Verbruggen
Alfons Verbruggen, Wilsele BE
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20090274622 | NECROSIS AVID TRACER AGENT - The invention relates to a method for obtaining an image of ischemic, infarcted or necrotic tissue in a subject, comprising the step of administering an imaging agent comprising a phenanthro[1,10,9,8-opqra]perylene-7,14-dione compound. For example, the invention concerns to the use of phenanthro[1,10,9,8-opqra]perylene-7,14-dione derivatives, and more specifically hypericin or its derivatives, as necrosis or infarct specific agents. The phenanthro[1,10,9,8-opqra]perylene-7,14-dione derivatives can be labeled with a radionuclide, a radiopaque material or a material enhancing the effects magnetic resonance imaging. The invention further features a pharmaceutical composition comprising a phenanthro[1,10,9,8-opqra]perylene-7,14-dione compound optionally conjugated to a radionuclide or a radiopaque material, provided that said phenanthro[1,10,9,8-opqra]perylene-7,14-dione compound is not mono-[ | 11-05-2009 |
20110038795 | TARGETED RADIOTHERAPY - The present invention concerns a therapeutically labeled napthodianthrone or phenanthro[1,10,9,8-opqra]perylene-7,14-dione compound, which comprises a chemical element or an isotope that has an unstable nucleus and emits radiation during its decay to a stable form sufficient to destroy neighboring cells or tissues for use in a targeted radiotherapy to enhance curability of a warm-blooded animal that has been subjected to a necrosis-inducing antitumor therapy. A particular advantage of present invention is that viable rim resistant to a necrosis-inducing antitumor therapy such as vascular targeting agent (VTA) can be supplemented by one single or repeated doses of a therapeutically radiolabeled small molecule necrosis-avid chemical compound treatment to enhance the curability. Examples of necrosis inducing therapies are for instance minimally invasive tumor ablations applied chemically by percutaneous injection of ethanol or acetic acid, or physically by cryotherapy, microwave, focused ultrasound, interstitial laser therapy and radio-frequency ablation (RFA); by chemotherapies using cytotoxic agents or vascular targeting agents (VTA); and by external or internal radiotherapies. | 02-17-2011 |
Antonius Cornelius Verbruggen, Je Haarlem NL
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20080274868 | FOLDING CARD - A three ply folding card. A method of manufacturing folding cards involving folding two edge portions of a sheet over a central portion to superposition two or three plies of the folding card against each other. A blank for forming folding cards having a plurality of plies of the folding cards positioned on either side of a fold line, one or more of the plies, and its corresponding ply on the other side of the fold line being oriented differently to the other ply or plies. A sheet comprising a plurality of blanks or arrays of plies for forming folding cards. | 11-06-2008 |
August Verbruggen, Nazareth BE
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20110263948 | SCORING SYSTEM TO MONITOR NATURAL OR DRUG-MODIFIED DISEASE PROGRESSION IN "EROSIVE OSTEOARTHRITIS" OF THE INTERPHALANGEAL FINGER JOINTS - The present invention provides a scoring system to monitor natural or drug-modified disease progression in erosive inter-phalangeal finger joint osteoarthrits and the use of said scoring system to identify and value drugs with anticatabolic and/or repair promoting potential. | 10-27-2011 |
20110300562 | GDF15 AS A DIFFERENTIAL MARKER FOR SPONDYLOARTHROPATHY - In vitro methods for differential diagnosis of spondyloarthropathy are disclosed which involve determining the levels of GDF15 in biological samples. | 12-08-2011 |
August Verbruggen, Gent BE
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20100330036 | MARKERS OF MATRIX GENE EXPRESSION AND CELLULAR DIFFERENTIATION IN CHONDROCYTES - The invention relates generally to the field of tissue engineering. More particularly, the present invention relates to methods for identifying a population of cells suitable for the repair of connective tissue, including cartilage. The invention further provides methods and compositions related to the generation of a population of cells suitable for the repair of cartilage, in particular in the repair of cartilage degeneration associated with osteoarthritis. Methods of using said cells thus identified or thus generated, in methods to extend the period of cell manipulation, i.e. to increase the yield of cells suitable in the aforementioned methods, are also provided by the present invention. | 12-30-2010 |
August Lodewijk Verbruggen, Nazareth-Eke BE
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20110172182 | Carboxyethylated Cyclodextrin Polysulfates Useful As Medicaments - This invention relates to novel β-cyclodextrin polysulfate compounds comprising from one to three 2-carboxyethyl substituents, and at least two sulfates groups per glucopyranose unit, which are useful as active ingredients for the treatment and/or prophylaxis of degenerative joint diseases, osteoarthritis, articular rheumatism, arthrosis or degenerative arthritis, or for the treatment of heparin-induced thrombocytopenia, or for cartilage repair or connective tissue repair. | 07-14-2011 |
Bob Verbruggen, Kessel-Lo BE
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20100328120 | Comparator Based Asynchronous Binary Search A/D Conveter - The present invention is related to an analog-to-digital converter circuit ( | 12-30-2010 |
