or more non-cross-blocking antibodies that recognize the same target antigen or antigenic complex. In particular, the invention relates to a method for inducing complement-mediated cell killing in the treatment of a tumor, said method comprising combined administration, to a human being in need thereof, of a first antibody and a second antibody, wherein—said first antibody binds EGFR, —said second antibody binds EGFR, —said first and second antibody are non-cross-blocking, and—the dosage regimen is such that CDC is obtained at the tumor site. | 10-20-2011 |
20140348833 | NOVEL METHODS AND ANTIBODIES FOR TREATING CANCER - The invention relates to novel methods for the treatment of tumors, comprising administration of a bispecific antibody or a combination of two or more non-cross-blocking antibodies that recognize the same target antigen or antigenic complex. In particular, the invention relates to a method for inducing complement-mediated cell killing in the treatment of a tumor, said method comprising combined administration, to a human being in need thereof, of a first antibody and a second antibody, wherein
| 11-27-2014 |