Napper
Andrew Napper, Salem, MA US
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20090306168 | SirT Inhibitors That Bind to NAD - Compound of formula (I) | 12-10-2009 |
Andrew Napper, Acton, MA US
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20090264410 | THERAPEUTIC COMPOUNDS AND USES THEREOF - Compounds of formula (I) are described herein | 10-22-2009 |
Andrew D. Napper, Chadds Ford, PA US
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20080261970 | Sufonamides and Uses Thereof - Compounds of formula (I), including methods of making and methods of using are described in formula (I). | 10-23-2008 |
20120010176 | UTROPHIN PROMOTER ACTIVITY UPREGULATION FOR THE TREATMENT OF MUSCULAR DYSTROPHY - Methods are provided for increasing utrophin promoter activity, utrophin expression or utrophin activity, and treating or reducing the symptoms of muscular dystrophy by administering to a subject in need thereof an effective amount of a composition comprising a utrophin promoter or activity upregulator. Muscular dystrophy includes but is not limited to Duchenne muscular dystrophy, Becker's muscular dystrophy, limb girdle muscular dystrophy, or a disease characterized by mutation or dysregulation of the dystrophin gene or an aberrant or dysfunctional dystrophin. | 01-12-2012 |
20140163029 | SirT INHIBITORS THAT BIND TO NAD - Compound of formula (I) | 06-12-2014 |
Carrie Napper, Gordonsville, VA US
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20140295099 | LIQUID COATING, COATED FILM AND PROCESS FOR COATING FILM - A system, a method, a device, an article of manufacture, a liquid coating, a computer program manufacturing a liquid coating, and a computer program for coating a film and making a coated film product for use with digital printers. | 10-02-2014 |
Catherine Elizabeth Napper, Witney GB
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20090137472 | CHIMERIC MHC PROTEIN AND OLIGOMER THEREOF - The invention concerns a oligomeric MHC complex comprising at least two chimeric proteins, said chimeric proteins comprising a first section derived from an MHC peptide chain or a functional part thereof and a second section comprising an oligomerising domain derived from an oligomer-forming coiled-coil protein, wherein formation of the oligomeric MHC complex occurs by oligomerisation at the oligomerising domain of the chimeric proteins, and wherein at least two of the first sections are derived from the same MHC peptide chain. The invention also concerns a chimeric protein comprising a first section derived from an MHC peptide chain or a functional part thereof and a second section comprising an oligomerising domain derived from an oligomer-forming coiled-coil protein. The invention further concerns a method of labeling and/or detecting mammalian T cells according to the specificity of their antigen receptor, by combining an oligomeric MHC complex according to the invention and a suspension or biological sample comprising T cells, and detecting the presence of specific binding of said complex and the T cells. Finally the invention concerns primers consisting of DNA sequences for genetic engineering of the above chimeric protein. | 05-28-2009 |
20150031566 | BIOTINYLATED MHC COMPLEXES AND THEIR USES - The invention demonstrates an improved choice of biotinylation peptide to be used in a combination or fusion with an MHC molecule for immobilizing or multimerising such MHC molecules for a variety of purposes. | 01-29-2015 |
David Napper, St. Catharines CA
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20120296751 | POINT OF SALE DEVICE FOR USE WITH A SHOPPING CART - A point of sale device for use with a shopping cart, the shopping cart having a basket for holding products, the basket having a bottom, and an upstanding sidewall extending from said bottom and defining open top. The point of sale device has a product detector for monitoring and validating the products in the basket, a control unit communicating with the product detector, the control unit having a user interface with a display screen, and an information detector communicating with the control unit for detecting product information and sending the product information to the control unit. The control unit communicates with the store's accounting/inventory system and has a calculator which calculates the cost of the products in the basket of the shopping cart using the product information and displays at least the cost of the products on the display screen. | 11-22-2012 |
David Napper, Aabenraa DK
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20080314760 | Use of an Anode For Elimination or Reduction of Microbial Impurities in Liquids. - The present invention relates to the use of an anode suitable for use in inter alia a reactor for elimination or reduction of microbial impurities from liquids, such as inter alia waste water and water intended for human or animal consumption. The anode comprises an expanded metal plate, preferably titanium, covered with a non-corrosive metal layer, preferably a platinum layer. The surface of the anode is endowed with dents, which enhances the electrochemical effect between the anode and the corresponding cathode and thereby enhances the microbial effect and at the same time reduces the energy required to obtain an efficient kill of the microorganisms, | 12-25-2008 |
David Napper, Ontario CA
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20130226651 | Order Processing for Remotely Ordered Goods - A method for fulfilling a plurality of orders for goods at a provider location comprises obtaining an arrival sequence estimate for each of a plurality of users indicating the sequence in which the users are expected to arrive, and organizing completed orders according to the arrival sequence estimate. The arrival sequence estimate may be obtained by ordering users according to their respective radial distances from a target, and may also be used to schedule processing of the orders. Alternatively, arrival estimates for when each of the users is expected to arrive may be used to schedule processing of the orders. A dynamic arrival estimate may be obtained based on an expected travel path toward the destination during a first trip portion comprising travel within a constrained travel path network, and based on radial distance from the destination during a second trip portion subsequent to the first trip portion. | 08-29-2013 |
