Patent application number | Description | Published |
20080199450 | ACID CERAMIDASE AND CELL SURVIVAL - The present invention relates to methods of promoting the survival of cells by treating the cells with acid ceramidase. A kit for promoting ex vivo cell survival is also disclosed, as is a method of predicting in vitro fertilization outcome of a female subject. | 08-21-2008 |
20110052559 | DOSE ESCALATION ENZYME REPLACEMENT THERAPY FOR TREATING ACID SPHINGOMYELINASE DEFICIENCY - The invention relates to dose escalation enzyme replacement therapy using acid sphingomyelinase (ASM) for the treatment of human subjects having acid sphingomyelinase deficiency (ASMD), and, in particular, patients with non-neurological manifestations of Niemann-Pick Disease (NPD), and in certain embodiments, NPD type B. | 03-03-2011 |
20120115158 | METHOD TO DETERMINE EMBRYO AND OOCYTE QUALITY BASED ON CERAMIDASE - The present invention relates to a method of predicting the likelihood of embryo or oocyte survival. This method involves providing a sample of an embryo, an oocyte, or surrounding liquid or cells, and screening the sample for ceramidase expression or activity. The ceramidase expression or activity obtained through said screening is then correlated to a prediction of the likelihood of embryo or oocyte survival. Also disclosed is a kit. | 05-10-2012 |
20130078230 | DOSE ESCALATION ENZYME REPLACEMENT THERAPY FOR TREATING ACID SPHINOGMYELINASE DEFICIENCY - The invention relates to dose escalation enzyme replacement therapy using acid sphingomyelinase (ASM) for the treatment of human subjects having acid sphingomyelinase deficiency (ASMD), and, in particular, patients with non-neurological manifestations of Niemann-Pick Disease (NPD), and in certain embodiments, NPD type B. | 03-28-2013 |
20130078231 | DOSE ESCALATION ENZYME REPLACEMENT THERAPY FOR TREATING ACID SPHINOGMYELINASE DEFICIENCY - The invention relates to dose escalation enzyme replacement therapy using acid sphingomyelinase (ASM) for the treatment of human subjects having acid sphingomyelinase deficiency (ASMD), and, in particular, patients with non-neurological manifestations of Niemann-Pick Disease (NPD), and in certain embodiments, NPD type B. | 03-28-2013 |
20130280717 | METHOD TO DETERMINE EMBRYO AND OOCYTE QUALITY BASED ON CERAMIDASE - The present invention relates to a method of predicting the likelihood of embryo or oocyte survival. This method involves providing a sample of an embryo, an oocyte, or surrounding liquid or cells, and screening the sample for ceramidase expression or activity. The ceramidase expression or activity obtained through said screening is then correlated to a prediction of the likelihood of embryo or oocyte survival. Also disclosed is a kit. | 10-24-2013 |
20140205584 | ANTI-TNF-ALPHA THERAPY FOR THE MUCOPOLYSACCHARIDOSES AND OTHER LYSOSOMAL DISORDERS - The present invention relates to methods of treating a subject with a lysosomal disorder, by administering an agent for enzyme replacement therapy and an agent for anti-TNF-α therapy; by administering a pentosan polysulfate therapy; or by administering a substrate reduction therapy and an anti-TNF-α therapy. The invention further relates to a method of reducing inflammatory cytokines in a subject with a lysosomal disorder that is being treated by enzyme replacement therapy, by administering an agent for anti-TNF-α therapy. | 07-24-2014 |
20140287015 | CERAMIDASE AND CELL DIFFERENTIATION - The present invention relates to methods of producing chondrocytes, improving the phenotype of a chondrocyte population, promoting chondrogenesis, maintaining a cell population in a differentiated state or increasing the number of cells of a population in a differentiated state, producing a population of differentiated cells, and treating certain diseases or disorders. Each of these methods involves treating a cell population with, and/or culturing a cell population in, a ceramidase | 09-25-2014 |
20140335070 | DOSE ESCALATION ENZYME REPLACEMENT THERAPY FOR TREATING ACID SPHINGOMYELINASE DEFICIENCY - The invention relates to dose escalation enzyme replacement therapy using acid sphingomyelinase (ASM) for the treatment of human subjects having acid sphingomyelinase deficiency (ASMD), and, in particular, patients with non-neurological manifestations of Niemann-Pick Disease (NPD), and in certain embodiments, NPD type B. | 11-13-2014 |
Patent application number | Description | Published |
