Plum
Achim Plum, Berlin DE
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20090111707 | MARKERS FOR THE PREDICTION OF OUTCOME OF ANTHRACYCLINE TREATMENT - The present invention relates to methods for predicting the outcome of anthracycline treatment of cell proliferative disorder patients. This is achieved by determining the expression level of at least one gene selected from the group consisting of PITX2; TFF1 and PLAU. The invention also relates to sequences, oligonucleotides and antibodies which can be used within the described methods. | 04-30-2009 |
20090264302 | METHODS, SYSTEMS AND COMPUTER PROGRAM PRODUCTS FOR DETERMINING TREATMENT RESPONSE BIOMARKERS - The invention relates to methods for the identification of biomarkers suitable for determining patient treatment response as well as systems and computer program products of use in such methods. | 10-22-2009 |
Alexander Plum, Shanghai CN
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20140329333 | MICRO-SAMPLING-SYSTEM FOR SMALL AMOUNTS OF FLUID SAMPLES FOR ANALYSIS IN THE VAPOUR PHASE - Microsampling system for small amounts of fluid samples for analysis in the vapour phase, which comprises a plurality of integrated functional units and is suitable for small sample quantities with fast reaction times. | 11-06-2014 |
Anne Plum, Bikerod DK
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20110152185 | Pharmaceutical Compositions Comprising GLP-1 Peptides or Extendin-4 and a Basal Insulin Peptide - Pharmaceutical composition for parenteral administration comprising a basal insulin peptide and an insulinotropic GLP-1 peptide comprising at least 6 zinc atoms per 6 insulin molecules. | 06-23-2011 |
Anne Plum, Birkeroed DK
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20090074882 | INSULIN COMPOSITIONS AND METHOD OF MAKING A COMPOSITION - The invention is related to insulin compositions with a high content of zinc atoms per six molecules of acylated insulin. The insulin is an acylated insulin and may be mixed with a further insulin analogue such as the rapid acting insulin Asp B28 human insulin. | 03-19-2009 |
20140328943 | INSULIN COMPOSITIONS AND METHOD OF MAKING A COMPOSITION - The invention is related to insulin compositions with a high content of zinc atoms per six molecules of acylated insulin. The insulin is an acylated insulin and may be mixed with a further insulin analogue such as the rapid acting insulin Asp B28 human insulin. | 11-06-2014 |
Bartholomeus Johannes Margretha Plum, Ulestraten NL
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20100099786 | CARBAMATE, THIOCARBAMATE OR CARBAMIDE COMPRISING A BIOMOLECULAR MOIETY - The invention relates to a compound comprising (a) at least two polymerisable moieties, (b) at least one amino acid residue of an amino acid comprising at least two amine groups of which at least two amine groups have formed a carbamate, a thiocarbamate or a carbamide group, and (c) a biomolecular moiety linked directly or via a spacer to the carboxylic acid moiety of the diamino acid residue or a carboxylic acid to which such moiety can be linked. The invention further relates to a polymer obtainable from such compound. | 04-22-2010 |
20100291116 | MICROPARTICLE COMPRISING CROSS-LINKED POLYMER - Microparticle comprising a cross-linked polymer comprising (a) a cross-linker comprising two or more radically polymerizable groups, preferably selected from the group consisting of alkenes, sulfhydryl (SH), thioic, unsaturated esters, unsaturated urethanes, unsaturated ethers, and unsaturated amides; (b) a monofunctional reactive diluent comprising maximum one unsaturated C—C bond represented by the formula R | 11-18-2010 |
20110045530 | ENZYMATIC CONJUGATION OF BIOACTIVE MOIETIES - The present invention relates to a method for selective conjugation of bioactive moieties to a polymer or polymerisable compound. The method is more specifically related to the selective conjugation of bioactive moieties to a pendant carboxylic acid, ester or thioester group in which the pendant group is part of a polymer or a polymerisable compound, wherein the method comprises contacting the polymer or polymerisable compound with a hydrolytic enzyme to catalyse the conjugation between the bioactive moiety and the pendant carboxylic acid, ester or thioester group. The conjugation of the bioactive moieties may occur prior to, during or after polymerization of the polymerisable compound. The conjugation of the bioactive moieties may also occur after the polymer is given a form. | 02-24-2011 |
Dennis L. Plum, Hursley GB
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20090327486 | PROVIDING ACCESS BY A CLIENT APPLICATION PROGRAM OVER AN INTERNET PROTOCOL (IP) NETWORK TO A SERVER APPLICATION PROGRAM INSTANCE - A method, apparatus and software is disclosed in which a temporary IP address is assigned to a selected instance of a server application program so as to provide processing continuity for processing with a client application program. | 12-31-2009 |
