Fann, US
Henry H. Fann, Atlanta, GA US
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20120330830 | SYSTEM AND METHOD FOR CREATING AND MANAGING A STORED VALUE ACCOUNT ASSOCIATED WITH A CLIENT UNIQUE IDENTIFIER - A method and system for creating and managing a stored value account associated with a client device is disclosed. A first stored value and an associated first virtual token may be created. A graphical representation of the first virtual token may be displayed on a display of a client device. An exchange request may be received, and a second stored value account may be created along with an associated second virtual token. Next, an animation that includes a transition from the first virtual token to the second virtual token may be displayed on the display of the client device. The animation may include a peel-off effect in which the first virtual token appears to curl away to reveal the second virtual token when the first virtual token has been exchanged for the second virtual token. | 12-27-2012 |
Hilda Z. Fann, Santa Ana, CA US
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20090299470 | Quick-Release Annuloplasty Ring Holder - A holder for an annuloplasty ring having a template defining a proximal face opposite the distal face, and a peripheral edge about which the annuloplasty ring conforms. The annuloplasty ring anchors to the template using one or more flexible filaments. The template includes a single cutting well on its proximal face over which the flexible filament is suspended. Desirably, the single cutting well is located adjacent the peripheral edge so as to be away from any handle connections for ease of access. The flexible filament emerges above the proximal face of the template at only one location at the cutting well, thus presenting a one cut quick-release structure that is highly visible to the surgeon. The annuloplasty ring may have a relatively rigid inner core surrounded by a suture-permeable cover, and the peripheral edge may be formed by a lower axial wall and an upper radial ledge that projects outward from the rigid inner core but not quite as far as a sewing margin of the ring. The ring and holder may be for mitral annuloplasty rings and generally have a D shape in plan view, and may be three-dimensional with upward anterior and posterior bows. | 12-03-2009 |
20120179245 | METHODS OF ASSEMBLING AND DELIVERING AN ANNULOPLASTY RING - A holder for an annuloplasty ring having a template defining a proximal face opposite the distal face, and a peripheral edge about which the annuloplasty ring conforms. The annuloplasty ring anchors to the template using one or more flexible filaments. The template includes a single cutting well on its proximal face over which the flexible filament is suspended. Desirably, the single cutting well is located adjacent the peripheral edge so as to be away from any handle connections for ease of access. The flexible filament emerges above the proximal face of the template at only one location at the cutting well, thus presenting a one cut quick-release structure that is highly visible to the surgeon. | 07-12-2012 |
Hilda Zhang Fann, Santa Ana, CA US
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20110015727 | Annuloplasty Ring and Holder Combination - An annuloplasty ring holder includes an angled post for improved visibility and access by the surgeon. The post may be configured to be adjusted in angle and rotation. The ring holder can include a relatively open lower template, including relatively narrow extending radial arms with short, generally arcuate ring-retaining distal portions. The invention includes placements of suture holes and cutting wells which, in combination with improved suture routing, afford the user improved access to cutting the suture that is used to retain the annuloplasty ring to the holder. Another annuloplasty ring and ring holder combination disclosed includes a generally triangular-shaped ring and a generally T-shaped holder. The ring holder has a base portion forming the top of the T shape and engaging against a first segment of the ring, with a radial arm extending from the base portion and forming the post of the T. The radial arm engages against a junction between two segments of the ring. | 01-20-2011 |
James I. Fann, Portola Valley, CA US
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20120165930 | SYSTEM FOR MITRAL VALVE REPAIR AND REPLACEMENT - Systems for mitral valve repair are disclosed where one or more mitral valve interventional devices may be advanced intravascularly into the heart of a patient and deployed upon or along the mitral valve to stabilize the valve leaflets. The interventional device may also facilitate the placement or anchoring of a prosthetic mitral valve implant. The interventional device may generally comprise a distal set of arms pivotably and/or rotating coupled to a proximal set of arms which are also pivotably and/or rotating coupled. The distal set of arms may be advanced past the catheter opening to a subannular position (e.g., below the mitral valve) and reconfigured from a low-profile delivery configuration to a deployed securement configuration. The proximal arm members may then be deployed such that the distal and proximal arm members may grip the leaflets between the two sets of arms to stabilize the leaflets. | 06-28-2012 |
