Thomas, GB
Adele Thomas, Aberdeen GB
Patent application number | Description | Published |
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20090306221 | Use for Cannabinoid - The present invention relates to the use of one or more cannabinoids in the manufacture of medicaments for use in 0 the treatment of diseases and conditions benefiting from inverse agonism of the CB | 12-10-2009 |
Alan Thomas, Newcastle Upon Tyne GB
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20110064655 | BIOMARKERS FOR DEPRESSION - Differential expression of nucleic acids in the brains of subjects suffering from late-onset depression has been demonstrated. The invention provides methods useful in the determination of late-onset depression. Also provided by the present invention is a screening method for the identification of compounds for treatment, prevention or diagnosis of late-onset depression. | 03-17-2011 |
20110064659 | GLUTAMINE BIOMARKERS FOR DEPRESSION - Differential expression of nucleic acids in the brains of subjects suffering from late-onset depression has been demonstrated. The invention provides methods useful in the determination of late-onset depression. Also provided by the present invention is a screening method for the identification of compounds for treatment, prevention or diagnosis of late-onset depression. | 03-17-2011 |
20110091381 | GABA BIOMARKERS FOR DEPRESSION - Differential expression of nucleic acids in the brains of subjects suffering from late-onset depression has been demonstrated. The invention provides methods useful in the determination of late-onset depression. Also provided by the present invention is a screening method for the identification of compounds for treatment, prevention or diagnosis of late-onset depression. | 04-21-2011 |
Alan Thomas, Wiltshire GB
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20100295366 | BRAKE SYSTEM - A brake system for a railway vehicle having wheel slide protection includes a main brake pipe fluidly connected to a distributor, and an auxiliary reservoir fluidly connected to the brake distributor, the distributor being fluidly connected to one or more brake cylinders. A further reservoir is provided, compressed air flow to and from the further reservoir being controllable by a valve, operation of the valve being controlled by a control unit adapted to detect wheel slide. The control unit is adapted to switch air supply between air from the auxiliary reservoir and air from the further reservoir in the event that wheel slide is detected. | 11-25-2010 |
20110049399 | PRESSURE EQUALISATION DEVICE - A pressure equalisation device adapted to be operatively connected to an enclosure, the device including an air passage which, when the device is so connected to the enclosure, provides a fluid communication between the interior of the enclosure and atmosphere, the air passage containing a barrier wall comprising an air permeable membrane forming a micro-particulate filter. | 03-03-2011 |
Alun Thomas, Buckinghamshire GB
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20110231645 | SYSTEM AND METHOD TO VALIDATE AND AUTHENTICATE DIGITAL DATA - A system and method combining registration with a trusted third party, certificate generation, hashing, encryption, customizable file identification fields, and time-stamping technology with recognized “best practice” procedures to achieve the legal admissibility and evidential weight of any form of digital file or collection of digital files. Generally, the originator of the file (the first party) and the originator's employing organization are registered with a Trusted Third Party. The originator reduces the file, by means of a hashing algorithm, to a fixed bit length binary pattern. This provides a unique digital fingerprint of the file. The resultant hash value, the originator's identity details, the employing organization details associated and securely linked to the digital certificate, the title of the file, customizable file identification fields, and other relevant data are forwarded to a Trusted Third Party where the date and time from a known and trusted time source are added. The customizable file identification fields can provide the originator with a mechanism for configuring the seal to incorporate as much additional information as deemed necessary to prove the authenticity of the digital content and/or provide data for the purposes of adding value in functions such as source identification, sorting, analysis, investigation, and compliance. Such information could include, but would not be limited to, location/GPS coordinates, machine id, biometric information, smart-card data, reason for sealing. The original file does not leave the control of the originating party. When combined, the forwarded details and date and time create a Seal Record. The Seal Record is encrypted and hashed. The Seal Record along with all other relevant information are retained on a central secure server. The recipient of the file (the second party) can confirm the file has been received in an unaltered state with integrity retained and it is the authentic version by validating the file. | 09-22-2011 |
Andrew Thomas, Macclesfield GB
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20090131463 | NOVEL COMPOUNDS - The invention provides compounds of formula | 05-21-2009 |
20120095011 | NOVEL COMPOUNDS - The invention provides compounds of formula | 04-19-2012 |
Andrew J. Thomas, Long Wittenham GB
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20100083380 | NETWORK STREAM SCANNING FACILITY - In embodiments of the present invention improved capabilities are described for providing a scanning of data associated with a network computer facility. In the process, a request may be received for network content from a content requesting computing facility. A source lookup associated with the request for network content may be performed, where the source lookup may be from a networked source lookup database. The requested network content may then be retrieved, where the type of the content may be determined as a further aid in scanning the content. A checksum of at least a portion of the retrieved network content may then be calculated, and a checksum lookup associated with the portion of the retrieved network content be performed, where the checksum lookup may be from a networked checksum lookup database. Finally, an action may be taken based on at least one of the source lookup and checksum lookup, where the action is associated with protecting the content requesting computing facility from malware. | 04-01-2010 |
Arwyn Thomas, Brithdir GB
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20110248508 | Electrical machine and permanent-magnet - An electrical machine including a permanent magnet and a coil is provided. The coil is arranged to interact with the permanent magnet via an air gap, which located between the two. Electrical power is generated in the coil when the permanent magnet or the coil is moved in their relative position to each other. The permanent magnet includes a surface, which is aligned to the coil and to the air gap so that that magnetic forces of the permanent magnet interact via the surface and the air gap with the coil by a magnetic flux density distribution. The permanent magnet also includes a base plane and a transition area. A first side of the surface is connected with the adjacent base plane via the transition area. The cross-section of the transition between the surface and the adjacent base plane is determined by a Bezier function. | 10-13-2011 |
20110248594 | Electrical Machine and Permanent-Magnet - An electrical machine including a permanent magnet and a coil is provided. The coil is arranged to interact with the permanent magnet via an air gap, which located between the two. The permanent magnet includes a surface, which is aligned to the coil and to the air gap so that that magnetic forces of the permanent magnet interact via the surface and the air gap with the coil by a magnetic flux density distribution. The surface has a cross-section having a shape that approximates at least partly to a sinusoidal function, causing the magnetic flux distribution in the air gap to be substantially sinusoidal. | 10-13-2011 |
Arwyn Thomas, Sheffield GB
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20090091198 | FLUX-SWITCHING MACHINE - A flux-switching machine stator comprising two or more C-cores, each C-core having two legs and a back portion joining the legs, and a permanent magnet arranged between legs of adjacent C-cores. Each leg has a main portion and a tip portion further from the back portion characterized in that the tip portion of each leg is angled relative to the main portion of the respective leg. | 04-09-2009 |
Arwyn S. Thomas, Llanfyllin GB
