Patent application number | Description | Published |
20090018403 | TRACKABLE IMPLANTABLE SENSOR DEVICES, SYSTEMS, AND RELATED METHODS OF OPERATION - An implantable biocompatible sensor unit includes a sensor body of a biocompatible material configured for in vivo placement proximate a tumor treatment site. The sensor body includes at least one sensor element are configured to provide data corresponding to treatment of the tumor treatment site. The sensor body further includes a transmitter coil and associated electronic components configured for wireless transmittal of the data to a spatially remote receiver. In addition, the sensor body includes a high-atomic weight member that is configured to be detectable by an imaging modality. The sensor unit is configured to be inductively powered to wirelessly transmit the data to the remote receiver while remaining implanted proximate the tumor treatment site. Related medical systems and methods of operation are also discussed. | 01-15-2009 |
20090250602 | SINGLE-USE EXTERNAL DOSIMETERS FOR USE IN RADIATION THERAPIES - Methods, systems, devices, and computer program products include positioning single-use radiation sensor patches that have adhesive means onto the skin of a patient to evaluate the radiation dose delivered during a treatment session. The sensor patches are configured to be minimally obtrusive and operate without the use of externally extending power cords or lead wires. | 10-08-2009 |
20090275793 | BRACHYTHERAPY DEVICES AND RELATED METHODS AND COMPUTER PROGRAM PRODUCTS - Methods of forming a low-dose-rate (LDR) brachytherapy device include depositing a solution comprising a soluble form of a radioactive material on a substrate. A water-insoluble form of the radioactive material is formed on the substrate by chemical precipitation and/or thermal decomposition. | 11-05-2009 |
20100233352 | Brachytherapy Devices and Related Methods and Computer Program Products - A low-dose-rate (LDR) brachytherapy device having a spatiotemporal radiation profile includes an elongated body having a radioactive material in a spatial pattern to provide a spatial radiation profile with a radiation intensity that varies along a length of the elongated body. The radioactive material includes at least first and second radioisotopes having at least first and second respective decay profiles that together provide a temporal radiation profile that is different from the first and second decay profiles. The spatial radiation profile and the temporal radiation profile form a net spatiotemporal radiation profile configured to provide a radiotherapy plan for a patient. | 09-16-2010 |
20100298672 | METHODS FOR EVALUATING A SUBJECT USING DATA ASSOCIATED WITH A FLUORESCENT ANALYTE - Methods, systems, devices and computer program product include: (i) administering a fluorescent analyte to a subject; (ii) repetitively emitting excitation light from a sensor over a desired monitoring period; (iii) detecting fluorescence intensity in response to the excitation light using the sensor that outputs the excitation light; and (iv) using data associated with the detected fluorescence intensity to perform at least one of: (a) calculate the concentration or dose of the analyte received proximate to the sensor site; (b) evaluate the pharmacodynamic or pharmacokinetic activity of the fluorescent analyte; (c) confirm Ab attachment to a tumor site; (d) monitor a non-target site to confirm it is not unduly affected by a therapy; (e) monitor for changes in cellular properties; (f) use the calculated dose or concentration data to adjust or customize a therapeutic amount of the analyte administered to the subject; (g) confirm micelle concentration at a target site and then stimulate toxin release based on the confirmation; and (h) monitor for the expression of a protein produced from a gene therapy modification. | 11-25-2010 |
20110161012 | READERS AND COMPUTER PROGRAM PRODUCTS THAT COOPERATE WITH SINGLE-USE EXTERNAL DOSIMETERS FOR USE IN RADIATION THERAPIES - Methods, systems, devices, and computer program products include positioning single-use radiation sensor patches that have adhesive means onto the skin of a patient to evaluate the radiation dose delivered during a treatment session. The sensor patches are configured to be minimally obtrusive and operate without the use of externally extending power cords or lead wires. | 06-30-2011 |
20120316624 | SYSTEMS, DEVICES AND METHODS FOR BILATERAL CALORIC VESTIBULAR STIMULATION - An in-ear stimulation device for administering caloric stimulation to the ear canal of a subject includes (a) first and second earpieces configured to be insertable into the ear canals of the subject; (b) at least first and second thermoelectric devices thermally coupled to respective ones of the first and second earpieces; (c) a first heat sink thermally coupled to the first thermoelectric device opposite the first earpiece and a second heat sink thermally coupled to the second thermoelectric device opposite the second earpiece; and (d) a controller comprising a waveform generator in communication with the first and second thermoelectric devices, the waveform generator configured to generate a first control signal to control a first caloric output to the first thermoelectric device and a second control signal to control a second caloric output to the second caloric device. | 12-13-2012 |
20120316625 | SYSTEMS, DEVICES AND METHODS FOR CALORIC VESTIBULAR STIMULATION HAVING AN IMPEDANCE MONITOR AND/OR TEMPERATURE SENSOR - An in-ear stimulation device for administering caloric stimulation to the ear canal of a subject includes (a) first and second earpieces configured to be insertable into the ear canals of the subject; (b) at least first and second thermoelectric devices thermally coupled to respective ones of the first and second earpieces; (c) a first heat sink thermally coupled to the first thermoelectric device opposite the first earpiece and a second heat sink thermally coupled to the second thermoelectric device opposite the second earpiece; and (d) a controller comprising a waveform generator in communication with the first and second thermoelectric devices, the waveform generator configured to generate a first control signal to control a first caloric output to the first thermoelectric device and a second control signal to control a second caloric output to the second caloric device. | 12-13-2012 |
