Sim, US
B. Kim Lee Sim, Gaithersburg, MD US
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20100183680 | Purified Plasmodium and Vaccine Compositions - Disclosed are substantially purified | 07-22-2010 |
20120058543 | Purified Plasmodium and Vaccine Compositions - Disclosed are substantially purified | 03-08-2012 |
20130224250 | Purified Plasmodium and Vaccine Composition - Disclosed are substantially purified | 08-29-2013 |
20130251750 | Purified Plasmodium and Vaccine Composition - Disclosed are substantially purified | 09-26-2013 |
20150313981 | Purified Plasmodium and Vaccine Compositions - Disclosed are substantially purified | 11-05-2015 |
Daniel T. Sim, Everett, WA US
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20110276217 | Hard Landing Report Based on Sink Rate Algorithm - A system and a method for detecting a hard landing or other high load event of an aircraft and then automatically triggering a report of such hard landing event. A sink rate algorithm is used to estimate the altitude rate of a main gear. The sink rate algorithm uses a plurality of flight parameters to estimate the main gear altitude rate, preferably including at least the following: pitch altitude, radio altitude, vertical acceleration, body pitch rate and vertical speed. This invention has the potential to reduce the number of unnecessary structural inspections, and may also limit the scope of any such required inspections. | 11-10-2011 |
David Y. Sim, Media, PA US
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20120305316 | EARTH DRILLING APPARATUS AND METHOD - Well drilling and well casing placement are carried out by a process in which a drill string and surrounding casing are advanced while being rotated, preferably in opposite directions. The process is preferably carried out using a drill rig having a mast that is movable along its direction of elongation and a casing rotation table fixed to the mast. | 12-06-2012 |
20150275595 | DRILL PIPE HANDLING APPARATUS HAVING IMPROVED PIPE GRIPPING MECHANISM - In a drill pipe handling apparatus, a pipe gripping mechanism comprises three pipe-gripping jaws arranged to grip a pipe at locations adjacent the apices of a triangle containing the axis of the pipe. A first pipe gripping jaw is connectible to a first pivoted arm at any selected one of plural distances from the pivot axis of the first arm and connected to the first arm at one of those plural distances, and a second jaw is connectible to the second arm at any selected one of said plural distances from the pivot axis of the second arm and connected to said second arm at said one of said plural distances. Because the same first and second jaws are connectible to the arms at plural distances from the pivot axes, the same jaws can accommodate a wide range of pipe diameters. | 10-01-2015 |
Dong-Gyu Sim, Bellevue, WA US
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20110301464 | HOME ULTRASOUND SYSTEM - In embodiments of the present invention, an ultrasound system includes an ultrasound machine, which may be located in a hospital, clinic, vehicle, home, etc., coupled to a remotely located diagnosis station via a communication network. For some embodiments, the ultrasound machine includes an application-specific scan head that has identification information that allows the home ultrasound machine to notify a user whether the attached scan head is appropriate for the type of examination to be performed. For other embodiments, a first stage of beamforming is conducted in reconfigurable hardware and a second stage of beamforming is conducted in programmable software digital signal processor. The diagnosis station may transfer information associated with a scanning protocol for the ultrasound examination to the ultrasound machine via the communication network, and the ultrasound machine may transfer measurement values acquired during the ultrasound examination to the diagnosis station via the communication network. | 12-08-2011 |
Francis Sim, Allentown, PA US
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20110192753 | SHAPABLE RESIN COMPOSITIONS - The present invention provides processes for the extrusion of a shapable resin-containing composition as a foam, wherein said composition comprises at least one extrudable resin and at least one saccharide ester of Formula I: | 08-11-2011 |
20110196072 | SHAPABLE RESIN COMPOSITIONS - The present invention provides processes for the extrusion of a shapeable resin-containing composition as a foam, wherein said composition comprises at least one extrudable resin and at least one saccharide ester of Formula I: | 08-11-2011 |
Fraser Sim, Batavia, NY US
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20110002846 | CD24 AS A BRAIN TUMOR STEM CELL MARKER AND A DIAGNOSTIC AND THERAPEUTIC TARGET IN PRIMARY NEURAL AND GLIAL TUMORS OF THE BRAIN - The present invention is directed to methods of treating a primary brain tumor and preventing the migratory spread of a primary brain tumor in a subject. These methods involve utilizing the CD24 surface protein selectively expressed on tumor progenitor cells as a therapeutic target as well as a means for directing oncolytic therapeutics directly to the tumor site. The present invention further relates to methods of diagnosing the presence of a brain tumor and monitoring the status of the brain tumor in a subject based on CD24 expression in tumor progenitor cells. | 01-06-2011 |
