Warnecke
Andre Warnecke, Freiburg DE
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20100041615 | PROTEIN-BINDING METHOTREXATE DERIVATIVES, AND MEDICAMENTS CONTAINING THE SAME - The invention relates to methotrexate derivatives which contain a protein-binding group and can be enzymatically cleaved in the body such that the active substance or a low-molecular active substance derivative is released. Also disclosed is a method for producing methotrexate derivatives, the use thereof, and medicaments comprising methotrexate derivative. | 02-18-2010 |
20120094892 | PRODRUGS - The present invention relates to a prodrug comprising at least one cytostatic agent, wherein said prodrug is cleavable by prostate-specific antigen (PSA), a process for preparing said prodrug and a pharmaceutical composition containing said prodrug in a pharmaceutically effective amount, for use in the treatment of cancer. | 04-19-2012 |
20150023912 | COMBINATIONS OF ALBUMIN-BASED DRUG DELIVERY SYSTEMS - The present invention relates to a composition comprising at least two different albumin-based drug delivery systems, as well as to a pharmaceutical composition comprising said composition. | 01-22-2015 |
André Warnecke, Freiburg DE
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20120142711 | ACID-LABILE TRIGGER UNITS - The present invention relates to a compound comprising an imine bond as an acid-labile trigger group, the use of such an imine bond as an acid-labile trigger group, a process of cleaving the imine bond in said compound, and a pharmaceutical composition comprising said compound. | 06-07-2012 |
20120270937 | LINEAR SELF-ELIMINATING OLIGOMERS - The present invention relates to a linear self-eliminating oligomer comprising one or more cleavable triggers, linker units, effector units and a carrier, and a pharmaceutical composition comprising said oligomer. | 10-25-2012 |
Falk Warnecke, Berkeley, CA US
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20110296543 | NUCLEIC ACIDS AND PROTEINS AND METHODS FOR MAKING AND USING THEM - The invention provides polypeptides, including enzymes, structural proteins and binding proteins, polynucleotides encoding these polypeptides, and methods of making and using these polynucleotides and polypeptides. Polypeptides, including enzymes and antibodies, and nucleic acids of the invention can be used in industrial, experimental, food and feed processing, nutritional and pharmaceutical applications, e.g., for food and feed supplements, colorants, neutraceuticals, cosmetic and pharmaceutical needs. Polypeptides of the invention can be used in food processing, brewing, bath additives, alcohol production, peptide synthesis, enantioselectivity, hide preparation in the leather industry, waste management and animal degradation, silver recovery in the photographic industry, medical treatment, silk degumming, biofilm degradation, biomass conversion to a biofuel (e.g., a bioethanol, biomethanol, biopropanol or biobutanol, a biodiesel, etc.), biodefense, antimicrobial agents and disinfectants, personal care and cosmetics, biotech reagents, in corn wet milling and pharmaceuticals such as digestive aids and anti-inflammatory (anti-phlogistic) agents. | 12-01-2011 |
Henning Warnecke, Osnabruck DE
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20120121579 | TREATMENT OF ONCOSTATIN M RECEPTOR BETA MEDIATED HEART FAILURE - The present invention relates to an inhibitor of the oncostatin M receptor β or an inhibitor of an activator of the oncostatin M receptor β for use in the treatment and/or prevention of heart failure. The present invention also relates to a method of treating and/or preventing heart failure comprising administering a pharmaceutically effective amount of an inhibitor of the oncostatin M receptor β or an inhibitor of an activator of the oncostatin M receptor β to a subject in need thereof. Further, the present invention also relates to methods of identifying a compound suitable as a lead compound and/or as a medicament for the treatment and/or prevention of heart failure. | 05-17-2012 |
Juergen Warnecke, Oldenborstel DE
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20130197089 | COMPOSITIONS FOR THE TREATMENT OF ACTINIC KERATOSIS - Ibuprofen can be used in the prevention and treatment of actinic keratosis. | 08-01-2013 |
Kai Warnecke, Warnecke DE
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20090255932 | VENTING COVER AND CONTAINER WITH SUCH VENTING COVER - Pressure release container, e.g. for peroxide materials, with a spout opening ( | 10-15-2009 |
Lawrence Warnecke, Ladner CA
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20080222800 | Drain Support Plate/Under-Deck Clamp - A drain support plate for mounting and securing a drain assembly to a deck in a building structure. | 09-18-2008 |
Melvin O. Warnecke, Goodlettesville/ridgetop, TN US
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20090061069 | High Protein Caramel Flavored Confection - A caramel flavored confection with high protein content, and methods for making the confection. | 03-05-2009 |
Robert C. Warnecke, Kildeer, IL US
