Patent application number | Description | Published |
20100093994 | REPARATION METHOD OF AN AMINO LINKER OLIGONUCLEOTIDES AND LABELED-LINKER OLIGONUCLEOTIDE THEREFROM - A method for preparing amino linker oligonucleotides is provided, wherein an amino protecting group is efficiently removed from the amino linker oligonucleotides protected by the protecting group, and thereby achieving a high yield of the amino linker oligonucleotides. | 04-15-2010 |
20100317723 | Nucleolin Specific Aptamer and Use thereof - Improved G-rich oligonucleotide (GRO) aptamers specific to nucleolin, a method of preparing the aptamers, and a use of the aptamers for diagnosing and/or treating a nucleolin-associated disease, are provided. | 12-16-2010 |
20110262922 | APTAMER SANDWICH ASSAYS - The present invention provides methods for identifying the plurality of aptamers that bind to different sites of a target molecule and methods for using the same, for example, in sandwich assays. In particular, the plurality of aptamers binding to different sites of the target molecules is identified from a library of aptamers identified from the same SELEX process. | 10-27-2011 |
20130039918 | Pharmaceutical Composition Using Connective-tissue Growth Factor - This disclosure relates to an angiogenesis-related pharmaceutical composition using connective tissue growth factor, more particularly to a pharmaceutical composition for promoting angiogenesis containing the connective tissue growth factor or a pharmaceutical composition for inhibiting angiogenesis containing at least one selected from the group consisting of polypeptide, antibody and a compound binding to connective tissue growth factor. The fragment of connective tissue growth factor protein, which was found out in the present invention, is a binding region to FPRL1, effectively induces FPRL1-specific ERK phosphorylation, activates FPRL1 to increase intracellular Ca | 02-14-2013 |
20130059292 | METHOD OF DETECTING A TARGET USING APTAMER-MEDIATED PROTEIN PRECIPITATION ASSAY - The present invention relates to a method and detection kit for determining a presence of one or more proteins using aptamer-mediated pull-down assays. Specifically, a reproducible a protein precipitation (Co-AP/AP) method is provided to identify physiologically relevant protein-protein interactions by using target protein-specific aptamers, and to confirm its superior performance over antibody based protein precipitation (Co-IP/IP) methods in terms of its protein pull-down performance. | 03-07-2013 |
20140093886 | Method of diagnosing cancer using a nucleolin specific aptamer - Improved G-rich oligonucleotide (GRO) aptamers specific to nucleolin, a method of preparing the aptamers, and a use of the aptamers for diagnosing and/or treating a nucleolin-associated disease, are provided. | 04-03-2014 |
20140213636 | Method of treating hyperproliferation of cells using a nucleolin specific aptamer - Improved G-rich oligonucleotide (GRO) aptamers specific to nucleolin, a method of preparing the aptamers, and a use of the aptamers for diagnosing and/or treating a nucleolin-associated disease, are provided. | 07-31-2014 |
Patent application number | Description | Published |
20080207490 | Glucose Uptake Modulator and Method for Treating Diabetes or Diabetic Complications - The present invention relates to an glucose uptake modulator, a pharmaceutical composition comprising the glucose uptake modulator, and a method of treating a diabetes or diabetic complications in a mammal in need thereof, which comprises administering to said mammal an effecting amount of a glucose uptake modulator. | 08-28-2008 |
20080274978 | Peptides That Antagonize Fpr Class Receptor Mediated Signaling - The present application discloses W-rich peptide that is useful for inhibiting FPR class receptor activity. | 11-06-2008 |
20090312250 | EPIDERMAL GROWTH FACTOR INCREASING INSULIN SECRETION AND LOWERING BLOOD GLUCOSE - The present inventors show that a brief exposure to EGF stimulates insulin secretion glucose-independently via a Ca2+ influx- and PLD2-dependent mechanism. Furthermore, the present invention shows that EGF is a novel secretagogue that lowers plasma glucose levels in normal and diabetic mice, suggesting the potential for EGF treatment in diabetes. | 12-17-2009 |
20100261245 | LONG ACTING FORMULATION OF BIOPHARMACEUTICAL - The invention relates to a long-acting formulation of biopharmaceutical, more specifically an aptamer therapeutics. A branched PEGylated aptamer or a hyaluronic acid (HA) derivative of which degradation in vivo is regulated is linked by the bioconjugation with biopharmaceutical to produce the long-action formulation. | 10-14-2010 |
20110111477 | LONG ACTING FORMULATION OF BIOPHARMACEUTICAL - The invention relates to a long-acting formulation of biopharmaceutical, more specifically an aptamer therapeutics. A branched PEGylated aptamer or a hyaluronic acid (HA) derivative of which degradation in vivo is regulated is linked by the bioconjugation with biopharmaceutical to produce the long-action formulation. | 05-12-2011 |
Patent application number | Description | Published |
20080228945 | METHOD AND APPARATUS FOR SYNCHRONIZING FEED INFORMATION - A method and apparatus for synchronizing feed information are provided. A podcasting client includes a synchronization-processing unit which synchronizes first feed information acquired from a connected device with pre-stored second feed information, and a communication interface which transmits feed information of content that is podcast based on the synchronized feed information to the connected device. | 09-18-2008 |
