Moussa, US
Adel Moussa, Burlington, MA US
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20150224085 | METHOD OF ADMINISTERING A 5,5-FUSED HETEROARYLENE HEPATITIS C VIRUS INHIBITOR FOR TREATING OF PREVENTING HEPATITIS C VIRUS INFECTION - Provided herein are methods of administering a 5,5-fused heteroarylene hepatitis C virus inhibitor compound or an isotopic variant thereof, or a pharmaceutically acceptable salt or solvate thereof; for treating or preventing hepatitis C virus infection in a subject. | 08-13-2015 |
Adel M. Moussa, Burlington, MA US
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20080213217 | Enantiomerically pure phosphoindoles as HIV inhibitors - 3-phosphoindole compounds substantially in the form of a single enantiomer useful for the treatment of Flaviviridae virus infections, and particularly for HIV infections are provided. Also provided are pharmaceutical compositions comprising the 3-phosphoindole compounds alone or in combination with one or more other anti-viral agents, processes for their preparation, and methods of manufacturing a medicament incorporating these compounds. | 09-04-2008 |
20110039803 | SOLID FORMS OF AN ANTI-HIV PHOSPHOINDOLE COMPOUND - Solid forms comprising a compound useful in the treatment, prevention and management of various conditions and diseases are provided herein. In particular, provided herein are solid forms comprising (2-carbamoyl-5-chloro-1H-indol-3-yl)-[3-((E)-2-cyano-vinyl)-5-methyl-phenyl]-(R)-phosphinic acid methyl ester, including salts thereof, having utility for the treatment, prevention and management of conditions and disorders including, but not limited to, human immunodeficiency virus infection. | 02-17-2011 |
20110257129 | ENANTIOMERICALLY PURE PHOSPHOINDOLES AS HIV INHIBITORS - 3-phosphoindole compounds substantially in the form of a single enantiomer useful for the treatment of Flaviviridae virus infections, and particularly for HIV infections are provided. Also provided are pharmaceutical compositions comprising the 3-phosphoindole compounds alone or in combination with one or more other anti-viral agents, processes for their preparation, and methods of manufacturing a medicament incorporating these compounds. | 10-20-2011 |
20130217644 | Pharmaceutical Compositions of 2'-C-Methyl-Guanosine, 5'-[2[(3-Hydroxy-2,2-Dimethyl-1-Oxopropyl)Thio]Ethyl N-(Phenylmethyl)Phosphoramidate] - Provided herein are pharmaceutical compositions, and in particular, oral pharmaceutical compositions, and methods of using these pharmaceutical compositions in the treatment of viral infections, including hepatitis C virus infections in hosts in need thereof. In certain embodiments, pharmaceutical compositions of 2′-C-methyl-guanosine, 5′-[2-[(3-hydroxy-2,2-dimethyl-1-oxopropyl)thio]ethyl N-(phenylmethyl)phosphoramidate] are provided which display remarkable efficacy and bioavailability for the treatment of, for example, HCV infection in a human. | 08-22-2013 |
20130315866 | 3',5'-CYCLIC PHOSPHORAMIDATE PRODRUGS FOR HCV INFECTION - Provided herein are compounds, compositions and methods for the treatment of Flaviviridae infections, including HCV infections. In certain embodiments, compounds and compositions of nucleoside derivatives are disclosed, which can be administered either alone or in combination with other anti-viral agents. | 11-28-2013 |
20130315868 | D-AMINO ACID COMPOUNDS FOR LIVER DISEASE - Provided herein are compounds, compositions and methods for the treatment of liver disease and conditions, including HCV infections. In certain embodiments, compounds and compositions of nucleoside derivatives are disclosed, which can be administered either alone or in combination with other anti-viral agents. | 11-28-2013 |
20140086873 | Esters and Malonates of SATE Prodrugs - Provided herein are compounds, compositions and methods for the treatment of Flaviviridae infections, including HCV infections. In certain embodiments, compounds and compositions of nucleoside derivatives are disclosed, which can be administered either alone or in combination with other anti-viral agents. In certain embodiments, provided herein are compounds according to Formula 1001: | 03-27-2014 |
20140099283 | 2'-CHLORO NUCLEOSIDE ANALOGS FOR HCV INFECTION - Provided herein are compounds, compositions and methods for the treatment of Flaviviridae infections, including HCV infections. In certain embodiments, compounds and compositions of nucleoside derivatives are disclosed, which can be administered either alone or in combination with other anti-viral agents. In certain embodiments, the compounds are 2′-chloro nucleosides according to Formula 2001: | 04-10-2014 |
20140112886 | DINUCLEOTIDE COMPOUNDS FOR HCV INFECTION - Provided herein are compounds, compositions and methods for the treatment of Flaviviridae infections, including HCV infections. In certain embodiments, compounds and compositions of nucleoside derivatives are disclosed, which can be administered either alone or in combination with other anti-viral agents. In certain embodiments, the compounds comprise two 2′-methyl nucleotides linked according to Formula I: | 04-24-2014 |
20140112887 | 2',4'-BRIDGED NUCLEOSIDES FOR HCV INFECTION - Provided herein are compounds, compositions and methods for the treatment of Flaviviridae infections, including HCV infections. In certain embodiments, compounds and compositions of nucleoside derivatives are disclosed, which can be administered either alone or in combination with other anti-viral agents. In certain embodiments, the compounds are 2′,4′-bridged nucleosides which display remarkable efficacy and bioavailability for the treatment of, for example, HCV infection in a human. In certain embodiments, the 2′,4′-bridged nucleosides are of Formula 3001: | 04-24-2014 |
20140140951 | D-Alanine Ester of Rp-Nucleoside Analog - Provided herein are compounds, compositions and methods for the treatment of Flaviviridae infections, including HCV infections. In certain embodiments, compounds and compositions of nucleoside derivatives are disclosed, which can be administered either alone or in combination with other anti-viral agents. In certain embodiments, provided herein is an isolated compound according to Formula Ia: | 05-22-2014 |
