Zerbe
Horst Zerbe, Hudson CA
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20090214640 | DELAYED RELEASE PHARMACEUTICAL ORAL DOSAGE FORM AND METHOD OF MAKING SAME - The present invention relates to a delayed release pharmaceutical oral dosage form and method of making same. The delayed release dosage form comprises one or more active ingredients within a granulated composition, which further comprises one or more excipients selected from the group of solid aliphatic alcohols, fatty acid esters, mixtures of esters of saturated fatty alcohols and saturated fatty acids, natural waxes, synthetic waxes, hydrogenated castor oil, hydrogenated vegetable oil, gums, and mixtures thereof; and one or more polymers or copolymers exhibiting a pH-dependent solubility. The present invention also related to method of making these delayed release dosage form. | 08-27-2009 |
20110136815 | SOLID ORAL FILM DOSAGE FORMS AND METHODS FOR MAKING SAME - Improved pharmaceutical solid oral film dosage forms for the buccal and/or sublingual delivery of pharmaceutical, nutraceutical or cosmetic ingredients are endowed with instant hydration potential and complete dissolution potentially enabling the active ingredient to become immediately available for enhanced buccal and/or sublingual absorption and/or reduced absorption through the gastrointestinal route. The improved delivery systems for solubilizing and stabilizing pharmaceutically active ingredients exhibit enhanced stability by the use of a combination of crystallization inhibitors, which together can maintain the active ingredient in a desired plurality of particles in an effective size range within a polymeric film matrix. | 06-09-2011 |
20110263606 | SOLID ORAL DOSAGE FORMS COMPRISING TADALAFIL - Improved pharmaceutical solid oral dosage forms for the buccal and/or sublingual delivery of Tadalafil. The improved delivery systems for solubilizing and stabilizing pharmaceutically active ingredients exhibit enhanced methods of preparation by the use improved solubilization systems which can maintain the Tadalafil in a buccal and/or sublingual oral dosage form or a polymeric film matrix that provides improved bioavailability and/or absorption of Tadalafil. | 10-27-2011 |
20130137698 | SOLID ORAL FILM DOSAGE FORMS AND METHODS FOR MAKING SAME - Improved pharmaceutical solid oral film dosage forms for the buccal and/or sublingual delivery of pharmaceutical, nutraceutical or cosmetic ingredients are endowed with instant hydration potential and complete dissolution potentially enabling the active ingredient to become immediately available for enhanced buccal and/or sublingual absorption and/or reduced absorption through the gastrointestinal route. The improved delivery systems for solubilizing and stabilizing pharmaceutically active ingredients exhibit enhanced stability by the use of a combination of crystallization inhibitors, which together can maintain the active ingredient in a desired plurality of particles in an effective size range within a polymeric film matrix. | 05-30-2013 |
Horst G. Zerbe, Hudson CA
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20110028431 | ORAL MUCOADHESIVE DOSAGE FORM - A direct compression formulation suitable for preparing buccal and/or sublingual and dosage forms incorporates a combination of a non-ionic polymeric solubility enhancer, a mucoadhesive polymer, a filler, a disintegrant, and a pharmaceutically active agent. Cannabinoid-cyclodextrin complexes exhibiting an improved property selected from improved stability, higher product yield and improved product uniformity may be obtained by complexing the cannabinoid with the cyclodextrin in a liquid medium containing an antioxidant. To enhance stability, product yield and/or product uniformity, complexing may be done while the liquid medium is in contact with an atmosphere having a very low oxygen content. The resulting complexes may be combined with decomplexing agents and/or dispersed in a matrix material comprised of a hydrogel-forming polymer to provide enhanced absorption of the cannabinoid through oral mucosa and reduced ingestion of the cannabinoid as compared with known commercially available cannabinoid-containing oral dosage forms. | 02-03-2011 |
20140065217 | MULTILAYER TABLET - A multilayer oral dosage form that provides controlled release of an active compound includes a non-erodible core containing a pharmaceutically active compound and/or a nutritionally active compound, and at least one release-modulating layer laminated to each side of the core layer. The dosage form can be prepared using simple, inexpensive tablet compression techniques. | 03-06-2014 |
Horst G. Zerbe, Quebec CA
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20150038540 | INSTANTLY WETTABLE ORAL FILM DOSAGE FORM WITHOUT SURFACTANT OR POLYALCOHOL - An instantly wettable and rapidly disintegrating oral film dosage form without a surfactant and without a polyalcohol was achieved by combining at least one water soluble polymer that is not a copolymer of vinylpyrrolidone, at least one active agent, a copolymer of vinylpyrrolidone and titanium dioxide. In certain embodiments, the film comprises hydroxypropyl cellulose or a combination of hydroxypropyl cellulose and a polymer or copolymer of vinylpyrrolidone or a substituted vinylpyrrolidone as the water soluble polymer(s). A plasticizer, and optional additives selected from synthetic sweeteners, natural sweeteners, flavorants, antioxidants, colorants, and opacifiers, can be added to the disclosed film oral dosage forms. | 02-05-2015 |