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20100072832 | Flux-switching magnetic machine - A flux-switching magnetic machine is provided having a drive element and a driven element. The drive element is configured to generate a composite magnetic field comprising a fixed component and a variable component, the fixed component being generated by spaced fixed field members and the variable component being generated by spaced armature windings. The driven element has a plurality of magnetisable portions configured to be coupled to the composite magnetic field generated by the drive element, such that the driven element moves in response to changes in this field. The number of fixed field members is greater than the number of armature windings. | 03-25-2010 |
Basil John Thomas, Gwent GB
Patent application number | Description | Published |
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20090324346 | Cellular Confinement Systems - A cellular confinement system for soil, sand or other filler material comprises a number of sub-assemblies each made up of a plurality of interconnected open cells of fabric material. The sub-assemblies are stackable one on top of the other to provide a structure having at least one generally vertical side or end wall. The system further comprises sealing means such as one or more skirt portion(s) which are arranged between vertically juxtaposed sub-assemblies in use. The skirt portions substantially prevent or minimise the escape of finer aggregate material from between the stacked sub-assemblies. | 12-31-2009 |
20110033654 | Cellular Structures - A cellular structure includes a plurality of interconnected cells of fabric material. The cells are at least partially filled with a composite fill material that includes a particulate material and a bonding agent. A cellular unit made up of a plurality of the interconnected cells may have an associated load-bearing frame to enable lifting and/or transportation of the structure. The fill material is preferably resilient. | 02-10-2011 |
Bryan Thomas, Bristol GB
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20110180320 | Bracket for attaching an electrical cable to a vehicle - The invention provides a bracket 1 for attaching an electrical cable 6 to a vehicle, the bracket comprising a vehicle attachment portion 11, 31 for attaching the bracket to a vehicle attachment surface of the vehicle, and a cable securing portion 13, 33 for securing the cable to the bracket 1, the cable securing portion 13, 33 comprising a cable abutment portion 4, 8 against the front surface of which the cable 6 can be secured by a cable-tie 7 forming a closed loop around the cable 6 and cable abutment portion 4, 8, and a non-planar rear surface which at least partially defines the path of the closed loop of the cable-tie 7 behind the cable abutment portion 4, 8, the path passing a first region on one side of the non-planar rear surface and a second region on the opposite side of the non-planar rear surface, wherein, in use, the non-planar rear surface directly supports the cable-tie 7 at a third region along the path of the closed loop, the third region being positioned, along the path, between the first and second regions. The invention also provides an aircraft fuel tank comprising a plurality of such brackets 1 and an electrical cable 6, secured to each of the brackets with a cable-tie 7. | 07-28-2011 |
Bryn Thomas, Bristol GB
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20080264245 | Barrier - A passive barrier ( | 10-30-2008 |
Catherine Mary Thomas, Sutton Coldfield GB
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20110257078 | ANTIBACTERIAL COMBINATION THERAPY FOR THE TREATMENT OF GRAM POSITIVE BACTERIAL INFECTIONS - There is described a composition comprising a therapeutically active imidazole, and derivatives thereof, and an agent active on a bacterial cell surface selected from the group consisting of one or more of colistin, nisin, D-cycloserine, fosfomycin, fosfomycin trometamol, fosfomycin disodium and polymixin B, and derivatives thereof. | 10-20-2011 |
Catherine Mary Thomas, Newcastle Upon Tyne GB
Patent application number | Description | Published |
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20100144626 | Treatment of Multi-Drug Resistant Bacterial Infections - There is described an imidazole for the treatment of an infection caused or contributed to by microorganisms resistant to antibiotics. There is also described a method of treating a patient suffering from an infection caused or contributed to by microorganisms resistant to antibiotics, said method comprising the step of administering an effective amount of an imidazole. | 06-10-2010 |
20110020217 | TREATMENT OF MELANOMA - There is described a pharmaceutical composition comprising dexanabinol, or a derivative thereof, in combination with a second therapeutic agent that targets BRAF or MEK, and a pharmaceutically acceptable adjuvant, diluent or carrier. There is also described a method of treating a patient suffering from melanoma and uses related thereto. | 01-27-2011 |
20110033376 | Treatment of Melanoma - There is described dexanabinol, or a derivative thereof, for the treatment of melanoma. There is also described a method of treating a patient suffering from melanoma. | 02-10-2011 |
20110039906 | ANTIBACTERIAL COMBINATION THERAPY - There is described a composition comprising a therapeutically active imidazole, or a derivative thereof, and disulfiram, or a derivative thereof, for treating an infection contributed to or caused by multi-drug resistant bacterial species. | 02-17-2011 |
Christopher John Robert Thomas, Cambridge GB
Patent application number | Description | Published |
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20090249518 | Modification of plant development and morphology - A method of modifying morphology in a plant by introducing into a plant at least one chimaeric gene having a promoter sequence operably associated with a nucleic acid sequence, the promoter sequence being operable to direct expression in specific cells of the plant and the nucleic acid sequence encoding at least one gene product capable of altering the metabolism of or causing death of the specific cells and/or nearby cells. In particular, the promoter sequence is operable to direct expression in lateral bud or lateral shoot and the nucleic acid encoding at least one gene product capable of disrupting the metabolism of or causing the death of the lateral bud or lateral shoot or nearby cells. Preferably the promoter sequence has the sequence shown as SEQ ID No. 1 or SEQ ID No. 7 or SEQ ID No. 4, or a part thereof capable of regulating expression of a gene, or a sequence having at least 60%, preferably at least 75%, homology to SEQ ID No. 1 or SEQ ID No. 7 and being capable of regulating expression of a gene. | 10-01-2009 |
20120011616 | Modification of Plant Development and Morphology - A method of modifying morphology in a plant by introducing into a plant at least one chimaeric gene having a promoter sequence operably associated with a nucleic acid sequence, the promoter sequence being operable to direct expression in specific cells of the plant and the nucleic acid sequence encoding at least one gene product capable of altering the metabolism of or causing death of the specific cells and/or nearby cells. In particular, the promoter sequence is operable to direct expression in lateral bud or lateral shoot and the nucleic acid encoding at least one gene product capable of disrupting the metabolism of or causing the death of the lateral bud or lateral shoot or nearby cells. Preferably the promoter sequence has the sequence shown as SEQ ID No. 1 or SEQ ID No. 7 or SEQ ID No. 4, or a part thereof capable of regulating expression of a gene, or a sequence having at least 60%, preferably at least 75%, homology to SEQ ID No. I or SEQ ID No. 7 and being capable of regulating expression of a gene. | 01-12-2012 |
20140033364 | Modification of Plant Development and Morphology - A method of modifying morphology in a plant by introducing into a plant at least one chimaeric gene having a promoter sequence operably associated with a nucleic acid sequence, the promoter sequence being operable to direct expression in specific cells of the plant and the nucleic acid sequence encoding at least one gene product capable of altering the metabolism of or causing death of the specific cells and/or nearby cells. In particular, the promoter sequence is operable to direct expression in lateral bud or lateral shoot and the nucleic acid encoding at least one gene product capable of disrupting the metabolism of or causing the death of the lateral bud or lateral shoot of nearby cells. Preferably the promoter sequence has the sequence shown as SEQ ID No. 1 or SEQ ID No. 7 or SEQ ID No. 4, or a part thereof capable of regulating expression of a gene, or a sequence having at least 60%, preferably at least 75%, homology to SEQ ID No. 1 or SEQ ID No. 7 or SEQ ID No. 4 and being capable of regulating expression of a gene. | 01-30-2014 |
Christopher Morton Thomas, Birmingham GB
Patent application number | Description | Published |