20140140952 | D-Alanine Ester of Sp-Nucleoside Analog - Provided herein are compounds, compositions and methods for the treatment of Flaviviridae infections, including HCV infections. In certain embodiments, compounds and compositions of nucleoside derivatives are disclosed, which can be administered either alone or in combination with other anti-viral agents. In certain embodiments, provided herein is an isolated compound according to Formula Ib: | 05-22-2014 |
20140178338 | 4'-FLUORO NUCLOSIDES FOR THE TREATMENT OF HCV - Provided herein are compounds, compositions and methods for the treatment of Flaviviridae infections, including HCV infections. In certain embodiments, compounds and compositions of nucleoside derivatives are disclosed, which can be administered either alone or in combination with other anti-viral agents. In certain embodiments, the compounds are according to Formula 1501: | 06-26-2014 |
20140248241 | 3'-DEOXY NUCLEOSIDES FOR THE TREATMENT OF HCV - Provided herein are compounds, compositions and methods for the treatment of Flaviviridae infections, including HCV infections. In certain embodiments, compounds and compositions of nucleoside derivatives are disclosed, which can be administered either alone or in combination with other anti-viral agents. In certain embodiments, the compounds are 3′-deoxy nucleoside compounds according to Formula 3001a or 3001b: | 09-04-2014 |
20140248242 | THIOPHOSPHATE NUCLEOSIDES FOR THE TREATMENT OF HCV - Provided herein are compounds, compositions and methods for the treatment of Flaviviridae infections, including HCV infections. In certain embodiments, the compounds are according to Formula 2001: | 09-04-2014 |
20140294769 | 2',4'-FLUORO NUCLEOSIDES FOR THE TREATMENT OF HCV - Provided herein are compounds, methods and pharmaceutical compositions for use in treatment of viral infections, including hepatitis C virus (HCV) infections, in hosts in need thereof. In certain embodiments, the compounds are 2′,4′-fluoro nucleosides according to Formula 1001: | 10-02-2014 |
20150037282 | D-AMINO ACID PHOSPHORAMIDATE PRONUCLEOTIDES OF HALOGENO PYRIMIDINE COMPOUNDS FOR LIVER DISEASE - Provided herein are compounds, compositions, and methods for the treatment of viral infections, for example, Flaviviridae infections, including HCV infections. In certain embodiments, compounds and compositions of nucleoside derivatives are disclosed, which can be administered either alone or in combination with other anti-viral agents. In certain embodiments, the compounds are D-amino acid phosphoramidate halogeno pyrimidine nucleoside analog compounds which display remarkable efficacy and bioavailability for the treatment of, for example, HCV infection in a human. In certain embodiments, the compounds are of Formula I: | 02-05-2015 |
Alaa-Addin Moussa, Carlsbad, CA US
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20140266883 | ENERGY CONSERVATION APPARATUS FOR GEOFENCE APPLICATIONS - Methods, systems and devices are provided for operating a GPS engine in an active geofence monitoring state for no more than a first QoS period to obtain a first GPS fix. The GPS engine may also be set to operate in the active geofence monitoring state for no more than a second lower QoS period to obtain a second GPS fix in response to determining the first GPS fix was not obtained. The method may determine whether a geofence breach is detected in response to determining the GPS engine obtained the first GPS fix. The GPS engine may be set to operate in the active geofence monitoring state for no more than the second QoS period to obtain the second GPS fix in response to determining the geofence breach is not detected. The GPS engine may thus operate in the active geofence monitoring state to obtain the second GPS fix. | 09-18-2014 |
Alaa-Addin Moussa, Oceanside, CA US
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20100002629 | System and Method for Mobility Restriction in Wireless Communications Systems - A system and method for mobility restriction in wireless communications systems is provided. A method for base station operations includes receiving a request for service from a terminal, sending a request for authorization of the terminal to a controller, receiving in response to the request for authorization, an indication that the terminal is authorized, and granting access to the terminal. The indication includes a mobility restriction classification associated with the terminal. | 01-07-2010 |
20100014461 | System and Method for Creating Multiple Mobility Profiles per Subscriber in Wireless Communications Systems - A system and method for creating multiple mobility profiles per subscriber in wireless communications systems is provided. A method includes receiving a request for service from a terminal, sending a request for authorization of the terminal to a server, receiving, in response to the request for authorization, an indication that the terminal is authorized, and granting access to the terminal. The indication includes a mobility classification associated with the terminal. The mobility classification is based on the terminal's operating conditions. | 01-21-2010 |
Alma Cardenas Moussa, Dublin, CA US
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20120280543 | MULTIFUNCTIONAL BLANKET AND COVERING DEVICE - The present invention relates to multifunctional blanket for covering a standard rear facing infant carrier, a baby, a stroller, a child seating device, a nursing woman, and other child carriers. The multifunctional blanket comprising (a) a reversible outer cover, in which the outer cover has opposite sides of equal length, a top portion, and a bottom portion, wherein the top and bottom portions have the same width; (b) a reversible inner cover, the inner cover having opposite sides of equal length, a top portion, and a bottom portion, wherein the top and bottom portions have the same width; and (c) a set of edge-fastening device attached to each opposite sides of the cover. | 11-08-2012 |
Charbel Moussa, Germantown, MD US
