Patent application number | Description | Published |
20160069201 | Attachment Faces for Clamped Turbine Stator of a Gas Turbine Engine - An airfoil fairing shell for a gas turbine engine includes an airfoil section between an outer vane endwall and an inner vane endwall, at least one of the outer vane endwall and the inner vane endwall including a radial attachment face, a suction side tangential attachment face, a pressure side tangential attachment face, and an axial attachment face. | 03-10-2016 |
20160076383 | FILM COOLED ARTICLE - A film cooled component includes multiple film cooling holes. At least one of the film cooling holes has an elliptical cross sectional opening along the exterior surface of the film cooled component. | 03-17-2016 |
20160084096 | CLAMPED VANE ARC SEGMENT HAVING LOAD-TRANSMITTING FEATURES - A vane arc segment includes a radially inner and outer platforms and an airfoil mechanically clamped between the platforms. The airfoil has an airfoil section that extends radially between radially inner and outer fairing platforms. At least one of the fairing platforms includes forward and aft sides, circumferential sides, and a gas path side and an opposed radial side. The radial side includes a plurality of protrusions that have faces that are oriented substantially normal to, respectively, radial, tangential, and axial load transmission directions of the airfoil such that the faces, respectively, primarily bear radial, tangential, and axial load transmissions of the airfoil. | 03-24-2016 |
20160090851 | AIRFOIL ASSEMBLY WITH SPACER AND TIE-SPAR - An airfoil assembly includes at least one airfoil that has a hollow interior. First and second platforms are disposed between the airfoil. At least one tie-spar extends along an axis through the first platform, the hollow interior of the airfoil, and the second platform. There is a thermal expansion difference between a thermal expansion of the tie-spar in the axial direction and the combined thermal expansion of the airfoil and the first and second platform in the axial direction. At least one spacer portion is arranged on the tie-spar. The spacer portion has a thermal expansion in the axial direction that is greater than the thermal expansion difference such that the spacer portion maintains the tie-spar under tension and clamps the first and second platforms on the airfoil. | 03-31-2016 |
Patent application number | Description | Published |
20080214465 | Method of administering and using VEGF inhibitors for the treatment of human cancer - A method of treating a human patient suffering from cancer, comprising administering an effective amount of a vascular endothelial growth factor (VEGF) trap antagonist to the human patient, the method comprising: (a) administering to the patient an initial dose of at least approximately 0.3 mg/kg of the VEGF antagonist; and (b) administering to the patient a plurality of subsequent doses of the VEGF antagonist in an amount that is approximately the same or less of the initial dose, wherein the subsequent doses are separated in time from each other by at least one day. The methods of the invention are useful for treating a human cancer selected from the group consisting of renal cell carcinoma, pancreatic carcinoma, breast cancer, prostate cancer, colorectal cancer, malignant mesothelioma, multiple myeloma, ovarian cancer, and melanoma. The invention is further useful for treating a condition which benefits from the reduction of VEGFA and placental growth factor (PLGF). | 09-04-2008 |
20080214466 | Method of administering and using VEGF inhibitors for the treatment of human cancer - A method of treating a human patient suffering from cancer, comprising administering an effective amount of a vascular endothelial growth factor (VEGF) trap antagonist to the human patient, the method comprising: (a) administering to the patient an initial dose of at least approximately 0.3 mg/kg of the VEGF antagonist; and (b) administering to the patient a plurality of subsequent doses of the VEGF antagonist in an amount that is approximately the same or less of the initial dose, wherein the subsequent doses are separated in time from each other by at least one day. The methods of the invention are useful for treating a human cancer selected from the group consisting of renal cell carcinoma, pancreatic carcinoma, breast cancer, prostate cancer, colorectal cancer, malignant mesothelioma, multiple myeloma, ovarian cancer, and melanoma. The invention is further useful for treating a condition which benefits from the reduction of VEGFA and placental growth factor (PLGF). | 09-04-2008 |
20090285841 | ANTITUMOR COMBINATIONS CONTAINING A VEGF-INHIBITING AGENT AND 5FU OR A DERIVATIVE THEREOF - This invention relates to antitumor combinations comprising a VEGF inhibitor combined with 5-fluorouracil or with a 5-fluoropyrimidine derivative that are therapeutically useful in the treatment of neoplastic diseases, and pharmaceutical compositions comprising such combinations. | 11-19-2009 |
20130184205 | ANTITUMOR COMBINATIONS CONTAINING A VEGF-INHIBITING AGENT AND 5FU OR A DERIVATIVE THEREOF - This invention relates to antitumor combinations comprising a VEGF inhibitor combined with 5-fluorouracil or with a 5-fluoropyrimidine derivative that are therapeutically useful in the treatment of neoplastic diseases, and pharmaceutical compositions comprising such combinations. | 07-18-2013 |
Patent application number | Description | Published |
20130216933 | PROTECTIVE EDGE SEAL FOR MEMBRANE ION EXCHANGE - A unitized electrode assembly ( | 08-22-2013 |
20140356757 | FUEL CELL ELECTRODE WITH GRADIENT CATALYST STRUCTURE - An example of a stable electrode structure is to use a gradient electrode that employs large platinum particle catalyst in the close proximity to the membrane supported on conventional carbon and small platinum particles in the section of the electrode closer to a GDL supported on a stabilized carbon. Some electrode parameters that contribute to electrode performance stability and reduced change in ECA are platinum-to-carbon ratio, size of platinum particles in various parts of the electrode, use of other stable catalysts instead of large particle size platinum (alloy, etc), depth of each gradient sublayer. Another example of a stable electrode structure is to use a mixture of platinum particle sizes on a carbon support, such as using platinum particles that may be 6 nanometers and 3 nanometers. A conductive support is typically one or more of the carbon blacks. | 12-04-2014 |
20150266028 | FUEL CELL MEMBRANE ELECTRODE ASSEMBLY FABRICATION PROCESS - An exemplary method of processing a catalyst ink includes ultrasonicating the catalyst ink. The exemplary method includes high shear mixing the catalyst ink. | 09-24-2015 |
20150318559 | FUEL CELL CATALYST TREATMENT - According to an embodiment, a method of preparing a catalyst for a fuel cell component includes soaking catalyst particles in citric acid. The catalyst particles are then rinsed after having been soaked in the citric acid. Catalyst particles are dried after they have been rinsed. When desired, the pre-treated catalyst particles may be incorporated into a catalyst ink used for making a fuel cell component. | 11-05-2015 |