Kellam
Barrie Kellam, Funtham GB
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20130261178 | PHENOXYPROPANOL DERIVATIVES AND THEIR USE IN TREATING CARDIAC AND CARDIOVASCULAR DISEASES - A compound of formula I-0, and its pharmaceutically acceptable salt or salts and physiologically hydrolysable derivatives in free form or salt form: | 10-03-2013 |
Barrie Kellam, Nottingham GB
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20090093001 | HIGH CONTENT SCREENING - A high content screening (HCS) assay for rapidly screening one or more compounds to determine functional response or pharmacological properties thereof, comprising: i) priming a cell or cell material with a sensor for a biological response; ii) contacting the compound(s) to be tested with the primed cell or cell material or contacting a cell or cell material which has been contacted with the compound(s) with the primed cell or cell material; iii) simultaneously or subsequently contacting with a fluorescent agonist or a fluorescent neutral antagonist wherein the binding of the fluorescent agonist or antagonist and its associated biological response are detected or monitored in the same cell and are distinct allowing separate readout. | 04-09-2009 |
20110300116 | Method for Generating a Recombinant Clonal Cell Line and Novel Reagents for Use in the Method - A method for generating a recombinant clonal cell line expressing a target cell surface receptor at a specific level of expression from a cell population comprising cells transfected with a plasmid encoding the cDNA sequence of the target receptor and expressing the target cell surface receptor, the method comprising (c) incubating the cell population with a receptor specific fluorescent ligand (d) selecting single cells from step (c) expressing the target cell surface receptor by monitoring the specific binding of the fluorescent ligand using flow cytometry; and novel fluorescent ligands. | 12-08-2011 |
20140094493 | Novel Ether Linked Compounds and Improved Treatments for Cardiac and Cardiovascular Disease - A compound of Formula (I), and its pharmaceutically acceptable salt or salts and physiologically hydrolysable derivatives in free form or salt form: | 04-03-2014 |
20150051270 | Novel Cyclic Phenoxy Compounds and Improved Treatments for Cardiac and Cardiovascular Disease - A compound of formula I, and its pharmaceutically acceptable salt or salts and physiologically hydrolysable derivatives in free form or salt form: | 02-19-2015 |
Benjamin Kellam, Dunedin, FL US
Patent application number | Description | Published |
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20090312694 | DISTRIBUTED PROCESSING SYSTEM AND METHOD FOR DIALYSIS MACHINES - A dialysis machine includes a control unit having a user interface; a heater(s) located separate from the control unit; a supervisory processor located with the control unit; a delegate control processor located with the heater(s), the delegate control processor in communication with the supervisory processor and configured to receive load cell, heater(s) plate and supply bag temperature sensor inputs; and a sub-delegate heater(s) processor in communication with the control processor and configured to control power to the heater(s). The machine can also include primary and secondary monitoring processors that perform a safety check to the control processing and monitor the load cell. | 12-17-2009 |
20100010425 | PERITONEAL EQUILIBRATION TEST AND DIALYSIS SYSTEM USING SAME - An ultrafiltration (“UF”) evaluation method includes: (i) determining an amount of UF removed from a patient over a first dwell time; (ii) determine an amount of UF removed from the patient over a second, different dwell time; (iii) determining an amount of UF removed from the patient over a third, different dwell time; and (iv) fitting a curve to the UF removal amounts for the first, second and third dwell time. A peritoneal dialysis therapy generation method using the curve determined according to the “UF” evaluation method to generate at least one peritoneal dialysis therapy regimen. | 01-14-2010 |
Benjamin Kellam, Clearwater, FL US
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20110106003 | DIALYSIS SYSTEM AND METHOD FOR CASSETTE-BASED PUMPING AND VALVING - A peritoneal dialysis system includes a disposable cassette including a flexible sheet; a hardware unit including (i) at least one pump actuator and piston head moved by the pump actuator, (ii) at least one valve actuator, (iii) at least one sensor, and (iv) a disposable cassette interface for interfacing with the disposable cassette, the disposable cassette interface including: (a) at least one pump aperture, the at least one piston head moveable out of and retractable into the at least one pump aperture to move a corresponding pumping portion of the flexible sheet of the disposable cassette, the piston head moving within a vacuum chamber, the vacuum chamber enabling a vacuum to be pulled around the piston head to the flexible sheet of the disposable cassette; (b) at least one valve aperture, at least a portion of the at least one valve actuator located in the valve aperture to move a valve portion of the flexible sheet of the disposable cassette; and (c) at least one sensor aperture, the at least one sensor located in the at least one sensor aperture, the at least one sensor operable with a sensor portion of the flexible sheet of the disposable cassette. | 05-05-2011 |
David M. Kellam, Stratford CA