20150216875 | MODULATING THE PRODUCTION OF NEURONS AND/OR OLIGODENDROCYTES FROM WHITE MATTER PROGENITOR CELLS - The present invention relates to a method of modulating production of neurons and/or oligodendrocytes from neural progenitor cells of human white matter and to a method of treating a subject for a condition modulated by underproduction of oligodendrocytes from human white matter. Both of these methods involve administering an agonist or antagonist of one or more molecules set forth in Tables 1 and/or 2 to the neural progenitor cells. Also disclosed is a method of using an inhibitor of sterol synthesis to differentiate oligodendrocyte progenitor cells to oligodendrocytes. | 08-06-2015 |
Fraser J. Sim, Buffalo, NY US
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20110059055 | TREATING MYELIN DISEASES WITH OPTIMIZED CELL PREPARATIONS - The disclosure relates to oligodendrocyte-biased glial progenitor cells and methods of making, isolating, and using such cells. | 03-10-2011 |
Fraser James Sim, Batavia, NY US
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20090148431 | MODULATING THE PRODUCTION OF NEURONS AND/OR OLIGODENDROCYTES FROM WHITE MATTER PROGENITOR CELLS - The present invention relates to a method of modulating production of neurons and/or oligodendrocytes from neural progenitor cells of human white matter and to a method of treating a subject for a condition modulated by underproduction of oligodendrocytes from human white matter. Both of these methods involve administering an agonist or antagonist of one or more molecules set forth in Tables 1 and/or 2 to the neural progenitor cells. Also disclosed is a method of using an inhibitor of sterol synthesis to differentiate oligodendrocyte progenitor cells to oligodendrocytes. | 06-11-2009 |
Gordon Sim, Sandy, UT US
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20090181520 | Method and Structure for Dividing a Substrate into Individual Devices - A method for obtaining individual dies from a semiconductor structure is disclosed. The semiconductor structure includes a device layer, and the device layer in turn includes active regions separated by predefined spacings. Thick metal is selectively formed on backside of the device layer such that thick metal is formed on backside of active regions but not on backside of the predefined spacings. The semiconductor structure is then cut along the predefined spacings to separate the active regions with thick metal on their backside into individual dies. | 07-16-2009 |
20110201179 | METHOD AND STRUCTURE FOR DIVIDING A SUBSTRATE INTO INDIVIDUAL DEVICES - A method for obtaining individual dies from a semiconductor structure is disclosed. The semiconductor structure includes a device layer, and the device layer in turn includes active regions separated by predefined spacings. Thick metal is selectively formed on backside of the device layer such that thick metal is formed on backside of active regions but not on backside of the predefined spacings. The semiconductor structure is then cut along the predefined spacings to separate the active regions with thick metal on their backside into individual dies. | 08-18-2011 |
Hak C. Sim, Painted Post, NY US
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20120212748 | OPTICAL READER SYSTEMS AND METHODS FOR MICROPLATE POSITION DETECTION - Optical reader systems and methods with accurate microplate position detection capability are disclosed. The optical reader systems having scanning optical systems that are configured to scan select position-detecting features on the microplate to accurately determine their respective positions. The measurement of the positions of the position-detecting features can also be used to calibrate the optical reader system to reduce or eliminate adverse positioning effects from system non-linearities that arise from one or more of the system components, including the scanning optical system. | 08-23-2012 |
Hak Chuah Sim, Painted Post, NY US
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20130100462 | Optical Reader Systems And Methods With Rapid Microplate Position Detection - Optical reader systems and methods with rapid microplate position detection capability are disclosed. The optical reader system includes a scanning optical system configured to scan select position-detecting features to accurately determine the microplate position within the optical reader system. The method includes measuring positions of the position-detecting features in order of their respective amounts of position tolerance, from smallest to largest. The position measurement is carried out for a number of position-detecting features sufficient to determine the microplate position with the optical reader system to within a select microplate position tolerance. | 04-25-2013 |
Hak Chuah Sim, Dallas, TX US
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20080204756 | EDGE NORMAL PROCESS - An edge inspection method for detecting defects on a wafer edge normal surface includes acquiring a set of digital images which captures a circumference of the wafer. An edge of the wafer about the circumference is determined. Each digital image is segmented into a plurality of horizontal bands. Adjacent edge clusters about the circumference of the wafer are combined into edge pixel bins. The edge pixel bins are analyzed via edge clusters analysis to identify defects. The edge pixel bins are also analyzed via blob analysis to determine defects. | 08-28-2008 |
Henry Sim, Kaneohe, HI US
