Laura J.
Laura J. Bierut, St. Louis, MO US
Patent application number | Description | Published |
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20090176878 | GENETIC POLYMORPHISMS AND SUBSTANCE DEPENDENCE - The invention encompasses a method for identifying subjects at risk for substance dependence by detecting the presence of polymorphism in the CHRNA5-CHRNA3-CHRNB4 gene cluster and the CHRNA4 gene. The invention also encompasses determining the response of a subject to a therapeutic substance, treating substance dependence in a subject, and evaluating the response of a subject to a substance cessation treatment. | 07-09-2009 |
20110143344 | GENETIC POLYMORPHISMS AND SUBSTANCE DEPENDENCE - The invention encompasses methods for identifying subjects at risk for substance dependence by detecting the presence of polymorphism in the CHRNA5-CHRNA3-CHRNB4 gene cluster and the CHRNA4 gene. The invention also encompasses determining the response of a subject to a therapeutic substance, treating substance dependence in a subject, and evaluating the response of a subject to a substance cessation treatment. | 06-16-2011 |
Laura J. Brattain, Lexington, MA US
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20120117170 | SYSTEM AND METHOD FOR PROVIDING A GEO-REFERENCED VIRTUAL COLLABORATIVE ENVIRONMENT - A system for providing an image-referenced virtual collaborative environment contains a server in communication with at least a first client device and a second client device, wherein the server comprises a memory and a processor. The processor is configured by the memory to perform the steps of: extracting properties of a vector object, where the vector object is the result of a modification to a first background image performed by a first user on the first client device; placing the extracted properties of the vector object into a feature message; sending the feature message onto a specific topic on a message bus; delivering the feature message to a second user using the second client device; extracting data from the feature message; and rendering, in real time, the vector object on a second background image viewed by the second user via the second client device. | 05-10-2012 |
Laura J. Dietsche, Midland, MI US
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20080298170 | STIRRER AND APPARATUS FOR SMALL VOLUME MIXING - This invention is a stirrer, impeller or stirrer paddle used for mixing small volumes of liquid in a vessel having a small capacity for liquid, said impeller being characterized by an impeller blade connected to the bottom portion of a support, where the blade has an opening extending through the blade from the front to the back surface of the blade said opening extending across the rotational axis of the impeller. The invention is also an apparatus comprising that blade, a method of mixing components using the apparatus and an array of two or more of the apparatuses. | 12-04-2008 |
20130022751 | DISPENSING DEVICE FOR BOTH FROTH AND NON-FROTH COATINGS - A dispensing device ( | 01-24-2013 |
Laura J. Dietsche, Ii, Midland, MI US
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20150284481 | Recycle Gas Cooler Systems for Gas-Phase Polymerization Processes - Disclosed herein are improvements in recycle gas cooler systems in gas-phase polymerization processes that reduce the tendency for cooler fouling, including a recycle gas cooler system comprising a shell-and-tube heat exchanger. One or more of the tubes of the shell-and-tube heat exchanger may have a flared tube inlet at the tube sheet. The shell-and-tube heat exchanger may also be coupled to a straight inlet pipe having a length that is either at least about 5 times the inner diameter of the straight inlet pipe or at least about 15 feet, whichever is greater. | 10-08-2015 |
Laura J. Dunn, San Diego, CA US
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20150118658 | ADAPTIVE INTERFACE FOR CONTINUOUS MONITORING DEVICES - Systems and methods that continuously adapt aspects of a continuous monitoring device based on collected information to provide an individually tailored configuration are described. The adaptations may include adapting the user interface, the alerting, the motivational messages, the training, and the like. Such adaptation can allow a patient to more readily identify and understand the information provided by/via the device. | 04-30-2015 |
20150118668 | ADAPTIVE INTERFACE FOR CONTINUOUS MONITORING DEVICES - Systems and methods that continuously adapt aspects of a continuous monitoring device based on collected information to provide an individually tailored configuration are described. The adaptations may include adapting the user interface, the alerting, the motivational messages, the training, and the like. Such adaptation can allow a patient to more readily identify and understand the information provided by/via the device. | 04-30-2015 |
20150119655 | ADAPTIVE INTERFACE FOR CONTINUOUS MONITORING DEVICES - Systems and methods that continuously adapt aspects of a continuous monitoring device based on collected information to provide an individually tailored configuration are described. The adaptations may include adapting the user interface, the alerting, the motivational messages, the training, and the like. Such adaptation can allow a patient to more readily identify and understand the information provided by/via the device. | 04-30-2015 |