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20100014792 | AUTOMOTIVE STRUT RING BEARING ASSEMBLY WITH SPRING SEAT AND INTEGRAL DAMPENING MEMBER - A ring bearing assembly for an automotive suspension strut assembly. The ring bearing assembly includes an annular bearing having a lower housing member that functions as an integral spring seat for the suspension's coil spring. An isolator is molded to the spring seat as an integral component with a groove or other mechanical retention feature being used to help maintain the isolator in place and prevent it from working itself out of position over time during vehicle use. | 01-21-2010 |
20100040317 | SLIDING STRUT BEARING - The sliding strut bearing has two rigid body positioned in a plastic housing and a synthetic resin sliding bearing positioned between the two rigid bodies. The rigid bodies are metal and provide structural rigidity allowing a spring seat to be incorporated into the plastic housing and an overall reduction in the height of the bearing. | 02-18-2010 |
Doug Kellam, Oak Brook, IL US
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20160023918 | SYSTEMS AND METHODS OF ELIMINATING FILTER AIR LOCKS - Systems and methods of eliminate filter air locks by maintaining a constant water table at the water head layer of the filter. The constant water table eliminates air locks in the filter as the filter drains. Water flows from the water head layer through a filtration medium in a filter cartridge, and the filtered water is output from a water outlet at the top of the cartridge. For a water table retention filter, where the water (or other liquid) being filtered, is re-directed to the top of the filter to the water head layer to avoid drawing air into the filter. Unfiltered water drains down the center of the filter to the water head layer and then flows up through the filter and is directed out near or at the top of the filter. | 01-28-2016 |
Gary Kellam, Albuquerque, NM US
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20100226106 | Circuit Board Retainer - An assembly for retaining a board such as a printed circuit board in the groove of a plate such as a cold plate. The retaining assembly includes an elongate open bracket or sleeve defining an interior channel which houses an elongate rod and an elongate cradle for the rod. In one embodiment, the cradle is defined by a separate beam which is seated in the channel and the open bracket is a generally U-shaped unitary strip of material which includes a flexible wall which is deflected outwardly in response to rotation of the rod into engagement with an interior wall of the cold plate for locking the board in the groove of the cold plate. The open bracket also includes a securement wall opposite the flexible wall which, in one embodiment, is secured to the cold plate. | 09-09-2010 |
Jeffrey J. Kellam, Austin, TX US
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20110286386 | Reliable Transfer of Time Stamped Multichannel Data Over A Lossy Mesh Network - System and method for transmitting data over a wireless medium. A wireless sensor node receives data from at least one sensor, where the data include a plurality of data sets. For each data set: the wireless sensor node compares the size of the data set with a specified packet size, and if the size of the data set exceeds the specified packet size, transmits a plurality of packets containing respective portions of the data set to a gateway device over a wireless medium. If the size of the data set does not exceed the specified packet size, then a packet containing the data set is transmitted to the gateway device over the wireless medium. | 11-24-2011 |
20150301085 | Automatically Capturing Data Sets of Interest from a Data Acquisition Data Stream - Capturing datasets of interest from a data acquisition data stream. An acquired dataset may be received from a measurement device. The acquired dataset may include measurement data from measurements of one or more physical phenomena acquired by the measurement device, and may be a current dataset in a sequence of datasets acquired by the measurement device. The acquired dataset is buffered, resulting in a buffered dataset. One or more thresholds specifying datasets of interest may be automatically determined based on the buffered dataset or one or more previously acquired datasets. The buffered dataset may be automatically analyzed with respect to the one or more thresholds, and a determination may be made as to whether the buffered dataset is a dataset of interest based on said automatically analyzing. In response to determining that the buffered dataset is a dataset of interest, the buffered dataset may be stored in a storage medium. | 10-22-2015 |
John A. Kellam, Basking Ridge, NJ US
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20140171223 | Golf tee with spark induction coating and method for improving golf performance - A golf tee having a contact alert coating provides a novel training aid that is economical, compact, and encourages proper golfing form. The golf tee has a golf tee body with a top plate, top wall and side walls. The top plate is fixedly attached to a shaft which terminates into a point that is inserted into a ground surface when a ball is placed on the top plate. A contact alert coating is coated on at least an upper portion of the golf tee body. The contact alert coating is composed of a material that will generate an alert when a golf club head strikes the ball and strikes the contact alert coating of the golf tee at the coating/golf tee interface. Preferably, the material is a spark inducing composition and/or a sound generating composition. | 06-19-2014 |