20120133535 | Interleaved Pipelined Binary Search A/D Converter - The present invention is related to a pipelined analog-to-digital converter, ADC, for converting an analog input signal into a digital signal comprising—a plurality of comparing means having tuneable thresholds for comparing an input signal with; at least two of said given thresholds being different and—a plurality of amplifying circuits,—wherein said plurality of comparing means is configured to form a hierarchical tree structure, said hierarchical tree structure having a plurality of hierarchical levels, wherein at least one of said hierarchical levels is associated with at least one amplifying circuit of said plurality of amplifying circuits, said at least one amplifying circuit generating the input of at least one comparing means at the next hierarchical level and—wherein said plurality of hierarchical levels comprises means for setting said tuneable thresholds in accordance to the output of previous hierarchical level so that non-linear distortion of the preceding hierarchical level is removed. | 05-31-2012 |
20130015988 | Stochastic Analog-to-Digital (A/D) Converter And Method For Using The SameAANM Verbruggen; BobAACI Kessel-LoAACO BEAAGP Verbruggen; Bob Kessel-Lo BEAANM Craninckx; JanAACI BoutersemAACO BEAAGP Craninckx; Jan Boutersem BE - An analog-to-digital (A/D) converter circuit arranged for receiving an analog input signal and for outputting a digital representation of said analog input signal is described. The A/D converter circuit includes: | 01-17-2013 |
20130214946 | A/D Converter and Method for Calibrating the Same - An ADC includes sampling means for sampling an input voltage signal, comparator(s) for receiving the sampled signal, and a DAC including circuitry for generating a search signal approximating the input signal and a calibration signal. The search signal and the calibration signal are to be applied to a comparator. The ADC also includes a search logic block for receiving a comparator output signal, for providing input to the DAC for generating the search signal, and for producing a digital output signal. Further, the ADC includes a calibration logic block for producing a control signal to control the circuitry of the DAC and including processing means for observing the output signal, for comparing the output signal with a desired output, and for compensating analogue non-idealities of the ADC. The DAC circuitry is adapted for generating the calibration signal in accordance with the control signal and with the sampled input signal. | 08-22-2013 |
20160027528 | Sample-and-Hold Circuit for an Interleaved Analog-to-Digital Converter - The present disclosure relates to a sample-and-hold circuit includes a transistor arranged for switching between a sample mode and a hold mode and a bootstrap circuit arranged for maintaining in the sample mode a voltage level between a source terminal and a gate terminal of the transistor independent of the voltage at the source terminal and arranged for switching off the transistor in the hold mode. The bootstrap circuit includes a bootstrap capacitance arranged for being precharged to a given voltage during the hold mode, the bootstrap capacitance being connected between the source terminal and the gate terminal during the sample mode. In one example, the bootstrap circuit comprises a switched capacitor charge pump for generating the given voltage. | 01-28-2016 |
Maria Anna Verbruggen, Renkum NL
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20090252792 | METHOD TO REDUCE THE SYMPTOMS OF HEARTBURN AND GASTRO-OESOPHAGEAL REFLUX DISEASE (GERD) BY SPECIFIC POLYSACCHARIDES - The invention is directed to the use of a specific group of polysaccharides for reducing the symptoms or heartburn and gastroesophageal reflux isease. In addition, a pharmaceutical preparation is provided comprising a specific group of polysaccharides having a high hydration rate, a high viscosity, and a high stability at low pH. Such a preparation is particularly effective in reducing the symptoms of heartburn and/or gastro-oesophageal reflux disease, particularly when consumed in dry form. | 10-08-2009 |
20120231078 | METHOD TO REDUCE THE SYMPTOMS OF HEARTBURN AND GASTRO-OESOPHAGEAL REFLUX DISEASE (GERD) BY SPECIFIC POLYSACCHARIDES - The invention is directed to the use of a specific group of polysaccharides for reducing the symptoms of heartburn and gastroesophageal reflux isease. In addition, a pharmaceutical preparation is provided comprising a specific group of polysaccharides having a high hydration rate, a high viscosity, and a high stability at low pH. Such a preparation is particularly effective in reducing the symptoms of heartburn and/or gastro-oesophageal reflux disease, particularly when consumed in dry form. | 09-13-2012 |
Maria Anna Verbruggen, Dh Renkum NL
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20150290271 | Nutraceutical Composition Obtained from Fungus-Challenged Soy Seedlings - Soybean seedlings and therefrom extractable compositions are described. Such compositions comprise prenylated isoflavones and at least one isoflavonoid, said isoflavonoid being selected from one of the chemical classes of isoflavones, coumestans and pterocarpans. Such compositions usually comprise at least 5% prenylated isoflavones, in particular prenylated isoflavones selected from prenylated daidzein, prenylated hydroxydaidzein, prenylated glycitein, prenylated hydroxygenistein, and prenylated genistein. Such compositions also comprise pterocarpans, preferably in amounts of at least 20%, and with a novel ratio of glyceollin I to glyceollin II to glyceollin III to glyceollin IV. Also described is a production method comprising the step of fermenting the soybeans under stress, in particular in the presence of cultures of fungi, preferably in the presence of | 10-15-2015 |
Marioes Verbruggen, Endhoven NL
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20110186774 | PROCESSES FOR PREPARING SULPHUR COMPOSITES AND ORGANOSILANE COUPLING AGENTS - A process for preparing sulphur composites is disclosed. Molten sulphur is combined with filler and/or aggregate, with a compound of formula (I) wherein R | 08-04-2011 |
Nathalie Verbruggen, Ixelles BE