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20110120885 | COOLING TOWER WATER MANAGEMENT SYSTEM - A cooling tower water management system is disclosed. A water treatment module is positioned in a water circulation line in a cooling tower. The water treatment module comprises a treatment cell having a cathodic tube and an anodic rod within the tube. A controller and power supply create a pulsed electrical potential across water in the treatment cell from the cathode to the anode to perform electrolysis on the water. Suspended and dissolved solids in the water are built up on a surface within the treatment cell. The controller can initiate a regeneration cycle to remove the built up solids from the surface. The regeneration comprises switching the electrical contact from the anode to a portion of the cathodic tube. | 05-26-2011 |
Ronald G. Warnecke, Fairview, OR US
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20110264335 | ROBUST CONTROL FOR ENGINE ANTI-STALL - A processing device is configured to identify an initial engine speed of an industrial vehicle and monitor a rate of change in engine speed. A variable hydraulic flow device is configured to vary a hydraulic flow associated with a hydraulic system based, in part, on the rate of change in the engine speed. The engine speed may be maintained at or below the initial engine speed while the hydraulic flow is varied. | 10-27-2011 |
Ronald R. Warnecke, Idaho Falls, ID US
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20090050718 | Method for Micro-sizing Organic, Inorganic and Engineered Compounds - A method and system are provided herein for forming microparticles from plastic and elastomeric materials that cannot be reduced in size by conventional methods. The system includes a high-pressure liquid nitrogen energy source, a feeder for providing a preferred constant and uninterrupted feed to a mill, a preferred integral injection device to meter the feed into a chamber for milling and/or classification, and a preferred exhaust system for collection of the milled product. | 02-26-2009 |
Russell A. Warnecke, Colorado Springs, CO US
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20080253131 | LIGHT DIMMER AND ASSOCIATED METHODOLOGY - A light dimming apparatus for dimming light output generated by a light source. A rectangular frame supports sets of blade members at a central aperture defined by the frame. The blade members of a set are positioned side-by-side, and adjacent ones of the blade members are hingedly connected together. Accordion-like movement of the blade members is provided responsive to application of forces applied to the blade members. A component of the applied forces causes linear translation of the blade members in to or out of the central aperture. | 10-16-2008 |
Scott Warnecke, Brighton, MI US
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20150233437 | BRAKE ROTOR RETAINING TOOL - A brake rotor retaining tool includes a main body having a first end, a second end with a bore extending from the first end and a grip portion. The bore has a non-threaded surface portion and a threaded surface portion. The non-threaded surface portion of the bore extends from the first end of the main body between the first end of the main body to the threaded surface portion. The non-threaded surface portion also has a first overall length measured in an axial direction of the bore. The threaded surface portion of the bore extends from the non-threaded surface portion toward the second end of the main body and has a second overall length measured in the axial direction of the bore. The first overall length is greater than the second overall length. | 08-20-2015 |
Svenja Warnecke, Mannheim DE
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20110137023 | METHOD FOR PRODUCING PHOSPHATE-BRIDGED NUCLEOSIDE CONJUGATES - The invention relates to a method for producing phosphate-bridged nucleoside conjugates. In the method a nucleophile is first dissolved in a non-aqueous solvent and dried, and a cyclosaligenyl phosphate compound is subsequently added to the solution. | 06-09-2011 |
Svenja Warnecke, Nahe DE
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20140296341 | FORMULATIONS BASED ON SOLID DISPERSIONS - The present invention relates to formulations comprising a solid dispersion product of an active agent having at least one of a hydrogen bond donor moiety (e.g. ibuprofen, fenofibric acid or naproxen) and a proton donor moiety and a pharmaceutically acceptable polyvinyllactam polyvinylacetate poly(alkylene glycol) graft copolymer, and to methods for preparing such formulations. | 10-02-2014 |
Wilhelm Warnecke, Hamminkeln DE
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20080308191 | Process For Melt Dip Coating a Strip of High-Tensile Steel - A process for melt dip coating a strip of high-tensile steel with alloy constituents including zinc and/or aluminum includes the following steps. The strip is heated in a continuous furnace initially in a reductive atmosphere to a temperature of approximately 650° C., at which the alloy constituents diffuse to the surface in small amounts. The surface, consisting predominantly of pure iron, is converted into an iron oxide layer by a short heat treatment at a temperature of up to 750° C. in a reaction chamber which is integrated in a continuous furnace and has an oxidizing atmosphere. In a subsequent annealing treatment at a higher temperature in a reductive atmosphere, this iron oxide layer prevents the alloy constituents from diffusing to the surface. In the reductive atmosphere, the iron oxide layer is converted into a pure iron layer to which the zinc and/or aluminium are applied in the molten bath with optimum adhesion. | 12-18-2008 |