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20100140574 | Adjustable Automotive Suspension Tool - An automotive tool serving as a pinch bar and lever for gripping an automotive suspension workpiece between first and second tool elements and an extended handle for increasing force to free the workpiece from its fastened position. Alternately, the first and second tool elements can be positioned against opposing workpieces to free one from the other again using the extended handle to amplify the applied force causing separation. The tool is designed for the automotive repair industry in the removal and installation of suspension members, such as CV joints, ball joints, struts, etc that require the dismantling of parts that have bonded due to dirt, wear and electrolytic reactions, such as oxidation, resulting in time intensive and hazardous tasks depending on the inventiveness of the mechanic in performing the separation task. | 06-10-2010 |
H. Jin Sim, Raleigh, NC US
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20120202059 | DRY TYPE ELECTRICAL INSULATION - A dry type electrical insulation is provided. The insulation includes a base fiber having an outer surface and a first melting point and a binder material, coated onto the outer surface of the base fiber, having a second melting point. In this insulation, the second melting point is lower than the first melting point. A dry type insulation matrix is also provided. The insulation matrix includes a plurality of composite fibers having a base fiber having a first melting point and a binder material co-extruded therewith, having a second melting point. In this insulation matrix, the second melting point is lower than the first. | 08-09-2012 |
Jae Sim, Upper Darby, PA US
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20130218838 | MOVEABLE STORAGE - A mobile storage system is disclosed that in one aspect identifies a geographical location change of a user, such as movement from a first geographical location to a second geographical location. In response, the mobile storage system may move the user's information to a storage device associated with the second geographical location so that the user's information may be accessed by the user more efficiently. | 08-22-2013 |
20130308470 | Wireless Network Supporting Extended Coverage of Service - A communications access point may provide access to a wireless communications network to a user device located at a first location. The communications access point may determine that the user device is moving from the first location to a second location where access to the wireless network is limited or not available. In response to the determination, the communications access point may provide access to the wireless network at the second location by extending a coverage area of the wireless network. | 11-21-2013 |
20140297582 | Movable Storage - A mobile storage system is disclosed that in one aspect identifies a geographical location change of a user, such as movement from a first geographical location to a second geographical location. In response, the mobile storage system may move the user's information to a storage device associated with the second geographical location so that the user's information may be accessed by the user more efficiently. | 10-02-2014 |
Jae Auk Sim, Deerfield, IL US
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20100050331 | System and method for flushing a toilet - A system and method is provided for flushing a toilet wherein the duration of the flush, and thus the amount of water used, is selectable by a user. In an embodiment, the system includes a controller and a non-buoyant flush valve that are coupled together via a linkage. The controller opens the flush valve for a time period set by a user. Once the time period has lapsed, the flush valve is closed. | 03-04-2010 |
Jaewoong Sim, Atlanta, GA US
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20140143493 | Bypassing a Cache when Handling Memory Requests - The described embodiments include a computing device that handles memory requests. In some embodiments, when a memory request is to be sent to a cache in the computing device or to be bypassed to a next lower level of a memory hierarchy in the computing device based on expected memory request resolution times, a bypass mechanism is configured to send the memory request to the cache or bypass the memory request to the next lower level of the memory hierarchy. | 05-22-2014 |
20140143502 | Predicting Outcomes for Memory Requests in a Cache Memory - The described embodiments include a cache controller with a prediction mechanism in a cache. In the described embodiments, the prediction mechanism is configured to perform a lookup in each table in a hierarchy of lookup tables in parallel to determine if a memory request is predicted to be a hit in the cache, each table in the hierarchy comprising predictions whether memory requests to corresponding regions of a main memory will hit the cache, the corresponding regions of the main memory being smaller for tables lower in the hierarchy. | 05-22-2014 |
20140143505 | Dynamically Configuring Regions of a Main Memory in a Write-Back Mode or a Write-Through Mode - The described embodiments include a main memory and a cache memory (or “cache”) with a cache controller that includes a mode-setting mechanism. In some embodiments, the mode-setting mechanism is configured to dynamically determine an access pattern for the main memory. Based on the determined access pattern, the mode-setting mechanism configures at least one region of the main memory in a write-back mode and configures other regions of the main memory in a write-through mode. In these embodiments, when performing a write operation in the cache memory, the cache controller determines whether a region in the main memory where the cache block is from is configured in the write-back mode or the write-through mode and then performs a corresponding write operation in the cache memory | 05-22-2014 |
