Patent application number | Description | Published |
20090298855 | Protein Tyrosine Kinase Inhibitors - The present invention relates to compounds of the Formula I, the pharmaceutically acceptable salts and stereoisomers thereof, which inhibit, regulate and/or modulate tyrosine kinase signal transduction, compositions which contain these compounds, and methods of using them to treat tyrosine kinase-dependent diseases and conditions in mammals: | 12-03-2009 |
20100015140 | Inhibitor Compounds and Cancer Treatment Methods - A synergistically effective combination of an anti-cancer agent and a therapeutic compound, such as an mTOR-Rictor complex inhibitor, a Serine 473 phosphorylation inhibitor, an AKT2 inhibitor, or a combination thereof, for use in the treatment of cancer, and methods and uses thereof. Also included are methods and uses of a thiosemicarbazone for treating a cancer in a mammal in need thereof characterized by over-expression of RAS, by an EGFR mutation, and/or by over-expression of AKT2. | 01-21-2010 |
20110152281 | COMPOUNDS AND METHOD FOR TREATMENT OF CANCER - The invention relates to a compound of Formula (I) and/or a pharmaceutically-acceptable salt, hydrate, solvate, tautomer, optical isomer, E-isomer, Z-isomer, or combination thereof, wherein X is selected from S or O; R | 06-23-2011 |
20110281887 | COMPOUNDS AND METHOD FOR TREATMENT OF CANCER - The present invention is directed to methods of use of a compound of Formula I: | 11-17-2011 |
20120077820 | COMPOUNDS AND METHOD FOR TREATMENT OF CANCER - The present invention is directed to methods of use of a compound of Formula I: | 03-29-2012 |
20120195887 | Inhibitor Compounds and Cancer Treatment Methods - A synergistically effective combination of an anti-cancer agent and a therapeutic compound, such as an mTOR-Rictor complex inhibitor, a Serine 473 phosphorylation inhibitor, an AKT2 inhibitor, or a combination thereof, for use in the treatment of cancer, and methods and uses thereof. Also included are methods and uses of a thiosemicarbazone for treating a cancer in a mammal in need thereof characterized by over-expression of RAS, by an EGFR mutation, and/or by over-expression of AKT2. | 08-02-2012 |
20130165449 | Compounds and Method for Treatment of Cancer - The present invention is directed to methods of use of a compound of Formula I: | 06-27-2013 |
20130231345 | Compounds and Method for Treatment of Cancer - The invention relates to a compound of Formula I: | 09-05-2013 |
20140072555 | Inhibitor Compounds and Cancer Treatment Methods - A synergistically effective combination of an anti-cancer agent and a therapeutic compound, such as an mTOR-Rictor complex inhibitor, a Serine 473 phosphorylation inhibitor, an AKT2 inhibitor, or a combination thereof, for use in the treatment of cancer, and methods and uses thereof. Also included are methods and uses of a thiosemicarbazone for treating a cancer in a mammal in need thereof characterized by over-expression of RAS, by an EGFR mutation, and/or by over-expression of AKT2. | 03-13-2014 |
20150019190 | PROGRAMMABLE CELL MODEL FOR DETERMINING CANCER TREATMENTS - The disclosure relates to a programmable cancer cell model that may be customized to simulate the effect of gene mutations, for example mutations identified from a particular cancer patient's tissue sample. The simulation may be used to assess the likelihood of a candidate treatment resulting in stable remission for the patient. The model makes use of a fuzzy cognitive map (FCM) simulator that employs a matrix to represent healthy cell signaling relationships and an input disease vector representing one or more genetic mutations. The disease state vector is multiplied by the matrix to produce a stable diseased cell state vector after multiple iterations. A candidate treatment may then be proposed, based upon the diseased cell state vector. After multiple iterations with a treatment vector, the efficacy of the proposed treatment on the patient's particular cancer can be assessed, reducing reliance on the traditional trial and error approach. | 01-15-2015 |
Patent application number | Description | Published |
20100086559 | POLYPEPTIDE FORMULATION - The present invention relates to an aqueous pharmaceutical composition suitable for long-term storage of polypeptides containing an Fc domain of an immunoglobulin, methods of manufacture, methods of administration and kits containing same. | 04-08-2010 |
20120148587 | POLYPEPTIDE FORMULATION - The present invention relates to an aqueous pharmaceutical composition suitable for long-term storage of polypeptides containing an Fc domain of an immunoglobulin, methods of manufacture, methods of administration and kits containing same. | 06-14-2012 |
20120225017 | MIXED MICELLES - This disclosure is directed to mixed micelle compositions for administration of e.g., therapeutic agents or imaging agents to a subject. | 09-06-2012 |