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20140271668 | INCREASING PARKIN ACTIVITY BY ADMINISTERING A DEUBIQUITINATING ENZYME INHIBITOR - Provided herein are methods of promoting parkin activity in a subject, comprising: selecting a subject with a disorder associated with decreased Parkin activity; and administering to the subject an effective amount of a composition that increases parkin activity, wherein the composition is an inhibitor of a deubiquitinating enzyme. | 09-18-2014 |
20150087653 | TREATING NEURAL DISEASE WITH TYROSINE KINASE INHIBITORS - Provided herein are methods of treating or preventing a neurodegenerative disease, a myodegenerative disease or a prion disease in a subject comprising administering a tyrosine kinase inhibitor. | 03-26-2015 |
Feras Moussa, Houston, TX US
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20100080493 | ASSOCIATING OPTICAL CHARACTER RECOGNITION TEXT DATA WITH SOURCE IMAGES - A system and method for associating optical character recognition text data with source images are provided. In one embodiment, an association module of a computing system is configured to receive text data from an OCR engine; associate the text data with a source image; and output associated optical character recognition data including the source image, the text data associated with the source image, and a plurality of referrers. Each referrer of the plurality of referrers may indicate a different image reference. The plurality of referrers are configured to cause the viewer application to output the text data associated with the source image to each instance of the source image that is rendered as part of the fixed-layout document in accordance with the multiple image references. | 04-01-2010 |
George Moussa, Sunnyvale, CA US
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20090070513 | Method and Apparatus for Distributed Direct Memory Access for Systems on Chip - A distributed direct memory access (DMA) method, apparatus, and system is provided within a system on chip (SOC). DMA controller units are distributed to various functional modules desiring direct memory access. The functional modules interface to a systems bus over which the direct memory access occurs. A global buffer memory, to which the direct memory access is desired, is coupled to the system bus. Bus arbitrators are utilized to arbitrate which functional modules have access to the system bus to perform the direct memory access. Once a functional module is selected by the bus arbitrator to have access to the system bus, it can establish a DMA routine with the global buffer memory. | 03-12-2009 |
20110320672 | METHOD AND APPARATUS FOR DISTRIBUTED DIRECT MEMORY ACCESS FOR SYSTEMS ON CHIP - A distributed direct memory access (DMA) method, apparatus, and system is provided within a system on chip (SOC). DMA controller units are distributed to various functional modules desiring direct memory access. The functional modules interface to a systems bus over which the direct memory access occurs. A global buffer memory, to which the direct memory access is desired, is coupled to the system bus. Bus arbitrators are utilized to arbitrate which functional modules have access to the system bus to perform the direct memory access. Once a functional module is selected by the bus arbitrator to have access to the system bus, it can establish a DMA routine with the global buffer memory. | 12-29-2011 |
20130138877 | METHOD AND APPARATUS FOR DISTRIBUTED DIRECT MEMORY ACCESS FOR SYSTEMS ON CHIP - A distributed direct memory access (DMA) method, apparatus, and system is provided within a system on chip (SOC). DMA controller units are distributed to various functional modules desiring direct memory access. The functional modules interface to a systems bus over which the direct memory access occurs. A global buffer memory, to which the direct memory access is desired, is coupled to the system bus. Bus arbitrators are utilized to arbitrate which functional modules have access to the system bus to perform the direct memory access. Once a functional module is selected by the bus arbitrator to have access to the system bus, it can establish a DMA routine with the global buffer memory. | 05-30-2013 |
George Moussa, Dublin, CA US
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20120079181 | TRANSLATING MEMORY MODULES FOR MAIN MEMORY - A translating memory module is disclosed including a printed circuit board, at least one memory integrated circuit coupled to the printed board, and at least one support chip coupled to the printed circuit board and coupled between the edge connector and the at least one memory integrated circuit. The at least one support chip includes a bi-directional translator to translate between a first memory communication protocol for the at least one memory integrated circuit and a second memory communication protocol for a memory channel differing from the first memory communication protocol. The second memory communication protocol to communicate data, address, and control signals over the memory channel bus to read and write data into the memory of the translating memory module. | 03-29-2012 |
20130138874 | SYSTEMS WITH PROGRAMMABLE HETEROGENEOUS MEMORY CONTROLLERS FOR MAIN MEMORY - A translating memory module is disclosed including a printed circuit board, at least one memory integrated circuit coupled to the printed board, and at least one support chip coupled to the printed circuit board and coupled between the edge connector and the at least one memory integrated circuit. The at least one support chip includes a bi-directional translator to translate between a first memory communication protocol for the at least one memory integrated circuit and a second memory communication protocol for a memory channel differing from the first memory communication protocol. The second memory communication protocol to communicate data, address, and control signals over the memory channel bus to read and write data into the memory of the translating memory module. | 05-30-2013 |
