Patent application number | Description | Published |
20090139985 | Multiple stage open coil electric resistance heater with balanced coil arrangement and heater cool end termination and method of use - A multiple stage open coil electrical resistance heater uses a unique coil configuration on either side of a dividing support plate so that the air passing through the heater is heated uniformly when one or more stages of the heater are energized. The coil configuration also creates a termination zone on one side of the heater so that the terminations of the coils can be situated on the cool side of the heater. The heater coils also includes specially configured terminals to facilitate connection to power using an elongated member such as a stud or bolt. | 06-04-2009 |
20100270287 | MICA BOARD ELECTRIC RESISTANCE WIRE HEATER AND METHOD OF USE - A mica board heater has a mica board support plate assembly that isolates the mica boards from the frame of the heater. The mica board support plate assembly includes a mica board with openings sized to receive ends of the mica boards that support the resistance wires. The mica board with the specially sized openings is supported by a frame that is attached to the heater frame. By using the mica board support plate assembly, the mica boards are electrically isolated from the frame and without compromising the structural soundness of the frame. | 10-28-2010 |
20120033951 | CLOSE QUARTER ELECTRIC RESISTANCE HEATER AND METHOD OF USE - A close quarter electric resistance heater comprises a ribbon heater element that is woven between ribbon support segments and within a heater shell. The ribbon support segments form an annulus on each end of the heater and are linked to each other using connectors. The connectors space the ribbon support segments apart from each other to facilitate the weaving of the ribbon element along the inside of the heater shell for heating purposes. The connectors also link the ribbon support segments to the shell. The ribbon heater element has faces that are wider than its edges and the ribbon heater element is woven on the support segments such that the edges face the heater shell. This configuration minimizes the migration of the ribbon heater element towards the shell and possible short circuiting of the heater. | 02-09-2012 |
20120111853 | FOLDABLE ELECTRIC RESISTANCE HEATER AND METHOD OF USE - A foldable electric resistance heater comprises at least a pair of insulator plates with a resistance wire threaded through openings in the insulator plates. In one mode, the insulator plates are folded with respect to each other and fastened together using one or more fasteners. In another mode, the plates can have other angled configurations with respect to each other. One or more insulators is positioned between the folded plates or adjacent the plates to isolate the resistance wire. The folded plate configuration and resistance wire provide significant advantages in manufacturing costs while forming a more robust heater configuration. | 05-10-2012 |
20120263444 | ELECTRIC RESISTANCE HEATER ASSEMBLY AND METHOD OF USE - An electrical resistance heating assembly comprises a heater ribbon woven through a first mica board. The heater ribbon extends upwardly from a top surface of the first mica board to provide heat to a fluid passing over the upwardly extending heater ribbon. The heat ribbon on an underside of the first mica board is electrically isolated by a second mica board positioned adjacent the first mica board. The first and second mica boards are held together with by a clamp-containing metal place positioned adjacent the second mica board with the clamps bent over the first mica board to keep the mica boards together. | 10-18-2012 |
20150181652 | SILICONE BAND CABLE HEATER ASSEMBLY, METHOD OF MAKING AND METHOD OF USE - A silicone band heater assembly includes a silicone heater cable, lead wires, and a zip tie connection. The heater cable consists of a resistance heater wire that is optionally surrounded by a fiberglass braid, which in turn is encased in a silicone insulator. Each end of the heater cable includes an overmolded zip tie segment, which includes the splice connection between the lead wire and resistance wire, and the ability to link the ends of the heater cable assembly together when being clamped to a desired structure. | 06-25-2015 |
Patent application number | Description | Published |