Dennis L. Plum, Hertfordshire GB
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20130104151 | Interface Profiles for Customizing Application Programming Interface Behavior - Interface profiles are disclosed which specify at least a portion of the verbs and parameters of an existing application programming interface (“API”), and provide a mechanism for customizing behavior of the API, in response to receiving an invocation using the verb and/or parameter(s). The customizing may comprise altering which code executes, and/or how the code executes. An application that invokes a particular API therefore does not need to be changed, yet additional and/or different processing can be performed responsive to the invocation. | 04-25-2013 |
Dennis L. Plum, Bishop'S Stortford GB
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20130067069 | FLOW TOPOLOGY OF COMPUTER TRANSACTIONS - A visualization of a topology of a flow of multiple transactions is generated. A first computer system receives a current transaction initiation request from a precursory transaction. The current transaction initiation request is for an initiation of a current transaction in the first computer system, and the precursory transaction is part of a flow of other transactions that are upstream from the current transaction. The current transaction initiation request contains parameter information that holds a hop count, which identifies how many computer systems have received other transaction initiation requests in the flow of other transactions, and a transaction initiation count, which identifies how many transaction initiation requests have been transmitted in the flow of other transactions. A processor generates a visualization of a topology map of the current transaction and the other transactions based on information in the parameter information from the current transaction initiation request. | 03-14-2013 |
20130067074 | FLOW TOPOLOGY OF COMPUTER TRANSACTIONS - A visualization of a topology of a flow of multiple transactions is generated. A first computer system receives a current transaction initiation request from a precursory transaction. The current transaction initiation request is for an initiation of a current transaction in the first computer system, and the precursory transaction is part of a flow of other transactions that are upstream from the current transaction. The current transaction initiation request contains parameter information that holds a hop count, which identifies how many computer systems have received other transaction initiation requests in the flow of other transactions, and a transaction initiation count, which identifies how many transaction initiation requests have been transmitted in the flow of other transactions. A processor generates a visualization of a topology map of the current transaction and the other transactions based on information in the parameter information from the current transaction initiation request. | 03-14-2013 |
Eric Plum, Southampton GB
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20110261441 | Spectral Filter - This invention relates to use of metamaterials for creating spectral selectors of electromagnetic radiation. Planar metamaterial films patterned on the sub-wavelength scale can be used in polarization filters instead of natural and synthesized bulk crystals. Characteristics and the quality factor of metamaterial filters is controlled by the geometry of the pattern. Various types of metamaterials and filter configurations are proposed. | 10-27-2011 |
20120293854 | NON-LINEAR MATERIALS AND RELATED DEVICES - A non-linear optical device comprising a non-linear element made of a plasmonic material with a periodic structure having a period smaller than the wavelength of a non-linear process intrinsic to the plasmonic material. The plasmonic material is implemented as a gold film which is structured with a periodic array of asymmetric split ring slits. The metamaterial framework of the plasmonic material itself is used as the source of a strong and fast non-linearity. The cubic non-linear response is resonantly enhanced through the effect of the metamaterial structuring by more than two orders of magnitude and its sign and magnitude can be controlled by varying the metamaterial pattern. | 11-22-2012 |
20120327502 | TUNABLE METAMATERIALS AND RELATED DEVICES - A tunable metamaterial comprising a membrane on which is arranged a two-dimensional array of elements to form a metamaterial, wherein the array is subdivided into blocks of multiple elements, each block being separated from adjacent blocks by a gap to allow each block to be moveable relative to its adjacent blocks. The lattice of the metamaterial and hence its properties are tuned by inducing adjacent blocks to move away from each other or towards each other either in-plane or out-of-plane in a controllable manner in response to an electrical, thermal or optical control signal. | 12-27-2012 |