20140075106 | METHODS OF COMMUNICATING TO DIFFERENT TYPES OF MEMORY MODULES IN A MEMORY CHANNEL - A computer system is disclosed including a printed circuit board (PCB) including a plurality of traces, at least one processor mounted to the PCB to couple to some of the plurality of traces, a heterogeneous memory channel including a plurality of sockets coupled to a memory channel bus of the PCB, and a memory controller coupled between the at least one processor and the heterogeneous memory channel. The heterogeneous memory channel includes a plurality of sockets coupled to a memory channel bus of the PCB. The plurality of sockets are configured to receive a plurality of different types of memory modules. The memory controller may be a programmable heterogeneous memory controller to flexibly adapt to the memory channel bus to control access to each of the different types of memory modules in the heterogeneous memory channel. | 03-13-2014 |
Georges Moussa, Alpharetta, GA US
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20110254655 | System & Method For Driver Training In A Controlled Driving Environment - A method and system for monitoring and controlling driver performance in a controlled driving environment. A portable information device is provided to a driver who registers with a server computer for controlling vehicle operation in the driving environment. A record for the driver is stored in a database associated with the server computer. A vehicle is activated using the portable information device for at least an amount of time exceeding a preset threshold value. A speed level and a safety level for the vehicle are dynamically set based on the driver's performance in the driving environment. The driver's performance is monitored in the controlled driving environment and each driving violation that occurs is determined. Violation points are assigned to the driver based on each driving violation and the violation points are added to the driver record stored in the database. The speed level is set to a value less than a threshold speed level if the violation points stored for the driver exceeds a threshold for violation points. | 10-20-2011 |
Hachem Moussa, Plano, TX US
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20090122802 | Enhanced encapsulation mechanism using GRE protocol - Wireless gateway nodes are enabled to support mobile node services, such as content based billing, when a data treatment server is present in the system. Using one of a defined Content Flow Label (CFL), an Application Program Interface (API), and a compression protocol header, content based billing is provided such as by exchanging content and byte count information with the data treatment server. | 05-14-2009 |
20100220627 | Enhanced Encapsulation Mechanism using GRE Protocol - Wireless gateway nodes are enabled to support mobile node services, such as content based billing, when a data treatment server is present in the system. Using one of a defined Content Flow Label (CFL), an Application Program Interface (API), and a compression protocol header, content based billing is provided such as by exchanging content and byte count information with the data treatment server. | 09-02-2010 |
20120300705 | Enhanced Encapsulation Mechanism Using GRE Protocol - Wireless gateway nodes are enabled to support mobile node services, such as content based billing, when a data treatment server is present in the system. Using one of a defined Content Flow Label (CFL), an Application Program Interface (API), and a compression protocol header, content based billing is provided such as by exchanging content and byte count information with the data treatment server. | 11-29-2012 |
20130235802 | Enhanced Encapsulation Mechanism Using GRE Protocol - Wireless gateway nodes are enabled to support mobile node services, such as content based billing, when a data treatment server is present in the system. Using one of a defined Content Flow Label (CFL), an Application Program Interface (API), and a compression protocol header, content based billing is provided such as by exchanging content and byte count information with the data treatment server. | 09-12-2013 |
Khalil Moussa, Charlotte, NC US
Patent application number | Description | Published |
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20090267269 | Selective Deposition Modeling Using CW UV LED Curing - A continuous-wave (CW) ultraviolet (UV) curing system for solid freeform fabrication (SFF) is provided, wherein the curing system is configured to provide an exposure of UV radiation for one or more layers of UV-curable material. One or more UV exposures may initiate curing of a curable material in the layer dispensed by a solid freeform fabrication apparatus. One approach to provide the single or multiple UV exposures is the use of one or more UV LEDs, which generate UV radiation without generating any substantial amounts of infrared (IR) radiation at the same time. This allows for the curing process to be energy efficient and also allows for the SFF system to be far less complex. | 10-29-2009 |
20090283109 | Methods for Cleaning and Curing Solid Freeform Fabrication Parts - A post-processing system is provided for cleaning and/or curing a part produced by solid freeform fabrication (SFF). The post-processing systems include a housing, a part retaining device to retain the part within the housing, and an actinic radiation source to cure the part with actinic radiation. The systems also include a fluid circulation device adapted to expose the part to cleaning fluid and/or to allow the cleaning fluid to absorb actinic radiation to permit filtration of removed build material to allow extended use of the cleaning fluid. Certain systems include a first rotating portion that can rotate the retained part about a first axis, and further systems include a second rotating portion that can rotate the retained part about a second axis. The systems also include additional features to provide safe and efficient cleaning and/or curing of parts produced by SFF. | 11-19-2009 |
20090283119 | Post-Processing System For Solid Freeform Fabrication Parts - A post-processing system is provided for cleaning and/or curing a part produced by solid freeform fabrication (SFF). The post-processing systems include a housing, a part retaining device to retain the part within the housing, and an actinic radiation source to cure the part with actinic radiation. The systems also include a fluid circulation device adapted to expose the part to cleaning fluid and/or to allow the cleaning fluid to absorb actinic radiation to permit filtration of removed build material to allow extended use of the cleaning fluid. Certain systems include a first rotating portion that can rotate the retained part about a first axis, and further systems include a second rotating portion that can rotate the retained part about a second axis. The systems also include additional features to provide safe and efficient cleaning and/or curing of parts produced by SFF. | 11-19-2009 |