20140236793 | Business And Professional Network System And Method For Identifying Prospective Clients That Are Unlikely To Pay For Professional Services - A business network system identifies prospective clients having delinquent accounts open with subscribers, including businesses or professionals, of the network system. The business network system associated with software provides entry of subscriber information within a subscriber database storing subscriber registration and client information and networking subscriber information. A client database is promulgated through the client information from the subscriber. The client database stores payment history information associated with at least one subscriber of the database. The payment history includes entry of any outstanding account balances owed by the client to any of the subscribers. Advantageously, the client database lists non-paying clients so that the subscribers can elect to avoid taking on the client as a perspective client and refuse to perform services for the client. | 08-21-2014 |
Mark Kellam, Siler City, NC US
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20130062587 | Resistive Switching Devices Having Alloyed Electrodes And Methods of Formation Thereof - In accordance with an embodiment of the present invention, a resistive switching device comprises a bottom electrode, a switching layer disposed over the bottom electrode, and a top electrode disposed over the switching layer. The top electrode comprises an alloy of a memory metal and an alloying element. The top electrode provides a source of the memory metal. The memory metal is configured to change a state of the switching layer. | 03-14-2013 |
Mark D. Kellam, Pittsboro, NC US
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20100025811 | INTEGRATED CIRCUIT WITH BUILT-IN HEATING CIRCUITRY TO REVERSE OPERATIONAL DEGENERATION - An integrated circuit device ( | 02-04-2010 |
20120286330 | PLANAR MOSFET WITH TEXTURED CHANNEL AND GATE - A semiconductor device is disclosed that includes a semiconductor substrate having a channel region and respective source and drain regions formed on opposite sides of the channel region. The channel region includes at least one pore. A gate is formed on the semiconductor substrate between the source and drain regions and includes at least one pin received by respective ones of the at least one pore. A dielectric layer is disposed between the gate and the semiconductor substrate. | 11-15-2012 |
Mark D. Kellam, Siler City, NC US
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20110286280 | Pulse Control For NonVolatile Memory - This disclosure provides a nonvolatile memory device that uses pulsed control and rest periods to mitigate the formation of defect precursors. A first embodiment uses pulsed bitline control, where the coupling between a memory cell channel and a reference voltage (selected in response to the bitline) is pulsed when it is desired to change state in the associated memory cell. Each pulse may be chosen to be less than about (20) nanoseconds, while a “rest period” between pulses typically is chosen to be on the order of about a hundred nanoseconds or greater (e.g., one microsecond). Because bitline control is used, very short rise times can be enabled, enabling generation of pulse durations of (50) nanoseconds or less. In other embodiments, these methods may also be more generally applied to other conductors (e.g., wordline or substrate well, for program or erase operations); if desired, segmented wordlines or bitlines may also be used, to minimize RC loading and enable sufficiently short rise times to make pulses robust. | 11-24-2011 |
20120211722 | THREE-DIMENSIONAL MEMORY ARRAY STACKING STRUCTURE - A memory device includes a planar substrate, a plurality of horizontal conductive planes above the planar substrate, and a plurality of horizontal insulating layers interleaved with the plurality of horizontal conductive planes. An array of vertical conductive columns, perpendicular to the pluralities of conductive planes and insulating layers, passes through apertures in the pluralities of conductive planes and insulating layers. The memory device includes a plurality of programmable memory elements, each of which couples one of the horizontal conductive planes to a respective vertical conductive column. | 08-23-2012 |
20130148437 | THERMAL ANNEAL USING WORD-LINE HEATING ELEMENT - In response to detecting an event during operation of an integrated-circuit memory device containing charge-storing memory cells, an electric current is enabled to flow through a word line coupled to the charge-storing memory cells for a brief interval to heat the charge-storing memory cells to an annealing temperature range. | 06-13-2013 |
20130242640 | Methods and Systems for Resistive Change Memory Cell Restoration - A resistive change memory device includes a first conductive line, a second conductive line, and a resistive change memory cell that includes a resistive memory element coupled between the first conductive line and the second conductive line. The resistive change memory device also includes control circuitry to apply, via the first conductive line and the second conductive line, a first biasing condition to the resistive change memory cell for a reset operation and a second biasing condition to the resistive change memory cell for a restore operation. The restore operation is performed to counteract a decrease in resistance of the resistive memory element for a reset state of the resistive change memory cell. At least one of a voltage, current, and duration of the second biasing condition is greater than a corresponding voltage, current, or duration of the first biasing condition. | 09-19-2013 |