20140164713 | Bypassing Memory Requests to a Main Memory - Some embodiments include a computing device with a control circuit that handles memory requests. The control circuit checks one or more conditions to determine when a memory request should be bypassed to a main memory instead of sending the memory request to a cache memory. When the memory request should be bypassed to a main memory, the control circuit sends the memory request to the main memory. Otherwise, the control circuit sends the memory request to the cache memory. | 06-12-2014 |
20140173211 | Partitioning Caches for Sub-Entities in Computing Devices - Some embodiments include a partitioning mechanism that partitions a cache memory into sub-partitions for sub-entities. In the described embodiments, the cache memory is initially partitioned into two or more partitions for one or more corresponding entities. During a partitioning operation, the partitioning mechanism is configured to partition one or more of the partitions in the cache memory into two or more sub-partitions for one or more sub-entities of a corresponding entity. A cache controller then uses a corresponding sub-partition for memory accesses by the one or more sub-entities. | 06-19-2014 |
20140173379 | DIRTY CACHELINE DUPLICATION - A method of managing memory includes installing a first cacheline at a first location in a cache memory and receiving a write request. In response to the write request, the first cacheline is modified in accordance with the write request and marked as dirty. Also in response to the write request, a second cacheline is installed that duplicates the first cacheline, as modified in accordance with the write request, at a second location in the cache memory. | 06-19-2014 |
20140181384 | Memory Scheduling for RAM Caches Based on Tag Caching - A system, method and computer program product to store tag blocks in a tag buffer in order to provide early row-buffer miss detection, early page closing, and reductions in tag block transfers. A system comprises a tag buffer, a request buffer, and a memory controller. The request buffer stores a memory request having an associated tag. The memory controller compares the associated tag to a plurality of tags stored in the tag buffer and issues the memory request stored in the request buffer to either a memory cache or a main memory based on the comparison. | 06-26-2014 |
20150278091 | METHOD AND APPARATUS FOR IMPLEMENTING A HETEROGENEOUS MEMORY SUBSYSTEM - An apparatus and method for implementing a heterogeneous memory subsystem is described. For example, one embodiment of a processor comprises: memory mapping logic to subdivide a system memory space into a plurality of memory chunks and to map the memory chunks across a first memory and a second memory, the first memory having a first set of memory access characteristics and the second memory having a second set of memory access characteristics different from the first set of memory access characteristics; and dynamic remapping logic to swap memory chunks between the first and second memories based, at least in part, on a detected frequency with which the memory chunks are accessed. | 10-01-2015 |
James Sim, Evergreen Park, IL US
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20090276071 | MUTEX-MEDIATED CONTROL OF SPATIAL ACCESS BY APPLIANCES MOVEABLE OVER A COMMON PHYSICAL SPACE - A configurable mutual exclusion function oversees movement of appliances mobile over a common physical space in an automated laboratory workstation. A configurable mutex is allotted for each moveable appliance and is configurable to protect a task site when obtained for the respective appliance. | 11-05-2009 |
James W. Sim, Evergreen Park, IL US
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20130259635 | Lab Members and Liquid Handling Systems and Methods Including Same - A laboratory liquid handling system includes a pipetting module, a lab member, and a drive system. The pipetting module includes a pipettor including a pipettor shaft and a pipetting tip extending from an end of the pipettor shaft. The lab member includes a body and at least one adapter structure including an interlock feature configured to laterally receive and interlock with the pipettor shaft to releasably secure the lab member to the pipettor shaft. The drive system is operable to: selectively move the pipettor shaft laterally relative to the interlock structure to engage the pipettor shaft with the interlock structure to secure the lab member to the pipetting module; move the pipetting module to transport the lab member secured thereto; and selectively move the pipettor shaft laterally relative to the interlock structure to disengage the pipettor shaft from the interlock structure to thereby release the lab member. | 10-03-2013 |
20150251173 | LAB MEMBERS AND LIQUID HANDLING SYSTEMS AND METHODS INCLUDING SAME - A laboratory liquid handling system includes a pipetting module, a lab member, and a drive system. The pipetting module includes a pipettor including a pipettor shaft and a pipetting tip extending from an end of the pipettor shaft. The lab member includes a body and at least one adapter structure including an interlock feature configured to laterally receive and interlock with the pipettor shaft to releasably secure the lab member to the pipettor shaft. The drive system is operable to: selectively move the pipettor shaft laterally relative to the interlock structure to engage the pipettor shaft with the interlock structure to secure the lab member to the pipetting module; move the pipetting module to transport the lab member secured thereto; and selectively move the pipettor shaft laterally relative to the interlock structure to disengage the pipettor shaft from the interlock structure to thereby release the lab member. | 09-10-2015 |