20110304074 | Selective Deposition Modeling Methods for Improved Support-Object Interface - There are provided method and apparatus for the forming of three-dimensional objects in a layered fashion, wherein improvements are made to the support structure to improve the quality of the resulting three-dimensional objects. The support structure may include encapsulation along the interface boundary of the support-object interface to prevent or reduce the likelihood of separation of the build material, that forms the three-dimensional object, from the support material, that forms the support structure, or vice versa. The support structure may also or alternatively include both a porous support structure and a solid support structure to prevent or reduce the likelihood of, separation of the support structure from the build platform and to improve the quality of the down-facing surfaces of the three-dimensional object. Methods are also provided for selectively depositing the support material and build material and for encapsulating the interface boundary with support material. | 12-15-2011 |
Khalil Moussa, Chapel Hill, NC US
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20120133080 | Additive Manufacturing Methods for Improved Curl Control and Sidewall Quality - There is provided methods and apparatus for improving the accuracy of three-dimensional objects formed by additive manufacturing. By depositing or hardening build material within the interior of the layers in certain patterns, the stresses that lead to curl in the object can be isolated and controlled. Similarly, certain patterns for depositing or hardening the build material provide for reduced layer thicknesses to improve the sidewall quality of the object being formed. The patterns within the interior of the layers can include gaps or voids for particular layers being deposited or hardened, and the gaps or voids can be partially filled, fully filled, or not filled at all when subsequent layers are deposited or hardened. Accordingly, the accuracy of three-dimensional objects formed by additive manufacturing is improved. | 05-31-2012 |
20120213976 | Support Material and Applications Thereof - In one aspect, support materials operable for use in 3D printing systems are described herein. In some embodiments, a support material comprises a wax component comprising at least one ethoxylated fatty alcohol and a viscosity modifying agent, wherein the support material is water dispersible. In some embodiments, the wax component comprises a mixture of at least one fatty alcohol and at least one ethoxylated fatty alcohol. | 08-23-2012 |
20130236706 | Support Material and Applications Thereof - In one aspect, support materials operable for use in 3D printing systems are described herein. In some embodiments, a support material comprises a wax component comprising at least one ethoxylated fatty alcohol and a viscosity modifying agent, wherein the support material is water dispersible. In some embodiments, the wax component comprises a mixture of at least one fatty alcohol and at least one ethoxylated fatty alcohol. | 09-12-2013 |
20140275317 | THREE DIMENSIONAL PRINTING MATERIAL SYSTEM AND METHOD - A materials system and methods are provided to enable the formation of articles by 3D printing. In some embodiments, a materials system includes a substantially dry particulate material that includes an insoluble filler, a soluble filler, and a transition metal catalyst. The materials system further comprises a fluid binder including a (meth)acrylate monomer, an allyl ether functional monomer and/or oligomer, and a free-radical photoinitiator. | 09-18-2014 |
Magdi Moussa, Malden, MA US
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20100172867 | SUBSTITUTED 1H-PYRAZOLO[3,4-D]PYRIMIDINE-6-AMINE COMPOUNDS - The present invention relates to substituted 1H-pyrazolo-[3,4-d]pyrimidine-6-amine compounds and methods of synthesizing these compounds. The present invention also relates to pharmaceutical compositions containing substituted 1H-pyrazolo-[3,4-d]pyrimidine-6-amine compounds and methods of treating cell proliferative disorders, such as cancer, by administering these compounds and pharmaceutical compositions to subjects in need thereof. | 07-08-2010 |
20110160237 | Substituted Heterocyclic Compounds - The present invention relates to substituted heterocyclic compounds and methods of synthesizing these compounds. The present invention also relates to pharmaceutical compositions containing substituted heterocyclic compounds and methods of treating cell proliferative disorders, such as cancer, by administering these compounds and pharmaceutical compositions to subjects in need thereof. | 06-30-2011 |
20110245236 | Substituted Benzo-Pyrido-Triazolo-Diazepine Compounds - The present invention relates to substituted benzo-pyrido-triazolo-diazepine compounds and methods of synthesizing these compounds. The present invention also relates to pharmaceutical compositions containing substituted benzo-pyrido-triazolo-diazepine compounds and methods of treating cell proliferative disorders, such as cancer, by administering these compounds or pharmaceutical compositions to subjects in need thereof. | 10-06-2011 |
20140200199 | Compositions and Methods for Treatment of Cancer - The present invention relates to pyrroloquinolinyl-pyrrolidine-2,5-dione compounds in combination with chemotherapeutic agents. The present invention provides methods of treating a cell proliferative disorder, such as a cancer, by administering to a subject in need thereof a therapeutically effective amount of a pyrroloquinolinyl-pyrrole-2,5-dione compound or pyrroloquinolinyl-pyrrolidine-2,5-dione compound of the present invention and also administering a effective amount of a chemotherapeutic agent. | 07-17-2014 |
