Serena
Serena Altilia, Columbia, SC US
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20140199708 | CELL-BASED METHODS FOR MEASURING ACTIVITY OF A PROTEIN INHIBITOR - The invention provides a method for determining the activity of an inhibitor of a target protein that has a deleterious effect on cell growth. The principle of the claimed method is that a compound that inhibits the function of an overexpressed protein will relieve the detrimental effect of such overexpression in a concentration-dependent manner, thereby allowing the determination of the activity of the compound in inhibiting its target protein in live cells. | 07-17-2014 |
Serena Badran-Louca, Raleigh, NC US
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20090006811 | Method and System for Expanding a Conditional Instruction into a Unconditional Instruction and a Select Instruction - A method of expanding a conditional instruction having a plurality of operands within a pipeline processor is disclosed. The method identifies the conditional instruction prior to an issue stage and determines if the plurality of operands exceeds a predetermined threshold. The method expands the conditional instruction into a non-conditional instruction and a select instruction. The method further executes the non-conditional instruction and the select instruction in separate pipelines. | 01-01-2009 |
Serena Bencivenni, Cento (fe) IT
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20160024009 | Novel Sulfonamide TRPA1 Receptor Antagonists - The invention discloses compounds of Formula (I). The compounds of formula (I) are TRPA1 antagonists and are useful as active ingredients of pharmaceutical compositions for the treatment of pain and other conditions ameliorated by the inhibition of TRPA1 receptors. | 01-28-2016 |
Serena Bertarione, Baldissero Torinese (torino) IT
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20130255997 | PROCESSES FOR PRODUCING CONDUCTIVE AND/OR PIEZORESISTIVE TRACES ON POLYMERIC SUBSTRATES - Process for producing conductive and/or piezoresistive traces in a non-conductive polymeric substrate through laser irradiation, characterised in that said substrate is a composite polymeric material, comprising the matrix of a polymer not susceptible to carbonisation through laser irradiation and a dispersed phase comprising carbon nano fibres and/or nanotubes. | 10-03-2013 |
Serena Biella, Milano IT
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20130260156 | SURFACE COATING WITH PERFLUORINATED COMPOUNDS AS ANTIFOULING - The present invention relates to the use of perfluorinated compounds as a surface coating to counteract the formation of fouling. The present invention also relates to a method for producing a surface coating capable of preventing the formation of fouling, this method comprising the application of a polar solution of a perfluorinated compound followed by a heat cycle conducted at controlled temperatures. | 10-03-2013 |
Serena Cagnoni, Mestrino (pd) IT
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20140034579 | METHOD FOR TREATING DRINKING WATER BY MEANS OF A REPLACEABLE CARTRIDGE FILTERING SYSTEM - A method for treating drinking water by modifying the ion concentration in the filtered water by means of a replaceable cartridge filtering system comprises: —defining a plurality of types of water to be filtered on the basis of chemical and physical features of the water to be treated; —defining a plurality of classes of filtered water to be obtained with the filtering system on the basis of chemical and physical features of the filtered water; —providing a plurality of filter cartridges containing a filtering material based on a mixture of two or more ion exchange resins, the mixture being formed from predetermined proportions of the two or more resins, each cartridge of the plurality of cartridges having a different mixture of the two or more resins and being capable of retaining ions from, and/or releasing ions into, the water filtered in the filtration process; —correlating one or more of the classes of filtered water with each cartridge of the plurality of cartridges for each type of water to be filtered; —selecting a cartridge from the plurality of cartridges in order to obtain a desired class of filtered water on the basis of a specified type of water to be filtered. | 02-06-2014 |
Serena Coiai, Pontasserchio IT
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20090215963 | Thermoplastic elastomeric material and process for its manufacturing - A thermoplastic elastomeric material includes a vulcanized rubber in a subdivided form surface-grafted with at least one vinyl polymer, wherein the amount of the surface-grafted vinyl polymer is not lower than 60% by weight, preferably not lower than 70% by weight, more preferably not lower than 80% by weight, with respect to the total weight of the surface-grafted vinyl polymer and the vulcanized rubber in a subdivided form. | 08-27-2009 |
Serena Danti, Pisa IT
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20120121712 | CELLULAR ELECTRIC STIMULATION MEDIATED BY PIEZOELECTRIC NANOTUBES - Piezoelectric nanotransducers for use in an in vivo treatment of cell stimulation through electrical stimulation are described. The nanotransducers are localized in a target site, and an electrical stimulus is induced in the same site through external stimulation of the nanotransducers by ultrasonic waves. | 05-17-2012 |
Serena David, Marlborough, MA US
