Hepperle
Jens Hepperle, Koln DE
Patent application number | Description | Published |
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20090148501 | PROCESS FOR THE PREPARATION OF AROMATIZED CHEWING FOAMS FOR COSMETIC PRODUCTS - The invention relates to a process for the preparation of novel aromatized chewing foams for the oral care sector based on polyurethane-polyureas and aromatizing compositions | 06-11-2009 |
20110124773 | PROCESS FOR CONTINUOUSLY PRODUCING THERMOPLASTICALLY PROCESSABLE POLYURETHANES - The invention relates to a process for continuously producing thermoplastically processable polyurethanes with improved softening behaviour in a sequence of static mixers. | 05-26-2011 |
20120116030 | PROCESS FOR CONTINUOUSLY PRODUCING THERMOPLASTICALLY PROCESSABLE POLYURETHANES - The invention relates to a process for continuously producing thermoplastically processable polyurethanes in a recycle reactor with flexibly adjustable mixing conditions. | 05-10-2012 |
20120120756 | MODULAR MIXER - The invention relates to modular mixers for applications in modular microprocess technology. | 05-17-2012 |
20120244201 | PROCESS FOR THE PREPARATION OF AROMATIZED CHEWING FOAMS FOR COSMETIC PRODUCTS - The invention relates to a process for the preparation of novel aromatized chewing foams for the oral care sector based on polyurethane-polyureas and aromatizing compositions. | 09-27-2012 |
20130215710 | DEVICE AND METHOD FOR GAS DISPERSION - The invention relates to a device for dispersing gas into a liquid. The devise has a number n of successive zones Z | 08-22-2013 |
Jens Hepperle, Koeln DE
Patent application number | Description | Published |
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20110215499 | EXTRUSION NOZZLE FOR POLYMERS - The invention relates to an improved die for the extrusion of melt strands of viscoelastic masses, and in particular to polymers and mixtures of polymers with other substances (such as solids, liquids or other polymers), where the use thereof avoids the formation of deposits in the region of the die. | 09-08-2011 |
Michael E. Hepperle, Kreuzlingen CH
Patent application number | Description | Published |
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20100323953 | MACROCYCLIC HEPATITIS C PROTEASE INHIBITORS - The present invention provides novel macrocyclic compounds that mimic peptide substrates of the hepatitis C viral protease and inhibit the viral protease, more particularly as inhibitors of the NS3 serine protease from hepatitis C virus. Methods for synthesis of the compounds are also provided. The compounds find utility as antiviral agents directed at hepatitis C. The invention further provides methods of employing such inhibitors, alone or in combination with other therapeutic agents, to treat hepatitis C infection in a subject in need of such treatment. | 12-23-2010 |
Michael E. Hepperle, San Diego, CA US
Patent application number | Description | Published |
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20090304631 | HEPATITIS C SERINE PROTEASE INHIBITORS AND USES THEREFOR - The invention provides compounds that inhibit a viral protease enzyme of the hepatitis C virus (HCV). The compounds are adapted for treatment of a HCV infection in a patient with the disease. The compounds include analogs of tripeptides and tetrapeptides that resemble the viral protease substrate. The invention also provides pharmaceutical compositions and combinations, methods of preparation of the compounds, and methods of treatment of patients afflicted with HCV using the compounds. | 12-10-2009 |
20090325889 | HEPATITIS C SERINE PROTEASE INHIBITORS AND USES THEREFOR - The present invention provides novel compounds which mimic peptides with a C-terminal penultimate proline, such compounds being useful as protease inhibitors, particularly as inhibitors of serine proteases, and more particularly as inhibitors of the NS3 serine protease from hepatitis C. The compounds find utility as antiviral agents directed at hepatitis C. The invention further provides methods of employing such inhibitors, alone or in combination with other therapeutic agents, to treat hepatitis C infection in a subject in need of such treatment. | 12-31-2009 |
20100093713 | BETA-CARBOLINES USEFUL FOR TREATING INFLAMMATORY DISEASE - This invention provides beta-carboline compounds of formula | 04-15-2010 |
20100120716 | MACROCYCLIC HEPATITIS C SERINE PROTEASE INHIBITORS AND USES THEREFOR - Macrocyclic inhibitors of Hepatitis C protease are provided, the inhibitors including a boronic acid or ester group, a macrocyclic ring of about 13 to 25 atoms including at least two amide linkages, a proline-analogous group, and a connecting segment joining moieties on either side of the proline-analogous group. Methods of making the HCV protease-inhibitory compounds, methods of using the compounds, formulations of the compounds, and pharmaceutical combinations including the compounds, are provided. | 05-13-2010 |
20100311715 | ALPHA CARBOLINES AND USES THEREOF - This invention provides alpha-carboline compounds of formula I: | 12-09-2010 |
Walter Hepperle, Offenburg DE
Patent application number | Description | Published |
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20140182993 | CENTRIFUGAL PENDULUM AND CLUTCH DISC HAVING THE LATTER - A centrifugal pendulum and a clutch disk with a pendulum flange provided thereon, rotational about an axis of rotation, and several pendulum weights distributed over the circumference and received on the pendulum flange in a pivotal fashion. In order to at least reduce noise development due to mass momentum of inertia acting here caused by the centrifugal pendulum, the pendulum flange is received on a rotational part, rotating on an axis of rotation, and a friction clutch is effectively arranged between the pendulum flange and said part. | 07-03-2014 |
20140298952 | DRIVE TRAIN - A drive train including an internal combustion engine having a predefined number of cylinders, and operable in a first engine operating state in which all cylinders are in operation, and a second operating state in which some of the cylinders are not in operation. The drive train has a torsional-vibration damping system with at least one torsional-vibration damper and at least one centrifugal-force pendulum. In order to improve the torsional-vibration behavior of the drive train, a centrifugal-force pendulum and optionally a torsional-vibration damper are adapted to control torsional-vibration behavior of the engine in one operating state, and a torsional-vibration damper and optionally a second centrifugal-force pendulum are adapted to control the torsional-vibration behavior of the engine in the other engine operating state. | 10-09-2014 |