20150119668 | ADAPTIVE INTERFACE FOR CONTINUOUS MONITORING DEVICES - Systems and methods that continuously adapt aspects of a continuous monitoring device based on collected information to provide an individually tailored configuration are described. The adaptations may include adapting the user interface, the alerting, the motivational messages, the training, and the like. Such adaptation can allow a patient to more readily identify and understand the information provided by/via the device. | 04-30-2015 |
20150120317 | ADAPTIVE INTERFACE FOR CONTINUOUS MONITORING DEVICES - Systems and methods that continuously adapt aspects of a continuous monitoring device based on collected information to provide an individually tailored configuration are described. The adaptations may include adapting the user interface, the alerting, the motivational messages, the training, and the like. Such adaptation can allow a patient to more readily identify and understand the information provided by/via the device. | 04-30-2015 |
Laura J. Hefta, Pennington, NJ US
Patent application number | Description | Published |
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20090068192 | Fully human antibodies against human 4-1BB - Fully human antibodies and antigen-binding portions thereof that bind to human 4-1BB and that allow binding of human 4-1BB to a human 4-1BB ligand. In one aspect, the antibody is an IgG4 antibody. Also provided is a method for treating a disease in a subject comprising administering a therapeutically effective amount of the antibody to said subject. | 03-12-2009 |
20100183621 | Fully human antibodies against human 4-1BB - Fully human antibodies and antigen-binding portions thereof that bind to human 4-1BB and that allow binding of human 4-1BB to a human 4-1BB ligand. In one aspect, the antibody is an IgG4 antibody. Also provided is a method for treating a disease in a subject comprising administering a therapeutically effective amount of the antibody to said subject. | 07-22-2010 |
20120141494 | FULLY HUMAN ANTIBODIES AGAINST HUMAN 4-1BB - Fully human antibodies and antigen-binding portions thereof that bind to human 4-1BB and that allow binding of human 4-1BB to a human 4-1BB ligand. In one aspect, the antibody is an IgG4 antibody. Also provided is a method for treating a disease in a subject comprising administering a therapeutically effective amount of the antibody to said subject. | 06-07-2012 |
20140193422 | FULLY HUMAN ANTIBODIES AGAINST HUMAN 4-1BB - Fully human antibodies and antigen-binding portions thereof that bind to human 4-1BB and that allow binding of human 4-1BB to a human 4-1BB ligand. In one aspect, the antibody is an IgG4 antibody. Also provided is a method for treating a disease in a subject comprising administering a therapeutically effective amount of the antibody to said subject. | 07-10-2014 |
Laura J. Heyderman, Zofingen CH
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20100232251 | METHOD AND SYSTEM FOR CODING AND READ OUT OF INFORMATION IN A MICROSCOPIC CLUSTER COMPRISING COUPLED FUNCTIONAL ISLANDS - A method and a system for coding and reading out information in a microscopic cluster formed with coupled functional islands includes: generating the cluster by forming a regular microscopic pattern for locating the functional islands; making use of a physical or chemical property of each individual island and making use of the coupling between the functional islands; assigning different information to different energy levels of the cluster; effecting a change of the physical or chemical property of at least one functional island in order to change the energy level of the cluster to the energy level equivalent to the information content to be coded; and reading out the information. These measures allow forming a cluster having distinct energy levels, each being assigned to a distinct information content. These systems pave the way for future devices based on clusters of coupled islands and, armed with the complete knowledge of the energy states, the door is opened for use of these finite multistate clustered structures in future spintronic devices, for example for data storage, memory applications or to perform logic operations. | 09-16-2010 |
Laura J. Kramer, Danville, IN US
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20150033621 | Flower Pot Protector for Outdoor/Indoor Planters - The Flower Pot Protector provides flowerpots protection from the harsh outdoor elements. It also provides a decorative esthetics whether being used indoors or outdoors. A disc is used and inserted into the underside of the fabric/vinyl covered pot eliminating moisture from entering into the cavity of the flowerpot. By covering the flowerpot and eliminating moisture from entering into the pot, minimal expansion of moisture keeps the pot from cracking and breaking during the freezing outdoor elements. | 02-05-2015 |
Laura J. Miranti US
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20110316266 | Board book photo album - A board book album having stiff pages constructed from layers of white board material and having “hidden pockets,” each pocket holding two photographs, back-to-back, that are framed in die cutout openings in each page. Spacers to which the backs of the spreads forming the pages are glued allow each page to accommodate the thickness of the photographs without damaging the outer binding. Each photograph is protected by a piece of clear plastic. Each page can have a small concave notch along its unbound edge in order to allow a user to turn the pages more easily. The cover can have a frame attached thereto for holding a photograph. The album is sturdy enough to be handled by a small child without the photographs being damaged. | 12-29-2011 |
Laura J. Miranti, The Woodlands, TX US
Patent application number | Description | Published |