David Napper, St. Catherines CA
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20140222623 | Order Processing for Remotely Ordered Goods - A computer-implemented method for processing of an order for goods received at an order processing system from a location-triggered communication through a networked mobile wireless telecommunication computing device. Responsive to the location-triggered communication, a signal is transmitted to commence processing the order for goods. If the mobile wireless telecommunication computing device requests, an item list of available items and corresponding processing times for each request could also be transmitted. The item list may form part of an application program installable on the mobile wireless telecommunication computing device. The location-triggered communication may include payment information. The method may also process payment information and transmit an order receipt to the mobile wireless telecommunication computing device. | 08-07-2014 |
Jeffrey Napper, Delft NL
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20150271203 | METHOD, SYSTEM, AND LOGIC FOR IN-BAND EXCHANGE OF META-INFORMATION - In an embodiment, a method is provided for enabling in-band data exchange between networks. The method can comprise receiving, by a first enveloping proxy located in the first network, at least one regular secure sockets layer (SSL) record for a SSL session established between a client and a server; receiving the data from a network element located in the first network; encoding the data into at least one custom SSL record; and transmitting the at least one regular SSL record and the at least one custom SSL record to an enveloping proxy. In another embodiment, a method can comprise receiving at least one regular secure sockets layer (SSL) record and at least one custom SSL record for a SSL session established between a client and a server; extracting the data from the at least one custom SSL; transmitting the at least one regular SSL record. | 09-24-2015 |
20150271204 | METHOD, SYSTEM, AND LOGIC FOR IN-BAND EXCHANGE OF META-INFORMATION - In an embodiment, a method is provided for enabling in-band data exchange between networks. The method can comprise receiving, by a first enveloping proxy located in the first network, at least one regular secure sockets layer (SSL) record for a SSL session established between a client and a server; receiving the data from a network element located in the first network; encoding the data into at least one custom SSL record; and transmitting the at least one regular SSL record and the at least one custom SSL record to an enveloping proxy. In another embodiment, a method can comprise receiving at least one regular secure sockets layer (SSL) record and at least one custom SSL record for a SSL session established between a client and a server; extracting the data from the at least one custom SSL; transmitting the at least one regular SSL record. | 09-24-2015 |
20150271205 | METHOD, SYSTEM, AND LOGIC FOR IN-BAND EXCHANGE OF META-INFORMATION - In an embodiment, a method is provided for enabling in-band data exchange between networks. The method can comprise receiving, by a first enveloping proxy located in the first network, at least one regular secure sockets layer (SSL) record for a SSL session established between a client and a server; receiving the data from a network element located in the first network; encoding the data into at least one custom SSL record; and transmitting the at least one regular SSL record and the at least one custom SSL record to an enveloping proxy. In another embodiment, a method can comprise receiving at least one regular secure sockets layer (SSL) record and at least one custom SSL record for a SSL session established between a client and a server; extracting the data from the at least one custom SSL; transmitting the at least one regular SSL record. | 09-24-2015 |
Johnathon Leigh Napper, Balmain AU
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20110182514 | METHOD OF DECODING CODING PATTERN HAVING SELF-ENCODED FORMAT - A method of decoding a coding pattern disposed on or in a substrate. The method comprises the steps of: (a) operatively positioning an optical reader relative to a surface of the substrate; (b) capturing an image of a portion of the coding pattern; (c) sampling and decoding a registration symbol contained in the imaged portion; (d) determining, using the decoded registration symbol, an encoding format; and (e) using the determined encoding format to sample and decode data symbols in the imaged portion. The coding pattern comprises a plurality of macrodots encoding data symbols and registration symbols, wherein each data symbol is represented by d macrodots, each of the d macrodots occupying a respective position from a plurality of predetermined possible positions p, the respective positions of the d macrodots representing one of a plurality of possible data values. Each registration symbol, or a set of the registration symbols, identifies an integer value of d and thereby the encoding format. | 07-28-2011 |
Jonathon Leigh Napper US
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20140093173 | Classifying a string formed from hand-written characters - A method of classifying a character string formed from a known number of hand-written characters is disclosed. The method starts by determining character probabilities for each hand-written character in the character string. Each character probability represents a likelihood of the respective hand-written character being a respective one of a plurality of predetermined characters. Each predetermined character has a respective character type. Character templates having the known number of characters are next identified. Each character template has a respective predetermined probability and represents a respective combination of character types. Character sequence probabilities corresponding to each of the character templates having the known number of characters are next determined. The character sequence probabilities are a function of the predetermined probability of the respective character template and the character probabilities of the hand-written character in the character string. The character string is classified as the sequence of characters having the highest character sequence probability. | 04-03-2014 |