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20140315211 | METHODS FOR SUPPRESSION PCR - Provided herein are approaches for the detection, identification, and/or selective amplification of specific target species or target variants of nucleic acid sequences, even within an excess of unwanted similar sequences or variants. These approaches include methods, assays, and kits for suppression PCR that require, in part, DNA polymerase that lacks 5′-3′ exonuclease activity, and a PCR primer, termed a forward selective primer or a nunchaku primer. The methods, assays, and kits provided herein are useful for a wide variety of applications, including cancer screening assays and kits, personalized screening assays, SNP (single nucleotide polymorphism) genotyping and identification, and downstream applications such as next generation high-throughput genomic sequencing and library construction. | 10-23-2014 |
Serena Debo, Mainz DE
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20100035267 | Detection of Individual T-Cell Reaction Patterns Against Tumor-Associated Antigens (TAA) in Tumor Patients as a Basis for the Individual Therapeutic Vaccination of Patients - The present invention relates to a method for identifying the preferential target antigens of antitumoural T-cells of a tumour patient, comprising: a) providing T-cells from the blood of at least one tumour patient, b) providing dendritic cell (DCs) and/or B-lymphocytes (BLCs) that are autologous for said tumour patient, wherein said DCs and BLCs were transfected beforehand with a selection of mRNAs encoding for T-cell-immunogenic tumour-associated antigens (TAA), and express these, c) contacting said T-cells with the DCs and/or BLCs, d) identifying of those T-cells that recognize antigens of the DCs and/or BLCs, and e) identifying of the preferential target antigens of antitumoural T-cells of the at least one tumour patient on the basis of the T-cells that recognize antigens of the DCs and/or BLCs. The method can furthermore comprise the expansion of the T-cells that recognize the antigens of the DCs and/or BLCs. The present invention furthermore relates to a method for producing an individualized tumour vaccine or individualized tumour therapeutic, as well as corresponding methods for treating a tumourous disease using the individualised tumour vaccine or individualised tumour therapeutic. | 02-11-2010 |
Serena Deiana, Aberdeen GB
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20100184752 | PHENOTHIAZINE COMPOUNDS FOR TREATING MILD COGNITIVE IMPAIRMENT - The present invention relates generally to methods and materials based on diaminophenothiazines for use in the treatment of Mild Cognitive Impairment (MCI). | 07-22-2010 |
Serena Di Cosimo, Boville Ernica IT
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20120059005 | COMBINATION OF (A) A PHOSPHOINOSITIDE 3-KINASE INHIBITOR AND (B) AN ANTIDIABETIC COMPOUND FOR USE IN THE TREATMENT OF PROLIFERATIVE DISEASES - The invention relates to a pharmaceutical combination which comprises (a) a phosphoinositide 3-kinase inhibitor compound and (b) an insulin sensitivity enhancer compound for the treatment of a proliferative disease, especially a solid tumor disease; a pharmaceutical composition comprising such a combination; the use of such a combination for the preparation of a medicament for the treatment of a proliferative disease; a commercial package or product comprising such a combination as a combined preparation for simultaneous, separate or sequential use; and to a method of treatment of a warm-blooded animal, especially a human. | 03-08-2012 |
Serena Fabbroni, Medicina IT
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20110262356 | Active Particles for Bio-Analytical Applications and Methods for Preparation Thereof - Luminescent and/or electroactive nanoparticles suitable for MRI (Magnetic Resonance Imaging) and/or PET (Positron Emission Tomography) are prepared by mixing luminescent or electroactive compounds and ethyl oxide/propyl oxide block-copolymers in an organic solvent, which is thereafter evaporated in order to obtain a residue; and by hydrolyzing-condensating tetraalkoxysilanes in an aqueous solution in the presence of the residue; the obtained nanoparticles show no or a negligible release of the luminescent or electroactive compounds and are useful for bio-analytic and bio-medic applications. | 10-27-2011 |
Serena Hilal, Rancho Santa Margarita, CA US
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20110005661 | Medical Tubing Having Variable Characteristics and Method of Making Same - The invention primarily is directed to a medical tubing adapted for insertion into a body tissue or cavity and method of manufacturing different variations of the tubing along a length of the tubing. The tubing comprises a plurality of individual, discrete, generally ring-shaped elements arranged in series and fused or bonded together forming a continuous tubular structure. The ring-shaped elements may be formed of a thermoplastic or a thermoset material. The ring-shaped elements may include plastic rings, metallic rings, un-reinforced plastic rings and/or metal reinforced plastic rings assembled along the length of the tubular structure to provide variable flexibility and kink-resistance. The tubular structure may have a cross-section of any geometric shape and it may be bent, twisted or curved without kinking. The ring-shaped elements may have different flexural modulus. The ring-shaped elements may include a combination of flexible and rigid ring-shaped elements assembled along different portions or sections of the tubular structure. The ring-shaped elements