Horst Georg Zerbe, Green Pond, NJ US
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20120114705 | WATER SOLUBLE FILM FOR ORAL ADMINISTRATION WITH INSTANT WETTABILITY - A composition containing therapeutic agents and/or breath freshening agents for use in the oral cavity is disclosed. The carrier comprises water-soluble polymers in combination with certain ingredients and provides a therapeutic and/or cosmetic effect. The film is coated and dried utilizing existing coating technology and exhibits instant wettability followed by rapid dissolution/disintegration upon administration in the oral cavity. | 05-10-2012 |
James S. Zerbe, Redmond, WA US
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20090177567 | MOBILE APPLICATION MONITORING SYSTEM - A method and system to test, monitor, and share revenue associated with third-party software applications operating on mobile devices over a network operator's wireless network. An application may be tested by the mobile application monitoring system to simulate the expected load of the application on a mobile device and the wireless network utilized by the mobile device, and to determine any services utilized by the application. Based on the simulation, the system determines a compensation arrangement under which revenue associated with the application will be shared between the network operator and the application provider. In some embodiments, the compensation arrangement is determined from a variable reward table. Revenue is shared inversely with an application's impact on customers and on the network operator. | 07-09-2009 |
20100003923 | MOBILE APPLICATION MONITORING SYSTEM - A method and system to test, monitor, audit and share revenue associated with third-party software applications operating on mobile devices over a network operator's wireless network. An application may be tested by the mobile application monitoring system to simulate the expected load of the application on a mobile device and the wireless network utilized by the mobile device, and to determine any services utilized by the application. Based on the simulation, the system determines a compensation arrangement under which revenue associated with the application will be shared between the network operator and the application provider. Revenue is shared inversely with an application's impact on customers and on the network operator. Modifications may be made to the compensation arrangement by the system to cause the revenue share or other compensation value to increase or decrease based on non-performance-related features or consequences that are identified by the system. | 01-07-2010 |
Jeffrey N. Zerbe, Oro Valley, AZ US
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20110220001 | SUBMERSIBLE TRANSPORT CANISTER AND METHODS FOR THE USE THEREOF - Embodiments of a submersible transport canister, and embodiments of using a submersible transport canister, are provided. In one embodiment, the submersible transport canister includes a pressure vessel having a storage cavity configured to store at least one item therein, a cap movable to a closed position wherein the cap sealingly engages the pressure vessel, and a diver-adjustable buoyancy system configured to be coupled to the pressure vessel. When coupled to the pressure vessel, the diver-adjustable buoyancy system is configured to displace a volume of water to achieve a substantially neutral buoyancy during underwater transport of the item within the submersible transport canister. | 09-15-2011 |
20110253025 | REMOTELY-TRIGGERED SUBMERGED LAUNCH CANISTERS AND METHODS RELATING TO THE USAGE AND PREPARATION THEREOF - Embodiments of a method are provided for remotely deploying a waterborne object utilizing a submerged launch canister including a remotely-triggered deployment system. In one embodiment, the method includes the steps of placing the remotely-triggered deployment system in a launch-ready state, and positioning the submerged launch canister within a body of water. In a further embodiment wherein the waterborne object assumes the form of an Unmanned Underwater Vehicle, the method includes the step of transmitting a wireless signal to the remotely-triggered deployment system to initiate launch of the Unmanned Underwater Vehicle after the submerged launch canister has been positioned on the seafloor. | 10-20-2011 |
20110253026 | REMOTELY-TRIGGERED SUBMERGED LAUNCH CANISTERS - Embodiments of a submerged launch canister are provided for the remotely-initiated deployment of a waterborne object. In one embodiment, the submerged launch canister includes a pressure vessel and a remotely-triggered deployment system. The pressure vessel has an open end portion and a storage cavity configured to receive the waterborne object therein. The remotely-triggered deployment system is configured to propel the waterborne object from the storage cavity, through the open end portion, and into a body of water when remotely triggered. | 10-20-2011 |
20120068009 | SUBMERSIBLE TRANSPORT AND LAUNCH CANISTER - Embodiments of a submersible transport and launch canister are provided for use by a diver in the deployment of an airborne object. In one embodiment, the submersible transport and launch canister includes a pressure vessel having an open end portion and a storage cavity configured to receive the airborne object therein. A diver-actuated cap is movable between an open position and a closed position in which the diver-actuated cap sealingly engages the open end portion. A propellant device is fluidly coupled to the storage cavity and is configured to propel the airborne object from the storage cavity and through the open end portion when the propellant device is actuated by the diver. | 03-22-2012 |