Magdi M. Moussa, Malden, MA US
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20100221251 | Compositions and Methods for Treatment of Cancer - The present invention relates to pyrroloquinolinyl-pyrrole-2,5-dione compounds and pyrroloquinolinyl-pyrrolidine-2,5-dione compounds, and methods of preparation of these compounds. The present invention also relates to pharmaceutical compositions comprising pyrroloquinolinyl-pyrrole-2,5-dione compounds and pyrroloquinolinyl-pyrrolidine-2,5-dione compounds. The present invention provides methods of treating a cell proliferative disorder, such as a cancer, by administering to a subject in need thereof a therapeutically effective amount of a pyrroloquinolinyl-pyrrole-2,5-dione compound or pyrroloquinolinyl-pyrrolidine-2,5-dione compound of the present invention. | 09-02-2010 |
20130150310 | Compositions and Methods for Treatment of Cancer - The present invention relates to pyrroloquinolinyl-pyrrolidine-2,5-dione compounds in combination with chemotherapeutic agents. The present invention provides methods of treating a cell proliferative disorder, such as a cancer, by administering to a subject in need thereof a therapeutically effective amount of a pyrroloquinolinyl-pyrrole-2,5-dione compound or pyrroloquinolinyl-pyrrolidine-2,5-dione compound of the present invention and also administering a effective amount of a chemotherapeutic agent. | 06-13-2013 |
Mehdi Si Moussa, Acton, MA US
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20140354370 | SIGNAL HANDLING APPARATUS FOR RADIO FREQUENCY CIRCUITS - A signal handler providing high linearity in a small size, applicable across wide operating frequencies and bandwidths, while also adapted to preferred integrated circuit (IC) and printed circuit board technologies. In one implementation, a signal handling apparatus includes an input impedance transformer for receiving an input signal and matching an internal apparatus impedance, a splitter for providing N split signals, a number of signal processing circuits for processing the N split signals, a combiner for combining the N split signals into a combined signal, and output impedance transformer for receiving the combined signal and for matching the internal apparatus impedance to an output impedance of the apparatus. The apparatus may provide filtering, duplexing and other radio frequency signal processing functions. A tunable duplexer may be implemented using a vector inductor and tunable capacitor array with frequency dependent impedance transformers. | 12-04-2014 |
20140354377 | VECTOR INDUCTOR HAVING MULTIPLE MUTUALLY COUPLED METALIZATION LAYERS PROVIDING HIGH QUALITY FACTOR - An inductor component includes a plurality of conductive elements, each formed as an individual patch of conductive material, with the conductive elements arranged in a vertical stack and tightly coupled to one another. Dielectric is disposed between more adjacent conductive elements, the dielectric has a permittivity and is sufficiently thin so as to provide a mutual inductance factor of at least one-half or greater between adjacent ones of the conductive elements. The dielectric is typically thinner than the adjacent conductors. | 12-04-2014 |
20140355171 | APPARATUS AND METHODS FOR VECTOR INDUCTORS - Apparatus and methods for vector inductors are provided herein. In certain configurations, an apparatus includes a vector inductor comprising a plurality of conductors arranged in a stack and separated from one another by dielectric. The conductors are tightly coupled to one another to provide a relatively high amount of mutual inductance. For example, adjacent conductors in the stack can be mutually coupled with a coupling coefficient k that is at least 0.5, or more particularly, 0.9 or greater. In certain implementations, the conductors are electrically connected in parallel with one another to provide the vector inductor with low resistance. However, tight coupling between the conductors in the stack can result in vector inductor having an overall inductance that is similar to that of a self-inductance of an individual conductor in the stack. The Q-factor of the vector inductor can be increased by the inclusion of additional conductors in the stack. | 12-04-2014 |
Michael Moussa, Euless, TX US
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20140319734 | REAL TIME MANUFACTURING OF SOFTENING POLYMERS - Embodiments of the invention is directed to a manufacturing process to mold and cast custom softening polymers into complex shaped devices, said process comprising the steps of: creating a 3D mold or shell; injecting the shell with a polymer or pre-polymer; cooling or curing the polymer in a short period of time; and forming a device. | 10-30-2014 |
Michael R. Moussa, Euless, TX US
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20110101679 | METHODS, SYSTEMS AND APPARATUSES FOR SEGMENTAL DUCT COUPLERS - The subject matter disclosed herein relates to methods, systems and apparatuses for segmental duct couplers for use during and after formation of concrete segments. Segmental duct coupling systems can include a number of components for coupling ducts both during and after formation of the concrete segments. In one aspect, the coupling system can include a locking member and forming member disposed between coupling ends of segmental ducts. In another aspect, a coupling system can include a deformable member disposed between coupling ends of ducts cast within pre-cast and match-cast concrete segments. | 05-05-2011 |
20110277868 | METHOD FOR REPAIRING AND STRENGTHENING PIPE WITH INTERNAL HELICALLY WOUND TENSILE REINFORCEMENT - A method for repairing and strengthening pipes by creating a structural reinforced composite liner within the existing pipe. The liner is created by helically winding a tensile reinforcement material on the inside wall of a pipe and encapsulating it in a hardening matrix material. The reinforcement material is helically wound around the inside wall of the pipe by an installation device. The installation device is configured to relieve and/or prevent the development of torsional stress in the reinforcement material that is created by the act of helically winding it onto the inside wall of a pipe, allowing the reinforcement material to lay flat against the pipe wall without twisting or buckling. The structural reinforced composite can be configured to supplement the strength of the existing pipe or to function as a stand-alone pipe within the existing pipe. | 11-17-2011 |
