Donald, GB
Alastair Donald, Abingdon GB
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20090247538 | Ortho-Condensed Pyridine and Pyrimidine Derivatives (e.g., Purines) as Protein Kinases Inhibitors - The invention provides a compound for use as a protein kinase B inhibitor, the compound being a compound of the formula (I) or salts, solvates, tautomers or N-oxides thereof, wherein T is N or CR | 10-01-2009 |
Alastair Donald, Oxfordshire GB
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20090099213 | Ortho-Condensed Pyridine and Pyrimidine Derivatives (e.g., Purines) as Protein Kinases Inhibitors - The invention provides a compound for use in the prophylaxis or treatment of a disease state or condition mediated by protein kinase B, the compound having the formula (I): or salts, solvates, tautomers or N-oxides thereof, wherein T is N or CR | 04-16-2009 |
20140303177 | ORTHO-CONDENSED PYRIDINE AND PYRIMIDINE DERIVATIVES (E.G., PURINES) AS PROTEIN KINASES INHIBITORS - The invention provides a compound for use as a protein kinase B inhibitor, the compound being a compound of the formula (I) or salts, solvates, tautomers or N-oxides thereof, wherein T is N or CR | 10-09-2014 |
Alastair David Graham Donald, Abingdon GB
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20120149736 | ENZYME INHIBITORS - Compounds of formula (I), inhibit HDAC activity: wherein A, B and D independently represent ═CH— or ═N—; W is —CH═CH— Or —CH | 06-14-2012 |
Alastair David Graham Donald, Oxfordshire GB
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20100010010 | HDAC INHIBITORS - Compounds of formula (I) inhibit HDAC activity, wherein A, B and D independently represent ═C— or ═N—; W is a divalent radical —CH═CH— or CH | 01-14-2010 |
20130143926 | BENZAMIDE DERIVATIVES AND THEIR USE AS HSP90 INHIBTORS - The invention provides a compound which is (a) a phenylamide derivative of formula (I) or a tautomer thereof, or (b) a pharmaceutically acceptable salt, N-oxide, hydrate, prodrug or solvate thereof: wherein R | 06-06-2013 |
20130303576 | ENZYME INHIBITORS - Compounds of formula (I), inhibit HDAC activity: wherein A, B and D independently represent ═CH— or ═N—; W is —CH═CH—Or —CH | 11-14-2013 |
20140155439 | ENZYME INHIBITORS - Compounds of formula (I), inhibit HDAC activity: wherein A, B and D independently represent ═CH— or ═N—; W is —CH═CH— Or —CH | 06-05-2014 |
20140163042 | ENZYME INHIBITORS - Compounds of formula (I) are inhibitors of histone deacetylase activity, and are useful in the treatment of, for example, cancers, wherein R | 06-12-2014 |
20140323531 | HDAC INHIBITORS - Compounds of formula (I) inhibit HDAC activity: | 10-30-2014 |
Alastair David Grahm Donald, Oxfordshire GB
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20130197042 | HDAC INHIBITORS - Compounds of formula (I) inhibit HDAC activity: | 08-01-2013 |
Alistair Donald, Oxfordshire GB
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20140107137 | Ortho-Condensed Pyridine and Pyrimidine Derivatives (e.g., Purines) as Protein Kinases Inhibitors - The invention provides a compound for use as a protein kinase B inhibitor, the compound being a compound of the formula (I) or salts, solvates, tautomers or N-oxides thereof, wherein T is N or CR | 04-17-2014 |
Alistair David Graham Donald, Oxfordshire GB
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20090291978 | Enzyme Inhibitors - Compounds of formula (I) are inhibitors of histone deacetylase activity, and are useful in the treatment of, for example, cancers, wherein R | 11-26-2009 |
20100317678 | HYDROXAMATES AS INHIBITORS OF HISTONE DEACETYLASE - Compounds of formula (I), and salts, N-oxides, hydrates and solvates thereof are histone deacetylase inhibitors and are useful in the treatment of cell proliferative diseases, including cancers: | 12-16-2010 |
20100317865 | ENZYME AND RECEPTOR MODULATION - Covalent conjugates of an α,α-disubstituted glycine ester and a modulator of the activity of a target intracellular enzyme or receptor, wherein the ester group of the conjugate is hydrolysable by one or more intracellular carboxylesterase enzymes to the corresponding acid and the α,α-disubstituted glycine ester is conjugated to the modulator at a position remote from the binding interface between the inhibitor and the target enzyme or receptor pass into cells and the active acid hydrolysis product accumulates within the cells. | 12-16-2010 |
Alistair David Graham Donald, Abingdon GB
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20130116318 | Enzyme Inhibitors - Compounds of formula (I) are inhibitors of histone deacetylase activity, and are useful in the treatment of, for example, cancers: | 05-09-2013 |
Alistair Ross Donald, Somerset GB
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20100186964 | Connection device - A connection device comprises a lock component of non-circular cross-sectional shape, the lock component being both angularly and axially moveable relative to a housing, stop means operable to limit angular movement of the lock component relative to the housing, the lock component having a threaded drive region, and a drive nut in threaded engagement with the drive region, wherein angular movement of the drive nut relative to the housing when the stop means are not engaged is able to drive the lock component for angular movement, rotation of the drive nut when the stop means are engaged causing axial displacement of the lock component relative to the housing. | 07-29-2010 |
Barrow-Williams Timothy Donald, St. Albans GB
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20120065593 | Injection Device - An injection device | 03-15-2012 |
Craig Samuel Donald, Macclesfield GB
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20100317653 | OXADIAZOLE DERIVATIVES AS DGAT INHIBITORS - Compounds of formula (I), and salts and pro-drugs thereof: | 12-16-2010 |
20140357661 | CHEMICAL COMPOUNDS - The invention concerns compounds of Formula (I) | 12-04-2014 |
David Donald, Leicestershire GB
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20090042942 | Muscarinic Receptor Antagonists - The invention provides compounds of formula (I), wherein R | 02-12-2009 |