Hans-Dieter Plum, Aachen DE
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20120017952 | DISHWASHER - A dishwasher comprises a wash chamber, a water circulation system for passing water into and out of the wash chamber, and a water-collecting sump member ( | 01-26-2012 |
20120031442 | DISHWASHER - A dishwasher comprises a wash chamber and a water-collecting sump member which is fastened to an opening in a lower end portion of the wash chamber by means of a water-tight connection, wherein the sump member is made at least in part of plastics material and comprises at least one water inlet or outlet opening that is formed as an integral part of the sump member. The dishwasher comprises a water softening device and the sump member comprises a water inlet and an integrated first passage which is formed at least in part of plastics material as an integrally formed part of the sump member for passing water from the water inlet to the water softening device. | 02-09-2012 |
Hermann-Josef Plum, Juelich DE
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20120208920 | WATERBORNE ADHESIVE WITH IMPROVED WET ADHESION - A Waterborne adhesive comprising 1 to 50 weight-% of a (meth)acrylate copolymer manufactured by polymerization of at least one ester of methacrylic acid, acrylic acid, crotonic acid and/or itaconic acid with aliphatic alcohols, substituted aliphatic alcohols, aromatic alcohols, polyether glycols, and other copolymerizable monomers, having an acid number from 0 to 150 mgKOH/g, 0 to 40 wt-% of natural polymers 0.5 to 30 wt-% of urea, 0.1 to 20 wt-% of additives, characterized in that the adhesive contains 0.05 to 20 weight-% of a super absorbent polymer. | 08-16-2012 |
Horst Plum, Bergisch Gladbach DE
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20130163970 | HEATABLE MEDIUM PIPE AND METHOD FOR PRODUCING SAME - A heatable medium pipe having at least one pipe connector and heating element, wherein the heating element has a few wires, in particular two wires, and said wires extend continuously along the medium pipe and along the at least one pipe connector. In a method for producing such a heatable medium pipe, the heating element is continuously wound around a tubular medium pipe and the heating element is pre-assembled on the medium pipe in that the heating element is fastened or fixed by at least one fastening element, the medium pipe is cut to a first length for the particular application, the length corresponding to the desired medium pipe length (I | 06-27-2013 |
20130330065 | HEATABLE FLUID LINE, USE THEREOF AND METHOD FOR PRODUCING SAME - A heatable fluid line having a pipeline and an electrical heat conductor extending at least over a section of the pipeline. The pipeline has at least two longitudinal sections that are configured differently in respect of the material properties and/or design thereof. At least one first longitudinal section is formed of a first material and a second longitudinal section is formed of a second material. The material of the second longitudinal section is more flexible and/or has a higher resilience than the material of the first longitudinal section. A described method for producing the fluid line relates to an adaptive attachment of the heat conductor on the outside of the pipeline that permits the heat conductor to be wound around fluid coupling and/or connector parts, in particular the housings by means of which the line is assembled, without strand separation. | 12-12-2013 |
Karsten Plum, Assens DK
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20090200192 | PACKAGING UNIT AND A DISPENSER FOR DISPOSABLE ARTICLES - A packaging unit for holding a plurality of articles, preferably disposable articles, such, as plasters, tissues, gauze, etc. The packaging unit comprises a holding member ( | 08-13-2009 |
Lars B. Plum, Milpitas, CA US
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20110296135 | SYSTEM AND METHOD FOR FREEING MEMORY - There is provided a computer-executed method of freeing memory. One exemplary method comprises receiving a message from a user process. The message may specify a virtual address for a memory segment. The virtual address may be mapped to the memory segment. The memory segment may comprise a physical page. The method may further comprise identifying the physical page based on the virtual address. Additionally, the method may comprise freeing the physical page without unmapping the memory segment. | 12-01-2011 |
Lori Plum, Arena, WI US
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20090004133 | Methods and compositions for phosphate binding - The present invention provides improved methods and compositions for therapeutically controlling and/or reducing serum phosphate levels in animals and mammalian patients. The methods comprise administering to the patient an amount of a dendrimer composition effective to prevent absorption of substantial amounts of phosphate from the patient's GI tract. In a preferred version, a dose of between 2.5 and 15 grams per day is effective to prevent over 80% of phosphate present in the patient's GI tract from being absorbed. The dendrimer composition may comprise a hydrocitrate, hydrochloride, hydrobromide, hydroacetate or hydroanionic form. | 01-01-2009 |
