Aaron D.
Aaron D. Civil, Rochester, MN US
Patent application number | Description | Published |
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20130030862 | TREND-BASED TARGET SETTING FOR PROCESS CONTROL - Determining a suitable target for an entity (such as a product) in a process control environment, based on observed process control data. A preferred embodiment organizes data in a hierarchical structure designed for automating the target-setting process; derives target “yardsticks” for various components based on this data structure; employs techniques to estimate proportions using sample-size-based trimming in conjunction with bias-correction techniques (where appropriate); and derives targets based on combining yardsticks and confidence regions for parameters that characterize component quality | 01-31-2013 |
20130030863 | TREND-BASED TARGET SETTING FOR PROCESS CONTROL - Determining a suitable target for an entity (such as a product) in a process control environment, based on observed process control data. A preferred embodiment organizes data in a hierarchical structure designed for automating the target-setting process; derives target “yardsticks” for various components based on this data structure; employs techniques to estimate proportions using sample-size-based trimming in conjunction with bias-correction techniques (where appropriate); and derives targets based on combining yardsticks and confidence regions for parameters that characterize component quality | 01-31-2013 |
20130041625 | Advanced Statistical Detection of Emerging Trends - Advanced statistical detection of emerging trends in a process is disclosed, based on a Repeated Weighted Geometric Cumulative Sum analysis, which may be combined with time window-based estimation of proportions and related thresholds. Threshold derivation and significance computation is based on parallel simulation runs with power-exponential tail approximations. A battery of tests using the statistical theory of sequential analysis and change-point theory in combination with targets is used to evaluate non-conforming conditions in a process. Trends in fall-out rates are detected based on non-time-to-failure data that corresponds to counts of failures in consecutive time periods, with possibility of delayed input. | 02-14-2013 |
20130041626 | Hybrid Analysis of Emerging Trends for Process Control - An asymmetric approach is used for evaluating process control data, whereby one approach is used for determining entry into the emerging life cycle phase (i.e., presence of a new defect) and a different approach is used for detecting entry into the other life cycle phases such as cresting and recovering. An evidence curve is created from observed instance data for a particular defect, and the slope of this evidence curve is analyzed programmatically by applying one or more tests, in combination with sequential time-reversed estimation, to determine return-to-normal conditions with a desired level of confidence. | 02-14-2013 |
20130041709 | Hybrid Analysis of Emerging Trends for Process Control - An asymmetric approach is used for evaluating process control data, whereby one approach is used for determining entry into the emerging life cycle phase (i.e., presence of a new defect) and a different approach is used for detecting entry into the other life cycle phases such as cresting and recovering. An evidence curve is created from observed instance data for a particular defect, and the slope of this evidence curve is analyzed programmatically by applying one or more tests, in combination with sequential time-reversed estimation, to determine return-to-normal conditions with a desired level of confidence. | 02-14-2013 |
20130041710 | Advanced Statistical Detection of Emerging Trends - Advanced statistical detection of emerging trends in a process is disclosed, based on a Repeated Weighted Geometric Cumulative Sum analysis, which may be combined with time window-based estimation of proportions and related thresholds. Threshold derivation and significance computation is based on parallel simulation runs with power-exponential tail approximations. A battery of tests using the statistical theory of sequential analysis and change-point theory in combination with targets is used to evaluate non-conforming conditions in a process. Trends in fall-out rates are detected based on non-time-to-failure data that corresponds to counts of failures in consecutive time periods, with possibility of delayed input. | 02-14-2013 |
Aaron D. Cobabe, Syracuse, UT US
Patent application number | Description | Published |
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20080222822 | CLEANING APPARATUS WITH RECIPROCATING BRUSH HEAD - A cleaning apparatus includes an elongated housing bounding a chamber with a motor disposed therein. A drive shaft is at least partially disposed within the chamber of the housing, the drive shaft being coupled with the motor such that during selective operation of the motor the drive shaft is rotated continuously. A head assembly includes an elongated head housing having a head drive shaft and a brush head mounted thereon. The head assembly is adapted to be selectively coupled with the body assembly so that the body drive shaft is coupled with the head drive shaft. | 09-18-2008 |