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20100003738 | PLASMID CURING - The present invention relates to plasmid curing, and particularly to efficient and stress-free methods for displacing resident or endogenous plasmids from a host cell, such as a bacterium. The invention extends to method of displacing a plasmid comprising a post-segregational killing system from a host cell, the method comprising introducing a recombinant nucleic acid molecule into a host cell harbouring a plasmid comprising a post-segregational killing (PSK) system, characterised in that the recombinant nucleic acid molecule is adapted to neutralise the toxic effects of the plasmid's post-segregational killing system, and wherein the nucleic acid molecule is also adapted to outcompete or inhibit replication of the plasmid. The invention further extends to recombinant nucleic acid molecules that can be used in this method, as well as further uses of the methods and nucleic acid molecules of the invention. | 01-07-2010 |
Dafydd Thomas, Holywell GB
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20110295025 | PROCESS FOR THE PREPARATION OF CHOLYL-L-LYSINE - A process for the preparation of cholyl-L-lysine comprising the steps of: —(a) reacting N-ε-CBZ-cholyl-L-lysine with a hydrogen source in the presence of a catalyst in a solvent comprising one or more alkanols; (b) removing the catalyst; (c) optionally diluting the resulting reaction mixture with water and optionally adjusting the pH of the resultant reaction mixture to a pH less than or equal to about 4; (d) removing the bulk of the alkanol whilst ensuring that the alkanol content of the resultant mixture is maintained above about 3% w/w of the remaining mixture; (e) extracting the resultant mixture from step (d) with an organic solvent; (f) adjusting the pH of the aqueous layer to a pH of about 4.5 or greater to precipitate cholyl-L-lysine; (g) isolate the precipitate. | 12-01-2011 |
David Andrew Thomas, Bucks GB
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20120274962 | METHODS AND SYSTEMS TO TROUBLESHOOT MALFUNCTIONS IN MULTIFUNCTION DEVICES USING A WIRELESS HANDHELD DEVICE - The present specification discloses systems and methods for enabling users to troubleshoot multifunction devices using handheld devices, such as mobile phones. In one embodiment, software executing on the handheld device receives data indicative of an error state in a multifunction device, causes the handheld device to obtain and display an image representative of an area of the multifunction device which would need to be serviced to address the error state, determines instructions for addressing the error state, and causes the handheld device to display the instructions in relation to the image representative of an area of the multifunction device. | 11-01-2012 |
David Hywel Thomas, Bromborough GB
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20090130937 | High Temperature Resistant Fibres - Thermal insulation comprises sol-gel formed fibres comprising 10 to 99 mol % of a refractory base composition, and 1 to 90 mol % of a component selected from alkaline earth metal oxides, alkali metal oxides, and mixtures thereof. | 05-21-2009 |
David Stephen Thomas, Cambridgeshire GB
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20120080321 | Display Device - A display device comprises a first insulating substrate ( | 04-05-2012 |
20140004320 | Photopatterning | 01-02-2014 |
Deborah Thomas, West Sussex GB
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20110153476 | SYSTEM AND METHOD FOR DETERMINING TAX LIABILITY IN RESPONSE TO A MOBILITY - A tax event system is configured to evaluate a taxable event that gives rise to tax liability in multiple jurisdictions. The system provides for real time determination of location information (e.g. work location, residence location, assignment location, and the like) for the calculation of tax liability. Such real time analysis allows for transactions to be settled and tax liability to be satisfied in time periods prescribed by various regulating authorities. | 06-23-2011 |
Elfed Thomas, Llandudno GB
Patent application number | Description | Published |
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20100019461 | LAYING NETWORK CABLES IN SEWERS - In the present invention, a cable | 01-28-2010 |
20100084620 | LAYING NETWORK CABLES IN SEWERS - One form of sewer comprises a pipe having a bottom section | 04-08-2010 |
20110309314 | LAYING NETWORK CABLES IN SEWERS - A cable guide includes an upper face and a lower face. The lower face has a generally convex form so as to lie in contact with the flow channel when fitted in the flow channel. The upper face has a generally concave form and is shaped to minimize disturbance of the flow when fitted in the flow channel. A passage is defined between the lower face and the flow channel having an entrance opening at a first end of the cable guide and exit openings on the sides of the cable guide towards a second end. By utilizing a cable guide, disruption to the flow within the channel by the entrance or exit of the cable is minimized. | 12-22-2011 |
20120012386 | LAYING NETWORK CABLES IN WATER SUPPLY PIPES - A network and method of laying network cables in water supply pipes is disclosed. A building is situated near a roadway along which is laid a trunk cable. A water supply pipe branches off the water main to enter the building. A water supply pipe is provided at the time of construction of the building and is an underground pipe. It is conventional to provide a dedicated (and usually underground) conduit for a branch cable, which is expensive and disruptive. In the present invention the branch cable is laid along water supply pipe, enabling the cable to cross between the trunk cable and the building with minimal disturbance of the ground therebetween. This is achieved by introducing cable to pipe by use of a suitable Y-junction at location and removing the cable from the pipe by use of a second such Y-junction at location. | 01-19-2012 |
Gareth David Thomas, Newtown GB
Gareth David Thomas, Hollingworth GB
Patent application number | Description | Published |
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20110123380 | PUMP - A progressive cavity pump is provided, having a stator section and a rotor section axially aligned with and surrounded by the stator section, a drive shaft connection section and a suction chamber, arranged between the stator section and the drive shaft connection section; wherein the suction chamber is configured such that it can be disassembled without moving the stator section or the drive shaft connection section, thereby facilitating the performance of maintenance operations. | 05-26-2011 |
Gareth John Thomas, Bridgend GB
Gareth John Thomas, Sam GB
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20100170118 | EXCAVATOR - An excavator ( | 07-08-2010 |
Gavin Shane Thomas, Cheltenham GB
Patent application number | Description | Published |
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20110302455 | TARGETED BLACK BOX FUZZING OF INPUT DATA - Technologies are described herein for performing targeted, black-box fuzzing of input data for application testing. A dataflow tracing module traces an application while it reads and processes a set of template data to produce operation mapping data that maps data locations in the template data to operations performed by the application in processing the data at the location. The tracing is performed without requiring the application source code, knowledge of the syntactical structure of the input data, or specially instrumented binaries for the application. A fuzzing module is then utilized to target a specific operation or operations in the application by fuzzing data locations within the template data according to the operation mapping data until the desired outcome is achieved. | 12-08-2011 |
Howard Thomas, Aberystwyth GB
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20120061588 | FAECAL MARKERS - Described are methods for analysing an animal carcass, meat obtained therefrom, or product produced by or obtained from an animal for the presence or absence of faecal matter. The methods comprise analysing an animal carcass, meat obtained therefrom, or product produced by or obtained from the animal for the presence or absence of a detectable marker, the presence of the detectable marker being indicative of the presence of faecal matter and the absence of the detectable marker being indicative of the absence of faecal matter, wherein the animal carcass, meat obtained therefrom, or product produced by or obtained from the animal has been obtained from an animal fed a composition comprising a supplement of the detectable marker and/or a precursor thereof. Also described are compositions for feeding to an animal and for use in the methods. | 03-15-2012 |
Howard Thomas, Cambridgeshire GB
