Patent application number | Description | Published |
20090054979 | Phonatory Implant - The invention concerns a phonatory implant ( | 02-26-2009 |
20090118838 | Materials Useful for Support and/or Replacement of Tissue and the Use Thereof for Making Prostheses - The invention relates to a material providing support and/or replacement of living tissues and the use thereof for manufacturing prostheses. The material according to the invention comprises microparticles of a biomaterial coated with polyelectrolyte multilayers containing one or more biologically active products. | 05-07-2009 |
20090253099 | Method for Obtaining a Biocompatible Composite Implant - The invention concerns a method for obtaining a metal implant for open porosity tissue support and/or replacement, characterized in that it comprises the following steps: (i) selecting a mould, (ii) arranging in the mould a solid metal core ( | 10-08-2009 |
20100023125 | UNIVERSAL IMPLANT FOR THYROPLASTY - An implant being urged to be positioned between the thyroid cartilage ( | 01-28-2010 |
20110106251 | VALVE DEVICE INTENDED FOR BEING IMPLANTED IN A DYSFUNCTIONAL LARYNX OR A LARYNX PROSTHESIS - The present invention relates to a valve device designed to be implanted in a dysfunctional larynx or in a prosthetic larynx, said device comprising a distal portion forming an annular support structure and a central portion forming an obturator, characterized in that said obturator comprises i) a peripheral part forming a first valve integral with the annular support structure in a first hinge region, and ii) a central part forming a second valve integral with the first valve in a second hinge region. | 05-05-2011 |
Patent application number | Description | Published |
20110145170 | Financial Instrument Utilizing an Optional Benefit Election - According to one embodiment of the invention, a financial instrument includes an account with an account balance that changes over time, wherein at least part of the account balance may be discretionarily withdrawn and wherein the initial account balance is based upon an initial deposit; a guarantee that a beneficiary may periodically receive a transfer of an amount of money for the life of a first designated party, wherein the transfer may be due to withdrawal from the account or due to benefit payments made to the beneficiary, provided that the amount may vary based upon withdrawals from the account in excess of a particular limit; and an option to modify the guarantee such that upon election the beneficiary may periodically receive the transfer of the amount of money for the longer of the life of the first designated party and the life of a second designated party. | 06-16-2011 |
20140330590 | Asset-Based Adjustment of Premium Amounts for the Generation of an Annuity Based on a Pension Plan - According to one embodiment, a system includes one or more processors operable to determine a premium amount associated with a generation of an annuity based on a pension plan, and receive data indicative of a plurality of assets to be used towards a payment of the premium amount. The processors are further operable to, for each of one or more characteristics, receive data indicative of at least one threshold associated with the characteristic, determine whether at least a portion of the assets have a characteristic value that is above or below the threshold, and based on the determination, determine a non-conformance amount associated with the characteristic. The processors are further operable to, based on the non-conformance amount of each of the characteristics, adjust the premium amount, and communicate the adjusted premium amount for display. | 11-06-2014 |
Patent application number | Description | Published |
20090305392 | DEVICE FOR PROCESSING SAMPLES - Device for sample processing, particularly sample conditioning as well as for the preparation and/or optionally for implementing a sequential process for an analyte from a biological sample, said device comprising a module for receiving and/or outputting at least one sample vessel or process vessel, a module for transporting a process vessel, a module for sample conditioning and a module for initiating a sequential process for an analyte. The modules are divided into at least two units that each possesses a control system, and which are connected through a first data bus. | 12-10-2009 |
20140053503 | DEVICE FOR CLOSING A SAMPLE RECEPTACLE WITH A SPHERICAL CLOSURE ELEMENT - The invention relates to a device for closing a sample container with a spherical closing element, wherein the device has a storage container for a plurality of spherical closing elements, ejecting means for ejecting one of the closing elements through a discharge opening in a housing of the device, and means for limiting the forces exerted by the ejecting means on the closing element. | 02-27-2014 |
20140056784 | SAMPLE RECEPTACLE - The invention relates to a sample container, comprising a housing which forms a sample space for receiving a sample and has at least one circular opening which extends in a channel-shaped manner into the sample space, and further comprising a spherical closing element, wherein the diameter of the closing element only exceeds the diameter of the opening channel in at least one (closing) portion to such an extent that the closing element can be fixed in a force-locked manner by its largest circumference in the closing portion, wherein the spherical closing element is in contact with the housing, and the opening channel between the closing portion and the inner opening forms a protrusion which reduces the opening cross section of the opening channel with respect to the opening cross section in the closing portion. | 02-27-2014 |