20100017978 | CLEANING APPARATUS WITH RECIPROCATING BRUSH HEAD - A cleaning apparatus includes an elongated housing bounding a chamber with a motor disposed therein. A drive shaft is at least partially disposed within the chamber of the housing, the drive shaft being coupled with the motor such that during selective operation of the motor the drive shaft is rotated. A head assembly includes an elongated head housing having a head drive shaft and a brush head mounted thereon. The head assembly is adapted to be selectively coupled with the body assembly so that the body drive shaft is coupled with the head drive shaft. | 01-28-2010 |
20110047728 | CLEANING APPARATUS WITH RECIPROCATING BRUSH HEAD - A cleaning apparatus includes an elongated housing bounding a chamber with a motor disposed therein. A drive shaft is at least partially disposed within the chamber of the housing, the drive shaft being coupled with the motor such that during selective operation of the motor the drive shaft is rotated. A head assembly includes an elongated head housing having a head drive shaft and a brush head mounted thereon. The head assembly is adapted to be selectively coupled with the body assembly so that the body drive shaft is coupled with the head drive shaft. | 03-03-2011 |
20120192366 | CLEANING APPARATUS WITH ROTATING AND DETACHABLE BRUSH HEAD - A cleaning apparatus includes an elongated housing bounding a chamber with a motor disposed therein. A drive shaft is at least partially disposed within the chamber of the housing, the drive shaft being coupled with the motor such that during selective operation of the motor the drive shaft is rotated continuously. A brush head having a scrubbing element is removably coupled with the drive shaft such that rotation of the drive shaft facilitates rotation of the brush head. | 08-02-2012 |
Aaron D. Cobabe, Syarcuse, UT US
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20120216831 | CLEANING APPARATUS WITH BRUSH HEAD DISENGAGER - A cleaning apparatus includes an elongated housing bounding a chamber with a motor disposed therein. A drive shaft is at least partially disposed within the chamber of the housing, the drive shaft being coupled with the motor such that during selective operation of the motor the drive shaft is rotated. A hub having a rotational axis about which the hub rotates is coupled with the drive shaft such that rotation of the drive shaft facilitates rotation of the hub. A cleaning head is removably coupled with the hub such that rotation of the hub causes rotation of the cleaning head. A disengaging system is movable between a first position where the cleaning head is securely engaged to the hub and a second position where the cleaning head is freely removable from the hub. | 08-30-2012 |
Aaron D. Davies, Portland, OR US
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20150180965 | METHOD, DEVICE, AND SYSTEM FOR AD-HOC RESOURCE SELECTION - A method, device, and system for selecting one or more devices and users to capture and share images of an event with other users includes establishing one or more ad-hoc groups with a resource management server. The resource management server communicates with one or more computing devices over a network to assign the computing devices to an ad-hoc group as a function of one or more users requesting to receive images captured at an event. For each ad-hoc group, the resource management server selects a device and a user to capture images of the event, which are distributed to the one or more users. Additionally, the computing devices may establish an ad-hoc group without the resource management server. A computing device of the ad-hoc group is selected to capture images of the event, which are distributed to users of the ad-hoc group through an ad-hoc network. | 06-25-2015 |
Aaron D. Gitler, Philadelphia, PA US
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20090099069 | MODULATORS OF ALPHA-SYNUCLEIN TOXICITY - Disclosed are compositions and methods for modulating expression of genes that function at the step of ER of Golgi trafficking. Compounds that modulate expression of these genes of activity of the encoded proteins can be used to inhibit alpha-synuclein mediated toxicity and used to threat of prevent synucleinopathies such as Parkinson's disease. Also disclosed are methods of identifying inhibitors of alpha-synuclein mediated toxicity. | 04-16-2009 |
20110053857 | YEAST CELLS EXPRESSING TAR DNA-BINDING PROTEIN 43 AND USES THEREFOR - Disclosed are yeast cells expressing TAR DNA-binding protein 43 (TDP-43) and methods of screening yeast cells to identify compounds that prevent or suppress TDP-43-induced toxicity, compounds that inhibit the formation or maintenance of cytoplasmic inclusions of TDP-43, genetic suppressors or enhancers of TDP-43-induced toxicity, and genetic suppressors or enhancers of the formation or maintenance of cytoplasmic inclusions of TDP-43. Compounds identified by such screens can be used to treat or prevent TDP-43 proteinopathies such as frontotemporal lobar degeneration or amyotrophic lateral sclerosis. | 03-03-2011 |
20110064722 | MODULATORS OF ALPHA-SYNUCLEIN TOXICITY - Disclosed are genes that, when overexpressed in cells expressing alpha-synuclein, either suppress or enhance alpha-synuclein mediated cellular toxicity. Compounds that modulate expression of these genes or activity of the encoded proteins can be used to inhibit alpha-synuclein mediated toxicity and used to treat or prevent synucleinopathies such as Parkinson's disease. Also disclosed are methods of identifying inhibitors of alpha-synuclein mediated toxicity. | 03-17-2011 |
