Macmahon
Alistair John Macmahon, Oxfordshire GB
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20090282987 | SYSTEM, POD AND METHOD FOR PREPARING A BEVERAGE - The present invention provides a system, pod and method for preparing a beverage containing extract from a water infusible ingredient and, in one preferred embodiment, provides: a system for preparing a beverage comprising: at least one compartment defining a storage volume for containing, or for receiving a pod containing, an extraction ingredient of roast and ground coffee for forming a beverage; and one or more jetting apertures arranged for jetting in use a liquid into the at least one compartment, wherein: the system operates in use at a pressure of less than 8.5×10 | 11-19-2009 |
Diarmuid Macmahon, Dublin IE
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20140265781 | PANEL WITH MAGNETIC HINGE - A panel includes a housing. The housing may have a hinge closed magnet and a hinge opened magnet. The panel may include a door magnetically hinged to the housing for positioning the door between a closed position and an open position. The door may have a door hinge magnet. The door hinge magnet is magnetically attracted to the hinge closed magnet to retain the door in the closed position. The door hinge magnet is magnetically attracted to the hinge opened magnet to retain the door in the open position. | 09-18-2014 |
Edward Brian Macmahon, Exeter, NH US
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20150257915 | METHODS AND APPARATUSES FOR THE EXTERNAL DISTRACTION IN THE ASSISTANCE OF SPINAL DEFORMITIES - Spinal distraction systems including methods of use. | 09-17-2015 |
Jeffrey P. Macmahon, San Francisco, CA US
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20130172315 | SUBSTITUTED ANILINES AS CCR(4) ANTAGONISTS - Aniline compounds are provided which bind to CCR(4) and are useful for the treatment of diseases such as allergic diseases, autoimmune diseases, graft rejection and cancer. | 07-04-2013 |
John Macmahon, Oxon GB
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20090232944 | FLEXIBLE PAD FOR PREPARING A BEVERAGE - The present invention provides a flexible pad ( | 09-17-2009 |
20090311384 | POD FOR PREPARING A BEVERAGE - A pod for preparing a beverage comprising: a rigid or semi-rigid sidewall; a rigid or semi-rigid upper surface containing one more apertures forming an inlet of the pod; a lower surface formed at least partially from filtering material, the filtering material forming an outlet of the pod; the sidewall, upper surface and lower surface together defining a storage volume extending from the inlet to the outlet and containing a water-soluble composition, or a combination or mixture of water-soluble compositions for forming a beverage; wherein the rigid or semi-rigid sidewall maintains a physical separation of the filtering material and the upper surface during use. | 12-17-2009 |
20100178391 | FLEXIBLE PAD FOR PREPARING A BEVERAGE - The present invention provides a flexible pad for preparing a beverage comprising: a filter bag defining a storage volume; the storage volume containing a water-soluble composition or a combination or mixture of water-soluble compositions for forming a beverage; wherein the storage volume further contains one or more absorbent elements. | 07-15-2010 |
John Macmahon, Brackley GB
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20080254169 | Pad For Preparing a Beverage - A pad for preparing a beverage comprising: an upper part comprising a rigid or semi-rigid upper element containing one or more apertures forming an inlet of the pad; a flexible lower element depending from the upper part and formed at least partially from filtering material, the filtering material forming an outlet of the pad; the upper part and lower element together defining a storage volume containing a water-soluble composition or a combination or mixture of water-soluble compositions for forming a beverage, wherein the upper part comprises a flexible water-impermeable layer joined to the rigid or semi-rigid upper element. | 10-16-2008 |
20080260928 | Flexible Pad for Preparing a Beverage - A flexible pad for preparing a beverage comprising: a filter bag defining a storage volume; the storage volume containing a water-soluble composition or a combination or mixture of water-soluble compositions for forming a beverage; wherein the storage volume further contains a plurality of non-soluble absorbent particles having a particle size, before use, of 25 microns to 10 mm. | 10-23-2008 |
20090004335 | Pod for Preparing a Beverage - The present invention provides a pod for preparing a beverage comprising: a lower compartment ( | 01-01-2009 |
John Macmahon, Exeter, NH US
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20150257915 | METHODS AND APPARATUSES FOR THE EXTERNAL DISTRACTION IN THE ASSISTANCE OF SPINAL DEFORMITIES - Spinal distraction systems including methods of use. | 09-17-2015 |
Patrick Macmahon, Singapore SG
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20090320712 | AMUSEMENT RIDE - A carriage assembly for mounting to a track following a curvilinear path, said assembly comprising a trolley mountable to said track through a track engagement assembly, an orientation of the trolley varying with an orientation of the track; a carriage rotationally mounted to the trolley, such that the carriage is free to rotate about two axes relative to the trolley, wherein rotation about the two axes maintains the carriage in a horizontal orientation independent of the orientation of the track. | 12-31-2009 |
Stephen Macmahon, New South Wales AU
