Patent application number | Description | Published |
20100261709 | PYRIDAZINONE DERIVATIVES AS PARP INHIBITORS - The present invention relates to compounds of formula (I): and pharmaceutically acceptable salts or tautomers thereof which are inhibitors of poly(ADP-ribose)polymerase (PARP) and thus useful for the treatment of cancer, inflammatory diseases, reperfusion injuries, ischaemic conditions, stroke, renal failure, cardiovascular diseases, vascular diseases other than cardiovascular diseases, diabetes mellitus, neurodegenerative diseases, retroviral infections, retinaldamage, skin senescence and UV-induced skin damage, and as chemo- or radiosensitizers for cancer treatment. | 10-14-2010 |
20110183989 | SATURATED BICYCLIC HETEROCYCLIC DERIVATIVES AS SMO ANTAGONISTS - The present invention relates to compounds of formula I: and pharmaceutically acceptable salts or tautomers thereof which are inhibitors of the Sonic Hedgehog pathway, in particular Smoantagonists. Thus the compounds of this invention are useful for the treatment of diseases associated with abnormal hedgehog pathway activation, including cancer, for example basal cell carcinoma, medulloblastoma, prostate, pancreatic, breast, colon, bone and small cell lung cancers, and cancers of the upper GI tract. | 07-28-2011 |
20110201657 | AMIDE SUBSTITUTED INDAZOLE AND BENZOTRIAZOLE DERIVATIVES AS POLY(ADP-RIBOSE)POLYMERASE (PARP) INHIBITORS - The present invention relates to compounds of formula (I) and pharmaceutically acceptable salts or tautomers thereof which are inhibitors of poly (ADP-ribose) polymerase (PARP) and thus useful for the treatment of cancer, inflammatory diseases, reperfusion injuries, ischemic conditions, stroke, renal failure, cardiovascular diseases, vascular diseases other than cardiovascular diseases, diabetes, neurodegenerative diseases, retroviral infection, retinal damage or skin senescence and UV-induced skin damage, and as chemo- or radiosensitizers for cancer treatment. | 08-18-2011 |
Patent application number | Description | Published |
20080215921 | Method, System and Computer Program for Performing Regression Tests Based on Test Case Effectiveness | 09-04-2008 |
20090106597 | Automatically Populating Symptom Databases for Software Applications - A solution is proposed for populating a symptom collection—such as a symptom database—for a software application. The symptom collection includes an indication of a set of symptoms; each symptom consists of an undesired behavior of the software application, which symptom is due to each one of a set of corresponding problems of the software application (resulting from a misuse thereof). The symptom database also includes an indication of an explanation of each problem. A corresponding method involves performing a test of the software application for verifying a correctness of the software application. The symptom collection is then populated according to a result of the test. | 04-23-2009 |
20090112704 | MANAGEMENT TOOL FOR EFFICIENT ALLOCATION OF SKILLS AND RESOURCES - A method for identifying a user having computer skills substantially in accordance with a predetermined skill set. The method may include identifying one or more users, identifying one or more computer skills of the user, and monitoring computer usage of the user to dynamically determine a proficiency level of the user with respect to the computer skill. Embodiments of the method may further include storing the proficiency level in a user profile for the user, and correlating the user profile with a predetermined skill set to identify one or more users having computer skills that best match the predetermined skill set. | 04-30-2009 |
20090164974 | QUALITY MEASURE TOOL FOR A COMPOSITE APPLICATION - A method for estimating a quality measure of a composite application is presented. The method may include receiving a set of sequence diagrams describing interactions between pairs of components in a composite application. Each sequence diagram may describe a functional use case of the composite application. Component quality metrics may also be received, such that each component quality metric corresponds to a component of the composite application. A quality estimation may be calculated for each use case of the composite application. The quality estimation may be determined as a function of one or more of the component quality metrics. A quality measure of the composite application may then be calculated as a function of the quality estimation for each use case. The quality measure of the composite application may be output. | 06-25-2009 |
20100064035 | METHOD AND SYSTEM FOR SHARING PERFORMANCE DATA BETWEEN DIFFERENT INFORMATION TECHNOLOGY PRODUCT/SOLUTION DEPLOYMENTS - A method and system for dynamically sharing performance information among multiple computing nodes. One implementation involves dynamically obtaining performance information from deployments of an information technology (IT) product/solution at said computing nodes, and transmitting the obtained performance information to a server over a communication network for storing the obtained performance information in a knowledge database. The server operates to dynamically determine new configuration information based on the information in the database, store the new configuration in the database, and provide the new configuration information to said deployments by transmitting the new configuration information over the network. | 03-11-2010 |
20120030214 | Facilitating Object Searches in Virtual Worlds - A mechanism is provided for facilitating object search in a virtual world environment where each object is defined by a plurality of attributes and the search is performed on any attributes of the object however is not limited to a 3-D search. The co-ordinate location of each object in the virtual world is also provided in the search result and the range within which to perform the search may also be specified. Optionally, the user has the ability to teleport/transport to the location of the object using the search result. | 02-02-2012 |
20120079083 | Sharing Performance Data Between Different Information Technology Product/Solution Deployments - A method and system for dynamically sharing performance information among multiple computing nodes. One implementation involves dynamically obtaining performance information from deployments of an information technology (IT) product/solution at said computing nodes, and transmitting the obtained performance information to a server over a communication network for storing the obtained performance information in a knowledge database. The server operates to dynamically determine new configuration information based on the information in the database, store the new configuration in the database, and provide the new configuration information to said deployments by transmitting the new configuration information over the network. | 03-29-2012 |
20130073560 | Facilitating Object Searches in Virtual Worlds - A mechanism is provided for facilitating object search in a virtual world environment where each object is defined by a plurality of attributes and the search is performed on any attributes of the object however is not limited to a 3-D search. The co-ordinate location of each object in the virtual world is also provided in the search result and the range within which to perform the search may also be specified. Optionally, the user has the ability to teleport/transport to the location of the object using the search result. | 03-21-2013 |