may be metallic and may be bonded with a resilient, flexible elastomeric adhesive, wherein the ring-shaped elements may have different lengths and may be fused closer or further apart to one another depending on the characteristics of a portion or section of the tubing. In another aspect of the invention, the medical tubing may further comprise a secondary lumen and a pull wire to control the tubular structure. The ring-shaped elements may be truncated to provide a bending bias. In another aspect of the invention, the ring-shaped elements may vary in diameter and/or composition in different portions or sections of the tubular structure. In yet another aspect of the invention, some of the ring-shaped elements may be radiopaque, or the ring-shaped elements may comprise of different colors to operate as indicators along the tubular structure. | 01-13-2011 |
Serena Mercanti, Ancona IT
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20100324594 | DEVICE FOR COSMETIC TREATMENT OF HAIRY BODY PARTS - The present invention relates to a device ( | 12-23-2010 |
Serena Omodeo Sale', Milano IT
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20090277543 | PRODUCTION SYSTEM OF WELDABLE AND STAINLESS TUBULAR STRUCTURES WITH HIGH MECHANICAL STRENGTH AND PRODUCT OBTAINED THEREFROM - A production system weldable and stainless tubular structures with high mechanical strength and related obtained product, particularly for making tubular elements in cold-drawn stainless steel, workable at different thicknesses and shapes, provided with high performances in terms of mechanical characteristics and weldability, for the construction of light and ultralight structural frames destined for a dynamic use. It comprises a creation step of a tip for making the end of the tube smaller, so that it can pass through the drawing equipment and be coupled for drawing, a step of annealing heat treatment for softening the material and making it deformable. The system provides a mechanical test for evaluating the mechanical characteristics of the material and a metallography for viewing the structure of the material and evaluating if it comes within pre-established parameters for the drawing and a chemical preparation of the surfaces, for lubricating the contact surfaces of the tube with the drawing equipment and for avoiding seizures during the drawing. The preceding steps are repeated until the desired thickness. A step of final heat treatment follows, for reforming the structure of the steel and for fixing the desired final characteristics. Finally, a step of straightening is carried out for make the drawn and furnace-treated tube rectilinear, and a step of passivation for inducing a compact oxide patina ensuring its resistance to corrosion. The cutting, control and packaging operations follow. | 11-12-2009 |
Serena Passanisi, Caltanissetta (cl) IT
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20130324796 | LOCOMOTION DEVICE FOR ENDOSCOPIC APPLICATIONS AND RELATED METHODS - A locomotion device and related methods for navigation into an intracorporeal cavity such as a gastrointestinal tract are described. The locomotion device is based upon rotating pinching organs, associated actuators, and transmission systems wherein the rotating pinching organs are placed side by side and rotate in an opposite direction in order to draw and retain a tissue portion and establish an anchoring point of the locomotion device onto the substratum. | 12-05-2013 |
Serena Pellegatta, Olginate IT
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20100071081 | METHOD FOR STIMULATING DENDRITIC CELLS AND CELL PRODUCT THUS OBTAINED FOR THE AUTOLOGOUS IMMUNOTHERAPY OF SOLID HUMAN TUMOURS - In the ex vivo stimulation method of dendritic cells, the stimulation occurs with the lysate of tumour spheres (TS) of the solid tumours. | 03-18-2010 |
Serena Pezzia, Casalpusterlengo IT
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20100130399 | SELF ADHESIVE HARD SURFACE CLEANING COMPOSITION - The present invention relates to hard surface cleaning compositions, and their use. It is an object of the present invention to provide a hard surface cleaning composition providing hygiene to a hard surface, whilst being easily positioned onto a hard surface; even a wet surface. The present invention provides a hard surface cleaning composition, which is at least partially transparent or translucent, characterized in that it comprises a surfactant system forming a liquid crystalline phase in the presence of water and biocide material. | 05-27-2010 |
20100162474 | SELF ADHESIVE HARD SURFACE CLEANING BLOCK - The present invention relates to self adhesive hard surface cleaning blocks, and their use. It is an object of the present invention to provide a detergent block that can be easily positioned onto a hard surface; even a wet surface. It is a further object of the invention to provide a detergent block that rinses away in a number of flushes, and does not leave behind any residue that cannot be easily removed with e.g. a toilet brush. We have found that a hard surface cleaning block comprising surfactants forming a liquid crystalline phase upon contact with water meet the objects of the invention. | 07-01-2010 |
Serena Pillozzi, Florence IT
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20120309704 | COMPOSITIONS FOR TREATMENT OF CHEMORESISTANT AND/OR POTENTIALLY CHEMORESISTANT LEUKAEMIAS - This description applies to pharmaceutical compositions comprising a mixture comprising one or more hERG1 channel blockers in combination with one or more compounds for anticancer therapy for use in the treatment of chemoresistant or potentially chemoresistant leukaemias and in vitro systems for the screening of substances suitable for use in the treatment of chemoresistant or potentially chemoresistant leukaemias. | 12-06-2012 |