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20100055053 | COMBINATIONS FOR ORAL COMPOSITIONS, THEIR PREPARATION AND USE - A composition having a pH in the range of from 3 to 8.5, comprising: (a) in the range of from 0.1% to <10% w/w (based on the total weight of the composition) of a stock solution comprising a mixture of bioflavonoids and fruit acids or salts thereof; (b) sodium hyaluronate; and (c) water; and, optionally, (d) a pharmaceutically acceptable carrier therefor; wherein the sodium hyaluronate has an average molecular weight of between 800,000 and 4,000,000. | 03-04-2010 |
20110294750 | SURFACE STERILISATION BY MISTING WITH A BIOFLAVANOID SOLUTION - There is described a method of sterilizing surfaces using flavonoids, for example mixtures containing inter alia naringin and neohesperidin, by misting. | 12-01-2011 |
Huntly W. Thomas, Hove GB
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20110239630 | CLOSELY COUPLED EXHAUST AFTERTREATMENT SYSTEM FOR AN INTERNAL COMBUSTION ENGINE HAVING TWIN TURBOCHARGERS - A closely-coupled exhaust aftertreatment system for an engine having twin turbochargers includes a first exhaust conduit comprising a first valve operable between first and second positions, the first promoting flow within the first conduit to an oxidation catalyst (OC), the second promoting flow within a second conduit; a third conduit is fluidly coupled to the OC outlet and includes a second valve operable between first and second positions, the first promoting flow within the third exhaust conduit to a particulate filter (PF), the second promoting flow through a fourth conduit to an inlet in the second conduit. A first turbocharger is coupled to the second exhaust conduit downstream of the inlet; an SCR catalyst is downstream of the first turbocharger to receive the flow therefrom and upstream of the PF to provide the flow thereto. A second turbocharger is coupled to the third exhaust conduit downstream of the second valve. | 10-06-2011 |
20110239644 | CLOSELY-COUPLED EXHAUST AFTERTREATMENT DEVICE FOR A TURBOCHARGED INTERNAL COMBUSTION ENGINE - An exhaust aftertreatment system for an internal combustion engine includes an exhaust manifold that is configured for fluid communication with an exhaust port to receive an exhaust gas flow. It also includes a primary turbocharger having a turbine inlet configured for fluid communication with the exhaust manifold to receive the exhaust gas flow and pass it to an outlet. It also includes an exhaust bypass valve that is operable for movement between an open position and a closed position, the exhaust bypass valve having an inlet that is configured for fluid communication with the exhaust manifold in the open position to receive the exhaust gas flow and pass it to an outlet. Still further, it includes an exhaust aftertreatment device configured for thermal communication with the exhaust manifold, the device having an inlet configured for fluid communication with the turbine and bypass outlets to receive the exhaust gas flows therefrom. | 10-06-2011 |
20110239646 | CLOSELY COUPLED EXHAUST AFTERTREATMENT SYSTEM FOR A TURBOCHARGED ENGINE - A closely-coupled exhaust aftertreatment system includes a first exhaust conduit comprising a first valve operable between a first position promoting an exhaust flow within the first exhaust conduit to an inlet of a first oxidation catalyst and a second position promoting the exhaust gas flow within a second exhaust conduit. It also includes a third exhaust conduit fluidly coupled to an outlet of the OC and comprising a second valve operable between a first position promoting an exhaust flow within the third exhaust conduit to an inlet of a particulate filter (PF) and a second position promoting the exhaust gas flow through a fourth exhaust conduit to an inlet in the second exhaust conduit. It further includes a turbocharger fluidly coupled to the second exhaust conduit downstream of the inlet and a selective catalyst reduction (SCR) catalyst that is located downstream of the turbocharger and upstream of the PF. | 10-06-2011 |
James C. Thomas, Newbury GB
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20120290681 | APPLICATION DOWNLOADING - A method, system and computer program product for downloading an application over a network from a remote server to a client device, where the application includes a plurality of modules. A class for each module is created, where the class includes a constructor. A request to use a module of the application is received. Upon receiving the request, a determination is made as to whether the received request is a first request to use the module. If the received request is the first request to use the module, then the requested module is downloaded, the constructor is overwritten with the downloaded module and the constructor within the created class for the requested module is executed. | 11-15-2012 |
James R. Thomas, Cambridge GB
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20080301129 | EXTRACTING AND DISPLAYING COMPACT AND SORTED RESULTS FROM QUERIES OVER UNSTRUCTURED OR SEMI-STRUCTURED TEXT - A system for indexing unstructured or semi-structured data is disclosed. The system may identify regions within the data, such as “Abstract” or “References”. The system may identify linguistic units such as sentences, noun groups, verb groups. The system may also identify concepts such as companies, people, diseases, amounts, and so forth. The query results may be formatted so that similar results from different documents, or from the same document, are clustered together. | 12-04-2008 |
20120089642 | PROVIDING USERS WITH A PREVIEW OF TEXT MINING RESULTS FROM QUERIES OVER UNSTRUCTURED OR SEMI-STRUCTURED TEXT - The system and methods described herein provide results previewing for an interactive text mining system in order to feedback partial query results to users before all results that are responsive to a query have been found. These partial results allow the user to see the progress of their text mining query much sooner. | 04-12-2012 |
20120166426 | EXTRACTING AND DISPLAYING COMPACT AND SORTED RESULTS FROM QUERIES OVER UNSTRUCTURED OR SEMI-STRUCTURED TEXT - A system for indexing unstructured or semi-structured data is disclosed. The system may identify regions within the data, such as “Abstract” or “References”. The system may identify linguistic units such as sentences, noun groups, verb groups. The system may also identify concepts such as companies, people, diseases, amounts, and so forth. The query results may be formatted so that similar results from different documents, or from the same document, are clustered together. | 06-28-2012 |
Jaquin Thomas, Belfast GB
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20090269360 | THERAPY - The invention relates to a method of inhibiting chemotherapy induced upregulation of Cathepsin S on the surface of tumour cells, the method comprising the administration of a Cathepsin S inhibitor to said cells. Also provided is a therapy comprising an anti Cathepsin S antibody, in particular an anti-Cathepsin S antibody which does not inhibit the proteolytic effect of Cathepsin S but nevertheless inhibits angiogenesis and a combination treatment comprising a Cathepsin S inhibitor and a therapeutic agent. | 10-29-2009 |
Jerome Thomas, Tregaron GB
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20080264119 | LOCK | 10-30-2008 |
Jonathan Huw Thomas, Vale Of Glamorgan GB
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20080314389 | Forehead support for a facial mask - A respiratory mask includes a mask frame, a forehead support provided to the mask frame and including a forehead member, and headgear including at least one strap adapted to connect to the forehead member. The forehead member includes one or more holes configured and positioned to allow at least one strap to form a strap loop that loops around at least a portion of the forehead member and arrange one or more layers of the strap loop between the headgear member and the patient's forehead in use. | 12-25-2008 |
Mansel M. Thomas, Suffolk GB
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20110019826 | METHOD OF INSTALLING A WIRELESS NETWORK - A method of method of installing a wireless communications network configures a client device to connect wirelessly to an access point arranged to provide a wireless communications network. The method comprises running an installation program on the client device for configuring the client device to attach to the wireless communications network. The installation program is automatically provided with wireless network configuration information comprising at least a wireless network identifier which identifies traffic using the wireless communications network. The automatic provision of the wireless network configuration information formation comprising said wireless network identifier is implemented by connecting an installation device comprising non-volatile memory which stores said information, and configuring said installation program to utilise the information stored on said installation device. The wireless network configuration information stored on said installation device corresponds to the wireless network configuration of said access point and both the installation device and the access point were configured with the wireless network configuration information prior to said installation device being connected to any client terminal arranged to connect to said access point. | 01-27-2011 |
