Patent application number | Description | Published |
20090156659 | SYSTEM AND METHOD FOR COLLECTING, STORING, PROCESSING, TRANSMITTING AND PRESENTING VERY LOW AMPLITUDE SIGNALS - A method and apparatus for producing an effect of a chemical or biochemical agent on a system responsive to such agent, are disclosed. In practicing the method, a plurality of low-frequency time-domain signals of the agent are generated, each at a different at a different noise level within a selected noise level range. The signals are analyzed by producing spectral plots of the time-domain signals, and identifying an optimized agent-specific time-domain signal based on information in the spectral plots. A chemical or biological system responsive to the agent is exposed to the optimized time-domain signal by placing the system within the magnetic field of an electromagnetic transducer, and applying the signal to the transducer at a signal amplitude and for a period sufficient to produce in the system an agent-specific effect on the system. | 06-18-2009 |
20130041201 | System and Method for Collecting, Storing, Processing, Transmitting and Presenting Very Low Amplitude Signals - A method and apparatus for producing an effect of a chemical or biochemical agent on a system responsive to such agent, are disclosed. In practicing the method, a plurality of low-frequency time-domain signals of the agent are generated, each at a different at a different noise level within a selected noise level range. The signals are analyzed by producing spectral plots of the time-domain signals, and identifying an optimized agent-specific time-domain signal based on information in the spectral plots. A chemical or biological system responsive to the agent is exposed to the optimized time-domain signal by placing the system within the magnetic field of an electromagnetic transducer, and applying the signal to the transducer at a signal amplitude and for a period sufficient to produce in the system an agent-specific effect on the system. | 02-14-2013 |
Patent application number | Description | Published |
20090156659 | SYSTEM AND METHOD FOR COLLECTING, STORING, PROCESSING, TRANSMITTING AND PRESENTING VERY LOW AMPLITUDE SIGNALS - A method and apparatus for producing an effect of a chemical or biochemical agent on a system responsive to such agent, are disclosed. In practicing the method, a plurality of low-frequency time-domain signals of the agent are generated, each at a different at a different noise level within a selected noise level range. The signals are analyzed by producing spectral plots of the time-domain signals, and identifying an optimized agent-specific time-domain signal based on information in the spectral plots. A chemical or biological system responsive to the agent is exposed to the optimized time-domain signal by placing the system within the magnetic field of an electromagnetic transducer, and applying the signal to the transducer at a signal amplitude and for a period sufficient to produce in the system an agent-specific effect on the system. | 06-18-2009 |
20100244818 | APPARATUS AND METHOD FOR TRANSDUCING AN IN VITRO OR MAMMALIAN SYSTEM WITH A LOW-FREQUENCY SIGNAL - Method and apparatus for generating and selecting low-frequency time-domain signals capable of transducing a mammalian system, to produce an agent-specific effect on the system, are disclosed. Low-frequency time-domain signals are generated in the presence of an injected magnetic stimulus, and the resulting signals are selected by a scoring algorithm, and optionally, by testing each signal identified by the scoring algorithm for its ability to produce an agent-specific response in a in vitro system containing components that are responsive to the agent. The selected signals are used to transduce the mammalian system by applying the signals to an electromagnetic transduction coil that holds the sample. | 09-30-2010 |
20110195111 | AQUEOUS COMPOSITIONS AND METHODS - A method of forming an aqueous composition effective to produce an agent-specific effect on an agent-responsive chemical or biological system, when the composition is added to the system, is disclosed. The composition is formed by exposing an aqueous medium to a low-frequency, time-domain signal derived from the agent, until the aqueous medium acquires a detectable agent activity. Exemplary compositions are formed by exposure to a paclitaxel signal or a signal derived from a therapeutic oligonucleotide, such as GAPDH antisense RNA and PCSK9 antisense RNA. Also disclosed are methods for confirming the activity of the composition, and for preparing and testing the activity of the compositions. | 08-11-2011 |
20130041201 | System and Method for Collecting, Storing, Processing, Transmitting and Presenting Very Low Amplitude Signals - A method and apparatus for producing an effect of a chemical or biochemical agent on a system responsive to such agent, are disclosed. In practicing the method, a plurality of low-frequency time-domain signals of the agent are generated, each at a different at a different noise level within a selected noise level range. The signals are analyzed by producing spectral plots of the time-domain signals, and identifying an optimized agent-specific time-domain signal based on information in the spectral plots. A chemical or biological system responsive to the agent is exposed to the optimized time-domain signal by placing the system within the magnetic field of an electromagnetic transducer, and applying the signal to the transducer at a signal amplitude and for a period sufficient to produce in the system an agent-specific effect on the system. | 02-14-2013 |
Patent application number | Description | Published |