20120203330 | METHOD OF POST-OPERATIVE ADJUSTMENT FOR MITRAL VALVE IMPLANT - The present invention is directed to a mechanism and procedure for adjusting a cardiac implant during the early post-operative period, such as, for example, the first 2-5 days after surgery. During the implant procedure, an adjustment tool is releasably attached to the adjustable implant. The adjustment tool remains connected to the implant following the procedure and extends from the patient's body to allow for post-operative adjustment under normal beating heart conditions. Once the implant is adjusted, the adjustment tool is configured to release from the implant and be removed from the patient's body without requiring access to the patient's heart. | 08-09-2012 |
20130345802 | IMPLANTABLE DEVICES FOR CONTROLLING THE SIZE AND SHAPE OF AN ANATOMICAL STRUCTURE OR LUMEN - An implantable device system for controlling the dimensions of internal anatomic passages corrects physiologic dysfunctions resulting from a structural lumen which is either too large or too small. Implantable devices are disclosed which employ various mechanisms for adjusting and maintaining the size of an orifice to which they are attached. Systems permit he implants to be implanted using minimally invasive procedures and permit final adjustments to the dimensions of the implants after the resumption of normal flow of anatomic fluids in situ. | 12-26-2013 |
20140336756 | METHODS AND APPARATUS FOR CONTROLLING THE INTERNAL CIRCUMFERENCE OF AN ANATOMIC ORIFICE OR LUMEN - An implantable device is provided for controlling at least one of shape and size of an anatomical structure or lumen. An implantable device has an adjustable member configured to adjust the dimensions of the implantable device. An adjustment tool is configured to actuate the adjustable member and provide for adjustment before, during and after the anatomical structure or lumen resumes near normal to normal physiologic function. | 11-13-2014 |
20150018941 | METHODS AND APPARATUS FOR CONTROLLING THE INTERNAL CIRCUMFERENCE OF AN ANATOMIC ORIFICE OR LUMEN - An implantable device is provided for controlling shape and/or size of an anatomical structure or lumen. The implantable device has an adjustable member configured to adjust the dimensions of the implantable device. The implantable device is housed in a catheter and insertable from a minimally invasive surgical entry. An adjustment tool actuates the adjustable member and provide for adjustment before, during or after the anatomical structure or lumen resumes near normal to normal physiologic function. | 01-15-2015 |
James I. Fann, Ft. Lauderdale, FL US
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20110066231 | IMPLANTABLE DEVICES FOR CONTROLLING THE SIZE AND SHAPE OF AN ANATOMICAL STRUCTURE OR LUMEN - An implantable device system for controlling the dimensions of internal anatomic passages corrects physiologic dysfunctions resulting from a structural lumen which is either too large or too small. Implantable devices are disclosed which employ various mechanisms for adjusting and maintaining the size of an orifice to which they are attached. Systems permit the implants to be implanted using minimally invasive procedures and permit final adjustments to the dimensions of the implants after the resumption of normal flow of anatomic fluids in situ. | 03-17-2011 |
James I. Fann, Los Altos, CA US
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20110208295 | IMPLANTABLE DEVICES FOR CONTROLLING THE SIZE AND SHAPE OF AN ANATOMICAL STRUCTURE OR LUMEN - An implantable device system for controlling the dimensions of internal anatomic passages corrects physiologic dysfunctions resulting from a structural lumen which is either too large or too small. Implantable devices are disclosed which employ various mechanisms for adjusting and maintaining the size of an orifice to which they are attached. Systems permit the implants to be implanted using minimally invasive procedures and permit final adjustments to the dimensions of the implants after the resumption of normal flow of anatomic fluids in situ. | 08-25-2011 |
James I-Lin Fann, Portola Valley, CA US