20080301173 | METHOD AND APPARATUS FOR GENERATING PLAYLIST OF MEDIA CONTENT AND METHOD AND APPARATUS FOR PLAYING MEDIA CONTENT - Provided are a method and apparatus for generating a playlist of media content and a method and apparatus for playing media content. The method of generating a playlist of media content includes providing a user interface for setting a playlist while media content is being played and generating a playlist of media content to be played according to playlist settings set through the user interface. | 12-04-2008 |
20090073161 | METHOD AND APPARATUS FOR PROVIDING SLIDE SHOW BY USING PLURALITY OF IMAGES - A method of providing a slide show includes selecting one of a plurality of images in which geographic position information is set, marking a plurality of positions corresponding to the plurality of images on a map based on geographic position information and outputting the map, setting an image search range on the map based on a position on the map, which corresponds to the selected image, and providing the slide show by using images corresponding to positions on the map, which belong to the set image search range. | 03-19-2009 |
20100036812 | Method and apparatus for generating and providing relevant information related to multimedia content - A method of generating relevant information related to multimedia content at a client that reproduces the multimedia content includes accessing a blog service connected to the client, selecting the first content of the multimedia content, for which relevant information is to be generated, by using the blog service, generating the relevant information using a template according to the type of the relevant information generated with respect to the first content, and transmitting the generated relevant information to a server. | 02-11-2010 |
20100057692 | Method and apparatus for collecting and providing information of interest to user regarding multimedia content - A method of collecting information of interest to a user regarding multimedia content is described. The method may include receiving first content about the information of interest to the user among the multimedia content, collecting metadata of the first content by using a uniform resource identifier (URI) of the first content, extracting at least one first information object including a schema according to a search category from the metadata, and storing the first information object in a first database. | 03-04-2010 |
20110171968 | METHOD AND APPARATUS FOR LOCATING A MOBILE TERMINAL USING RECEIVED MESSAGES - A method and apparatus for locating a mobile terminal by use of messages received to the mobile terminal are provided. The mobile terminal locating method may include creating at least one location related candidate for the mobile terminal by use of a message that is received to the mobile terminal, and determining a location of the mobile terminal by matching the created location related candidate to stored place information. The current location of the mobile terminal may be recognized by simply analyzing the received messages without the need for installation of additional device on the mobile terminal. | 07-14-2011 |
20110185038 | APPARATUS AND METHOD FOR PROVIDING A TERMINAL WEB SERVICE - An apparatus and method for providing a terminal web service capable of being associated with data and/or native operations of a terminal while using a rich internet application are provided. The terminal apparatus includes a web application providing unit and a terminal web service providing unit. The web application providing unit discovers a terminal web service control script, which performs control to achieve association with respect to a terminal web service provided by the terminal apparatus, by executing a client script received from an external web server and to generate a hypertext transport protocol (HTTP) request message for requesting the terminal web service by use of the terminal web service control script. The terminal web service providing unit is configured to, upon reception of the HTTP request message, provide the terminal web service by sending the web application providing unit a HTTP reply message for providing reply information by the terminal web service. | 07-28-2011 |
20110252065 | APPARATUS AND METHOD FOR SEMANTIC-BASED SEARCH AND SEMANTIC METADATA PROVIDING SERVER AND METHOD OF OPERATING THE SAME - A semantic-based searching apparatus and method which can search for desired information from various types of media using associative properties of search target objects are provided. The semantic-based searching apparatus stores an associative search structure that previously stores a semantic index. The associative search structure is to obtain a final search object corresponding to an input search query. The semantic index configuration includes feature metadata used to identify a specific object, semantic entity metadata to indicate semantic entities corresponding to the feature metadata, and semantic relation metadata to indicate a relation between the semantic entities. The semantic-based searching apparatus uses semantic metadata stored in conformity with the semantic index configuration, the semantic index, and the associative search structure to generate a search result corresponding to the input search query. | 10-13-2011 |