20110034426 | Method of Preventing Renal Disease and Treating Symptoms Thereof - The invention relates to novel methods of using 2-methylene-19-nor-20(S)-1,25-dihydroxyvitamin D | 02-10-2011 |
20110124609 | Method of Preventing Type I Diabetes - The invention relates to novel methods of using 2α-methyl-19-nor-20(S)-1α,25-dihydroxyvitamin D | 05-26-2011 |
20120309719 | (22E)-2-METHYLENE-26,27-CYCLO-22-DEHYDRO-1ALPHA-HYDROXY-19-NORVITAMIN D3 DERIVATIVES - Cyclopropane-containing vitamin D analogs of formulas I and IV are provided. Such compounds may be used in preparing pharmaceutical compositions and are useful in treating a variety of biological conditions. | 12-06-2012 |
Lori A. Plum, Madison, WI US
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20080249068 | Method of Extending the Dose Range of Vitamin D Compounds - Inhibitors of bone calcium resorption are administered, and calcium intake in the subject's diet is restricted, to allow high doses of vitamin D compounds or mimetics to be given with the intent of treating diseases such as metabolic bone diseases, hyperparathyroidism, cancer, psoriasis, and autoimmune diseases without the dangers of calcification of kidney, heart, and aorta. Inhibitors of bone calcium resorption include the bis-phosphonates, OPG (osteoprotegerin) or the soluble RANKL (receptor activator of NF-κB ligand) receptor known as sRANK (soluble RANK which is the protein expressed by the NF-κB gene), and function to block the availability of calcium from bone thereby preventing hypercalcemia and the resulting calcification of soft tissues. Thus, high doses of 1α,25-dihydroxyvitamin D | 10-09-2008 |
Lort A. Plum, Arena, WI US
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20110105444 | ONCE-A-WEEK ADMINISTRATION OF 25-HYDROXY VITAMIN D3 TO SUSTAIN ELEVATED STEADY-STATE PHARMACOKINETIC BLOOD CONCENTRATION - An oral dosage form comprising a single dose of 25-hydroxy-vitamin D | 05-05-2011 |
Markus Plum, Mainz DE
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20150286778 | Methods of Evaluating Medical Measurement Curves, as Well as Computer Programs and Devices Therefor - Methods are provided for detecting an analyte concentration/presence in a body fluid sample that include providing a set of at least two different evaluation rules, each evaluation rule adapted to derive a set characteristic values from an optical measurement curve, where at least one first characteristic value is derived from at least one first evaluation rule and at least one second characteristic value is derived from at least one second evaluation rule. The methods also include performing at least one multivariate analysis of the at least one first and second characteristic values by using at least one predetermined multivariate evaluation algorithm to derive at least one estimate value for at least one target variable Y of the state variables. The methods also include determining at least one analyte concentration by using the at least one target variable Y. Also provided are computer programs and devices that incorporate the same. | 10-08-2015 |
Timothy Plum, Midland, MI US
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20130062958 | Low Profile Power Conversion System for Rooftop Photovoltaic Power Systems - The disclosed embodiments and principles provide a way to integrate high-efficiency, low-profile power electronics with localized maximum power point tracking (MPPT) into a rooftop shingle-based photovoltaic power system. DC-DC power converters having a height, or profile, as low as ¼ inch for a 200 W power output, are able to be included in a building-integrated photovoltaic (BIPV) roof shingle. The DC-DC power converters increase the relatively low voltage produced by two rows of series-connected photovoltaic shingles, each including photovoltaic cells, to a high voltage used by a DC-AC inverter. For example, DC-DC power converter increases the voltage produced by two rows of series-connected photovoltaic shingles from several tens of volts to approximately 400 volts. Thus, the DC-DC power converters provide a large voltage step-up using a low profile and with very high efficiency. | 03-14-2013 |
Timothy C. Plum, Midland, MI US