Marian Thomas, Hertfordshire GB
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20110319371 | PHARMACEUTICAL FORMULATIONS COMPRISING 4-HEXYL)AMINO]-1-HYDROXYETHYL}-2-(HYDROXYMETHYL)PHENOL - Novel pharmaceutical formulations of a beta-2 agonist for inhaled administration via the nose or mouth, and methods of using them are provided. | 12-29-2011 |
Mark A. Thomas, Bedford GB
Patent application number | Description | Published |
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20120047501 | METHODS AND APPARATUS FOR DATA CENTER MANAGEMENT INDEPENDENT OF HYPERVISOR PLATFORM - In some embodiments, an apparatus can include a memory configured to store a first hypervisor message and a second hypervisor message. The apparatus can further include a hypervisor interface module. The hypervisor interface module can retrieve, from the memory, the first hypervisor message and the second hypervisor message. The hypervisor interface module can define a first signal, the first signal being based at least in part on the first hypervisor message and having a first format associated with a first hypervisor platform. The hypervisor interface module can define a second signal, the second signal being based at least in part on the second hypervisor message and having a second format associated with a second hypervisor platform. The hypervisor interface module can send the first signal to a first virtual machine instantiated according to the first hypervisor platform. The hypervisor interface module can send the second signal to a second virtual machine instantiated according to the second hypervisor platform. | 02-23-2012 |
Mark B. Thomas, Southampton GB
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20110197024 | PROVIDING REDUNDANCY IN A VIRTUALIZED STORAGE SYSTEM FOR A COMPUTER SYSTEM - A method for providing redundancy in a virtualized storage system for a computer system is provided. The method includes determining a first set of first logical addresses to provide a virtual storage volume. A redundancy schema is then selected to provide redundancy data for primary data stored in the first set of first logical addresses. A second set of second logical addresses is determined to provide logical storage for the primary data and for the redundancy data. The first set of first logical addresses and the second set of second logical addresses are then mapped and a set of physical storage addresses is selected from a set of physical storage elements. Mapping between the second set of second logical addresses and the set of physical addresses is then performed to provide physical storage for the primary data and the redundancy data stored in the virtual storage volume. | 08-11-2011 |
20130205086 | RAID Array Transformation - Transforming an in-use RAID array from a first array configuration having a first parameter to a second array configuration having a second parameter while preserving the logical data structure. An extent reservation component and data migration component are provided for reading unmigrated data from an area of an array arranged according to the first array configuration and writing the data to an area of the array arranged according to the second array configuration using reserved extents to store first migrated data and using further extents to store second migrated data. A first I/O component for performing I/O according to the first array configuration on unmigrated data prior to its reading by the data migration component is provided along with a second I/O component for performing I/O according to the second array configuration on the first migrated data and the second migrated data after its writing by the data migration component. | 08-08-2013 |
20150019809 | PROVIDING REDUNDANCY IN A VIRTUALIZED STORAGE SYSTEM FOR A COMPUTER SYSTEM - A method for providing redundancy in a virtualized storage system for a computer system is provided. The method includes determining first set of first logical addresses to provide a virtual storage volume, A redundancy schema is then selected to provide redundancy data for primary data stored in the first set of first logical addresses. A second set of second logical addresses is determined to provide logical storage for the primary data and for the redundancy data. The first set of first logical addresses and the second set of second logical addresses are then mapped and a set of physical address es is selected from a set of physical storage elements. Mapping between the second set of second logical addresses and the set of physical addresses is then performed to provide physical storage for the primary data and the redundancy data stored in the virtual storage volume. | 01-15-2015 |
Michael David Ross Thomas, Surrey GB
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20110317895 | Radiotherapy system - A radiotherapy system is disclosed, comprising a support for supporting a patient undergoing radiotherapy treatment, a gantry that is rotatable about an axis, a source of radiation mounted on the gantry and producing a beam of radiation directed towards a target region of the patient, a collimator coupled to said radiation source for collimating said radiation beam, the collimator comprising a plurality of beam-limiting elements, each movable to collectively define a shaped aperture through which the radiation beam passes, a portal imager mounted on the gantry opposite the radiation source for detecting the radiation after it has passed through the patient and generating corresponding images, and associated circuitry for controlling at least the gantry, the source, the collimator, and the portal imager, collating detected data comprising a plurality of images acquired from the imager including images at a plurality of angles of rotation of said gantry and images at a plurality of collimator shapes, and generating a three-dimensional image of the target region based thereon. | 12-29-2011 |
20120281807 | Radiotherapy system - A radiotherapy system comprising a support for a patient undergoing radiotherapy treatment, a gantry rotatable about an axis, a source of radiation mounted on the gantry and producing a beam of radiation directed towards a target region of the patient, a collimator coupled to said radiation source, the collimator comprising a plurality of movable, beam-limiting elements, to collectively define a shaped aperture through which the radiation beam passes, a portal imager mounted on the gantry opposite the radiation source for detecting the radiation after it has passed through the patient and generating corresponding images, and associated circuitry for controlling at least the gantry, the source, the collimator, and the portal imager, collating detected data comprising a plurality of images acquired including images at a plurality of angles of rotation of said gantry and images at a plurality of collimator shapes; generating a three-dimensional image of the target region based thereon. | 11-08-2012 |
Michael P. Thomas, Peacehaven GB
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20110007938 | Thermal and short wavelength infrared identification systems - A method and apparatus for preventing fratricide including an emitter that emits a signaling code at a wavelength, the signaling code representing a coded message; a receiver that captures an image of a field of view including the emitter and generates image information corresponding to the captured image; a translation system that: receives the image information, and decodes the coded message from the image information; and a output device that outputs the decoded message. | 01-13-2011 |
Neil Thomas, Swansea GB
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20110316562 | DISPLACEMENT SENSOR - A linear capacitance displacement transducer ( | 12-29-2011 |
Neil Edwin Thomas, St. Albans GB
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20120313677 | PHASE LOCKED LOOP - A phase locked loop ( | 12-13-2012 |
Neil R. Thomas, Nottingham GB
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20120083599 | Biomolecular Labelling Using Multifunctional Biotin Analogues - Novel biotin analogues, such as 2-Azidobiotin, comprising the ureido ring of natural biotin with the thiophene ring, optionally modified, and a modified sidechain having a functional end group, preferably selected from the group consisting of a carboxylic acid, amine, alcohol, thiol, aldehyde and a halide, and at least one bio-orthogonally reactive chemical group located elsewhere in the sidechain. The analogues are used for labelling target structures and biomolecules, such as peptides and proteins in vitro or in vivo. | 04-05-2012 |