20120282263 | COMPOSITIONS FOR INHIBITING MASP-2 DEPENDENT COMPLEMENT ACTIVATION - The present invention relates to anti-MASP-2 inhibitory antibodies and compositions comprising such antibodies for use in inhibiting the adverse effects of MASP-2 dependent complement activation. | 11-08-2012 |
20130035362 | Stable Anti-inflammatory Solutions for Injection - The present invention relates to stable liquid formulations of ketoprofen, amitriptyline, and oxymetazoline. | 02-07-2013 |
20150031728 | Cyclooxygenase Inhibitor and Calcium Channel Antagonist Compositions and Methods for Use in Urological Procedures - Compositions of a cyclooxygenase inhibitor and a calcium channel antagonist in a liquid carrier. The composition may be administered the urinary tract during urological diagnostic, interventional, surgical and other medical procedures. One disclosed composition comprises ketoprofen and nifedipine in a liquid irrigation carrier, and includes a solubilizing agent, stabilizing agents and a buffering agent. | 01-29-2015 |
20160002349 | COMPOSITIONS FOR INHIBITING MASP-2 DEPENDENT COMPLEMENT ACTIVATION - The present invention relates to anti-MASP-2 inhibitory antibodies and compositions comprising such antibodies for use in inhibiting the adverse effects of MASP-2 dependent complement activation. | 01-07-2016 |
Patent application number | Description | Published |
20120084644 | CONTENT PREVIEW - Methods, systems and machine readable tangible storage media that can provide one or more previews of content of a file or other object are described. In one embodiment, a preview of content of external data that is referenced by a link within a document is presented while the document is presented (e.g. displayed) by a first application, and the preview can be displayed in a bubble that is adjacent to and points to the link; the content of the external data is not accessible to the first application in one embodiment and the preview is presented by a non-native application or service which cannot create or edit the content of the external data. Other embodiments are also described. | 04-05-2012 |
20120185498 | Tokenized Search Suggestions - Embodiments of tokenized search suggestions include generating, by at least one suggestion engine executing on a data processing system, first suggestions based on first text input in a text input field. The first suggestions are displayed on a display device and a selection of one of the first suggestions is received. The first text input is replaced with a first token corresponding to the selected one of the first suggestions. The at least one suggestion engine generates second suggestions based on second text input in the text input field and filters the second suggestions using the selected one of the first suggestions. The filtered selections are displayed on a display device. | 07-19-2012 |
20120203766 | FACETED SEARCH RESULTS - A data processing system receives a first user input comprising a search query. The data processing system displays in a search interface accessible across a plurality of computer application programs, a plurality of results matching the search query. The results are categorized into a plurality of categories and only a first subset of all results are displayed for each of the plurality of categories. The data processing system receives a second user input comprising a selection of one of the plurality of categories. In response to the second user input, the data processing system displays, in the search interface, a second subset of results, wherein the second subset is categorized into one or more subcategories of the selected category. | 08-09-2012 |
20130290291 | Tokenized Search Suggestions - Embodiments of tokenized search suggestions include generating, by at least one suggestion engine executing on a data processing system, first suggestions based on first text input in a text input field. The first suggestions are displayed on a display device and a selection of one of the first suggestions is received. The first text input is replaced with a first token corresponding to the selected one of the first suggestions. The at least one suggestion engine generates second suggestions based on second text input in the text input field and filters the second suggestions using the selected one of the first suggestions. The filtered selections are displayed on a display device. | 10-31-2013 |
20140358902 | FACETED SEARCH RESULTS - A data processing system receives a first user input comprising a search query. The data processing system displays in a search interface accessible across a plurality of computer application programs, a plurality of results matching the search query. The results are categorized into a plurality of categories and only a first subset of all results are displayed for each of the plurality of categories. The data processing system receives a second user input comprising a selection of one of the plurality of categories. In response to the second user input, the data processing system displays, in the search interface, a second subset of results, wherein the second subset is categorized into one or more subcategories of the selected category. | 12-04-2014 |