Ian Donald, Monymusk GB
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20150075805 | OILFIELD APPARATUS AND METHODS OF USE - The invention in one of its aspects provides a connection apparatus for a subsea hydraulic circuit and method of use in a sampling application. The apparatus comprises a longitudinal body configured to be removably docked with a subsea hydraulic circuit receptacle. The body comprises a plurality of radial ports axially displaced along the body, and an axial bore accommodating a spool having at least one fluid barrier. The spool and fluid barrier are actuable to be axially moved in the bore to control axial flow paths along the bore between the plurality of radial ports. The apparatus may be configured as a sampling hot stab in an application to sampling a production fluid from a subsea hydrocarbon production system. | 03-19-2015 |
20150114658 | OILFIELD APPARATUS AND METHODS OF USE - The invention provides a flow control valve for a subsea hydrocarbon production system and a method of use. The flow control valve comprises an inlet configured to be in fluid communication to an injection fluid conduit and an outlet configured to be in fluid communication with a subsea flow system. A flow control mechanism is disposed in a flow path between the inlet and the outlet and is arranged to adjust a flow rate through the flow path. The flow control mechanism is configured to automatically adjust the flow rate of injection fluid through the flow path according to a pressure differential between fluid pressure at the inlet and fluid pressure at the outlet. Adjustment may be self-regulating, or may be controlled by a hydraulic control circuit. | 04-30-2015 |
20150184511 | Well Testing and Production Apparatus and Method - A well testing device for conducting well test operations on an oil, gas, or water well including a production flowline. A conduit guides fluids from the production flowline to the well test device and then back to the flowline. The well test device may include, in various combinations, one or more of a flow measurement device, a sampling device, a sampling chamber to collect sampled fluids from the production flowline, a particle separator, a particle detector, a pressure sensor, a temperature sensor, a controller or data storage module, a choke, and other components. | 07-02-2015 |
Ian Donald, Inverurie, Aberdeenshire GB
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20150114658 | OILFIELD APPARATUS AND METHODS OF USE - The invention provides a flow control valve for a subsea hydrocarbon production system and a method of use. The flow control valve comprises an inlet configured to be in fluid communication to an injection fluid conduit and an outlet configured to be in fluid communication with a subsea flow system. A flow control mechanism is disposed in a flow path between the inlet and the outlet and is arranged to adjust a flow rate through the flow path. The flow control mechanism is configured to automatically adjust the flow rate of injection fluid through the flow path according to a pressure differential between fluid pressure at the inlet and fluid pressure at the outlet. Adjustment may be self-regulating, or may be controlled by a hydraulic control circuit. | 04-30-2015 |
Ian Donald, Aberdeen GB
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20150292291 | Method and Apparatus for Oil and Gas Operations - An apparatus and system for accessing a flow system (such as a subsea tree) in a subsea oil and gas production system, and method of use. The apparatus comprises a body defining a conduit therethrough and a first connector for connecting the body to the flow system. A second connector is configured for connecting the body to an intervention apparatus, such as an injection or sampling equipment. In use, the conduit provides an intervention path from the intervention apparatus to the flow system. Aspects of the invention relate to combined injection and sampling units, and have particular application to well scale squeeze operations. | 10-15-2015 |
Malcolm Roger Curzon Donald, Dumfreisshire GB
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20110179746 | Flooring element - A method of making a flooring element. The flooring element is a tile formed of a polymer with embedded filler material. The filler material includes abrasive particles adjacent the top surface and a resilient or rubber-like material. The bottom surface of the tile includes a plurality of particles embedded in and extending from the bottom, which enables the tile to be securely adhered to a substrate. One embodiment of a method of making the tile includes adding a first layer containing a filler material to a mold, vibrating the mold to cause the heavier filler material to sink, applying a plurality of particles to the top of the polymer mixture in the mold, and polymerizing the mixture in the mold. In another embodiment, a second layer including resilient particles is added to the mold above the first layer before the mold is vibrated. | 07-28-2011 |
Trevor L. Donald, Buckinghamshire GB
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20120238921 | DIFFERENTIAL AIR PRESSURE SYSTEMS AND METHODS OF USING AND CALIBRATING SUCH SYSTEMS FOR MOBILITY IMPAIRED USERS - Described herein are various embodiments of differential air pressure systems and methods of using and calibration such systems for individuals with impaired mobility. The differential air pressure systems may comprise an access assist device configured to help a mobility impaired user to stand in a pressure chamber configured to apply a positive pressure on a portion of the user's body in the seals pressure chamber. The system may further comprise load sensors configured to measure the user's weight exerted inside and outside the chamber. The system may be calibrated by determining a relationship between the actual weight of the user and the pressure in the chamber, where the actual weight of the user may be measured by more than one load sensor and at least one load sensor is not in the chamber. | 09-20-2012 |