20120068010 | SUBMERSIBLE TRANSPORT AND LAUNCH CANISTER AND METHODS FOR THE USE THEREOF - Embodiments of a method for deploying an airborne object are provided utilizing a submersible transport and launch canister of the type that includes a pressure vessel in which the airborne object is stored and a cap which sealingly engages the pressure vessel. In one embodiment, the method includes the steps of positioning an end portion of the pressure vessel above the surface level of a body of water, opening the cap, and launching the airborne object from the pressure vessel while in the body of water. | 03-22-2012 |
Jeffrey N. Zerbe, Verch Way, AZ US
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20110073707 | METHODS AND APPARATUS FOR MARINE DEPLOYMENT - Methods and apparatus for marine deployment according to various aspects of the present invention may operate in conjunction with a floatable housing adapted to be deployed by a marine vehicle. The floatable housing may be adapted to be launched from a marine vehicle and rise to the surface. Assets, such as an unmanned aerial vehicle, may be deployed from the surfaced floatable housing. | 03-31-2011 |
Jeffrey N. Zerbe, Valley, AZ US
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20090107386 | METHODS AND APPARATUS FOR MARINE DEPLOYMENT - Methods and apparatus for marine deployment according to various aspects of the present invention may operate in conjunction with a floatable housing adapted to be deployed by a marine vehicle. The floatable housing may be adapted to be launched from a marine vehicle and rise to the surface. Assets, such as an unmanned aerial vehicle, may be deployed from the surfaced floatable housing. | 04-30-2009 |
Philipp Zerbe, North Vancouver CA
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20130224809 | Diterpene Synthases And Method For Producing Diterpenoids - Provided herein are diterpene synthases (diTPS) and methods for producing diterpenoids. Also provided herein are nucleic acid sequences encoding diTPS, diTPS amino acid sequences, diTPS proteins, vectors, cells, transgenic organisms, uses, compositions, methods, processes, and kits thereof. | 08-29-2013 |
20150037854 | DITERPENE SYNTHASES AND METHOD FOR PRODUCING DITERPENOIDS - Provided herein are diterpene synthases (diTPS) and methods for producing diterpenoids. Also provided herein are nucleic acid sequences encoding diTPS, diTPS amino acid sequences, diTPS proteins, vectors, cells, transgenic organisms, uses, compositions, methods, processes, and kits thereof. | 02-05-2015 |
Robert L. Zerbe, Ann Arbor, MI US
RĂ¼diger Zerbe, Neuss DE
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20110186224 | METHOD AND DEVICE FOR DESCALING A METAL STRIP - A method and a device for descaling a metal strip, in which the metal strip is guided in a direction of conveyance through at least one plasma descaling unit in which it is subjected to a plasma descaling. The metal strip is subjected to an automatically controlled cooling process in a cooling unit following the plasma descaling in the one or more plasma descaling units in such a way that it has a well-defined temperature downstream of the cooling unit. | 08-04-2011 |
20110195200 | METHOD AND DEVICE FOR DESCALING A METAL STRIP - A method and a device for descaling a metal strip, in which the metal strip is guided in a direction of conveyance through at least one plasma descaling unit in which it is subjected to a plasma descaling. The metal strip is subjected to an automatically controlled cooling process in a cooling unit following the plasma descaling in the one or more plasma descaling units in such a way that it has a well-defined temperature downstream of the cooling unit. | 08-11-2011 |
Ruediger Zerbe, Neuss DE
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20090272319 | Apparatus For Hot-Dip Coating Of A Metal Strand - The present invention relates to an apparatus for hot-dip coating of a metal strand, in particular a steel strip, in which the metal strand ( | 11-05-2009 |
Walter Zerbe, Newmarket, NH US
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20100089605 | BACK BOX WITH POWER POCKET FOR IN-WALL ELECTRONIC COMPONENTS - A multi-part electrical/electronics enclosure that may be used for in-wall installation of intercom, home audio, lighting, HVAC or other automation controls and similar system components. The enclosure includes two major components including a back box, serving to enclose low voltage electronics, and a power pocket portion, fitting into at least one wall of the back box. The power pocket serves as an enclosure for high voltage alternating current electrical wire terminations, equipment connections, power supplies and the like. A trade separator fits between the back box and power pocket to completely enclose and isolate high voltage electrics from low voltage electronics. This solution provides maximize use of available space especially in retrofit applications. It also provides for servicing of electronics (disposed in back box) without accessing or servicing high voltage electrics in the power pocket. | 04-15-2010 |