Patent application number | Description | Published |
20100016783 | NON-INVASIVE SYSTEMS AND METHODS FOR IN-SITU PHOTOBIOMODULATION - Products, compositions, systems, and methods for modifying a target structure which mediates or is associated with a biological activity, including treatment of conditions, disorders, or diseases mediated by or associated with a target structure, such as a virus, cell, subcellular structure or extracellular structure. The methods may be performed in situ in a non-invasive manner by application of an initiation energy to a subject thus producing an effect on or change to the target structure directly or via a modulation agent. The methods may further be performed by application of an initiation energy to a subject in situ to activate a pharmaceutical agent directly or via an energy modulation agent, optionally in the presence of one or more plasmonics active agents, thus producing an effect on or change to the target structure. Kits containing products or compositions formulated or configured and systems for use in practicing these methods. | 01-21-2010 |
20110021970 | NON-INVASIVE ENERGY UPCONVERSION METHODS AND SYSTEMS FOR IN-SITU PHOTOBIOMODULATION - Products, compositions, systems, and methods for modifying a target structure which mediates or is associated with a biological activity, including treatment of conditions, disorders, or diseases mediated by or associated with a target structure, such as a virus, cell, subcellular structure or extracellular structure. The methods may be performed in situ in a non-invasive manner by placing a nanoparticle having a metallic shell on at least a fraction of a surface in a vicinity of a target structure in a subject and applying an initiation energy to a subject thus producing an effect on or change to the target structure directly or via a modulation agent. The nanoparticle is configured, upon exposure to a first wavelength λ | 01-27-2011 |
20120064134 | COLOR ENHANCEMENT UTILIZING UP CONVERTERS AND DOWN CONVERTERS - A light emitting composition including first color emitters and second color emitters. The first color emitters are configured to emit, upon exposure to an energy source, visible light at a target color in response to absorption of energy across a first band of wavelengths. The second color emitters are configured to emit, upon exposure to the energy source, visible light at the target color in response to absorption of energy across a second band of wavelengths. The light intensity observable at the target color is enhanced relative to reflected white light without emission from the first and second color emitters. The light emitting composition can be a part of a paint, an ink, a fabric, a thread, a road sign, a highway marking, an automobile, a boat, a plane, a reflector, a building product, a concrete product, an epoxy product, a jewelry product, colored contact lens, a candle product, a rubber product, a plastic product, or other colored surface. | 03-15-2012 |
20140243934 | NON-INVASIVE ENERGY UPCONVERSION METHODS AND SYSTEMS - Products, compositions, systems, and methods for modifying a target structure. The methods may be performed in a non-invasive manner by placing a nanoparticle having a metallic shell on at least a fraction of a surface in a vicinity of a target structure in a subject and applying an initiation energy thus producing an effect on or change to the target structure directly or via a modulation agent. The nanoparticle is configured, upon exposure to a first wavelength λ | 08-28-2014 |
20140272030 | INTERIOR ENERGY-ACTIVATION OF PHOTO-REACTIVE SPECIES INSIDE A MEDIUM OR BODY - A method and a system for producing a change in a medium. The method places in a vicinity of the medium an energy modulation agent. The method applies an initiation energy to the medium. The initiation energy interacts with the energy modulation agent to directly or indirectly produce the change in the medium. The energy modulation agent has a normal predominant emission of radiation in a first wavelength range outside of a second wavelength range (WR2) known to produce the change, but under exposure to the applied initiation energy produces the change. The system includes an initiation energy source configured to apply an initiation energy to the medium to activate the energy modulation agent. | 09-18-2014 |
20150202294 | USE OF PSORALEN DERIVATIVES AND COMBINATION THERAPY FOR TREATMENT OF CELL PROLIFERATION DISORDERS - Methods for the treatment of a cell proliferation disease or disorder in a subject, involving applying a psoralen derivative lacking a DNA cross-linking motif to cancer cells, applying a psoralen or a derivative thereof and lapatinib, or applying a psoralen or derivative thereof and neratinib, to a subject and further applying initiation radiation energy form an energy source. | 07-23-2015 |
20150251016 | NON-INVASIVE ENERGY UPCONVERSION METHODS AND SYSTEMS - Products, compositions, systems, and methods for modifying a target structure. The methods may be performed in a non-invasive manner by placing a nanoparticle having a metallic shell on at least a fraction of a surface in a vicinity of a target structure in a subject and applying an initiation energy thus producing an effect on or change to the target structure directly or via a modulation agent. The nanoparticle is configured, upon exposure to a first wavelength λ | 09-10-2015 |
Patent application number | Description | Published |