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20090284002 | Board book photo album - A board book album having stiff pages with “hidden pockets,” each pocket holding two photographs, back-to-back, that are framed in die cutout openings in each page. Spacers inside the bound and unbound edges of each page allow the page to accommodate the thickness of the photographs without damaging the binding. Each photograph is protected by a piece of clear plastic. Each page can have a small concave notch along its unbound edge in order to allow a user to turn the pages more easily. The cover can have a frame attached thereto for holding a photograph. The album is sturdy enough to be handled by a small child without the photographs being damaged. | 11-19-2009 |
Laura J. Niedernhofer, Pittsburgh, PA US
Patent application number | Description | Published |
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20090075902 | INHIBITING THE SIGNS OF AGING BY INHIBITING NF-KAPPA B ACTIVATION - The present invention relates to methods and compositions for reducing and/or delaying one or more signs of aging which comprise inhibiting NF-kappa B activation. It is based, at least in part, on the discovery that a peptide which inhibits IKK-β interaction with NEMO, linked to a transducing peptide, inhibits the development of various indicia of senescence in a murine model of aging, Ercc1 | 03-19-2009 |
20120004263 | Compounds for the treatment of pathologies associated with aging and degenerative disorders - The present invention relates to methods of inhibiting one or more signs of aging and/or degenerative disorder in a subject in need of such treatment, which comprise administering, to the subject, an effective amount of one or more of the compounds as set forth herein. “Inhibiting a sign of aging or degenerative disorder” means reducing the risk of occurrence, delaying the onset, slowing the progression, and/or reducing the severity and/or manifestation, of a sign of aging or degenerative disorder, and includes, but is not limited to, preventing the occurrence, development or progression of a sign of aging or degenerative disorder. | 01-05-2012 |
20150018346 | COMPOUNDS FOR THE TREATMENT OF PATHOLOGIES ASSOCIATED WITH AGING AND DEGENERATIVE DISORDERS - The present invention relates to methods of inhibiting one or more signs of aging and/or degenerative disorder in a subject in need of such treatment, which comprise administering, to the subject, an effective amount of one or more of the compounds as set forth herein. “Inhibiting a sign of aging or degenerative disorder” means reducing the risk of occurrence, delaying the onset, slowing the progression, and/or reducing the severity and/or manifestation, of a sign of aging or degenerative disorder, and includes, but is not limited to, preventing the occurrence, development or progression of a sign of aging or degenerative disorder. | 01-15-2015 |
Laura J. Odonnell, Hermosa Beach, CA US
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20160050212 | METHOD AND APPARATUS FOR ASSIGNING DEVICES TO A MEDIA SERVICE - A user interface is used to assign different devices and device types to media services where the number of different devices and device types that are capable of being assigned is determined by access privilege information corresponding to such media services. When a number of devices of a specific type are assigned where such a number exceeds a limit specified in the access privilege information, the assignment of additional devices of that specific type is halted. | 02-18-2016 |
Laura J. Silva, West Dublin, OH US
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20160038904 | Microchannel Apparatus and Methods of Conducting Unit Operations With Disrupted Flow - The invention described herein concerns microchannel apparatus that contains, within the same device, at least one manifold and multiple connecting microchannels that connect with the manifold. For superior heat or mass flux in the device, the volume of the connecting microchannels should exceed the volume of manifold or manifolds. Methods of conducting unit operations in microchannel devices having simultaneous disrupted and non-disrupted flow through microchannels is also described. | 02-11-2016 |
Laura J. Van 'T Veer, San Francisco, CA US
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20140364434 | Biomarkers for Prediction of Response to PARP Inhibition in Breast Cancer - Methods and systems for identifying a cancer patient suitable for treatment with a PARP inhibitor. A 6-gene, 7-gene and 8-gene predictor panels of genes that are predictive of patient resistance or sensitivity to PARP inhibitors such as Olaparib. | 12-11-2014 |
Laura J. Van'T Veer, Amsterdam NL
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20090239214 | Prognosis of breast cancer patients - The present invention relates to sets of genetic markers whose expression is correlated with prognosis of breast cancer in individuals having breast cancer. Specifically, the invention provides sets of markers whose expression patterns can be used to differentiate individuals having a good prognosis, e.g., no reoccurrence or metastasis within five years of initial diagnosis, and individuals having a poor prognosis, e.g., reoccurrence or metastasis within five years of initial diagnosis. The invention relates to methods of prognosis using these markers. The invention also relates to microarrays containing probes to these markers, and to kits containing ready-to-use microarrays and computer software for data analysis using the prognostic and statistical methods disclosed herein. | 09-24-2009 |