Jang H. Sim, Fishkill, NY US
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20090146223 | PROCESS AND METHOD TO LOWER CONTACT RESISTANCE - A method removes the spacers from the sides of a transistor gate stack, and after the spacers are removed, the method implants an additional impurity into surface regions of the substrate not protected by the gate conductor (or alternatively just amorphizes these surface regions, without adding more impurity). The method then performs a laser anneal on the additional impurity (to activate the additional impurity) or amorphized regions (to recrystallize the amorphized regions). After this, permanent spacers are formed on the sidewalls of the gate conductor. Then, the surface regions of the substrate not protected by the gate conductor and the permanent spacers are silicided, to create silicide source/drain regions. This forms the silicide regions in the additional impurity or in the recrystallized amorphized regions to reduce the source/drain resistance by improving the active dopant concentration at the silicon-silicide interface. | 06-11-2009 |
Jang H. Sim, Hopewell Junction, NY US
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20090148988 | METHOD OF REDUCING EMBEDDED SIGE LOSS IN SEMICONDUCTOR DEVICE MANUFACTURING - Embodiments of the invention provide a method of forming embedded silicon germanium (eSiGe) in source and drain regions of a p-type field-effect-transistor (pFET) through a disposable spacer process; depositing a gap-filling layer directly on the eSiGe in the source and drain regions in a first process; depositing a layer of offset spacer material on top of the gap-filling layer in a second process different from the first process; etching the offset spacer material and the gap-filling layer, thus forming a set of offset spacers and exposing the eSiGe in the source and drain regions of the pFET; and finishing formation of the pFET. | 06-11-2009 |
Jong Hoan Sim, Austin, TX US
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20090294867 | DUAL METAL GATES USING ONE METAL TO ALTER WORK FUNCTION OF ANOTHER METAL - Methods of forming dual metal gates and the gates so formed are disclosed. A method may include forming a first metal (e.g., NMOS metal) layer on a gate dielectric layer and a second metal (e.g., PMOS metal) layer on the first metal layer, whereby the second metal layer alters a work function of the first metal layer (to form PMOS metal). The method may remove a portion of the second metal layer to expose the first metal layer in a first region; form a silicon layer on the exposed first metal layer in the first region and on the second metal layer in a second region; and form the dual metal gates in the first and second regions. Since the gate dielectric layer is continuously covered with the first metal, it is not exposed to the damage from the metal etch process. | 12-03-2009 |
20120256270 | DUAL METAL GATES USING ONE METAL TO ALTER WORK FUNCTION OF ANOTHER METAL - Methods of forming dual metal gates and the gates so formed are disclosed. A method may include forming a first metal (e.g., NMOS metal) layer on a gate dielectric layer and a second metal (e.g., PMOS metal) layer on the first metal layer, whereby the second metal layer alters a work function of the first metal layer (to form PMOS metal). The method may remove a portion of the second metal layer to expose the first metal layer in a first region; form a silicon layer on the exposed first metal layer in the first region and on the second metal layer in a second region; and form the dual metal gates in the first and second regions. Since the gate dielectric layer is continuously covered with the first metal, it is not exposed to the damage from the metal etch process. | 10-11-2012 |
Khan Qa Sim US
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20110162405 | Ice making unit and refrigerator having the same - An ice making unit and a refrigerator having the same are discussed. The refrigerator includes an ice making unit arranged in the ice making compartment, to produce ice, and a refrigeration cycle comprising a refrigerant pipe to supply cooling energy to the ice making compartment. Air present in the ice making compartment is cooled while undergoing direct heat exchange with at least one of the ice making unit and the refrigerant pipe. | 07-07-2011 |
Kim Lee Sim, Gaitherburg, MD US
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20090075369 | Angiostatin Fragments and Method of Use - Fragments of an endothelial cell proliferation inhibitor and method of use therefor are provided. The endothelial proliferation inhibitor is a protein derived from plasminogen, or more specifically is an angiostatin fragment. The angiostatin fragments generally correspond to kringle structures occurring within the endothelial cell proliferation inhibitor. The endothelial cell inhibiting activity of these fragments provides a means for inhibiting angiogenesis of tumors and for treating angiogenic-mediated disease. | 03-19-2009 |
Kwan Heum Sim US