20150199371 | TOKENIZED SEARCH SUGGESTIONS - Embodiments of tokenized search suggestions include generating, by at least one suggestion engine executing on a data processing system, first suggestions based on first text input in a text input flea The first suggestions are displayed on a display device and a selection of one of the first suggestions is received. The first text input is replaced with a first token corresponding to the selected one of the first suggestions. The at least one suggestion engine generates second suggestions based on second text input in the text input field and filters the second suggestions using the selected one of the first suggestions. The filtered selections are displayed on a display device. | 07-16-2015 |
Patent application number | Description | Published |
20120038492 | System and Method to Assess and Report the Health of a Tire - The different advantageous embodiments provide an apparatus comprising a number of tires for a vehicle, a number of systems, and a number of processor units. The number of systems is configured to generate data about the number of tires and the vehicle. The number of processor units is configured to monitor the data and manage the health of the number of tires. | 02-16-2012 |
20120041639 | System and Method to Assess and Report the Health of Landing Gear Related Components - The different advantageous embodiments provide an apparatus comprising a number of landing gear components for a vehicle, a number of systems, and a number of processor units. The number of systems is configured to generate data about the number of landing gear components and the vehicle. The number of processor units is configured to monitor the data and manage health of the number of landing gear components. | 02-16-2012 |
20130127642 | Runway Condition Monitoring - A method and apparatus are present for monitoring a runway. Data is received about the runway from a number of sensors associated with an aircraft while the aircraft performs an operation on the runway. A number of conditions are identified for the runway using the data received from the number of sensors. | 05-23-2013 |
20140222325 | SYSTEM AND METHOD TO ASSESS AND REPORT THE HEALTH OF LANDING GEAR RELATED COMPONENTS - The different advantageous embodiments provide an apparatus comprising a number of landing gear components for a vehicle, a number of systems, and a number of processor units. The number of systems is configured to generate data about the number of landing gear components and the vehicle. The number of processor units is configured to monitor the data and manage health of the number of landing gear components. | 08-07-2014 |
Patent application number | Description | Published |
20090307476 | SYSTEM AND METHOD OF DELAYING POWER-UP OF AN INFORMATION HANDLING SYSTEM - A system and method of delaying power-up of an information handling system is disclosed. According to an aspect, a method of powering an information handling system can include detecting a delay power-up setting within a basic input output system (BIOS) of a particular information handling system using a management controller. The management controller can be configured to delay power-up of the particular information handling system. The method can further include enabling a power-up of the particular information handling system in response to the delay power-up setting using the management controller. | 12-10-2009 |
20100118734 | HOST DISCOVERY ACROSS DIFFERENT ADDRESS SPACES - The “dual stack” capability of a network supporting two or more address spaces is used to perform host discovery in the network address space of one network address format using the network address space of another network format (e.g., via a PING sweep in the network address space of the other network format). The host discovery can be performed using addressing in a smaller network address space (e.g., IPv4 network address format) to discover hosts in a larger network address space (e.g., IPv6 network address format), or vice versa. | 05-13-2010 |
20120158890 | NATIVE BI-DIRECTIONAL COMMUNICATION FOR HARDWARE MANAGEMENT - A communication system includes a storage operable to host an operating system and a management controller configured to directly communicate with the operating system. The management controller directly communicates with the operating system through a communication channel free of an intermediate agent. The management controller is operable to asynchronously send management information to the operating system over the communication channel. The management controller is also operable to asynchronously receive management information from the operating system over the communication channel. | 06-21-2012 |
