Patent application number | Description | Published |
20090042743 | METHOD FOR DETERMINING CRYSTALLIZATION PARAMETERS AND APPARATUS FOR USE WITH THE SAME - The present disclosure provides a method to allow a user to pre-screen numerous crystallization conditions in the crystallization space to identify those conditions with the highest probability of yielding crystals and high quality diffracting crystals. In one embodiment, the dilute solution thermodynamic virial coefficient, termed B, is used to aid in the determination crystallization conditions that increase the probability of producing crystals for the crystallant of interest. The present disclosure also provide methods for predicting solution conditions that generate beneficial solubility and/or stability conditions for a polypeptide of interest using the B parameter. Devices for use in the described methods are also described. | 02-12-2009 |
20110284379 | DIRECT DETERMINATION OF CARBOHYDRATES, AMINO ACIDS AND ANTIBIOTICS BY MICROCHIP ELECTROPHORESIS WITH PULSED AMPEROMETRIC DETECTION - The present invention provides a microchip for performing electrophoresis with pulsed amperometric detection (PAD) for the separation and detection of underivatized carbohydrates, amino acids, sulfur-containing antibiotics, etc. PAD allows for the direct detection of amines, thiols, alcohols and carbohydrates and therefore is a useful technique for the development of electrochemical detection for microchip electrophoresis. | 11-24-2011 |
20120077248 | METHOD FOR DETERMINING CRYSTALLIZATION PARAMETERS AND APPARATUS FOR USE WITH THE SAME - The present disclosure provides a method to allow a user to pre-screen numerous crystallization conditions in the crystallization space to identify those conditions with the highest probability of yielding crystals and high quality diffracting crystals. In one embodiment, the dilute solution thermodynamic virial coefficient, termed B, is used to aid in the determination crystallization conditions that increase the probability of producing crystals for the crystallant of interest. The present disclosure also provide methods for predicting solution conditions that generate beneficial solubility and/or stability conditions for a polypeptide of interest using the B parameter. Devices for use in the described methods are also described. | 03-29-2012 |
20120238008 | Rapid Detection of Pathogens Using Paper Devices - A kit for the rapid detection of pathogens in food supplies. The kit includes a microspot device and one or more indicator reagents to be applied to a well of the microspot device. The employed indicator reagent produces a detectable change upon contact with a pathogen of interest. The microspot device is fabricated from a porous membrane, such as filter paper. A substantially continuous boundary composed of a low melting temperature solid is deposited within the porous membrane extending from the top of the membrane to the bottom of the membrane and defines the peripheral sides of the well. Additionally, a barrier is applied to the bottom of the membrane, thus defining the bottom of the well. The kit can further include growth media for enriching the pathogenic bacteria and instructions for use of the kit employing the microspot device and the one or more indicator reagents. | 09-20-2012 |
20140178978 | DISTANCE-BASED QUANTITATIVE ANALYSIS USING A CAPILLARITY-BASED ANALYTICAL DEVICE - Apparatus for quantitative analytical measurements using capillarity-based analytical devices is described. Porous cellulose (i.e., common filter paper) may be used as the reagent carrier for the analyses. Hydrophobic materials may be printed onto the paper to generate paths that restrict liquid flow by capillary action to defined regions. At least one colorimetric reagents effective for reacting with a specific analyte is deposited along a capillary flow path generated in the device. Upon placing the liquid containing the analyte on one end of the path, the liquid moves along the circuit by capillary action, and the flowing analyte reacts with reagent generating color along the flow path until all of the analyte is consumed. Analyte quantification is achieved by measuring the length of the colored portion along a flow path employing a direct-reading measurement scale. Analyses are demonstrated for chemical detection modalities including: enzymatic action, metal complexation, and nanoparticle aggregation, but the present apparatus may be used for a wide range of analytes. | 06-26-2014 |
20150283384 | TONGUE STIMULATION FOR COMMUNICATION OF INFORMATION TO A USER - Example devices and methods of tongue stimulation for communication of information to a user are disclosed herein. In an example, a tongue stimulation device may include a body configured to be placed entirely within a mouth of the user and atop the tongue of the user. An array of electro-tactile elements may be distributed on the body, wherein each of the electro-tactile elements is configured to stimulate an area of the tongue adjacent the electro-tactile element. A wireless receiver coupled to the body may be configured to receive stimulation information wirelessly from outside the mouth of the user. At least one processing unit coupled to the body may be configured to transform the received stimulation information into a stimulation signal for each of the electro-tactile elements, and to provide the stimulation signals to the electro-tactile elements. | 10-08-2015 |
Patent application number | Description | Published |
20120130228 | Medical Device Location Systems, Devices and Methods - Methods, devices and systems for one or both of two- or three-dimensional location of the disposition of a sensor coil in a subject including: an array of electromagnetic drive coil sets, each set having two or three dimensionally oriented drive coils; a sensor coil being electromagnetically communicative with the array of electromagnetic drive coil sets; and, a system controller communicative with and adapted to energize one or more of the electromagnetic coils in the array of electromagnetic drive coil sets, the energizing of the one or more of the electromagnetic coils including one or more of energizing the coils singly, or in pairs of x-y and y-z or x-z coils, or in triplets of x-y-z coils while measuring the response of the sensor coil; whereby the system uses the measurements of the responses of the sensor coil to calculate the location and orientation of the sensor coil relative to said drive coil sets. | 05-24-2012 |