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20150033573 | DEHYDRATOR - The present invention relates to a dehydrator, and more particularly, to a technology for achieving improved dehydration efficiency as compared to conventional technologies while maintaining a volume, dehydration time, and rotational speed that are nearly the same as those of conventional technologies. To this end, the dehydrator of the present invention comprises: a main body having an installation space therein; a pipe for supplying items to be dehydrated, which is located within the installation space of the main body, one side of which has an inlet hole for items to be dehydrated that is connected to the outside, inside which a supply space connected to the inlet hole for items to be dehydrated is disposed, and the other side of which has an outlet hole connected to the supply space; a dehydration tub, which is rotatably arranged, which surrounds the pipe for supplying items to be dehydrated in the installation space, inside which a dehydration space connected to the outlet hole is arranged, the circumferential surface of which has a dehydration hole for interconnecting the dehydration space and the installation space, and one side of which has a discharge port for connecting the dehydration space to the outside; a first driving unit connected to the dehydration tub so as to rotate the dehydration tub; and a discharge guide unit located within the dehydration space so as to move the item to be dehydrated placed in the dehydration space toward the discharge port. | 02-05-2015 |
Richard Sim US
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20120166285 | Defining and Verifying the Accuracy of Explicit Target Clusters in a Social Networking System - A cluster of users that share a common trait may be useful to a social networking system for various purposes, such as targeting advertising. Users of a social networking system are added to a cluster based on information about each user, which may include declared profile information, user history, and/or social information. The system initially adds users to a cluster based on a selected attribute and then verifies the accuracy of the cluster by sending a poll to a subset of the users in the cluster. The poll questions test whether the users are accurately in the cluster. The system may infer a specific life event, such as a recent engagement, from other information indicative of the life event, such as messages from a user's connections related to the engagement. The system then uses the poll to verify whether the inference is accurate. | 06-28-2012 |
Robert Sim, Bellevue, WA US
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20130091566 | INTERNET PROTOCOL ADDRESS SPACE MANAGEMENT TO MITIGATE AND DETECT CLOAKING AND OTHER ABUSE - In one embodiment, an intelligent detection system | 04-11-2013 |
20140039892 | USING THE ABILITY TO SPEAK AS A HUMAN INTERACTIVE PROOF - In one embodiment, a human interactive proof portal | 02-06-2014 |
Robert A. Sim, Bellevue, WA US
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20140156259 | Generating Stimuli for Use in Soliciting Grounded Linguistic Information - A processing system is described which generates stimulus information (SI) having one or more stimulus components (SCs) selected from an inventory of such components. The processing system then presents the SI to a group of human recipients, inviting those recipients to provide linguistic descriptions of the SI. The linguistic information that is received thereby has an implicit link to the SCs. Further, each linguistic component is associated with at least one feature of a target environment, such as a target computer system. Hence, the linguistic information also maps to the features of the target environment. These relationships allow applications to use the linguistic information to interact with the target environment in different ways. In one case, the processing system uses a challenge-response authentication task presentation to convey the stimulus information to the recipients. | 06-05-2014 |
Robert Alexander Sim, Bellevue, WA US
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20150339477 | RISK ASSESSMENT MODELING - One or more techniques and/or systems are provided for risk assessment. Historical authentication data and/or compromised user account data may be evaluated to identify a set of authentication context properties associated with user authentication sessions and/or a set of malicious account context properties associated with compromised user accounts (e.g., properties indicative of whether a user recently visited a malicious site, created a fake social network profile, logged in from unknown locations, etc.). The set of authentication context properties and/or the set of malicious account context properties may be annotated to create an annotated context property training set that may be used to train a risk assessment machine learning model to generate a risk assessment model. The risk assessment model may be used to evaluate user context properties of a user account event to generate a risk analysis metric indicative of a likelihood the user account event is malicious or safe. | 11-26-2015 |
Sylie Sim, La Vista, NE US
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20150064230 | SUSTAINED RELEASE DELIVERY OF ONE OR MORE AGENTS - The lacrimal implant delivery systems and methods described herein provide for controlled release of a therapeutic agent for the treatment of disease, including the treatment of glaucoma, ocular hypertension, or elevated intraocular pressure with latanoprost or other anti-glaucoma agents. Treatment of disease, including glaucoma, ocular hypertension, or elevated intraocular pressure with latanoprost or other anti-glaucoma agent in conjunction with penetration enhancer, such as benzalkonium chloride, and/or artificial tears is also provided. Also provided are implants containing a drug core emplacable in a punctum adjacent to an eye of a patient for controlled release of a therapeutic agent such as latanoprost for the treatment of glaucoma, the drug core containing a polymer such as cross-linked silicone, a therapeutic agent, and an excipient, wherein the excipient can increase the rate of release of the agent from the drug core, or can increase the drug loading in the core without loss of desirable homogeneity of the agent within the core, or can improve retention of the agent in the eye or in tear fluid, or can increase corneal penetration of the agent into the eye. | 03-05-2015 |