Richard Charles Napper, Sydney AU
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20150190605 | POSITIVE AIRWAY PRESSURE DEVICE - A positive airway pressure (PAP) device for supplying a flow of breathable gas to a patient includes a flow generator configured to pressurize a flow of breathable gas and a humidifier configured to receive and humidify the pressurized flow of breathable gas from the flow generator. The PAP device also includes a power source. The flow generator, humidifier and power source are positioned so that heat generated by at least one of the flow generator and the power source is conveyed to water in the humidifier. | 07-09-2015 |
Richard Charles Napper, Wahroonga AU
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20100132708 | POSITIVE AIRWAY PRESSURE DEVICE - A positive airway pressure (PAP) device for supplying a flow of breathable gas to a patient includes a first housing; a flow generator provided in the first housing, the flow generator configured to generate a flow of breathable gas; a second housing configured to be connected to the first housing, the second housing including a channel having an inlet configured to receive the flow of breathable gas and an outlet configured to discharge the flow of breathable gas, wherein the first housing is provided on top of the second housing such that a footprint of the PAP device is not substantially increased beyond a footprint of the second housing. | 06-03-2010 |
20130247911 | POSITIVE AIRWAY PRESSURE DEVICE - A positive airway pressure (PAP) device for supplying a flow of breathable gas to a patient includes a first housing; a flow generator provided in the first housing, the flow generator configured to generate a flow of breathable gas; a second housing configured to be connected to the first housing, the second housing including a channel having an inlet configured to receive the flow of breathable gas and an outlet configured to discharge the flow of breathable gas, wherein the first housing is provided on top of the second housing such that a footprint of the PAP device is not substantially increased beyond a footprint of the second housing. | 09-26-2013 |
Scott Napper, Saskatoon CA
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20090280125 | Prion epitopes and methods of use thereof - Prion peptides comprising prion epitopes and fusions thereof, that display enhanced immunogenicity are described. Also described are methods of treating and diagnosing prion disease. | 11-12-2009 |
20130204536 | METHODS OF KINOME ANALYSIS - Method for analyzing phosphorylation data of a plurality of peptides are provided, the method comprising obtaining one or more datasets, each dataset comprising a phosphorylation signal intensity for each replicate of the plurality of peptides for a sample; transforming the phosphorylation signal intensity of each replicate of the plurality of peptides using a variance stabilizing transformation to provide a variance stabilized signal intensity for each replicate of the plurality of peptides; and identifying one or more peptides of the plurality of peptides that is/are consistently phosphorylated or consistently unphosphorylated. | 08-08-2013 |
20140303010 | Methods and Compositions for Species-Specific Kinome Microarrays - A method of preparing a species-specific phosphorylation site peptide array for a target organism comprising: a) selecting a plurality of known non-target organism (NTO) phosphorylation site sequences and cognate known NTO phosphorylation polypeptide sequences from one or more NTO, each of the known NTO phosphorylation site sequences comprising at least 5 residues and less than 30 residues; b) identifying a matching target organism (TO) phosphorylation site sequence and cognate TO phosphorylation polypeptide sequence for one or more of the known NTO phosphorylation site sequences; c) determining the matching TO phosphorylation site sequences that correspond to orthologue polypeptides of the cognate known NTO phosphorylation polypeptide sequences; d) selecting the matching TO phosphorylation site sequences determined to correspond to orthologue polypeptides for inclusion on the array; wherein the matching TO phosphorylation site sequences that correspond to orthologue polypeptides are determined by calculating, for each matching phosphorylation site sequence identified in b), a similarity value between the TO phosphorylation polypeptide sequence corresponding to the TO phosphorylation site sequence and a TO polypeptide sequence matching the cognate known NTO polypeptide sequence. | 10-09-2014 |
20150153354 | Methods and Compositions for Characterizing Phenotypes Using Kinome Analysis - Isolated peptides, arrays comprising a plurality of peptides and methods of use thereof are provided which can be used for identifying bee phenotypes and selecting bee lines with favourable characteristics. | 06-04-2015 |
Scott Kirk Napper, Saskatoon CA
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20100221272 | IMMUNOMODULATORY COMPOSITIONS AND METHODS FOR TREATING DISEASE WITH MODIFIED HOST DEFENSE PEPTIDES - Compositions and methods are provided for modulating an immune response in a vertebrate subject. Compositions and methods can comprise administering a modified host defense peptide to the vertebrate subject in an amount effective to activate the immune response in the vertebrate subject, wherein the modified host defense peptide is inverted in amino acid sequence from an amino terminus to a carboxy terminus or modified to one or more D-amino acids, or both modifications, when compared to a host defense peptide. Compositions and methods are provided which comprise administering a modified host defense peptide to the vertebrate subject in an amount effective to modify an immune response in the vertebrate subject. | 09-02-2010 |