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20110094570 | DIRECT MOUNTED PHOTOVOLTAIC DEVICE WITH IMPROVED ADHESION AND METHOD THEREOF - The present invention is premised upon a photovoltaic device suitable for directly mounting on a structure. The device includes an active portion including a photovoltaic cell assembly having a top surface portion that allows transmission of light energy to a photoactive portion of the photovoltaic device for conversion into electrical energy and a bottom surface having a bottom bonding zone; and an inactive portion immediately adjacent to and connected to the active portion, the inactive portion having a region for receiving a fastener to connect the device to the structure and having on a top surface, a top bonding zone; wherein one of the top and bottom bonding zones comprises a first bonding element and the other comprises a second bonding element, the second bonding element designed to interact with the first bonding element on a vertically overlapped adjacent photovoltaic device to bond the device to such adjacent device or to the structure. | 04-28-2011 |
20120279150 | THROUGH ROOF CONNECTOR ASSEMBLY FOR A PHOTOVOLTAIC BUILDING SHEATHING ELEMENT - The present invention is premised upon a through-roof connector assembly comprising one or more photovoltaic building sheathing elements capable of being affixed on a building structure, the photovoltaic building sheathing element including a sheathing element electrical connector along a sheathing element peripheral edge; a through-roof connector edge piece assembly that abuts a portion of the photovoltaic building sheathing element and includes: a body portion, an edge piece electrical connector, one or more wire leads that are connected on one end to the edge piece electrical connector; a wire guiding member with at least one conduit hole, the wire guiding member located under the through-roof connector edge piece assembly when assembled; and an under-roof junction device that is removably connected to the wire guiding member. | 11-08-2012 |
20130170149 | CONNECTOR AND ELECTRONIC CIRCUIT ASSEMBLY FOR IMPROVED WET INSULATION RESISTANCE - The present invention is premised upon a connector and electronic circuit assembly ( | 07-04-2013 |
Todd Jackson Plum, Boise, ID US
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20090134491 | Semiconductor Constructions, Methods of Forming Capacitors, And Methods of Forming DRAM Arrays - Some embodiments include methods of forming capacitors. A first section of a capacitor may be formed to include a first storage node, a first dielectric material, and a first plate material. A second section of the capacitor may be formed to include a second storage node, a second dielectric material, and a second plate material. The first and second sections may be formed over a memory array region, and the first and second plate materials may be electrically connected to first and second interconnects, respectively, that extend to over a region peripheral to the memory array region. The first and second interconnects may be electrically connected to one another to couple the first and second plate materials to one another. Some embodiments include capacitor structures, and some embodiments include methods of forming DRAM arrays. | 05-28-2009 |
20110018098 | Semiconductor Constructions - Some embodiments include methods of forming capacitors. A first section of a capacitor may be formed to include a first storage node, a first dielectric material, and a first plate material. A second section of the capacitor may be formed to include a second storage node, a second dielectric material, and a second plate material. The first and second sections may be formed over a memory array region, and the first and second plate materials may be electrically connected to first and second interconnects, respectively, that extend to over a region peripheral to the memory array region. The first and second interconnects may be electrically connected to one another to couple the first and second plate materials to one another. Some embodiments include capacitor structures, and some embodiments include methods of forming DRAM arrays. | 01-27-2011 |
20120001299 | Semiconductor Constructions - Some embodiments include methods of forming capacitors. A first section of a capacitor may be formed to include a first storage node, a first dielectric material, and a first plate material. A second section of the capacitor may be formed to include a second storage node, a second dielectric material, and a second plate material. The first and second sections may be formed over a memory array region, and the first and second plate materials may be electrically connected to first and second interconnects, respectively, that extend to over a region peripheral to the memory array region. The first and second interconnects may be electrically connected to one another to couple the first and second plate materials to one another. Some embodiments include capacitor structures, and some embodiments include methods of forming DRAM arrays. | 01-05-2012 |
Wolfgang Plum, Kreuzau-Winden DE
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20090267012 | Sliding Valve - The invention relates to a slide valve, especially for controlling a flow of catalyst or like high-temperature media, having a pipe portion ( | 10-29-2009 |