Savran
Cagri Savran, West Lafayette, IN US
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20100330702 | ULTRASENSITIVE DETECTION OF BIOMOLECULES USING IMMUNOSEPARATION AND DIFFRACTOMETRY - Systems and methods for rapid and ultrasensitive detection of target hiomolecules in a sample are presented. The detection of biomolecules is achieved through a synergistic use of immunoseparation and diffractomctry, and the formation of antibody-biomolecule-ligand sandwich complexes that form diffraction gratings. Characteristic diffraction patterns are then produced upon illumination of the diffraction gratings with light. The diffraction patterns can he used to detect very low amounts of biomolecules present in the sample. | 12-30-2010 |
20120170050 | Reflective Diffractometric Hydrogel Sensor for Biological and Chemical Detection - A reflective diffractometric hydrogel sensor includes an upper layer, including a microfluidic chamber formed from a substantially transparent material and configured to contain a solution, a reflective diffraction grating positioned within the microfluidic chamber, the diffraction grating including a plurality of hydrogel strips configured to change in dimension in response to a stimulus, each hydrogel strip having a top surface coated with a reflective material and a bottom surface in contact with the upper layer substrate, and a reflective surface below the reflective diffraction grating wherein when a coherent light is incident upon and reflected from the upper layer at an angle substantially normal to the upper layer an interference diffraction pattern results, including a first diffraction mode, a light intensity of which indicates the relative distance between the top surfaces of the plurality of hydrogel strips and the reflective surface. | 07-05-2012 |
20130154292 | Mechanical Gripper for Manipulation of Micro-Sized Objects - An apparatus for the micromanipulation of micro-sized objects includes a micromanipulation device in the form of a hollow frame having a base, resiliently deflectable arms projecting from the base and defining a gap for receiving a micro-sized object, and a saddle connected to the tips of the arms between the base and the tips. A force generating device applies a force to the saddle to deflect the tips inwards to close the gap about the micro-sized object. A fixture is provided for supporting the micromanipulation device and force generating device. The force generating device can be a micrometer. The micromanipulation device is configured for production using micro-fabrication techniques. The micromanipulation device may include a piercing element for piercing an object positioned between the arms of the device, and may further include a notch aligned with the piercing element for retaining the object. | 06-20-2013 |
Cagri A. Savran, West Lafayette, IN US
Patent application number | Description | Published |
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20120241596 | System for and Method of Performing Multi-Technique Imaging - A system for and method of performing multi-technique imaging are disclosed. Such multi-technique imaging system includes a surface for supporting a specimen and at least two illumination sources for producing light radiation. The system also includes a plurality of reflective and refractive devices arranged to direct at least part of the light radiation from each of the at least two illumination sources to the surface such that the at least part of the light radiation from each of the at least two illumination sources illuminates substantially the same area on the surface. The system also includes a sensor configured to receive light radiation from the at least two illumination sources reflected by the specimen and/or that pass by the specimen. The system also includes a power source configured to power the at least two illumination sources and the sensor. | 09-27-2012 |
20140024049 | Micro-Fluidic System Using Micro-Apertures for High Throughput Detection of Cells - A microfluidic detection system for micrometer-sized entities, such as biological cells, includes a detector component incorporating a plate with a plurality of opening, the plate separating two chambers, one in communication with a fluid source containing target cells bound to magnetic beads. The openings are sized to always permit passage of the magnetic beads therethrough into a lower one of the chambers and are further sized to always prevent passage of the target cells from the upper one of the chambers. The detector component further includes a magnet positioned to pull unbound magnetic beads through the openings and to capture target cells bound to magnetic beads on the surface of the plate. The microfluidic detection system includes a pump flowing the fluid through the detector component at high flow rates of milliliters per minute for high throughput detection of target cells. | 01-23-2014 |
20140057289 | Micro-Fluidic System Using Micro-Apertures for High Throughput Detection of Cells - A microfluidic detection system for micrometer-sized entities, such as biological cells, includes a detector component incorporating a plate with a plurality of opening, the plate separating two chambers, one in communication with a fluid source containing target entities bound to magnetic beads. The openings are sized to always permit passage of the magnetic beads therethrough into a lower one of the chambers and are further sized to always prevent passage of the target entities from the upper one of the chambers. The detector component further includes a magnet positioned to pull unbound magnetic beads through the openings and to capture target entities bound to magnetic beads on the surface of the plate. In a further feature, the microfluidic detection system is configured to pass target molecules through the plate to be bound to a functionalized surface of the lower chamber. | 02-27-2014 |
Cagri Abdullah Savran, West Lafayette, IN US
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20150068309 | SYSTEM FOR WEIGHING INDIVIDUAL MICRO- AND NANO- SIZED PARTICLES - A device for weighing micro- and nano-sized particles. The device includes a base portion, an oscillator coupled to the base portion and configured to vibrate the base portion, a first cantilevered beam coupled to the base portion, a second cantilevered beam coupled to the base portion, a first plurality of fingers coupled to the first cantilevered beam near the tip inwardly pointing toward the second cantilevered beam, and a second plurality of fingers coupled to the second cantilevered beam near the tip inwardly pointing toward the first cantilevered beam. | 03-12-2015 |
Volodimir Savran, Lviv UA
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20090264841 | Drainage - Drainage belongs to medical equipment, particularly to medical tools and is specified for drainage of cavities. Drainage comprises a first tube, an additional tube, which is fixed upon it, a unit of the clot's splitter and the splitter's fixing element. The additional tube has a smaller diameter with an opening, inside which the conductor is mounted, a unit of clots splitter is installed on the working end of the drainage, it comprises a cylinder, a tube with an opening, placed on it, which is the continuation of the additional tube of the drainage and a spring with a cutter inside the cylinder. A cutter is located diametrically inside the working head, while in the end of the wall of the first tube and the splitter's unit comprises a channel, inside which splitter's fixing element was led, its working end is inside the unit's cylinder and fixes the splitter. This design ensures the permeability of the wound channel after the drainage is removed and it is possible to reinstall drainage into the cavity strictly along the existing wound channel. | 10-22-2009 |