20110142789 | Compositions and Methods for the Diagnosis and Treatment of Amyotrophic Lateral Sclerosis - Compositions and methods for diagnosis and treatment of ALS are provided. | 06-16-2011 |
20130244903 | MODULATORS OF ALPHA-SYNUCLEIN TOXICITY - Disclosed are compositions and methods for modulating expression of genes that function at the step of ER to Golgi trafficking. Compounds that modulate expression of these genes or activity of the encoded proteins can be used to inhibit alpha-synuclein mediated toxicity and used to treat or prevent synucleinopathies such as Parkinson's disease. Also disclosed are methods of identifying inhibitors of alpha-synuclein mediated toxicity. | 09-19-2013 |
20140051091 | MODULATORS OF ALPHA-SYNUCLEIN TOXICITY - Disclosed are genes that, when overexpressed in cells expressing alpha-synuclein, either suppress or enhance alpha-synuclein mediated cellular toxicity. Compounds that modulate expression of these genes or activity of the encoded proteins can be used to inhibit alpha-synuclein mediated toxicity and used to treat or prevent synucleinopathies such as Parkinson's disease. Also disclosed are methods of identifying inhibitors of alpha-synuclein mediated toxicity. | 02-20-2014 |
Aaron D. Gitler, Quincy, MA US
Patent application number | Description | Published |
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20090304664 | MODULATORS OF ALPHA-SYNUCLEIN TOXICITY - Disclosed are genes that, when overexpressed in cells expressing alpha-synuclein, either suppress or enhance alpha-synuclein mediated cellular toxicity. Compounds that modulate expression of these genes or activity of the encoded proteins can be used to inhibit alpha-synuclein mediated toxicity and used to treat or prevent synucleinopathies such as Parkinson's disease. Also disclosed are methods of identifying inhibitors of alpha-synuclein mediated toxicity. | 12-10-2009 |
Aaron D. Gitler, Foster City, CA US
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20120237499 | Modulators of TDP-43 Mediated Toxicity and Methods of Use Thereof for Identifying Agents Having Efficacy for the Treatment and Prevention of Proteinopathies - Compositions and methods are disclosed for identifying agents useful for the treatment of proteinopathies. | 09-20-2012 |
20130059757 | Novel Gene Targets Associated with Amyotrophic Lateral Sclerosis and Methods of Use Thereof - Compositions and methods for diagnosis and treatment of ALS are provided. | 03-07-2013 |
20150252424 | Novel Gene Targets Associated with Amyotrophic Lateral Sclerosis and Methods of Use Thereof - Novel gene targets and methods of use thereof for the diagnosis and treatment of Amyotrophic Lateral Sclerosis are provided. | 09-10-2015 |
20160046933 | MODULATORS OF ALPHA-SYNUCLEIN TOXICITY - Disclosed are genes that, when overexpressed in cells expressing alpha-synuclein, either suppress or enhance alpha-synuclein mediated cellular toxicity. Compounds that modulate expression of these genes or activity of the encoded proteins can be used to inhibit alpha-synuclein mediated toxicity and used to treat or prevent synucleinopathies such as Parkinson's disease. Also disclosed are methods of identifying inhibitors of alpha-synuclein mediated toxicity. | 02-18-2016 |
Aaron D. James, Laguna Hills, CA US
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20160047147 | AUTOMOTIVE DOOR HINGE SAFETY LOCK - A door lock device including a hinged pivotal detent arm formed with a detent engageable with a lock pin to hold the door in an open position and a latch operative in response to an object in a doorway to latch the pin device in the detent. | 02-18-2016 |
Aaron D. Laposky, Gaithersburg, MD US
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20120231022 | GLP-1 RECEPTOR AGONIST COMPOUNDS FOR SLEEP ENHANCEMENT - The disclosure provides, among other things, the use of GLP-1 receptor agonist compounds to enhance sleep, increase the duration and/or intensity of non-rapid eye movement (NREM) sleep, treat NREM sleep disorders, and to treat circadian rhythm sleep disorders. The GLP-1 receptor agonist compounds may be exendins, exendin analogs, GLP-1(7-37), GLP-1(7-37) analogs (e.g., GLP-1(7-36)-NH | 09-13-2012 |
Aaron D. Lilak, Beaverton, OR US
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20130320455 | SEMICONDUCTOR DEVICE WITH ISOLATED BODY PORTION - Semiconductor devices with isolated body portions are described. For example, a semiconductor structure includes a semiconductor body disposed above a semiconductor substrate. The semiconductor body includes a channel region and a pair of source and drain regions on either side of the channel region. An isolation pedestal is disposed between the semiconductor body and the semiconductor substrate. A gate electrode stack at least partially surrounds a portion of the channel region of the semiconductor body. | 12-05-2013 |
Aaron D. Mueller, Phoenix, AZ US