20090199931 | Method for Melt Immersion Coating of a Flat Steel Product Made of High Strength Steel - A method for coating a flat steel product manufactured from a high strength steel with a metallic coating, wherein the flat steel product is initially subjected to a heat treatment, in order then, in the heated state, to be hot-dip galvanized with the metallic coating in a melting bath containing overall at least 85% zinc and/or aluminum. The heat treatment includes heating the steel product in a reducing atmosphere, followed by converting a surface of the flat product to an iron oxide layer by a heat treatment lasting 1 to 10 secs in an oxidizing atmosphere, followed by annealing in a reducing atmosphere over a period of time which is longer than the duration of the formation of the iron oxide layer such that the iron oxide layer is reduced at least on its surface to pure iron, followed by cooling the product to a melting bath temperature. | 08-13-2009 |
20100024925 | Steel Sheet Product Provided with an Anticorrosion Coating and Process for Producing It - A flat steel product, and a method for its production, which is formed from a steel substrate, such as strip or sheet steel, and a zinc-based corrosion protection coating, applied to at least one side of the steel substrate, which contains (in wt. %) Mg: 0.25 to 2.5%, Al: 0.2 to 3.0%, Fe: ≦4.0%, and optionally in total up to 0.8% of one or more elements of the group Pb, Bi, Cd, Ti, B, Si, Cu, Ni, Co, Cr, Mn, Sn and rare earths, remainder zinc and unavoidable impurities are described. The corrosion protection coating has an Al content of maximum 0.5 wt. % in an intermediate layer extending between a surface layer directly adjacent to the surface of the flat steel product and a border layer adjacent to the steel substrate and with a thickness amounting to at least 20% of the total thickness of the corrosion protection coating. | 02-04-2010 |
20100294400 | METHOD FOR PRODUCING A STEEL COMPONENT BY HOT FORMING AND STEEL COMPONENT PRODUCED BY HOT FORMING - A method for producing a steel component provided with a metallic coating which protects against corrosion, comprising the following steps: | 11-25-2010 |
20110017362 | STEEL FLAT PRODUCT HAVING A METALLIC COATING WHICH PROTECTS AGAINST CORROSION AND METHOD FOR PRODUCING A METALLIC ZN-MG COATING, WHICH PROTECTS AGAINST CORROSION, ON A STEEL FLAT PRODUCT - A steel flat product having a Zn—Mg—Al coating. The coating, which in addition to zinc and unavoidable impurities, comprises in wt. %: Mg: 4-8%, Al: 0.5-1.8% and optionally one or more of the following: Si: <2%, Pb: <0.1%, Ti: <0.2%, Ni: <1%, Cu: <1%, Co: <0.3%, Mn: <0.5%, Cr: <0.2%, Sr: <0.5%, Fe: <3%, B: <0.1%, Bi: <0.1%, Cd: <0.1%, REM<0.2%, and Sn<0.5%. The steel flat product according to the invention is not only outstandingly protected against corrosion, but also welds well and coats well with an organic layer applied subsequently. The invention also relates to a method for producing a steel flat product having a Zn—Mg—Al coating. | 01-27-2011 |
20120085466 | Method For Producing A Steel Component By Hot Forming And Steel Component Produced By Hot Forming - A method for producing a steel component provided with a metallic coating which protects against corrosion, in which a steel flat product, produced from an alloyed heat-treated steel, is coated with an Al coating which contains ≧85% wt. Al and optionally ≦15% wt. Si, a Zn coating with ≧90% wt. Zn, and a top layer, the main constituent of which is at least one metal salt of phosphoric acid or diphosphoric acid and which additionally can contain contents of up to 45% of an Al:Zn ratio as well as optionally metal oxides, metal hydroxides and/or sulphur compounds, the steel flat product is heat treated at ≧750° C., and the steel component is hot-formed from the heated steel flat product. The hot-formed steel component is cooled at a cooling rate sufficient to form a tempered or martensitic structure. | 04-12-2012 |
20120125491 | Method for the Hot-Dip Coating of a Flat Steel Product Containing 2 - 35 wt.% of Mn, and a Flat Steel Product - A method by which a flat steel product containing 2-35 wt. % of Mn can be provided with a coating of Zn which adheres well by annealing at an annealing temperature T | 05-24-2012 |
20120164472 | Method of Producing a Steel Component Provided with a Metallic Coating Giving Protection Against Corrosion, and a Steel Component - A method by which a steel component can be produced, which is provided with a metallic coating which adheres well and which provides protection against corrosion, from a flat steel product produced from a steel material containing 0.3-3 wt.-% manganese and having a yield point of 150-1100 MPa and a tensile strength of 300-1200 MPa coated with an anti-corrosion coating which comprises a coating of ZnNi alloy which is electrolytically deposited on the flat steel product, which coating is composed in a single phase of γ-ZnNi phase and which contains, as well as zinc and unavoidable impurities, 7-15 wt.-% nickel. | 06-28-2012 |
20130180305 | Method for Producing a Flat Steel Product which can be Readily Formed, Flat Steel Product and Method for Producing a Component from such a Flat Steel Product - A readily formable flat steel product has a ductile edge layer that is from 10 to 200 μm thick and has a ductility greater than a ductility of an inner core layer of the flat steel product. The readily formable flat steel product is produced by annealing a flat steel product having a C content of from 0.1 to 0.4% by weight in a continuous furnace. The annealing is carried out under an annealing atmosphere that contains from 0.1 to 25% by vol. of H | 07-18-2013 |