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20090198322 | Methods And Apparatus For Cardiac Valve Repair - The methods, devices, and systems are provided for performing endovascular repair of atrioventricular and other cardiac valves in the heart. Regurgitation of an atrioventricular valve, particularly a mitral valve, can be repaired by modifying a tissue structure selected from the valve leaflets, the valve annulus, the valve chordae, and the papillary muscles. These structures may be modified by suturing, stapling, snaring, or shortening, using interventional tools which are introduced to a heart chamber. Preferably, the tissue structures will be temporarily modified prior to permanent modification. For example, opposed valve leaflets may be temporarily grasped and held into position prior to permanent attachment. | 08-06-2009 |
20100016958 | METHODS AND APPARATUS FOR CARDIAC VALVE REPAIR - The methods, devices, and systems are provided for performing endovascular repair of atrioventricular and other cardiac valves in the heart. Regurgitation of an atrioventricular valve, particularly a mitral valve, can be repaired by modifying a tissue structure selected from the valve leaflets, the valve annulus, the valve chordae, and the papillary muscles. These structures may be modified by suturing, stapling, snaring, or shortening, using interventional tools which are introduced to a heart chamber. Preferably, the tissue structures will be temporarily modified prior to permanent modification. For example, opposed valve leaflets may be temporarily grasped and held into position prior to permanent attachment. | 01-21-2010 |
20100217283 | LEAFLET SUTURING - The methods, devices, and systems are provided for performing endovascular repair of atrioventricular and other cardiac valves in the heart. Regurgitation of an atrioventricular valve, particularly a mitral valve, can be repaired by modifying a tissue structure selected from the valve leaflets, the valve annulus, the valve chordae, and the papillary muscles. These structures may be modified by suturing, stapling, snaring, or shortening, using interventional tools which are introduced to a heart chamber. Preferably, the tissue structures will be temporarily modified prior to permanent modification. For example, opposed valve leaflets may be temporarily grasped and held into position prior to permanent attachment. | 08-26-2010 |
John Fann, Shrewsbury, MA US
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20140329279 | COMPOSITIONS FOR CELL CULTURE AND METHODS OF USING THE SAME - Supplementation of the bioflavonoids such as epigallocatechin gallate, rutin, naringin, or genistein into mammalian cell culture media are shown to be effective in reduction of acidic species variants on recombinant antibodies. The demonstrated reduction in acidic species through the use of bioflavonoids, facilitates the manufacturing of a less heterogeneous product with potential improvements in antibody structure and function. | 11-06-2014 |
John C. Fann, Shrewsbury, MA US
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20080227136 | Cell culture improvements - The invention describes improved methods and compositions for producing a recombinant protein, e.g., an antibody, in mammalian cell culture. In addition, the invention provides improved cell culture media, including improved production media, feed solutions, and combination feeds, which may be used to improve protein productivity in mammalian cell culture. | 09-18-2008 |
20120077213 | CELL CULTURE IMPROVEMENTS - The invention describes improved methods and compositions for producing a recombinant protein, e.g., an antibody, in mammalian cell culture. In addition, the invention provides improved cell culture media, including improved production media, feed solutions, and combination feeds, which may be used to improve protein productivity in mammalian cell culture. | 03-29-2012 |
20120129727 | EFFICIENT AND EFFECTIVE SUPPLEMENT SCREENING FOR THE DEVELOPMENT OF CHEMICALLY DEFINED MEDIA IN CELL CULTURE - The present invention relates to methods of selecting and developing a chemically defined media (“CDM”) for use in the manufacture of biological products. In particular, the present invention is directed to screening methods to determine cell culture technique media supplement blends with enhanced performance characteristics. The present invention is also directed to identifying CDM supplement blends that demonstrate significant increases in harvest titer and/or viable cell density. | 05-24-2012 |
20140134674 | CELL CULTURE IMPROVEMENTS - The invention describes improved methods and compositions for producing a recombinant protein, e.g., an antibody, in mammalian cell culture. In addition, the invention provides improved cell culture media, including improved production media, feed solutions, and combination feeds, which may be used to improve protein productivity in mammalian cell culture. | 05-15-2014 |
20140134675 | CELL CULTURE IMPROVEMENTS - The invention describes improved methods and compositions for producing a recombinant protein, e.g., an antibody, in mammalian cell culture. In addition, the invention provides improved cell culture media, including improved production media, feed solutions, and combination feeds, which may be used to improve protein productivity in mammalian cell culture. | 05-15-2014 |