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20090138984 | Genes involved in tolerance to environmental stress - The present invention relates to a method for obtaining polynucleic acids comprising coding sequences and/or genes involved in environmental stress resistance in plants, comprising the preparation of a cDNA library comprising coding sequences from siliques, introducing said coding sequences in yeast cells in a functional format and screening for polynucleic acids leading to an enhanced tolerance or resistance to environmental stress conditions in said transformed yeast cells. The present invention further relates to an isolated polynucleic acid obtainable by such a method as listed in Table 1 as well as recombinant polynucleic acid comprising the same. The present invention further relates to an isolated polypeptide encoded by a polynucleic acid of the invention. The present invention also relates to a method for producing a plant with enhanced tolerance or resistance to environmental stress, said method comprising introducing into a plant cell a recombinant DNA comprising a polynucleic acid as defined which when expressed in a plant cell enhances the tolerances or induces resistance to environmental stress conditions of said plant. The present invention particularly relates to plant cells, plants or harvestable parts or propagation material thereof transformed with a recombinant polynucleic acid as defined above. | 05-28-2009 |
20130291220 | Genes Involved in Tolerance to Environmental Stress - The present invention relates to a method for obtaining polynucleic acids comprising coding sequences and/or genes involved in environmental stress resistance in plants, comprising preparing a cDNA library comprising coding sequences from siliques, introducing the coding sequences in yeast cells in a functional format and screening for polynucleic acids leading to an enhanced tolerance or resistance to environmental stress conditions in the transformed yeast cells. The present invention further relates to an isolated polynucleic acid obtainable by such a method as listed in Table 1 as well as recombinant polynucleic acid comprising the same. The present invention further relates to an isolated polypeptide encoded by a polynucleic acid of the invention. The present invention also relates to a method for producing a plant with enhanced tolerance or resistance to environmental stress comprising introducing into a plant cell a recombinant DNA comprising a polynucleic acid as defined which when expressed in a plant cell enhances the tolerances or induces resistance to environmental stress conditions of the plant. The present invention particularly relates to plant cells, plants or harvestable parts or propagation material thereof transformed with a recombinant polynucleic acid as defined above. | 10-31-2013 |
Patrick Verbruggen, Orbais BE
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20130270451 | Magnetic Structure For Circular Ion Accelerator - A magnet structure for use in a circular ion accelerator, such as e.g. a synchrocyclotron comprises a cold-mass structure including superconducting magnetic coils ( | 10-17-2013 |
Patrick Verbruggen, Orbaix BE
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20140320044 | RF SYSTEM FOR SYNCHROCYCLOTRON - The present invention relates to an RF system ( | 10-30-2014 |
Paul Verbruggen, Helmond NL
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20150245643 | COMBINATION OF COOKING AND SMOKING - The present invention relates to an oven comprising: a first chamber ( | 09-03-2015 |
Paul Verbruggen, Md Helmond NL
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20150342227 | COMBINATION OF DRYING AND SMOKING - The present invention relates to a line comprising an oven and a drying chamber. The present invention further relates to a process how to cook s food product. | 12-03-2015 |
Rudi Verbruggen US
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20160047999 | MOVEABLE BEND CONTROL AND PATCH CORD SUPPORT FOR TELECOMMUNICATIONS PANEL - A termination field and a guide member are independently pivotally coupled to a base body. The termination field pivots relative to the base body along a path of travel. The guide member is coupled to the base body to provide bend radius protection to cables plugged into the termination field. The guide member defines a channel leading the cables from the termination field towards a first side of the base body at an exterior of the base body. In certain examples, the guide member and termination field pivot relative to the base body about different hinge axes. In other examples, the termination field pivots with the guide member for part of the path of travel and relative to the guide member for another part of the path of travel. | 02-18-2016 |
Rudi Verbruggen, Holsbeek BE
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20160047999 | MOVEABLE BEND CONTROL AND PATCH CORD SUPPORT FOR TELECOMMUNICATIONS PANEL - A termination field and a guide member are independently pivotally coupled to a base body. The termination field pivots relative to the base body along a path of travel. The guide member is coupled to the base body to provide bend radius protection to cables plugged into the termination field. The guide member defines a channel leading the cables from the termination field towards a first side of the base body at an exterior of the base body. In certain examples, the guide member and termination field pivot relative to the base body about different hinge axes. In other examples, the termination field pivots with the guide member for part of the path of travel and relative to the guide member for another part of the path of travel. | 02-18-2016 |
Timotheus Wilhelmus Verbruggen, Petten NL
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20120011917 | DEVICE AND METHOD FOR MEASURING STRAIN - A device for measuring strain on a surface of an object ( | 01-19-2012 |