20150133546 | SUSTAINED RELEASE DELIVERY OF ONE OR MORE AGENTS - The lacrimal implant delivery systems and methods described herein provide for controlled release of a therapeutic agent for the treatment of disease, including the treatment of glaucoma, ocular hypertension, or elevated intraocular pressure with latanoprost or other anti-glaucoma agents. Treatment of disease, including glaucoma, ocular hypertension, or elevated intraocular pressure with latanoprost or other anti-glaucoma agent in conjunction with penetration enhancer, such as benzalkonium chloride, and/or artificial tears is also provided. Also provided are implants containing a drug core emplacable in a punctum adjacent to an eye of a patient for controlled release of a therapeutic agent such as latanoprost for the treatment of glaucoma, the drug core containing a polymer such as cross-linked silicone, a therapeutic agent, and an excipient, wherein the excipient can increase the rate of release of the agent from the drug core, or can increase the drug loading in the core without loss of desirable homogeneity of the agent within the core, or can improve retention of the agent in the eye or in tear fluid, or can increase corneal penetration of the agent into the eye. | 05-14-2015 |
Sylvie Sim, Omaha, NE US
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20100274224 | LACRIMAL IMPLANT BODY INCLUDING COMFORTING AGENT - Lacrimal implants for treating ocular diseases are disclosed. More particularly, lacrimal punctal plugs, methods of making such plugs, and methods of treating ocular diseases using such plugs are disclosed. | 10-28-2010 |
Sylvie Sim, La Vista, NE US
Patent application number | Description | Published |
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20100209477 | SUSTAINED RELEASE DELIVERY OF ONE OR MORE AGENTS - The lacrimal implant delivery systems and methods described herein provide for controlled release of a therapeutic agent for the treatment of disease, including the treatment of glaucoma, ocular hypertension, or elevated intraocular pressure with latanoprost or other anti-glaucoma agents. Treatment of disease, including glaucoma, ocular hypertension, or elevated intraocular pressure with latanoprost or other anti-glaucoma agent in conjunction with penetration enhancer, such as benzalkonium chloride, and/or artificial tears is also provided. Also provided are implants containing a drug core emplacable in a punctum adjacent to an eye of a patient for controlled release of a therapeutic agent such as latanoprost for the treatment of glaucoma, the drug core containing a polymer such as cross-linked silicone, a therapeutic agent, and an excipient, wherein the excipient can increase the rate of release of the agent from the drug core, or can increase the drug loading in the core without loss of desirable homogeneity of the agent within the core, or can improve retention of the agent in the eye or in tear fluid, or can increase corneal penetration of the agent into the eye. | 08-19-2010 |
Sylvie Sim, Ann Arbor, MI US
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20080226686 | GENERATION OF NITRIC OXIDE IN SITU AT SUBSTRATE/BLOOD INTERFACES AND REPRODUCIBLE NITRIC OXIDE SENSOR FOR DETECTING NITROSOTHIOLS - A material includes a surface and a reactive agent that is located at the surface of the material, covalently attached to a backbone of the material, and/or located within the material. The reactive agent has nitrite reductase activity, nitrate reductase activity, and/or nitrosothiol reductase activity. The reactive agent also converts at least one of nitrites, nitrates and nitrosothiols to nitric oxide when in contact with blood. A reproducible nitrosothiol sensor is also disclosed. | 09-18-2008 |
Teck Ping Sim, Waltham, MA US
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20140240373 | METHODS FOR DRIVING ELECTRO-OPTIC DISPLAYS - An electro-optic display having a plurality of pixels is driven from a first image to a second image using a first drive scheme, and then from the second image to a third image using a second drive scheme different from the first drive scheme and having at least one impulse differential gray level having an impulse potential different from the corresponding gray level in the first drive scheme. Each pixel which is in an impulse differential gray level in the second image is driven from the second image to the third image using a modified version of the second drive scheme which reduces its impulse differential The subsequent transition from the third image to a fourth image is also conducted using the modified second drive scheme but after a limited number of transitions using the modified second drive scheme, all subsequent transitions are conducted using the unmodified second drive scheme. | 08-28-2014 |