Nicholas Thomas, Radyr Cardiff GB
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20090239292 | MICROFABRICATED APPARATUS FOR CELL BASED ASSAYS - Apparatus and methods are provided for performing cell growth and cell based assays in a liquid medium. The apparatus comprises a base plate supporting a plurality of micro-channel elements, each micro-channel element comprising a cell growth chamber, an inlet channel and an outlet channel, a cover plate positioned over the base plate to define the chambers and connecting channels. Means are incorporated in the cell growth chambers, for cell attachment and cell growth. In particular, the invention provides a rotatable disc microfabricated for performing cell growth and cell based assays. The apparatus and method can be used for the growth of cells and the detection and measurement of variety of biochemical processes and products using non-invasive techniques, that is techniques which do not compromise the integrity or viability of cells. | 09-24-2009 |
20120003682 | MICROFABRICATED APPARATUS FOR CELL BASED ASSAYS - Apparatus and methods are provided for performing cell growth and cell based assays in a liquid medium. The apparatus comprises a base plate supporting a plurality of micro-channel elements, each micro-channel element comprising a cell growth chamber, an inlet channel and an outlet channel, a cover plate positioned over the base plate to define the chambers and connecting channels. Means are incorporated in the cell growth chambers, for cell attachment and cell growth. In particular, the invention provides a rotatable disc microfabricated for performing cell growth and cell based assays. The apparatus and method can be used for the growth of cells and the detection and measurement of variety of biochemical processes and products using non-invasive techniques, that is techniques which do not compromise the integrity or viability of cells. | 01-05-2012 |
Nicholas Thomas, Cardiff GB
Patent application number | Description | Published |
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20100028899 | CELL CYCLE PHASE MARKERS - The present invention relates to polypeptide and nucleic acids constructs which are useful for determining the cell cycle status of a mammalian cell. Host cells transfected with these nucleic acid constructs can be used to determine the effects that test agents have upon the mammalian cell cycle. | 02-04-2010 |
20100233681 | METHOD FOR CELL BASED ASSAYS - Disclosed is a method for cell storage on beads and subsequent utilisation of cryogenically stored cells in cellular assays. | 09-16-2010 |
20100261811 | MICROSCOPY IMAGING PHANTOMS - The invention relates to imaging phantoms for validation, optimisation and calibration of microscopy instrumentation and software used for analysis of microscope images. The materials and methods of the invention find particular use in high content screening and high content analysis. | 10-14-2010 |
20110236921 | CELL SYSTEM - The present invention relates to cellular systems for testing drug candidates and for evaluating the function of mitochondrial proteins. The invention is particularly useful for evaluating drug candidates for cancer and for conducting studies on drug resistance. | 09-29-2011 |
20110267448 | MICROSCOPY - According to one aspect, the present invention relates to an imaging system ( | 11-03-2011 |
20120035859 | METHOD AND APPARATUS FOR MULTI-PARAMETER DATA ANALYSIS - In one aspect, the present invention relates to a method | 02-09-2012 |
20120058467 | APPARATUS AND METHOD FOR DETECTING DNA DAMAGE - The invention relates to an apparatus and an in-situ method for detecting cellular DNA damage. The invention is particularly suited for use in Comet assays and for automation of such assays. The apparatus comprises a multiwell plate, the plate comprising an array of wells held in fixed relationship with each other and each well having an axis, side walls, and a base and wherein the well is provided with electrode pairs disposed therein; and wherein there is provided means for parallel connection of the electrode pairs to an external voltage supply. | 03-08-2012 |
20120258474 | METHODS OF DETECTING DNA DAMAGE - The present invention relates to methods of detecting agents that cause or may potentiate DNA damage, and to assays that may be employed in such methods. In particular, the invention relates to methods of detecting DNA damage in in vitro cultures of human cells. | 10-11-2012 |
20130034272 | SYSTEM AND METHOD FOR DETERMINING MOTION OF A BIOLOGICAL OBJECT - The invention provides a system and method of analysing the motion of a biological object, particularly the motion of cultured organisms or cell cultures. The system and method of the invention may be used to determine the effect of a physical stimulus or a test agent on the motion of cell cultures. The system and method is of particular use in assessing the effect a chemical may have on the contractile motion of cardiomyocyte cell cultures. | 02-07-2013 |
20130177903 | APPARATUS AND METHOD FOR DETECTING DNA DAMAGE - The invention relates to an apparatus and an in-situ method for detecting cellular DNA damage. The invention is particularly suited for use in Comet assays and for automation of such assays. The apparatus comprises a multiwell plate, the plate comprising an array of wells held in fixed relationship with each other and each well having an axis, side walls, and a base and wherein the well is provided with electrode pairs disposed therein; and wherein there is provided means for parallel connection of the electrode pairs to an external voltage supply. | 07-11-2013 |
Nicholas J. Thomas, West Ferry GB
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20110161621 | MICRO-UPDATE ARCHITECTURE FOR ADDRESS TABLES - Methods of maintaining an address table for mapping logical addresses to physical addresses include continuously consolidating main address maps and an update address map, and periodically compacting the update address map. Consolidating includes selecting a main address map, reading valid mapping entries from the main and update address maps, constructing a mapping set including the valid mapping entries, and writing the mapping set to a second main address map. The update address map is compacted if a criterion is met, and includes copying the valid mapping entries to an unwritten block or metablock and assigning the unwritten block or metablock as a new update address map. The length of consolidation may depend on the average length of compacted mapping entries following a compaction operation. Increased performance due to lower maintenance overhead may result by using these methods. | 06-30-2011 |
Nithin Mohan Thomas, Cardiff GB
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20100246816 | DATA ENCRYPTION - A system for encryption, and subsequent decryption, of encoded data allows for transcoding of the encrypted data. The data is encoded in such a way that different packets have different importance levels, so that some or all of the packets at the lower importance levels can be discarded or truncated in order to reduce the data rate. This is achieved by introducing dependencies into the encoding process. The packets at the highest importance level are encoded with reference only to other packets at the highest importance level, while the encoding of packets at lower importance levels also depend on the encoding of the packets at the highest importance level. The encoded data is then encrypted in such a way that the encryption process has dependencies that correspond to the dependencies in the encoding process. Packets at the highest importance level are encrypted with reference to other encrypted packets at the highest importance level, while the encryption of packets at lower importance levels also uses the results of encrypting the packets at the highest importance level. | 09-30-2010 |
Oliver Edward Thomas, Cambridge GB
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20110108712 | PHOTON DETECTOR - A photon detection system comprising an avalanche photodiode and a voltage source for said avalanche photodiode, wherein said avalanche photodiode comprises Silicon or its heterostructures and wherein said voltage source is configured to bias said avalanche photodiode with a voltage component which is static with respect to time and a voltage component which varies with time. | 05-12-2011 |
Owain Rhys Thomas, Vale Of Glamorgan GB
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20100258461 | CASES FOR STORING AN OPTICAL DISC - According to the invention there is provided a case ( | 10-14-2010 |
Pamela Joan Thomas, Hertfordshire GB