Serena Porrazzo, Eindhoven NL
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20140070972 | Circuit For Digitizing A Sum Of Signals - A circuit for digitizing a sum of a first input signal and a plurality of second input signals has a passive adder that sums the second input signals and outputs a summation signal and a multi-bit quantizer circuit. The quanitzer circuit compares the summation signal at a first comparator input with a signal at a second comparator input, which is derived from the first input signal and has an appropriate polarity so that the difference between the summation signal and the signal at the second comparator input is indicative of the sum of the first input signal and the plurality of second input signals. The comparator also produces a comparator output signal based on the sum of the first input signal and the plurality of second input signals. The quantizer circuit also has a control logic block for determining a multi-bit representation of the sum from the comparator output signal. | 03-13-2014 |
Serena Reggi, Piacenza Pc IT
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20100168006 | IN-PLANT PRODUCTION OF DIMERIC AND/OR OLIGOMERIC (COMPRISING THREE OR MORE UNITS) FORMS OF HUMAN APO A-1 PROTEIN MUTEINS - The present invention encompasses a method for the production of Apolipoproteins in dimeric and/or oligomeric forms (comprising three or more units) of muteins of the human ApoA-1 protein in plant seeds, novel variants of these proteins having an increased stability and capacity to transport cholesterol compared to the native ApoA-1 protein, expression systems for the production thereof, plants transformed capable of producing said proteins in seeds in dimeric and/or oligomeric forms, and nutraceutical derivatives of these plants. | 07-01-2010 |
Serena Tongiani, Cranford, NJ US
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20090062397 | COMPOUNDS AND METHODS FOR ENHANCING SOLUBILITY OF FLORFENICOL AND STRUCTURALLY-RELATED ANTIBIOTICS USING CYCLODEXTRINS - The relatively low solubility of florfenicol (FEC) in water (1.3 mg/mL) limits its use in medicated drinking water systems for treatment of pulmonary disease of swine and poultry. Current formulations use a high volume organic solvent to reach the required FFC concentration of 13.5 mg/mL in an automated proportioner mixing tank system, with practical disadvantages for the users in the field. This invention relates to the effects of complex formation with natural and modified cyclodextrins on the aqueous solubility of FFC and antibiotics of related structure. Furthermore, this invention relates to the effects of polyethylene glycol (PEG-300) as a co-solvent in an FFC-cyclodextrin system to achieve the required FFC dose in the mixing tank system and to avoid high volumes of the organic solvent. | 03-05-2009 |
20090156683 | FAST RELEASE SOLID FORMULATION, PREPARATION AND USE THEREOF - The present invention relates to a chemically stable formulation of florfenicol, (and structurally related compounds) in compositions such as soluble blended powders, granules, fast-dissolving tablets or pellets suitable for rapid release of the drug in water, and to methods and kits for treating animals with aqueous compositions including florfenicol. | 06-18-2009 |
Serena Tordin, Settimo Torinese DE
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20150032359 | METHOD OF CORRECTING OPERATING SET POINTS OF AN INTERNAL COMBUSTION ENGINE - A method of correcting operating set points of an internal combustion engine is disclosed. The method includes predetermining an oxygen sensor time correction factor representative of a delay between a combustion event of a fuel quantity injected into a cylinder of the engine and a measurement in the exhaust pipe of an air-to-fuel ratio produced by said combustion event; calculating a fuel injection error quantity as a difference between a nominal fuel quantity and an estimated fuel quantity injected into the cylinder, the nominal fuel quantity being determined for an injection that precedes the measurement of an air-to-fuel ratio value by the oxygen sensor time correction factor, the estimated fuel quantity being determined as a function of an air mass flow value and of the measured air-to-fuel ratio value; and correcting the operating set points of the internal combustion engine using the calculated fuel injection error quantity. | 01-29-2015 |
Serena Tordin, Settimo Torinese CH
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20150051814 | METHOD OF CONTROLLING A FUEL INJECTION - A method of controlling an amount of fuel to be injected by a fuel injector into a cylinder of an internal combustion engine is disclosed. A map stores values of a fuel injection quantity drift of said injector. A fuel injection quantity drift is estimated and stored in a corresponding map point to a current engine operating point. A set of map points whose distance from said corresponding map point is smaller than a given distance are selected. All map points of the set of map points are modified by multiplying their entries by a radial weighing factor. The amount of fuel to be injected by the fuel injector to be the requested amount of fuel is corrected by means of the corresponding entry of the map. | 02-19-2015 |