Mihov
George Mihov, Maastricht NL
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20120177703 | SOLID LINEAR OLIGO-OR POLY-E-CAPROLACTONE - The present invention relates to linear oligo- or poly-ε-caprolactones di-blockcopolymers, in solid form at room temperature, comprising monoalkyl oligoethyleneglycol residues. The present invention further relates to a drug delivery formulation comprising above materials and a process for the preparation of the drug delivery formulation. The oligoethyleneglycol residues are preferably selected from the group consisting of methyl diethylene glycol, methyl triethyleneglycol or methyl tetraethylene glycol. The oligo- or poly-ε-caprolactone derivatives are prepared via the reaction of mono-hydroxy-oligoethyleneglycol with ε-caprolactone, whereby the mono-hydroxy-oligoethyleneglycol acts as an initiator. | 07-12-2012 |
George Mihov, Ex Maastricht NL
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20120282299 | COATINGS COMPRISING BIS-(ALPHA-AMINO-DIOL-DIESTER) CONTAINING POLYESTERAMIDE - The present invention relates to a coating comprising at least one biodegradable polymer, wherein the polymer comprises at least one or a blend of a poly (ester amide) (PEA) having a chemical formula described by structural formula (II), wherein; R | 11-08-2012 |
George Mihov, Echt NL
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20140105957 | BIS-(ALPHA-AMINO-DIOL-DIESTER) CONTAINING POLYESTERAMIDE FOR OPHTAMOLOGY - The present invention relates to an ocular polymer delivery composition comprising at least one ophthalmologic agent dispersed in at least one biodegradable polymer, wherein the polymer comprises at least one of a poly (ester amide) (PEA) having a chemical formula described by structural formula (I). | 04-17-2014 |
20140120170 | PARTICLES COMPRISING POLYESTERAMIDE COPOLYMERS FOR DRUG DELIVERY - The present invention relates to micro- or nanoparticles comprising a polyesteramide (PEA) having a chemical formula described by structural formula (IV), Formula (IV) wherein —m+p varies from 0.9-0.1 and q varies from 0.1 to 0.9 —m+p+q=1 whereby m or p could be 0-n is about 5 to about 300; (pref 50-200) —R | 05-01-2014 |
20140179802 | FIBER COMPRISING A BIODEGRADABLE POLYMER - The present invention relates to a fiber comprising a biodegradable polymer which undergoes dimensional change upon injection in the human or animal body wherein the dimensional change is a reduction of the surface area to volume ratio of a factor 2 to 10. The fiber is sized for injection via a pharmaceutical syringe needle having a bore of at least 25 Gauge. The biodegradable polymer is an amorphous biodegradable polymer selected from the group of poly-hexamethylene carbonates or polyesteramides. The amorphous biodegradable polymer is a preferably a polyesteramide comprising alpha-amino acids, diols and dicarboxylic acids as building blocks. The invention further relates to the use of the fiber for the manufacturing of a medicament for the treatment of ophthalmic diseases. The invention also relates to a process for the manufacturing of the fiber comprising the following process steps; a. extruding a biodegradable polymer into a fiber fitting in a needle of at least 25 Gauge b. which while under tension is cooled below its glass transition temperature such that the resultant fiber is amorphous. | 06-26-2014 |
20140220099 | BIODEGRADABLE POLYESTERAMIDE COPOLYMERS FOR DRUG DELIVERY - The present invention relates to a poly (ester amide) (PEA) having a chemical formula described by structural formula (IV), wherein m+p varies from 0.9-0.1 and q varies from 0.1 to 0.9 m+p+q=1 whereby m or p could be 0 n is about 5 to about 300; (pref. 50-200) R | 08-07-2014 |
Slavi Mihov, Sofia BG
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20090316929 | SOUND CAPTURE SYSTEM FOR DEVICES WITH TWO MICROPHONES - The perceptual sound quality of desired audio signals (e.g., human voice) captured by an electronic device (e.g., cell phone) are improved by reducing ambient noise according to an algorithm that acts upon audio signals captured from a front and rear direction. More particularly, audio signals captured by two directional microphones pointing in opposite directions (e.g., a front microphone which receives audio signals from a forward direction and a rear microphone which receives audio signals from a rear direction) are classified and subsequently enhanced (e.g., unwanted signals are suppressed) according to a probability of their source (e.g., front, rear, or noise) thereby providing an improved perceptual sound recording than each microphone individually. The resultant signals provide decreased noise since the contribution of the front and rear microphones are taken into consideration and the signal from the more relevant (e.g., in the direction from which sound is coming) microphone is utilized. | 12-24-2009 |
Valentin Stoyanov Mihov, Sofia BG
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20130305149 | DOCUMENT READER AND SYSTEM FOR EXTRACTION OF STRUCTURAL AND SEMANTIC INFORMATION FROM DOCUMENTS - Embodiments of the invention disclose a method and a system for processing and reading/viewing and otherwise consuming electronic documents. Said processing may include the extraction of structural and semantic Information from documents; and displaying the documents to a viewed in an interactive manner | 11-14-2013 |