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20110014182 | ANTIGEN BINDING PROTEINS - Antigen binding proteins that bind β-amyloid peptide, in particular human β-amyloid peptide; methods of treating diseases or disorders characterised by elevated β-amyloid levels or β-amyloid deposits, particularly Alzheimer's disease and diseases or disorders affecting the eye or optic nerve characterised by elevated β-amyloid levels or β-amyloid deposits, including age related macular degeneration and glaucoma type diseases and β-amyloid dependent cataract formation, with said antigen binding proteins; pharmaceutical compositions comprising said antigen binding proteins; and methods of manufacture. | 01-20-2011 |
Pamela Joan Thomas, Stevenage GB
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20090162358 | ANTIGEN BINDING PROTEINS - Antigen binding proteins that bind β-amyloid peptide, in particular human β-amyloid peptide; methods of treating diseases or disorders characterised by elevated β-amyloid levels or β-amyloid deposits, particularly Alzheimer's disease and diseases or disorders affecting the eye or optic nerve characterised by elevated β-amyloid levels or β-amyloid deposits, including age related macular degeneration and glaucoma type diseases and β-amyloid dependent cataract formation, with said antigen binding proteins; pharmaceutical compositions comprising said antigen binding proteins; and methods of manufacture. | 06-25-2009 |
Paul Thomas, Pimlico GB
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20120058677 | Electrical Plug - This invention relates to an electrical plug ( | 03-08-2012 |
Paul Thomas, County Durham GB
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20080250977 | Oxime free anti-skinning combination - The present invention relates to an antiskinning composition containing an organic oxygen scavenger and at least one drying accelerator. | 10-16-2008 |
Paul Thomas, Leicestershire GB
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20090114145 | DEVICE FOR USE AS A BOOKMARK OR FOR PROMOTIONAL PURPOSES - A bookmark or promotional device comprises a plurality of pockets aligned side-by-side with the opening of the pocket being at the edge of the bookmark. The pockets contain advertising or other promotional material as inserts. The devices are produced in different versions for different audiences and are distributed through a variety of channels generally free of charge to customers. | 05-07-2009 |
20100237601 | DEVICE FOR USE AS A BOOKMARK OR FOR PROMOTIONAL PURPOSES - A device for use for promotional purposes includes first and second cover portions one overlying the other, with generally coextensive side edges in at least a portion thereof. The overlying cover portions define a space therebetween. An arm having a first end and a second end, wherein the first end is rotatably coupled between the first and second cover portions such that the arm can be deployed from a storage position in which the arm is located between the cover portions to an operative position in which the second end is located outside the cover portions. | 09-23-2010 |
Paul Graham Thomas, Bracknell GB
Peter Brian Macfarlane Thomas, Staffordshire GB
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20080200952 | Bone Fixator - Bone fixator for use in the treatment of a fractured bone comprising a support beam having means for attaching each end thereof to the respective ends of a fractured bone, the support beam being configured so as to permit predetermined relative movement between the respective ends of the support beam and thereby transmitting said relative movement to the respective ends of the fractured bone. | 08-21-2008 |
20080300606 | Wire Retainer for Surgical Device - A wire retainer ( | 12-04-2008 |
Peter Robert Thomas, Cotesbach GB
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20080231603 | Touch Screens - A touch screen control system comprising a touch screen ( | 09-25-2008 |
20110141041 | TOUCH SCREENS - A touch screen control system comprising a touch screen having first and second conductive layers arranged to be brought together by touching of the screen. A detection system is arranged to detect a contact position at which the screen is touched by monitoring electrical signals from at least one of the layers. The system further comprises an antenna, and the detection system includes a proximity sensing signal generator arranged to generate a proximity sensing signal to be transmitted between the antenna and the first layer via a user of the system. The detection system is further arranged to receive the transmitted proximity sensing signal and determine therefrom the distance between a part of the user and the touch screen. | 06-16-2011 |
Peter Stanley Thomas, Saffron Walden GB
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20090137549 | Novel compounds useful for the treatment of degenerative & inflamatory diseases - The present invention relates to compounds that are inhibitors of PDE1A, a phosphodiesterase that is involved in the modulation of the degradation of cartilage, joint degeneration and diseases involving such degradation and/or inflammation. | 05-28-2009 |
Rhian Sara Thomas, Cradiff GB
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20100239591 | MONOCLONAL ANTIBODY FOR APP - The invention relates to a novel peptide, polypeptide or monoclonal antibody for use in the treatment of conditions characterised by elevated levels of β-amyloid (Aβ 39-43 amino acid peptide) in a subject, especially Alzheimer's Disease. The invention particularly relates to an amyloid precursor protein (APP)-binding polypeptide which, when administered outside an APP-expressing cell, reduces the release of Aβ 39-43 by the cell. | 09-23-2010 |
Robert Victor Thomas, Wimborne GB
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20100328037 | RFID MONITORING SYSTEM - A radio frequency identification (RFID) monitoring system ( | 12-30-2010 |
Roger Thomas, Cleveland GB
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20090049972 | Footplate - A footplate for a power tool for guiding the tool along a guide, the footplate having on its lower surface at least one dual-restriction , wherein the first part of the dual-restriction is for engaging a rail extending in a longitudinal direction of a first guide on the upper surface of said first guide and the second part of the dual-restriction is for engaging a rail extending in a longitudinal direction of a second different guide on the upper surface of said second guide, where the first and second parts of the or each dual-restriction each has a fixed side wall, and where the first and second parts of the or each dual-restriction have an adjustable side wall arranged opposite to a respective fixed side wall. | 02-26-2009 |
20090133559 | Power tool - A power tool comprising a housing displaceably mounted to a foot plate, a blade, a motor, an electric switch and an interlock for controlling movement of the housing with respect to the foot plate. The interlock has a control button mounted to one of the housing or foot plate which cooperates with a channel fixed in relation to the other of the housing or foot plate. The control button can select between a plunge cut mode wherein the blade can protrude below the foot plate, or a blade change mode wherein the blade is prepared for a blade change operation. The channel comprises a major leg in communication with a minor leg. Cooperation between the control button and the major leg selects the plunge cut mode. Cooperation between the control button and the minor leg selects the blade change mode. The interlock may also comprise a housing lock and a spindle lock. | 05-28-2009 |
Roger Thomas, Sedgefield GB
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20090049970 | Anti-Kickback Device - The present invention provides an anti-kickback for arresting movement of a rail accommodated within an elongate channel. The anti-kickback device includes a slide member arranged to slide along a slide surface between an extended position and a retracted position. The device further includes a resilient member, housed in a sleeve, which biases the slide member along the slide surface. The slide member, when in the extended position, is designed to urge the rail into abutment with a wall of the channel to arrest movement of the rail accommodated within the channel. | 02-26-2009 |
Roger Thomas, Swansea GB
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20120107132 | TITANIUM ALLOY WITH IMPROVED PROPERTIES - A titanium alloy having high strength, fine grain size, and low cost and a method of manufacturing the same is disclosed. In particular, the inventive alloy offers a strength increase of about 100 MPa over Ti 6-4, with a comparable density and near equivalent ductility. The inventive alloy is particularly useful for a multitude of applications including components of aircraft engines. The Ti alloy comprises, in weight percent, about 6.0 to about 6.7% aluminum, about 1.4 to about 2.0% vanadium, about 1.4 to about 2.0% molybdenum, about 0.20 to about 0.42% silicon, about 0.17 to about 0.23% oxygen, maximum about 0.24% iron, maximum about 0.08% carbon and balance titanium with incidental impurities. | 05-03-2012 |