20090089562 | Methods and apparatuses for reducing power consumption of processor switch operations - Methods and apparatuses for reducing power consumption of processor switch operations are disclosed. One or more embodiments may comprise specifying a subset of registers or state storage elements to be involved in a register or state storage operation, performing the register or state storage operation, and performing a switch operation. The embodiments may minimize the number of registers or state storage elements involved with the standby operation by specifying only the subset of registers or state storage elements, which may involve considerably fewer than the total number of registers or state storage or elements of the processor. The switch operation may be switch from one mode to another, such as a transition to or from a sleep mode, a context switch, or the execution of various types of instructions. | 04-02-2009 |
20110072234 | Providing Hardware Support For Shared Virtual Memory Between Local And Remote Physical Memory - In one embodiment, the present invention includes a memory management unit (MMU) having entries to store virtual address to physical address translations, where each entry includes a location indicator to indicate whether a memory location for the corresponding entry is present in a local or remote memory. In this way, a common virtual memory space can be shared between the two memories, which may be separated by one or more non-coherent links. Other embodiments are described and claimed. | 03-24-2011 |
20140208042 | PROVIDING HARDWARE SUPPORT FOR SHARED VIRTUAL MEMORY BETWEEN LOCAL AND REMOTE PHYSICAL MEMORY - In one embodiment, the present invention includes a memory management unit (MMU) having entries to store virtual address to physical address translations, where each entry includes a location indicator to indicate whether a memory location for the corresponding entry is present in a local or remote memory. In this way, a common virtual memory space can be shared between the two memories, which may be separated by one or more non-coherent links. Other embodiments are described and claimed. | 07-24-2014 |
20140258757 | Methods And Apparatuses For Reducing Power Consumption Of Processor Switch Operations - Methods and apparatuses for reducing power consumption of processor switch operations are disclosed. One or more embodiments may comprise specifying a subset of registers or state storage elements to be involved in a register or state storage operation, performing the register or state storage operation, and performing a switch operation. The embodiments may minimize the number of registers or state storage elements involved with the standby operation by specifying only the subset of registers or state storage elements, which may involve considerably fewer than the total number of registers or state storage or elements of the processor. The switch operation may be switch from one mode to another, such as a transition to or from a sleep mode, a context switch, or the execution of various types of instructions. | 09-11-2014 |
Patent application number | Description | Published |
20100084531 | Beverage holder device - An attachment (A) coupled to a belt clip (B) including a rigid beverage holder frame, and a catch and catch release belt or appliance clip device. The beverage holder comprising a free swinging, rigid, cylindrical frame to perpendicularly harbor a beverage container (C) contained within or not an insulated drink container sleeve (E) attaching to belt clip device (B), providing the wearer convenient mobile storage while minimizing tipping spills and further providing the user freedom of either or both hands for other activities or tasks. | 04-08-2010 |
20100199835 | Vehicle gun stabilization platform device - A weapon stabilization platform assembly employing the action of the devices' telescoping tubular horizontal width adjustment attaching to the vertical roll over posts of a recreational off road 4×4, off road UTV, or other utility vehicle or frame vehicle by the nut and bolt compression of two bracket couplings or other attaching appliances fixed at the opposing end of each of the telescoping tubes. In a preferred embodiment, the device comprises a plurality of telescoping tubes being an outer sleeve and an inner sleeve that is sized to permit it to move horizontally in telescopic relationship to the outer sleeve, both sleeves being harbored within an anti-vibration foam cushion, being then sheathed within a protective fabric sleeve. Each tube end connecting by nut and bolt compression to axial end bracket couplings, and the bracket couplings becoming then fixed to the vertical roll over posts of a UTV or other frame by nut and bolt horizontal end compression or other locking attachment device, allowing the military, civilian, or handicapped user a vibration eliminating or reducing horizontal weapon aiming and shooting, camera or other device rest. | 08-12-2010 |