20110280665 | SYSTEM FOR REPAIRING AND STRENGTHENING PIPE WITH INTERNAL HELICALLY WOUND TENSILE REINFORCEMENT - A method for repairing and strengthening pipes by creating a structural reinforced composite liner within the existing pipe. The liner is created by helically winding a tensile reinforcement material on the inside wall of a pipe and encapsulating it in a hardening matrix material. The reinforcement material is helically wound around the inside wall of the pipe by an installation device. The installation device is configured to relieve and/or prevent the development of torsional stress in the reinforcement material that is created by the act of helically winding it onto the inside wall of a pipe, allowing the reinforcement material to lay flat against the pipe wall without twisting or buckling. The structural reinforced composite can be configured to supplement the strength of the existing pipe or to function as a stand-alone pipe within the existing pipe. | 11-17-2011 |
20140076588 | Flame Dispersant Canister Mounting System for Under-Microwave Location - A fire extinguisher apparatus and related system is described for automatically suppressing stovetop fires. The fire extinguisher apparatus includes a canister restrained in a first location where the canister is operable to suppress fires on a rear burner of a stovetop. The canister is biased and movable to a second location where the canister is operable to suppress fires on a front burner of the stovetop. A trigger mechanism is provided for automatically moving the canister to the second location in response to a fire on the front burner. The fire extinguisher system includes an arrangement of fire extinguisher apparatuses wherein canisters are movable between the apparatuses to prevent collisions with external obstacles. | 03-20-2014 |
Nader W. Moussa, Stanford, CA US
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20100281134 | ARCHITECTURE FOR A SELF-HEALING COMPUTER SYSTEM - The self-healing system comprises a self-healing processor and an error mitigation system. The self-healing processor includes a code block associated with the operation of a portion of digital logic. The self-healing processor also includes a dynamic signature analysis circuit. The processor executes the code block. The dynamic signature analysis circuit creates a dynamic signature representing the operation of the portion of digital logic associated with the code block. The error mitigation system receives the dynamic signature from the dynamic signature analysis circuit. The error mitigation system compares the dynamic signature to a static signature to determine if the signatures match. If the signatures do not match, then the digital logic associated with the code block has an error. The error mitigation system retries execution of the code block. The error mitigation system stores log information describing the above events. | 11-04-2010 |
Nader W. Moussa, Sunnyvale, CA US
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20150350549 | OPTICAL IMAGE STABILIZATION CALIBRATION - In some embodiments, a camera actuator module includes a linear actuator motor for moving a lens assembly, a position sensor coupled to the lens assembly, a mechanical end stop mounted in the path of motion of the lens assembly, and a non-transitory storage medium storing program instructions. In some embodiments, the program instructions are computer-executable to implement exciting, using the linear actuator motor, a mechanical resonance in the camera actuator module calculated to cause the lens assembly to move to an overload displacement by powering the linear actuator of the camera actuator module at a resonant frequency of the camera actuator module, measuring, using the position sensor, a current maximal displacement of the lens assembly during the exciting using a position sensor, and estimating a position of the mechanical end stop using at least the current maximal displacement. | 12-03-2015 |
Omar Moussa, Mount Pleasant, SC US
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20130344588 | DEVICES AND METHODS FOR CONCENTRATION AND ANALYSIS OF FLUIDS - Disclosed are articles, compositions and methods for detecting analytes. The disclosed articled, compositions and methods increase the ease of detection and quantitation of the target analyte. | 12-26-2013 |
Omar Moussa, Charleston, SC US
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20110117078 | Methods for the Treatment of Cancers - Methods for the treatment of cancers involving dysregulation of thromboxane receptor β (TP-β) are provided, including in certain aspects methods for diagnosing such cancers. Specific cancers included are genitourinary cancers, gastrointestinal cancers and leukemias. | 05-19-2011 |
Omar Moussa, Mt. Pleasant, SC US
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20100297627 | MicroRNA Diagnostics for Cancer - Disclosed are methods for detecting breast cancer or prostate cancer by measuring levels of miR-204 and miR-510 in samples. | 11-25-2010 |
Sarah Moussa, Los Altos, CA US
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20150161175 | ALTERNATIVE IMAGE QUERIES - Methods and systems for suggesting alternative image queries for individual image query search results. In one aspect, a method includes displaying a group of one or more image search results for a first image query, each image search result referring to a respective resource and including a link to the respective resource, receiving first input from a user interacting with a first image search result in the group of one or more image search results, and, in response to receiving the first input, displaying one or more suggested second image queries, where each suggested second image query is associated with the first image search result. | 06-11-2015 |
Sarah Moussa, Mountain View, CA US