20120089180 | ADHESIVE BONDING COMPOSITION AND METHOD OF USE - A polymerizable composition includes at least one monomer, a photoinitiator capable of initiating polymerization of the monomer when exposed to light, and a phosphor capable of producing light when exposed to radiation (typically X-rays). The material is particularly suitable for bonding components at ambient temperature in situations where the bond joint is not accessible to an external light source. An associated method includes: placing a polymerizable adhesive composition, including a photoinitiator and energy converting material, such as a down-converting phosphor, in contact with at least two components to be bonded to form an assembly; and, irradiating the assembly with radiation at a first wavelength, capable of conversion (down-conversion by the phosphor) to a second wavelength capable of activating the photoinitiator, to prepare items such as inkjet cartridges, wafer-to-wafer assemblies, semiconductors, integrated circuits, and the like. | 04-12-2012 |
20140323946 | PHOSPHORS AND SCINTILLATORS FOR LIGHT STIMULATION WITHIN A MEDIUM - A system and method for light stimulation within a medium. The system has a reduced-voltage x-ray source configured to generate x-rays from a peak applied cathode voltage at or below 105 kVp, and a plurality of energy-emitting particles in the medium which, upon radiation from the x-ray source, radiate at a first lower energy than the x-ray source to interact with at least one photoactivatable agent in the medium. The method introduces the plurality of energy-emitting particles into the medium, radiates the energy-emitting particles in the medium with x-rays generated from a peak applied cathode voltage at or below 105 kVp; and emits a lower energy than the x-ray source to interact with the medium or with at least one photoactivatable agent in the medium. | 10-30-2014 |
20150246521 | ADHESIVE BONDING COMPOSITION AND METHOD OF USE - A polymerizable composition includes at least one monomer, a photoinitiator capable of initiating polymerization of the monomer when exposed to light, and a phosphor capable of producing light when exposed to radiation (typically X-rays). The material is particularly suitable for bonding components at ambient temperature in situations where the bond joint is not accessible to an external light source. An associated method includes: placing a polymerizable adhesive composition, including a photoinitiator and energy converting material, such as a down-converting phosphor, in contact with at least two components to be bonded to form an assembly; and, irradiating the assembly with radiation at a first wavelength, capable of conversion (down-conversion by the phosphor) to a second wavelength capable of activating the photoinitiator, to prepare items such as inkjet cartridges, wafer-to-wafer assemblies, semiconductors, integrated circuits, and the like. | 09-03-2015 |
Patent application number | Description | Published |
20090143571 | NOVEL GENES AND THEIR USE IN THE MODULATION OF OBESITY, DIABETES AND ENERGY IMBALANCE - The present invention relates generally to nucleic acid molecules encoding proteins associated with the modulation of obesity, diabetes and/or metabolic energy levels. More particularly, the present invention is directed to nucleic acid molecules and the recombinant and purified proteins encoded thereby and their use in therapeutic and diagnostic protocols for conditions such as obesity, diabetes and energy imbalance. The subject nucleic acid molecules and proteins and their derivatives, homologs, analogs, chemical equivalents and mimetics are proposed as therapeutic and diagnostic agents for obesity, diabetes and energy imbalance. | 06-04-2009 |
20110003740 | INSULIN SENSITISERS AND METHODS OF TREATMENT - The present invention relates generally to the field of therapy. The invention particularly relates to insulin sensitisers and methods of regulating glucose homeostasis and to the therapeutic or prophylactic treatment of diseases and associated conditions, in which impaired glucose uptake due to insulin resistance is involved or implicated, such as diabetes, syndrome X, hyperglycaemia, vascular disease and kidney disease. The present invention further relates to compounds and agents and compositions thereof for use in the treatment methods. | 01-06-2011 |
20110112167 | THERAPEUTIC AGENTS AND TARGETS - The present invention relates to diagnostic and therapeutic methods in relation to diabetic complications, such as blindness, nephropathy and cardiovascular disease, and inflammatory conditions, such as angina, arthritis, empyema pharyngitis and urinary tract infection. Diagnostic methods involve screening for up regulated expression of decor (Den) or thioredoxin-like protein 19 (TLP 19). Therapeutic methods involve modulation of expression or activity o Den or TLP 19. The invention also relates to screening methods for identifying functional signal sequences to screen for secreted, membrane-bound and exported proteins and cell surface receptors. | 05-12-2011 |
20140011848 | INSULIN SENSITISERS AND METHODS OF TREATMENT - The present invention relates generally to the field of therapy. The invention particularly relates to insulin sensitisers and methods of regulating glucose homeostasis and to the therapeutic or prophylactic treatment of diseases and associated conditions, in which impaired glucose uptake due to insulin resistance is involved or implicated, such as diabetes, syndrome X, hyperglycaemia, vascular disease and kidney disease. The present invention further relates to compounds and agents and compositions thereof for use in the treatment methods. | 01-09-2014 |