20140206038 | CELL CULTURE IMPROVEMENTS - The invention describes improved methods and compositions for producing a recombinant protein, e.g., an antibody, in mammalian cell culture. In addition, the invention provides improved cell culture media, including improved production media, feed solutions, and combination feeds, which may be used to improve protein productivity in mammalian cell culture. | 07-24-2014 |
20140234905 | CELL CULTURE IMPROVEMENTS - The invention describes improved methods and compositions for producing a recombinant protein, e.g., an antibody, in mammalian cell culture. In addition, the invention provides improved cell culture media, including improved production media, feed solutions, and combination feeds, which may be used to improve protein productivity in mammalian cell culture. | 08-21-2014 |
20150087024 | Cell Culture Improvements - The invention describes improved methods and compositions for producing a recombinant protein, e.g., an antibody, in mammalian cell culture. In addition, the invention provides improved cell culture media, including improved production media, feed solutions, and combination feeds, which may be used to improve protein productivity in mammalian cell culture. | 03-26-2015 |
John C. Fann, Shrewsbuury, MA US
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20140134675 | CELL CULTURE IMPROVEMENTS - The invention describes improved methods and compositions for producing a recombinant protein, e.g., an antibody, in mammalian cell culture. In addition, the invention provides improved cell culture media, including improved production media, feed solutions, and combination feeds, which may be used to improve protein productivity in mammalian cell culture. | 05-15-2014 |
Stephan Fann, Columbia, SC US
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20080299224 | Resuscitation fluid - The present invention relates to a resuscitation fluid which includes an ionic salt at a concentration above about 0.9%, at least one soluble protein, at least one intermediate energy substrate, and optionally an agent to mitigate intracellular acidosis. Methods of making and using the fluid are also described. | 12-04-2008 |
20100166885 | Resuscitation Fluid - The present invention relates to a resuscitation fluid which includes an ionic salt at a concentration above about 0.9%, at least one soluble protein, at least one intermediate energy substrate, and optionally an agent to mitigate intracellular acidosis. Methods of making and using the fluid are also described. | 07-01-2010 |
Steven Fann, West Hills, CA US
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20110048847 | NOISE ATTENUATION DEVICE FOR REDUCING NOISE ATTENUATION IN A JET ENGINE TEST CELL - A noise attenuation device for use in a jet engine test cell for testing a jet engine comprising a carbon steel pipe which is aligned axially with direction of exhaust from the jet engine. The carbon steel pipe is positioned within an augmenter within the test cell. Cold air enters the front end of the carbon-steel pipe. Adding three times the mass of cold air to that of the hot jet exhaust allows the hot jet exhaust to mix with the cold air forming an engine exhaust-cool air mixture. When the engine exhaust-cool air mixture reaches the outlet end of the carbon steel pipe, its temperature is reduced from 3800° F. to less than 1200° F., which substantially reduces noise generated by the jet exhaust. Located in proximity to the rear end of the carbon steel pipe is an annular region which is formed between perforated side plates within the carbon steel pipe and the inner wall of the augmenter. The flow is diffused as the flow area expands in the annular region. The combination of the carbon steel pipe and the annular region slow the velocity of the jet engine exhaust-cool air mixture, further reducing noise production from the jet engine. | 03-03-2011 |
Yaw Fann, San Jose, CA US
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20140181829 | PSEUDO-RANDOM HARDWARE RESOURCE ALLOCATION - Methods and apparatus for pseudo-random hardware resource allocation through a plurality of hardware elements. In an embodiment, resource list entries are configured to each identify one hardware element of the plurality of hardware elements. Index list entries are configured to each identify one resource list entry. An index list pointer is set to identify a first index list entry of the plurality of index list entries, and hardware resources are requested from a first hardware element of the plurality of hardware elements by identifying, using the index list pointer, the first index list entry; identifying, using the first index list entry, a first resource list entry; selecting the hardware element identified by the first resource list entry as the first hardware element; and sending a request for hardware resources to the first hardware element. | 06-26-2014 |