Rolf L. Thomas, West Sussex GB
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20090048592 | Electrosurgical instrument - An electrosurgical instrument for the treatment of tissue in the presence of an electrically-conductive fluid medium comprises an instrument shaft ( | 02-19-2009 |
Roy Thomas, Bolton GB
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20100175439 | LOCKING APPARATUS - A locking apparatus having a body, at least one arm and a tapered member; wherein relative movement between the arm and the tapered member extends the arm from the body. In use, the arm is arranged to press against a wall of a channel to hold the locking apparatus in place and prevent the opening of a roller shutter. | 07-15-2010 |
Russel J. Thomas, Boars Hill Oxford GB
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20100029719 | ARYLSULFONAMIDE DERIVATIVES AS C-JUN-N-TERMINAL KINASES (JNK'S) INHIBITORS - The present invention relates to sulfonamide derivatives of formula I notably for use as pharmaceutically active compounds, as well as to pharmaceutical formulations containing such sulfonamide derivatives. Said sulfonamide derivatives are useful in the treatment of neuronal disorders, autoimmune diseases, cancer and cardiovascular diseases. Furthermore, said sulfonamide derivatives are efficient modulators of the JNK pathway, they are in particular efficient and selective inhibitors of JNK2 and -3. The present invention is furthermore related to novel sulfonamide derivatives as well as to methods of their preparation. | 02-04-2010 |
Russell M.i. Thomas, Treorchy GB
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20120329081 | SAMPLING DEVICES AND METHODS OF USE - Sample-collecting devices, articles and methods of use are disclosed. Premoistened sample-collecting devices comprise 1,2-propanediol as a humectant, which promotes the retention of a liquid solution on the sample-collecting device during storage. 1,2-propanediol as humectant can be compatible with proteins and other reagents used to detect an analyte. | 12-27-2012 |
Sean Julian Thomas, Merseyside GB
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20090275825 | TUBE FOR DELIVERING A FLUID TO A PREDETERMINED LOCATION - A tube for delivering fluid to a remote location not normally in view or not practicably able to be viewed by an operator placing such tubes. The tube comprising a lumen connecting a fluid input aperture, disposed at a proximal end of the tube, and a fluid output aperture, to deliver fluid therebetween. The tube further comprises positioning means having an optical waveguide and sensor means. The optical waveguide extends from the proximal end of the tube to the sensor means. The optical waveguide guides an input optical signal to the sensor means. Positioning of the sensor means in a desired location within a system varies the properties of the input optical signal to provide a predetermined output optical signal, which is guided to the proximal end of the tube to indicate to a user, placement of the predetermined portion of the tube at the desired position within the system. | 11-05-2009 |
Simon Thomas, East Sussex GB
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20100306002 | METHOD AND SYSTEM FOR CALCULATING AN ENVIRONMENTAL SCORE FOR A BUSINESS UNIT - A computer system is provided for calculating an environmental impact for a separately accountable business unit. The system accesses accounts data indicative of internal costs for the separately accountable business unit and supplier costs comprising costs paid to suppliers for goods or services used in the economic activities of the separately accountable business unit. The internal costs and supplier costs of the accounts data are processed to determine the environmental impact for the separately accountable business unit, wherein the environmental impact comprises the impact on the environment as a consequence of the economic activities of the separately accountable business unit. | 12-02-2010 |
Stephen Gregory Thomas, Harpenden GB
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20100031390 | Gibberellin 2-Oxidase - A nucleic acid sequence is provided which encodes a gibberellin 2-oxidase gene which catalyses the 2β-oxidation of a gibberellin molecule to introduce a hydroxyl group at C-2 and further catalyses the oxidation of the hydroxyl group introduced at C-2 to yield the ketone derivative. Such sequences can find application in the preparation of transgenic plants with altered levels of gibberellin 2-oxidase. | 02-04-2010 |
Stephen Paul Thomas, High Wycombe GB
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20120278581 | METHOD AND SYSTEM FOR DYNAMIC MEMORY MANAGEMENT - A computer system which includes a plurality of threads and a garbage collector that traces memory objects and identifies memory objects according to a three-color abstraction. The computer system also includes two methods of deleting compiled code in a self-modifying multi-threaded computer system. The computer system also utilizes a method of handling links between fragments of code in a self-modifying multi-threaded computer system. The computer system also handles patches between two pieces of code. | 11-01-2012 |
Steven Thomas, Cheshire GB
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20110005042 | ZIP FASTENER - A zip fastener including fabric tapes having coupling elements thereon is provided. A coating layer of thermoplastic material is provided on at least one first surface of the fastener tapes. The coating layer extends continuously along the first surface, extends over an edge of the fastener tapes and extends along at least one second surface of the fastener tapes. | 01-13-2011 |
20120023713 | Waterproof Slide Fastener and Method of Applying Fluid Tight Coating to Tape - A waterproof slide fastener is provided. A pair of tapes has coupling elements attached thereto. A coating of polymeric material is provided on at least one surface of the tape and extends continuously therealong. The coating includes in cross-section a fin with a bulbous region. The coating is not extendable beyond the coupling elements when the slide fastener is in an open arrangement. | 02-02-2012 |
20140359979 | Method of Manufacturing Portion of Slide Fastener - A method of manufacturing a portion of a slide fastener. The method comprises providing a first tape having a first edge; providing the first tape with a row of coupling elements along the first edge of the first tape, the coupling elements being configured to interdigitate with a further row of coupling elements. The method further comprises attaching a first layer of a fluid resistant material to the first tape, attaching an extending layer of a fluid resistant material to the first layer, the extending layer forming an extension member comprising a first overhang portion which extends beyond a second edge of the first tape opposite the first edge of the first tape. The first layer of fluid resistant material is attached to the first tape and the extending layer is attached to the first layer such that there is no fluid path through the first layer and/or extending layer to the first tape. | 12-11-2014 |
Trevor Thomas, Cambridge GB
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20090086934 | Device for Modifying and Improving the Behaviour of Speech Recognition Systems - A speech recognition system comprises a controller application, a speech recogniser, and a modification apparatus disposed between them. The controller application has an output arranged to produce a speech signal, an input arranged to receive a recognised speech result signal and a control command output arranged to produce a command signal. The speech recogniser has a pattern matcher, a speech input arranged to receive the speech signal from the controller application, an output arranged to produce the recognised speech recognised signal and a control command input arranged to receive the command signal. The modification apparatus is disposed between the output of the controller application and the input of the speech recogniser; between the output of the speech recogniser and the input of the controller application; and between the control command output of the controller application and the control command input of the speech recogniser. The modification apparatus is arranged to modify at least one of the signals between the controller application and the speech recogniser. In this way speech recognition accuracy can be significantly improved. | 04-02-2009 |
Wayne Morris Thomas, Suffolk GB
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20100279146 | REFRACTORY METAL TOOL FOR FRICTION STIR WELDING COMPRISING A SHOULDER MADE OF TUNGSTEN, MOLYBDENUM, TANTALUM, NIOBIUM OR HAFNIUM ALLOY AND A COATED OR TREATED SURFACE - A tool for friction stir welding or forming is provided. The tool comprises a shoulder portion ( | 11-04-2010 |