20130250657 | System and Method for Writing Data to an RRAM Cell - A resistive RAM device includes a bit line, a word line, an RRAM cell coupled to the word line and to the bit line, a write driver and a disable circuit. The write driver is coupled to the bit line. The disable circuit stops a write operation performed by the write driver on a respective RRAM cell when a predefined condition on the bit line is achieved. The predefined condition depends on a mode of operation of the RRAM cell. | 09-26-2013 |
20140112058 | RESISTANCE MEMORY CELL - A resistance memory includes a resistance memory cell having a resistance memory element and a two-terminal access device in series. The two-terminal access device affects the current-voltage characteristic of the resistance memory cell. The resistance memory additionally includes a circuit to apply across the resistance memory cell a set pulse having a set polarity to set the resistance memory cell to a low-resistance state that is retained after application of the set pulse, a reset pulse having a reset polarity, opposite to the set polarity, to reset the resistance memory cell to a high-resistance state that is retained after application of the reset pulse, and a read pulse of the reset polarity and smaller in magnitude than the reset pulse to determine the resistance state of the resistance memory cell without changing the resistance state of the resistance memory cell. | 04-24-2014 |
20140247656 | Pulse Control For NonVolatile Memory - A nonvolatile memory device that uses pulsed control and rest periods to mitigate the formation of defect precursors. A first embodiment uses pulsed bitline control, where the coupling between a memory cell channel and a reference voltage is pulsed when it is desired to change state in the associated memory cell. Each pulse may be chosen to be less than about 20 nanoseconds, while a “rest period” between pulses can be on the order of about a hundred nanoseconds or greater. Because bitline control is used, very short rise times can be enabled, enabling generation of pulse durations of 50 nanoseconds or less. In other embodiments, these methods may also be more generally applied to other conductors (e.g., wordline or substrate well, for program or erase operations); segmented wordlines or bitlines may also be used, to minimize RC loading and enable sufficiently short rise times to make pulses robust. | 09-04-2014 |
20140254286 | THERMAL ANNEAL USING WORD-LINE HEATING ELEMENT - In response to detecting an event during operation of an integrated-circuit memory device containing charge-storing memory cells, an electric current is enabled to flow through a word line coupled to the charge-storing memory cells for a brief interval to heat the charge-storing memory cells to an annealing temperature range. | 09-11-2014 |
Mark D. Kellam, Siler, NC US
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20100207189 | NON-VOLATILE MEMORY DEVICE WITH REDUCED WRITE-ERASE CYCLE TIME - A transistor includes a substrate having a surface, where a first region and a second region of the substrate are doped with a first type of dopant, and where a third region of the substrate between the first region and the second region is doped with a second type of dopant. An insulator layer is deposited above a portion of the surface, which includes the third region, and a gate layer is deposited above the insulator layer. An encapsulation layer encloses ends of the gate layer, thereby defining gaps between ends of the insulator layer and the encapsulation layer. These gaps have a depth relative to the ends of the gate layer, with one end of the insulator layer proximate to a boundary between the first region and the third region and another end of the insulator layer proximate to a boundary between the second region and the third region. | 08-19-2010 |
Michael Edward Kellam, Glen Waverley AU
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20130199677 | MAGNESIUM-BASED ALLOY FOR WROUGHT APPLICATIONS - An improved magnesium-based alloy for wrought applications is disclosed, including a method of fabricating alloy sheet from said alloy. The improved magnesium-based alloy consists of: 0.5 to 4.0% by weight zinc; 0.02 to 0.70% by weight a rare earth element, or mixture of the same including gadolinium; and incidental impurities. The rare earth clement in some embodiments may be yttrium and/or gadolinium. In some embodiments the magnesium-based alloy may also consist of a grain refiner and in some embodiments the grain refiner may be zirconium. In combination, the inclusion of zinc and a rare earth element, into the magnesium alloy may have enhanced capacity for rolling workability, deep drawing at low temperatures and stretch formability at room temperature. The improved alloy may also exhibit increased tensile strength and formability while evincing a reduced tendency for tearing during preparation. | 08-08-2013 |
Paul Kellam, London GB
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20130261137 | Methods, Compounds and Compositions Relating to Activating a Latent Virus - The present invention relates to, inter alia, an anti-microtubule agent for use in a method of treating a subject having a latent virus, the method comprising: administering the anti-microtubule agent and an anti-viral agent to the subject. | 10-03-2013 |
20150057160 | PATHOGEN SCREENING - The present invention relates to methods of isolating pathogenic genomes from a clinical sample. | 02-26-2015 |