20120130229 | Medical Device Location Systems, Devices and Methods - Methods, devices and systems for one or both of two- or three-dimensional location of the disposition of a sensor coil in a subject including: an array of electromagnetic drive coil sets, each set having two or three dimensionally oriented drive coils; a sensor coil being electromagnetically communicative with the array of electromagnetic drive coil sets; and, a system controller communicative with and adapted to energize one or more of the electromagnetic coils in the array of electromagnetic drive coil sets, the energizing of the one or more of the electromagnetic coils including one or more of energizing the coils singly, or in pairs of x-y and y-z or x-z coils, or in triplets of x-y-z coils while measuring the response of the sensor coil; whereby the system uses the measurements of the responses of the sensor coil to calculate the location and orientation of the sensor coil relative to said drive coil sets. | 05-24-2012 |
Patent application number | Description | Published |
20090018416 | Analyte Concentration Measurement Device - A method for measuring concentration of an analyte in body fluid comprises acquiring a body fluid sample, emitting light into the body fluid sample, and detecting emitted light intensity on a plurality of optical paths through the body fluid sample. A plurality of optical filters are arranged in respective optical paths of the optical path plurality comprising at least a first optical filter with light absorption by an analyte and water and a second optical filter with light absorption to water alone. Light intensity passed through the first optical filter and passed through the second optical filter is measured and analyte concentration is determined based on a ratio of intensities detected at a detector in an optical path intersected by the first optical filter and detected at a detector in an optical path intersected by the second optical filter. | 01-15-2009 |
20090018483 | Infrared Sample Chamber - A body fluid analysis apparatus comprises a unitary housing containing a single-celled chamber and having an entry portal for communicating body fluid between a patient body and the chamber. A barrier coupled at the entry portal prevents selected components of the body fluid from entering the chamber. | 01-15-2009 |
20090047177 | LACTATE CONCENTRATION MEASUREMENT DEVICE - A lactate concentration measurement apparatus comprising a housing enclosing a sample chamber configured for holding a body fluid sample and measurement photo-optics that generate light and monitor light intensity along a plurality of optical paths in the sample chamber. The apparatus further comprises a plurality of optical filters aligned in respective optical paths of the optical path plurality comprising at least a first optical filter with light absorption by lactate and water and a second optical filter with light absorption to water alone. A logic determines lactate concentration based on a ratio of intensities detected at a first detector in an optical path intersected by the first optical filter and detected at a second detector in an optical path intersected by the second optical filter. | 02-19-2009 |
20090264724 | SERUM SAMPLING APPARATUS AND CATHETER - In a serum measurement device, an analyte concentration measurement apparatus facilitates sampling and analysis of analytes in body fluid and includes an implantable serum sampling catheter comprising a biocompatible tubing enclosing a vacuum release lumen and a serum lumen that are interconnected by a port. The serum lumen is separated from the sampling catheter exterior by a membrane barrier. The sampling catheter is configured for drawing a serum sample from a body fluid compartment by creation of suction in the serum lumen. | 10-22-2009 |
Patent application number | Description | Published |
20090260846 | CABLE PROTECTOR WITH REMOVABLE DIVIDERS - A cable protector includes a channel recessed into, and extending along the upper surface of a base. A number of dividers can be removably inserted into the channel from above to divide the channel into a plurality of tracks for carrying cables that can be inserted from above. Alternatively, a removable tray with a desired number of dividers can be placed as a unit in the channel, instead of inserting individual dividers. A lid covers the channel and dividers to provide a surface for traffic over the cable protector. Sets of complementary fasteners, such a tabs and keyed slots, can be employed to removably secure the dividers in the channel of the cable protector. | 10-22-2009 |
20110168501 | WHEEL CHOCK WITH SOLAR-POWERED LIGHTS - A wheel chock assembly includes a self-contained, solar-powered lighting module held in a recess on an external surface of the wheel chock. The protective panel can be used to cover the lighting module. The lighting module includes photovoltaic cells for generating electricity from sunlight, light-emitting diodes (LEDs), and an energy-storage device (e.g., batteries or capacitors) for storing excess electrical energy to power the LEDs at night. | 07-14-2011 |
20110171852 | MODULAR COVER FOR CABLE CONNECTORS AND ACCESSORIES - A cable connector cover for use with modular cable protectors includes a bottom recess for housing cables and cable connectors. The cable protector cover also has a number of openings to provide access into the bottom recess. These openings are adjacent to the connectors and are aligned with the channels of the cable protectors to allow cables to run from the cable protectors into the recess. The upper portion of the cable connector cover can extend upward to a sufficient height to provide a visual indicator to passersby. | 07-14-2011 |