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20130032567 | BOTTLE ADORNMENT DEVICE - A bottle adornment device includes a clamp assembly having a form portion and a clamp portion engaging the form portion. A bottle engaging element is carried between the form portion and the clamp portion, and a decorative item carried by the form portion. | 02-07-2013 |
Aaron D. Pailes, Acton, MA US
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20090268871 | X-Ray Inspection with Contemporaneous and Proximal Transmission and Backscatter Imaging - An X-ray imaging inspection system for bags and packages. Transmission imaging is performed using a fan beam and a segmented detector, while scatter imaging is performed with a scanned pencil beam, with both beams active simultaneously. Cross-talk between the beams is mitigated by a combination of shielding, scatter detector design, positioning and orientation, and image processing. Image processing subtracts the measured radiation scattered from the transmission beam into the scatter detectors, reducing cross-talk | 10-29-2009 |
20120093288 | Remotely-Aligned Arcuate Detector Array for High Energy X-ray Imaging - A scanning system and methods for inspecting contents of a container. High-energy penetrating radiation collimated into a fan beam illuminates an inspected container from one side, while a plurality of detector plates are disposed on the opposite side of the container. Each detector plate has a plurality of detector modules, each of which, in turn, is disposed on a remotely activated alignment and has multiple detector elements. A controller governs the orientation of each of the plurality of detector plates based at least on the detector signal generated by its detector elements such that each detector element of each detector module of each detector plate may be aligned to within a specified fraction of the transverse dimension of the fan beam as measured at the exit slot. | 04-19-2012 |
20130230140 | Methods for High Energy X-ray Imaging Using Remotely-Aligned Arcuate Detector Array - Methods for inspecting contents of a container. High-energy penetrating radiation collimated into a fan beam illuminates an inspected container from one side, while a plurality of detector plates are disposed on the opposite side of the container. Each detector plate has a plurality of detector modules, each of which, in turn, is disposed on a remotely activated alignment and has multiple detector elements. A controller governs the orientation of each of the plurality of detector plates based at least on the detector signal generated by its detector elements such that each detector element of each detector module of each detector plate may be aligned to within a specified fraction of the transverse dimension of the fan beam as measured at the exit slot. | 09-05-2013 |
Aaron D. Parecki, Portland, OR US
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20130267253 | TRIGGER ZONES AND DWELL TIME ANALYTICS - Certain embodiments of the invention related to a method of receiving and processing trigger zone and geo-trigger content on a computing device. Trigger zones can be relevant to a current geographic position of the computing device and can be characterized by a time-based boundary and one or more requirements to be satisfied to trigger an event. The computing device can evaluate trigger zones to determine if one the one or more requirements are satisfied and trigger an trigger event if confirmed. In some embodiments, a server computer can generate a dwell-time trigger zone based on an amount of time a computing device spends at a geographic location. The dwell time trigger zone can include trigger zone data corresponding to commercial aspects particular to the geographic location. The server computer can be configured to send the trigger zone and trigger zone data to the computing device for processing. | 10-10-2013 |
20140059695 | SYSTEMS AND METHODS FOR MANAGING LOCATION DATA AND PROVIDING A PRIVACY FRAMEWORK - A computer-implemented method includes providing a user interface on an internet-protocol (IP) connected mobile device, the user interface configured to receive a user input corresponding to one or more data privacy parameters for geo-location data, and controlling a transferring of geo-location data to and from each of a plurality of mobile applications on the mobile device based on the user input. A change in one or more of the data privacy parameters can change how geo-location data is provided to each of the plurality of applications and can affect location data accuracy, location data reporting frequency, geo-functions, and more. The user interface can be configured to allow a user to view, manage, and delete a personal location history. Furthermore, one or more profiles can be associated with one or more of the plurality of mobile applications, where each of the one or more profiles is assigned individual data privacy parameters. | 02-27-2014 |
Aaron D. Pesnell, Belle Mead, NJ US
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20130149343 | Hemostatic Bioabsorbable Device with Polyethylene Glycol Binder - A hemostatic pad comprising a bioabsorbable scaffolding material; a lyophilized thrombin powder, a lyophilized fibrinogen powder, and a meltable binder powder, with all powders disposed on the bioabsorbable scaffolding material. A meltable binder such as PEG bonds the lyophilized thrombin powder and the lyophilized fibrinogen powder to the bioabsorbable scaffolding material for improved friability, wettability and performance in a use, such as for hemostatic treatment or sealing at a wound site. | 06-13-2013 |