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20150161168 | ORDERING IMAGE SEARCH RESULTS - Methods, systems, and apparatus, including computer program products, for ranking images are disclosed. An image search subsystem generates an adjustment factor representative of a quality measure of an image relative to a search query. The quality represents a relevance of the image to the query. The adjustment factor can be computed based on relevance data for the image to the query and image similarity data representing a relative similarity between the image and other images relevant to the query. The relevance data can be based on user actions in response to the image being included in search results for the query. The adjustment factor can be scaled based on whether the relevance data and the image similarity data both indicate that the image is relevant to the search query. A relevance score is computed based on the adjustment factor (e.g., a product of the adjustment factor and relevance score). | 06-11-2015 |
Yossef Moussa, Loveland, OH US
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20140131353 | COATED CONTAINERS - A coated container and a method for coating a container are disclosed. The coating on the container is derived from a composition comprising: | 05-15-2014 |
Youssef Moussa, Loveland, OH US
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20120301645 | COATING COMPOSITIONS WITH IMPROVED ADHESION TO CONTAINERS - A coating composition comprising a resinous binder and up to 10 percent by weight of the reaction product of (i) a phosphorus acid, and (ii) a polyglycidyl ether of cyclohexane dimethanol. The compositions are useful for coating containers of all sorts, such as food and beverage containers, and the reaction product provides enhanced adhesion of the coating to the substrate. The compositions can be formulated to be substantially free of bisphenol A (BPA) and derivatives thereof such as bisphenol A diglycidyl ether (BADGE). | 11-29-2012 |
20120301646 | COATING COMPOSITIONS FOR CONTAINERS - A coating composition comprising a polyether polyol having a hydroxyl functionality of 3 to 8 and the reaction product of: | 11-29-2012 |
20120301647 | PHOSPHATIZED POLYESTERS AND COATING COMPOSITIONS CONTAINING THE SAME - A coating composition comprising a resinous binder and up to 10 percent by weight of a phosphatized polyester. The compositions are useful for coating containers of all sorts such as food and beverage containers, and the phosphatized polyester provides enhanced adhesion of the coating to the container substrate. The compositions can be formulated to be substantially free of bisphenol A (BPA) and bisphenol A diglycidyl ether (BADGE). | 11-29-2012 |
20120302690 | GRAFTED ACRYLIC COMPRISING WATER SOLUBLE AND WATER INSOLUBLE PORTIONS AND LATTICES AND COATINGS COMPRISING THE SAME - A latex comprising of two stage grafted acrylic is disclosed. The acrylic comprises a water soluble portion and a water insoluble portion that are grafted together. A method for making the latex, a coating comprising the latex, and substrates coated with the coating are also disclosed. | 11-29-2012 |
20130280453 | CONTAINER COATING COMPOSITIONS - A coating composition comprising a polyester resin binder and a phosphatized polyester. The compositions are useful for coating containers such as food and beverage containers. The compositions have excellent hydrolytic stability upon storage at high temperature. The compositions are formulated to be substantially free of bisphenol A (BPA) and bisphenol A diglycidyl ether (BADGE). | 10-24-2013 |
20140322465 | COATING COMPOSITIONS COMPRISING 2,2'-BIPHENOL - A coating composition comprising a polyglycidyl ether of a 2,2′-biphenol that is substantially free of bisphenol A, bisphenol F and their derivatives and residues is disclosed. Food packages coated at least in part with such coatings are also disclosed. | 10-30-2014 |
20150110981 | CONTAINER COATING COMPOSITIONS - A coating composition for application to the surface of a container comprising: | 04-23-2015 |
20150218407 | ACRYLIC AQUEOUS DISPERSIONS FOR CONTAINER COATINGS - Acrylic aqueous dispersions useful in coating compositions for coating food and beverage containers are disclosed. The aqueous dispersion is the reaction product of: | 08-06-2015 |
20150225600 | GRAFTED ACRYLIC COMPRISING WATER SOLUBLE AND WATER INSOLUBLE PORTIONS AND LATTICES AND COATINGS COMPRISING THE SAME - A latex comprising of two stage grafted acrylic is disclosed. The acrylic comprises a water soluble portion and a water insoluble portion that are grafted together. A method for making the latex, a coating comprising the latex, and substrates coated with the coating are also disclosed. | 08-13-2015 |
Zaher Milad Moussa, Salem, MA US
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20120272663 | CENTRIFUGAL COMPRESSOR ASSEMBLY WITH STATOR VANE ROW - A compressor assembly for a gas turbine engine includes rotatable impeller with forward and aft ends, including: an annular hub defining a generally concave-curved cross-sectional inner flowpath surface at its radially outer periphery, the inner flowpath surface extending between an inlet and an exit; an annular array of airfoil-shaped inducer blades extending radially outward from the inner flowpath surface near the forward end; and an annular array of exducer blades extending outward from the inner flowpath surface, the array of exducer blades axially spaced apart from the array of inducer blades; a non-rotating shroud assembly surrounding the impeller and including a convex-curved outer flowpath surface, wherein the inner and outer flowpath surfaces cooperate to define a primary flowpath past the blades and the stator vanes; and an annular array of airfoil-shaped stator vanes extending radially inward from the outer flowpath surface into a space between the inducer and exducer blades. | 11-01-2012 |
Zeyad Moussa, San Diego, CA US
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20140137965 | RECONFIGURABLE APPAREL MANUFACTURE AND BUSINESS PROCESSES - Provided herein are methods for the modulation of appearance or material properties within items of apparel or equipment. Also provided herein are design articles having alterable designs. | 05-22-2014 |