Patent application number | Description | Published |
20100076665 | Process for the open-and closed-loop control of an internal combustion engine with a common rail system including individual accumulators - For an internal combustion engine with a common rail system including individual accumulators, a process for open- and closed-loop control is proposed, in which the individual accumulator pressure (pE) is detected within a measuring interval and stored, an absolute minimum value of the stored individual accumulator pressure (pE) is interpreted as the end of the main injection, and on the basis of the end of the main injection, a mathematical function is used to calculate a virtual starting time for the main injection. In the measuring interval after the end of the main injection, the individual accumulator pressure (pE) is filtered within a time window, a local minimum value of the filtered individual accumulator pressure is interpreted as the end of a post-injection, and a mathematical function is used to calculate a virtual start of the post-injection. | 03-25-2010 |
20100280743 | INDIVIDUAL ACCUMULATOR, HIGH-PRESSURE COMPONENT, AND COMMON RAIL FUEL INJECTION SYSTEM, AS WELL AS AN INTERNAL COMBUSTION ENGINE, ELECTRONIC CONTROL UNIT, AND METHOD FOR THE OPEN-LOOP AND/OR CLOSED-LOOP CONTROL OF AN INTERNAL COMBUSTION ENGINE - An individual accumulator for a high-pressure component of a high-pressure fuel guide of a common rail fuel injection system. The individual accumulator is equipped with a pressure sensor, and the common rail fuel injection system is equipped with a source of high pressure and a fuel injector, which has a fluid connection with this source of high pressure via the high-pressure fuel guide, for injecting the fuel into a working chamber of an internal combustion engine. The pressure sensor is designed as a strain sensor. | 11-04-2010 |
20110130944 | METHOD FOR AUTOMATICALLY CONTROLLING AN INTERNAL COMBUSTION ENGINE - A a method for automatically controlling an internal combustion engine, in which an individual accumulator pressure (pE) of a common rail system is detected in a measurement interval and stored; in which an evaluation window is determined for the stored individual accumulation pressure (pE), within which window an injection was brought about; in which, in a first step, both a representative injection start and a trial injection end are determined in this evaluation window as a function of the detected pressure values, and, in a second step, both a trial injection start and a representative injection end are determined in this evaluation window as a function of the detected pressure values; in which the representative injection start is checked for plausibility against the trial injection start; and in which the representative injection end is checked for plausibility against the trial injection end. | 06-02-2011 |
20140209065 | COMMON-RAIL SYSTEM, INTERNAL COMBUSTION ENGINE AND DEVICE AND METHOD FOR CONTROLLING AND/OR REGULATING AN INTERNAL COMBUSTION ENGINE - Exemplary illustrations are provided of a common rail system for an internal combustion engine, having a rail for fuel and an injector for the purpose of injecting the fuel into a working space of the internal combustion engine, said injector having a fluid connection to said rail via a high-pressure conduit. The high-pressure conduit may have a high-pressure component with an individual reservoir, and the high-pressure conduit and/or the rail may have a pressure measurement device. The pressure measurement device may be coupled to a local logic and storage device of a decentralized, local electronic device which is designed for the purpose of locally analyzing and storing measurement data of the pressure measurement device, e.g., injector data and/or rail data, and the pressure measurement device is connected to the central electronic device via a bus, with the local logic and storage device connected between the same. | 07-31-2014 |
20160084210 | QUANTITY-LIMITING VALVE - In a quantity limiting valve for a fuel injection system of an internal combustion engine including a cylinder with an inflow region and an outflow region separated by a piston axially movably disposed in the cylinder and a flow limiting fluid flow path extending along the piston between the inflow and outflow regions wherein the piston is biased with its front surface into contact with a stop element, the contact area between the front surface and the stop surface includes between the piston and the stop element a contact structure providing for an intermediate space which is in communication with the inflow region thereby to expose the front surface of the piston to the pressure of the fluid in the inflow region. | 03-24-2016 |
20160138509 | DETERMINING START OF INJECTION OF AN INJECTOR OF AN INTERNAL COMBUSTION ENGINE - A method for determining a start of injection of an injector of an internal combustion engine, including the following steps: time-resolved detecting of an individual storage pressure curve in a measurement interval; determining a test injection start with the aid of the individual storage pressure curve; determining a tendency of the individual storage pressure curve in a predetermined test interval prior to the test injection start; correcting the individual storage pressure curve subject to the tendency; and determining a start of injection with the aid of the corrected individual storage pressure curve. | 05-19-2016 |