20090270329 | METHODS OF ADMINISTERING PORCINE B-DOMAINLESS FVIII - The present invention provides a method of administering porcine B-domainless factor VIII (OBI-1) to a patient having factor VIII deficiency to provide more rapid and effective protection against bleeding episodes, compared to formerly available methods, or to provide more effective protection to such patients during non-bleeding periods. This invention is based on the discovery that the recombinant B-domainless porcine fVIII, termed OBI-1, has greater bioavailability compared to the natural porcine fVIII partially purified from porcine plasma, termed HYATE:C. Therefore, the inventive method employs lower unit doses of OBI-1, including, alternatively, omission of antibody-neutralizing dosage, or has longer intervals between the administration, compared to HYATE:C, to provide equivalent protection in patients having fVIII deficiency. The invention further provides pharmaceutical compositions and kits containing OBI-1 in combination with a pharmaceutically acceptable carrier, that are useful for treating patients in need of fVIII more effectively. | 10-29-2009 |
20090325881 | MODIFIED FACTOR VIII - Methods of treating patients with Factor VIII deficiency by administration of modified porcine factor VIII are disclosed. The particular modified porcine factor VIII is one in which most of the B domain has been removed through genetic engineering. This modified factor VIII is particularly useful for treatment of hemophiliacs, especially those undergoing bleeding episodes. | 12-31-2009 |
20110077203 | NUCLEIC ACID AND AMINO ACID SEQUENCES ENCODING HIGH-LEVEL EXPRESSOR FACTOR VIII POLYPEPTIDES AND METHODS OF USE - Methods and compositions are provided that allow for high-level expression of a factor VIII polypeptide. More specifically, methods and compositions are provided comprising nucleic acid and amino acid sequences comprising a modified factor VIII that result in high-level expression of the polypeptide. The methods and compositions of the invention find use in the treatment of factor VIII deficiency including, for example, hemophilia A. | 03-31-2011 |
20120270788 | Method of Administering Porcine B-Domainless fVIII - The present invention provides a method of administering porcine B-domainless factor VIII (OBI-1) to a patient having factor VIII deficiency to provide more rapid and effective protection against bleeding episodes, compared to formerly available methods, or to provide more effective protection to such patients during non-bleeding periods. This invention is based on the discovery that the recombinant B-domainless porcine fVIII, termed OBI-1, has greater bioavailability compared to the natural porcine fVIII partially purified from porcine plasma, termed HYATE:C. Therefore, the inventive method employs lower unit doses of OBI-1, including, alternatively, omission of antibody-neutralizing dosage, or has longer intervals between the administration, compared to HYATE:C, to provide equivalent protection in patients having fVIII deficiency. The invention further provides pharmaceutical compositions and kits containing OBI-1 in combination with a pharmaceutically acceptable carrier, that are useful for treating patients in need of fVIII more effectively. | 10-25-2012 |
20130005656 | Modified Factor VIII - Methods of treating patients with Factor VIII deficiency by administration of modified porcine factor VIII are disclosed. The particular modified porcine factor VIII is one in which most of the B domain has been removed through genetic engineering. This modified factor VIII is particularly useful for treatment of hemophiliacs, especially those undergoing bleeding episodes. | 01-03-2013 |
20140193441 | Method of Administering Porcine B-domainless fVIII - The present invention provides a method of administering porcine B-domainless factor VIII (OBI-1) to a patient having factor VIII deficiency to provide more rapid and effective protection against bleeding episodes, compared to formerly available methods, or to provide more effective protection to such patients during non-bleeding periods. This invention is based on the discovery that the recombinant B-domainless porcine fVIII, termed OBI-1, has greater bioavailability compared to the natural porcine fVIII partially purified from porcine plasma, termed HYATE:C. Therefore, the inventive method employs lower unit doses of OBI-1, including, alternatively, omission of antibody-neutralizing dosage, or has longer intervals between the administration, compared to HYATE:C, to provide equivalent protection in patients having fVIII deficiency. The invention further provides pharmaceutical compositions and kits containing OBI-1 in combination with a pharmaceutically acceptable carrier, that are useful for treating patients in need of fVIII more effectively. | 07-10-2014 |
20160030529 | TARGETED ELIMINATION OF FACTOR VIII IMMUNE CELLS - This disclosure relates to composition and methods for improving blood clotting in a subject that developed anti-factor VIII antibodies. In certain embodiments, this disclosure contemplates a conjugate comprising a toxin, e.g., ricin, abrin, saporin, coupled to factor VIII or functional variant thereof either through a linking group or as a fusion protein. | 02-04-2016 |