20150238366 | Hemostatic Bioabsorbable Device with Polyethylene Glycol Binder - A hemostatic pad comprising a bioabsorbable scaffolding material; a lyophilized thrombin powder, a lyophilized fibrinogen powder, and a meltable binder powder, with all powders disposed on the bioabsorbable scaffolding material. A meltable binder such as PEG bonds the lyophilized thrombin powder and the lyophilized fibrinogen powder to the bioabsorbable scaffolding material for improved friability, wettability and performance in a use, such as for hemostatic treatment or sealing at a wound site. | 08-27-2015 |
Aaron D. Pesnell, Cherry Hill, NJ US
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20100131037 | RADIOPAQUE POLYMERIC STENTS - The present invention relates to polymeric medical devices such as stents. More particularly the polymeric compositions disclosed herein comprise halogen-containing, tyrosine-derived diphenols, optionally in conjunction with other groups, such as dicarboxylic acids and/or poly(alkylene oxides), such that the medical devices made from these polymeric compositions are bioresorbable and inherently radiopaque, and exhibit physicomechanical properties consistent with the intended uses of such devices. | 05-27-2010 |
Aaron D. Pokowski, St. Clair Shores, MI US
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20100007156 | Glove box striker with box clip attachment feature - The present invention provides a striker with a box clip feature. The striker may be mounted to a support structure for engagement with a latch mechanism. The striker may include a body for mounting to a support structure, such as an instrument panel in a vehicle. The striker may include a latch bar capable of engaging the latch mechanism. The striker may also include a locating feature that may aid in alignment within the support structure for quick assembly. The box clip feature may include an aperture that is capable of connecting said body to the support structure. | 01-14-2010 |
20130266394 | QUICKIE STUD ASSEMBLY - A stud assembly may be used to secure one item, such as a panel, to a second item, such as a second panel. The stud assembly may include a fastener, a first clip having a fastener portion and a retaining portion, the retaining portion having at least one aperture, where the first clip is attached to the fastener at the fastener portion, and a second clip attached to the fastener and spaced from the fastener portion of the first clip, the second clip having at least one tab, where the tab engages the aperture to secure the first clip to the second clip. | 10-10-2013 |
Aaron D. Schilpp, Appleton, WI US
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20120035563 | Absorbent Articles with Intricate Graphics - Absorbent articles are disclosed that have been printed with active graphics alone or in combination with permanent graphics to create a wetness indicator. Different active graphic compositions and/or permanent graphic compositions are combined so as to make the wetness indicator very prominent on the article. In addition, when the absorbent article is wetted, the active graphics undergo a change that is easily noticed by the wearer or the caregiver for the wearer. In one embodiment, for instance, active graphics are positioned within a distinctive frame. The frame focuses a person's attention onto the active graphics. The active graphics fill most of the surface area of the frame such that when the absorbent article is wetted, a clearly noticeable change occurs. | 02-09-2012 |
Aaron D. Stephens, Waterford, MI US
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20150323858 | HAND-WEARABLE CAMERA HARNESS AND METHOD OF ASSEMBLING THE HAND-WEARABLE CAMERA HARNESS - A hand-wearable camera harness is provided. The harness includes a plate member and a first aperture extending therethrough. The plate member has a first surface and a ring-shaped mounting portion fixedly coupled to the first surface. The ring-shaped mounting portion extends outwardly from the first surface and further extends circumferentially around the first aperture. The ring-shaped mounting portion has a top surface with a first plurality of grooves extending therein. The hand-wearable camera harness further includes a rotatable mounting bracket having a substantially circular-shaped base and at least first and second extension portions. The substantially circular-shaped base has a bottom surface with a second plurality of grooves extending therein. | 11-12-2015 |
Aaron D. Tward, Boston, MA US
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20130171124 | Compositions And Methods Of Treating Head And Neck Cancer - The present invention provides methods related to the treatment of head and neck squamous cell carcinoma (HNSCC) and its associated premalignant lesions. In particular, the invention features methods which may specifically target HNSCC-associated genes and alter gene expression to treat or alleviate a symptom of HNSCC, or its related premalignant lesions. These methods may involve decreasing the function of an HNSCC-associated gene with aberrant gain-of-function; or increasing the function of an HNSCC-associated gene with aberrant loss-of-function. | 07-04-2013 |