20120173862 | System and Method of Delaying Power-Up of an Information Handling System - A system and method of delaying power-up of an information handling system is disclosed. According to an aspect, a method of powering an information handling system can include detecting a delay power-up setting within a basic input output system (BIOS) of a particular information handling system using a management controller. The management controller can be configured to delay power-up of the particular information handling system. The method can further include enabling a power-up of the particular information handling system in response to the delay power-up setting using the management controller. | 07-05-2012 |
20120192007 | System and Method for Extending System Uptime while Running on Backup Power through Power Capping - A server chassis includes an uninterruptible power supply, and a server including a controller. The uninterruptible power supply is configured to provide a reserve power when a primary power is lost, and to send a power loss signal when the primary power is lost. The controller is configured to receive a desired server uptime, to receive an indication that a power limit for the server is fixed or decreasing over the desired server, to receive the power loss signal from the uninterruptible power supply, to send a power capacity query to the uninterruptible power supply, to receive a reserve power capacity of the uninterruptible power supply in response to the power capacity query, to calculate the power limit for the server based on the reserve power capacity of the uninterruptible power supply and on the desired server uptime, and to enforce the power limit on the server. | 07-26-2012 |
20140101474 | System and Method for Extending System Uptime while Running on Backup Power - A server chassis includes an uninterruptible power supply, and a server including a controller. The uninterruptible power supply is configured to provide a reserve power when a primary power is lost, and to send a power loss signal when the primary power is lost. The controller is configured to receive a desired server uptime, to receive an indication that a power limit for the server is fixed or decreasing over the desired server, to receive the power loss signal from the uninterruptible power supply, to send a power capacity query to the uninterruptible power supply, to receive a reserve power capacity of the uninterruptible power supply in response to the power capacity query, to calculate the power limit for the server based on the reserve power capacity of the uninterruptible power supply and on the desired server uptime, and to enforce the power limit on the server. | 04-10-2014 |
Patent application number | Description | Published |
20140217781 | WHEEL HOUSE LINER WITH HEMMED EDGE, AND SYSTEM AND METHOD OF MANUFACTURING THEREOF - A wheel house liner for a wheel house of a vehicle includes a main body and at least one flange along at least a portion of an end of the main body, the at least one flange forming a hemmed edge. The wheel house liner also includes a bonding agent to hold the at least one flange and the main body together, and at least one fastener hole. The main body is formed by a forming machine. The at least one flange is then formed by bending, by a bending tool, at least a portion of an end of the main body. The bonding agent may be applied to the portion of the end before or after the forming of the at least one flange. Finally, the hemmed edge is formed by folding, by the bending tool, the at least one flange against the main body. | 08-07-2014 |
20150041074 | GRILLE WINTER COVER INTERIOR TRIM ATTACHMENT - A number of variations may include a grille cover which may attach to a grille. | 02-12-2015 |
20150061277 | LINER AND METHOD OF MANUFACTURING THE SAME - A method of manufacturing a liner, such as a wheelhouse liner, includes the following steps: (a) providing a textile blank; (b) dispensing a liquid-impermeable polymer only on a portion of the textile blank; (c) bonding the liquid-impermeable material to the textile blank; (d) changing a shape of the textile blank to form the liner; and (e) trimming the liner. The liner includes a substrate wholly or partly made of a textile. The substrate has a first surface and a second surface opposite the first surface. The liner further includes a liquid-impermeable coat bonded to the substrate. The liquid-impermeable coat partially covers the first surface of the substrate in order to minimize liquid flow through the substrate. | 03-05-2015 |
20150314535 | A LINER AND METHOD OF MANUFACTURING THE SAME - A method of manufacturing a liner, such as a wheelhouse liner, includes the following steps: (a) providing a textile blank; (b) dispensing a liquid-impermeable polymer only on a portion of the textile blank; (c) bonding the liquid-impermeable material to the textile blank; (d) changing a shape of the textile blank to form the liner; and (e) trimming the liner. The liner includes a substrate wholly or partly made of a textile. The substrate has a first surface and a second surface opposite the first surface. The liner further includes a liquid-impermeable coat bonded to the substrate. The liquid-impermeable coat partially covers the first surface of the substrate in order to minimize liquid flow through the substrate. | 11-05-2015 |