20090257306 | BONE CEMENT MIXING AND DELIVERY SYSTEM WITH AUTOMATED BONE CEMENT TRANSFER BETWEEN MIXER AND DELIVERY DEVICE AND METHOD OF MIXING AND AUTOMATED TRANSFER OF BONE CEMENT BETWEEN MIXER AND DELIVERY DEVICE AND METHOD OF MIXING AND AUTOMATED TRANSFER OF BONE CEMENT BETWEEN MIXER AND DELIVERY DEVICE - A bone cement mixing and delivery system is provided in which separate components of bone cement are mixed together in a mixer to form a bone cement mixture. The mixer includes a mixing paddle and a mixing shaft connected to the mixing paddle. A motor operatively engages the mixing shaft to rotate the mixing shaft and the mixing paddle to mix the components in a mixing chamber. The motor also operatively engages a transfer mechanism. After a predetermined mixing period has elapsed, the motor automatically actuates the transfer mechanism to transfer the mixture to a delivery device. The mixture is then delivered to a target site, such as a vertebral body of a patient or other anatomical site. | 10-15-2009 |
20100110820 | MOTORIZED BONE CEMENT MIXING AND DELIVERY SYSTEM THAT AUTOMATICALLY TRANSFERS BONE CEMENT BETWEEN THE MIXER AND THE DELIVERY DEVICE AND THAT AUTOMATICALLY TERMINATES THE MIXING AND DELIVERY PROCESSES - A bone cement mixing and delivery system is provided in which separate components of bone cement are mixed together in a mixer to form a bone cement mixture. The mixer includes a paddle for mixing the components in a mixing chamber and a piston that pushes the mixing cement into an attached delivery device. The system further includes a switch that disconnects the drive assembly that actuates the paddle and piston from its power source. The switch is automatically tripped by a follower that moves upon actuation of the drive assembly. Once the cement is mixed and transferred to the delivery device, the follower trips the switch to automatically deactivate the drive assembly. | 05-06-2010 |
20110194371 | MOTORIZED BONE CEMENT MIXING AND DELIVERY SYSTEM THAT ALLOWS A USER TO DETACH THE DELIVERY DEVICE FROM THE MIXER FOR DELIVERY - A bone cement mixing and delivery system including a mixer and a delivery device. The mixer includes a paddle for mixing the components and a piston that pushes the mixed cement into the attached delivery device. The delivery device includes a tube into which the bone cement is forced from the mixer, and a plunger that forces the cement out of the tube during the medical procedure. The tube includes an entry port through which cement is introduced into the tube from the mixer. A one-way valve attached to the tube allows the cement to flow from the mixer through the entry port. After the cement is loaded in the tube, the delivery device is removed from the mixer. The valve blocks flow out of the entry port when the plunger is depressed. | 08-11-2011 |
20120218851 | MOTORIZED BONE CEMENT MIXING AND DELIVERY SYSTEM WITH A FLEXIBLE DELIVERY EXTENSION TUBE AND ENLARGED CONNECTOR FOR DELIVERING CEMENT INTO LIVING TISSUE - A bone cement mixing and delivery system including a mixer, a delivery device, and a flexible extension tube. A connector is attached to a distal end of the flexible tube. The connector includes a housing, a spindle configured with a fitting, and an enlarged knob. The spindle is seated within the housing and is configured to rotate between a closed and open position. In the open position, the spindle allows flow from the delivery device flexible extension tube into a bore of the spindle and into the spindle fitting. A delivery cement cannula is attached to the spindle fitting for allowing cement to travel from the delivery tube into living tissue. The enlarged knob is used to rotate the spindle from an open to a closed state and vice versa. | 08-30-2012 |
Patent application number | Description | Published |
20080255563 | INSTRUMENTATION AND METHOD FOR PROVIDING SURGICAL ACCESS TO A SPINE - A system for accessing a spine from a curved postero-lateral approach may include a curved cannula positioned along a curved path from an opening in the skin to a location proximate the spine. A targeting post may be inserted adjacent the spine to determine the location. A peritoneal retractor and a guide member may be first inserted to establish the path between the tissues and fascia, and one or more intermediate cannulas may be temporarily inserted over the guide member to dilate the tissues prior to insertion of the main cannula. An interbody device may be implanted in an intervertebral space through the cannula. An endoscope may be inserted through the targeting post or the cannula. The system may include instruments with shafts which are flexible or are curved to match the curve of the curved cannula, including a rongeur, curette, rasp, distractor, trial implant, probe, tamp, and implant inserter. | 10-16-2008 |
20090012356 | ENDOSCOPIC DELIVERY DEVICES AND METHODS - Disclosed herein are various devices and methods that can be utilized independently or in conjunction with each other for endoscopic delivery of a wide ranges of medical devices, such as, for example, an endoscopic gastrointestinal bypass sleeve with an attachment cuff. Components of the system can include a space-creating device; an expandable fastener system with flower petal-shaped retention elements; and an endoscopic curved needle driver system. | 01-08-2009 |
20120209164 | Methods of replacing a gastrointestinal bypass sleeve for therapy adjustment - Methods are disclosed for replaceable attachment of an endoluminal gastrointestinal device, such as an artificial stoma device, a gastrointestinal bypass sleeve device or an attachment cuff, within a patient's digestive tract for treatment of obesity. | 08-16-2012 |
20120232459 | DEVICES AND METHODS FOR ENDOLUMENAL GASTROINTESTINAL BYPASS - The present invention provides devices and methods for attachment of an endolumenal gastrointestinal device, such as an artificial stoma device, a gastrointestinal bypass sleeve or other therapeutic or diagnostic device, within a patient's digestive tract. In one application of the invention, an endolumenal bypass sleeve is removably attached in the vicinity of the gastroesophageal junction to treat obesity and/or its comorbidities, such as diabetes. The bypass sleeve may be at least partially deployed by eversion. | 09-13-2012 |
20150238340 | METHODS OF REPLACING A GASTROINTESTINAL BYPASS SLEEVE FOR THERAPY ADJUSTMENT - Methods are disclosed for replaceable attachment of an endoluminal gastrointestinal device, such as an artificial stoma device, a gastrointestinal bypass sleeve device or an attachment cuff, within a patient's digestive tract for treatment of obesity. | 08-27-2015 |