20140333685 | METHODS FOR DRIVING ELECTRO-OPTIC DISPLAYS - An electro-optic display has a plurality of pixels, each of which is capable of displaying two extreme optical states and at least one intermediate gray level. Each pixel is driven from an initial intermediate gray level to one extreme optical state and thence to a first desired intermediate gray level, so producing a first image on the display. The pixel then remains at this first desired intermediate gray level for a finite length of time. The pixel is then driven from this first desired intermediate gray level to the opposed extreme optical state and thence to a second desired intermediate gray level, so producing a second image on the display. | 11-13-2014 |
Vibora Sim, Pflugerville, TX US
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20110026228 | Retractable Circuit Board Guide And Bracket - A circuit board guide and bracket apparatus includes a first member collapsibly attached to a second member. The first member is attachable to a planar member in a chassis. The second member guides a circuit board being mounted into a connector on the planar member and supports the board subsequent to being mounted. | 02-03-2011 |
20110310546 | EMI Shielding Scheme Using Sandwiched Sheet Metal - A peripheral card EMI shielding scheme which comprises a sandwich of three layers. The first layer comprises a chassis rear wall (e.g., constructed of sheet metal). The next layer, which in certain embodiments is the middle of the sandwich, comprises a relatively thin plate (e.g., 0.15 mm+/−0.1 mm) with spring arms. The third layer comprises a sheet metal plate (in certain embodiments, the third layer has a similar thickness to the rear wall). The thick sheet metal plate completely covers the thin plate, except for areas where the spring arms protrude. The three plates are staked together by a method similar to an extrude-and-roll process (e.g., where one piece is fastened to another without the need for additional hardware or welding). | 12-22-2011 |
20140084764 | Locking Mechanism for Adaptor Assembly of a Server Rack Chassis - A locking mechanism includes a latch, a handle, a first link, and a second link. The latch to engage with a recess of a server rack chassis, and to lock an adaptor assembly within the server rack chassis. The handle is connected to the latch, and engages and disengages the latch with the recess. The first link includes a first stub. The first link puts the first stub in an up position in response to the handle being in a down position, and puts the first stub in a down position in response to the handle being in an up position. The second link includes a second stub. The second link puts the second stub in a down position in response to the handle being in the down position, and puts the second stub in an up position in response to the handle being in the up position. | 03-27-2014 |
20150084489 | Locking Mechanism for Adaptor Assembly of a Server Rack Chassis - A locking mechanism includes a latch, a handle, a first link, and a second link. The latch to engage with a recess of a server rack chassis, and to lock an adaptor assembly within the server rack chassis. The handle is connected to the latch, and engages and disengages the latch with the recess. The first link includes a first stub. The first link puts the first stub in an up position in response to the handle being in a down position, and puts the first stab in a down position in response to the handle being in an up position. The second link includes a second stub, The second link puts the second stub in a down position in response to the handle being in the down position, and puts the second stub in an up position in response to the handle being in the up position. | 03-26-2015 |
Vibora Sim, Spring, TX US
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20140108692 | System and Method for Integrating Multiple Servers into Single Full Height Bay of a Server Rack Chassis - An information handling system includes a server rack chassis, an adaptor assembly, and second and third servers. The server rack chassis includes a bay adapted to receive a first server that has a height that is substantially equal to a height of the bay. The adaptor assembly is inserted within the bay and includes first, second, third, and fourth slots to receive servers. The adaptor assembly is substantially the same size and dimension as the first server. The second server is inserted within the first slot of the adaptor assembly, and includes a first communication fabric. The height of the second server is substantially equal to a quarter of the height of the bay. The third server is inserted within the second slot of the adaptor assembly, and includes a second communication fabric. The height of the third server is substantially equal to a quarter of the height of the bay. | 04-17-2014 |
Wei Lin Sandra Sim US
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20150344471 | COMPOUNDS AND COMPOSITIONS FOR THE TREATMENT OF PARASITIC DISEASES - The present invention provides compounds of formula I: | 12-03-2015 |
William James Sim US
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20090161885 | Component for noise reducing earphone - An active noise reduction (ANR) component for provision in an earphone housing is disclosed. The device includes a driver and a sensing microphone, the driver and sensing microphone being housed in a component housing. The earphone housing has an outlet passageway from the ANR component to an auditory canal. The ANR component is adapted for use with a controller to provide active noise reduction to the auditory canal over a predetermined range of physical dimensions or acoustic parameters of the housing outlet passageway. The ANR component can thus be used with different housings which simplifies the design process for producing ANR earphone products. | 06-25-2009 |