20130096360 | Brachytherapy Devices and Related Methods Providing Bioaborbability and/or Asymmetric Irradition - Methods of forming a low-dose-rate (LDR) brachytherapy device include depositing a solution comprising a soluble form of a radioactive material on a substrate. A water-insoluble form of the radioactive material is formed on the substrate by chemical precipitation and/or thermal decomposition. | 04-18-2013 |
20130296987 | Systems, Methods and Apparatus for Delivering Nerve Stimulation to a Patient with Physician Oversight - The present invention provides devices, systems and methods for delivering one or more thermal waveforms to the vestibular system and/or the nervous system of a patient. In some embodiments, the present invention provides a vestibular stimulation device configured both to generate a prescription for delivering one or more thermal waveforms and to deliver the prescribed thermal waveforms. | 11-07-2013 |
20130310907 | APPARATUS AND METHODS FOR TITRATING CALORIC VESTIBULAR STIMULATION - A device for delivering caloric vestibular stimulation to an individual, includes: (a) an earpiece configured to be at least partially insertable into the ear canal of the individual for delivering a first thermal stimulus; (b) an input unit for receiving a user input indicating efficacy of said first thermal stimulus, and (c) a controller operatively associated with said earpiece and said input unit for: (i) controlling said earpiece to provide said first thermal stimulus, and (ii) receiving a signal corresponding to the user input and generating a control signal to control the earpiece and delivering a subsequent thermal stimulus different from said first thermal stimulus. In some embodiments, each thermal stimulus is an actively controlled time varying waveform stimulus. | 11-21-2013 |
20130317576 | APPARATUS AND METHODS FOR PRODUCING BRAIN ACTIVATION VIA THE VESTIBULAR SYSTEM WITH TIME-VARYING WAVEFORMS - A device for delivering caloric vestibular stimulation to an individual, includes: (a) an earpiece configured to be at least partially insertable into the ear canal of the individual for delivering said caloric vestibular stimulation; (b) a power supply operatively associated with said earpiece; and (c) a controller operatively associated with said power supply and said earpiece for configuring said caloric vestibular stimulation as at least a first and second time-varying waveform. Preferably, the waveforms are actively controlled waveforms. | 11-28-2013 |
20140243941 | Systems, Methods and apparatus for Bilateral Caloric Vestibular Stimulation - An in-ear stimulation device for administering caloric stimulation to the ear canal of a subject includes (a) first and second earpieces configured to be insertable into the ear canals of the subject; (b) at least first and second thermoelectric devices thermally coupled to respective ones of the first and second earpieces; (c) a first heat sink thermally coupled to the first thermoelectric device opposite the first earpiece and a second heat sink thermally coupled to the second thermoelectric device opposite the second earpiece; and (d) a controller comprising a waveform generator in communication with the first and second thermoelectric devices, the waveform generator configured to generate a first control signal to control a first caloric output to the first thermoelectric device and a second control signal to control a second caloric output to the second caloric device. | 08-28-2014 |
Patent application number | Description | Published |
20080228049 | Systems, Circuits and Apparatus For In Vivo Detection of Biomolecule Concentrations Using Fluorescent Tags - Systems are disclosed wherein labeled binding molecules can be provided in vivo to tissue having biomolecules that specifically bind the labeled binding molecule. A first optical radiation is emitted into the tissue in vivo to excite the labeled binding molecule bound to the biomolecule in vivo. A second optical radiation that is emitted by the excited labeled binding molecule, in response to the excitation thereof, can be detected in vivo. Related telemetric-circuits and apparatus are also disclosed. | 09-18-2008 |
20090121144 | READERS THAT COOPERATE WITH SINGLE-USE INTERNAL DOSIMETERS FOR DETECTING RADIATION IN MEDICAL PROCEDURES/THERAPIES - Methods, systems, devices, and computer program products include positioning single-use radiation internal dosimeters with MOSFETs into a patient to evaluate the radiation dose delivered during a medical procedure or treatment session. The MOSFETs can be unpowered during irradiation. | 05-14-2009 |
20110121188 | SINGLE-USE INTERNAL DOSIMETERS FOR DETECTING RADIATION IN MEDICAL PROCEDURES/THERAPIES - Methods, systems, devices, and computer program products include positioning single-use radiation internal dosimeters with MOSFETs into a patient to evaluate the radiation dose delivered during a medical procedure or treatment session. The MOSFETs can be unpowered during irradiation. | 05-26-2011 |
20110210258 | DISPOSABLE SINGLE-USE EXTERNAL DOSIMETERS FOR DETECTING RADIATION IN FLUOROSCOPY AND OTHER MEDICAL PROCEDURES/THERAPIES - Methods, systems, devices, and computer program products include positioning single-use radiation sensor patches that have adhesive onto the skin of a patient to evaluate the radiation dose delivered during a medical procedure or treatment session. The sensor patches are configured to be relatively unobtrusive and operate during radiation without the use of externally extending power cords or lead wires. | 09-01-2011 |
20110237909 | Systems, Circuits and Apparatus For In Vivo Detection of Biomolecule Concentrations Using Fluorescent Tags - Systems are disclosed wherein labeled binding molecules can be provided in vivo to tissue having biomolecules that specifically bind the labeled binding molecule. A first optical radiation is emitted into the tissue in vivo to excite the labeled binding molecule bound to the biomolecule in vivo. A second optical radiation that is emitted by the excited labeled binding molecule, in response to the excitation thereof, can be detected in vivo. Related telemetric-circuits and apparatus are also disclosed. | 09-29-2011 |