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20110158979 | GENETIC COMPONENT OF COMPLICATIONS IN TYPE 2 DIABETES - The invention provides with means to predict, in subjects affected by type 2 diabetes (T2D), the probability of developing complications related to the disease. The invention involves 1) use of genetic features (SNPs, STRs, or other genomic markers) together with other chromosomal features and phenotypic information to establish a patient profile specifically developed for prediction of complications of T2D 2) use of a set of SNPs allowing to discriminate between individuals according to their descent. The invention also provides with methods for characterizing and selecting, within a population of subjects with type-2 diabetes, subjects that are suited for clinical trials based on the identification of one or more genetic features. Also described are combinations and kits for carrying out the above-described methods. | 06-30-2011 |
Stephen Macmahon, Sydney AU
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20100099091 | GENETIC COMPONENT OF COMPLICATIONS IN TYPE 2 DIABETES - The invention provides with means to predict, in subjects affected by type 2 diabetes (T2D), the probability of developing complications related to the disease. The invention involves 1) use of genetic features (SNPs, STRs, or other genomic markers) together with other chromosomal features and phenotypic information to establish a patient profile specifically developed for prediction of complications of T2D 2) use of a set of SNPs allowing to discriminate between individuals according to their descent. A preferred set of genomic markers selected for their association with complications of T2D is provided that can be used with a set of complementary phenotypic markers to evaluate the risk for an individual affected by T2D to develop complications related to the disease and to evaluate the likelihood that an individual affected by T2D type will benefit from treatments reducing the risk of developing such complications. | 04-22-2010 |
20100136540 | Methods and compositions for characterizing patients for clinical outcome trials - The invention provides with methods for characterizing and selecting, within a population of subjects with type-2 diabetes, subjects that are suited for clinical trials based on the identification of one or more genetic features, which are single nucleotide polymorphisms (SNPs), short tandem repeats (STRs), and/or other genomic markers. The invention further involves characterizing these subjects based on the probability of developing complications related to type-2 diabetes, such as, myocardial infarction, stroke and albuminuria. Also described are combinations and kits for carrying out the above-described methods. | 06-03-2010 |
20120134981 | GENES LINKING SEVERAL COMPLICATIONS OF TYPE-2 DIABETES (T2D) - The invention provides means and methods to predict, in subjects affected by type II diabetes (T2D), the probability of developing complications which include, but are not limited to, micro/macrovascular disorder, hypertension, neuropathy, atrial fibrillation, nephropathy and other major adverse cardiovascular events (MACE) that are associated with the disease, by detecting one or more genetic features. The genetic features that are useful in prediction include, but are not limited to, genes, single nucleotide polymorphisms (SNPs) and other genomic markers. The invention further involves characterizing individuals based on the probability of developing complications related to T2D, such as, micro/macrovascular disorder, hypertension, neuropathy, atrial fibrillation, nephropathy or MACE, based on the identification of one or more aforementioned genetic features. Also described are combinations and kits for carrying out the above-described methods. | 05-31-2012 |
20140023635 | SINGLE NUCLEOTIDE POLYMORPHISMS AND GENES ASSOCIATED WITH T2D-RELATED COMPLICATIONS - The invention provides with means to predict, in subjects affected by type-2-diabetes (T2D), the probability of developing complications related to the disease. The invention involves (1) identification of genetic features such as single nucleotide polymorphisms (SNPs) for the establishment of a patient profile that can be used for prediction of complications associated with T2D. Signature profiles comprising a combination of SNPs which have greater predictive value for prognosticating particular types of complications, such as, stroke, myocardial infarction and kidney complications associated with T2D are further described. Compositions and kits that can be used with a set of complementary phenotypic markers to evaluate the risk for an individual affected by T2D to develop complications related to the disease and to evaluate the likelihood that an individual affected by type 2 diabetes type will benefit from treatments that collectively aim to reduce the risk of developing such complications. | 01-23-2014 |
Stephen Macmahon, Pymont AU
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20120065075 | METHOD OF DETERMINING A PREDISPOSITION TO ATRIAL FIBRILLATION (AF) IN A SUBJECT - The present invention concerns a method of determining a predisposition to atrial fibrillation (AF) in a subject comprising: determining the presence of at least one copy of a risk allele from at least one polymorphic marker in a sample from the subject, wherein the presence of at least one copy of the risk allele is indicative of a predisposition to AF, and wherein said at least one polymorphic marker is: a) rs4674485; b) rs1466560; c) rs1880039; d) rs3849387; e) rs7039; f) rs2952860; g) rs9312515; h) rs1897527; i) rs2299277; j) rs2418828; k) rs2385833; l) rs6717960; m) rs10510266; or n) a substitute polymorphic marker in linkage disequilibrium with any one of the polymorphic markers of a) to m). Also described are kits for determining a predisposition to atrial fibrillation (AF). | 03-15-2012 |