Patent application number | Description | Published |
20100087408 | NON-HORMONAL STEROID MODULATORS OF NF-kB FOR TREATMENT OF DISEASE - The present invention relates to compounds and methods which may be useful as treatments of neuromuscular diseases such as muscular dystrophy, and as inhibitors of NF-κB for the treatment or prevention of muscular wasting disease, including muscular dystrophy. | 04-08-2010 |
20120094970 | NON-HORMONAL STEROID MODULATORS OF NF-kB FOR TREATMENT OF DISEASE - The present invention relates to compounds and methods which may be useful as treatments of neuromuscular diseases such as muscular dystrophy, and as inhibitors of NF-κB for the treatment or prevention of muscular wasting disease, including muscular dystrophy. | 04-19-2012 |
20130196962 | NON-HORMONAL STEROID MODULATORS OF NF-KB FOR TREATMENT OF DISEASE - The present invention relates to compounds and methods which may be useful as treatments of neuromuscular diseases such as muscular dystrophy, and as inhibitors of NF-κB for the treatment or prevention of muscular wasting disease, including muscular dystrophy. | 08-01-2013 |
20140142078 | NON-HORMONAL STEROID MODULATORS OF NF-kB FOR TREATMENT OF DISEASE - The present invention relates to compounds and methods which may be useful as treatments of neuromuscular diseases such as muscular dystrophy, and as inhibitors of NF-κB for the treatment or prevention of muscular wasting disease, including muscular dystrophy. | 05-22-2014 |
20140350069 | METHODS AND AGENTS TO INCREASE THERAPEUTIC DYSTROPHIN EXPRESSION IN MUSCLE - Agents and methods for increasing dystrophin protein expression in muscle through blocking of specific microRNAs and microRNA binding sites on the dystrophin 3′ untranslated region (miR-146a, miRNA-146b, miR-223, miR-320a, miR374a, and miR-382). Methods for increasing the amount of dystrophin useful for effective therapeutic intervention for Becker muscular dystrophy, Duchenne muscular dystrophy, and other disorders where loss of dystrophin from muscle causes pathology. | 11-27-2014 |
Patent application number | Description | Published |
20090240612 | Life Insurance Cooperative - A business method and computing system for providing a death benefit to a participant having an uninsurable trait. The method collects registration information from the participant, and associates the participant with at least one other participant having the uninsurable trait to form a group of participants. The method receives a funding payment from each participant in the group to create a funding pool for a time period. The method disburses the funding pool to deceased participants in the group who died during the time period, each deceased participant receiving a portion of the funding pool. An amount of the portion of the funding pool for each deceased participant is the death benefit for the deceased participant. | 09-24-2009 |
20100268554 | Life Insurance Cooperative - A business method and computing system for providing a death benefit to a participant having an uninsurable trait. The method collects registration information from the participant, and associates the participant with at least one other participant having the uninsurable trait to form a group of participants. The method receives a funding payment from each participant in the group to create a funding pool for a time period. The method disburses the funding pool to deceased participants in the group who died during the time period, each deceased participant receiving a portion of the funding pool. An amount of the portion of the funding pool for each deceased participant is the death benefit for the deceased participant. | 10-21-2010 |
20130041695 | Life Insurance Cooperative - A method in a server computer connected over a network to a group of participants, where each participant operates a client computer. The method receives a payment for each participant in the group, associates the payments received for the group with a time period, calculates a designated portion of each payment, and creates a fund for the time period by combining the designated portions of the payments. The method receives a notification for each participant in a subgroup of the group of participants, where the notification indicates that during the time period an event occurred. The method calculates a portion of the fund to disburse to each participant in the subgroup, and disburses the fund to the participants in the subgroup, where the portion of the fund to disburse to each participant in the subgroup is a share of the fund. | 02-14-2013 |
Patent application number | Description | Published |
20100020832 | WAVELENGTH SELECTABLE LASER SYSTEMS AND RELATED METHODS - Laser systems and related methods are provided. In this regard, a representative laser system includes: a laser diode array that generates light; a first crystal having a cavity; an optical element operative to focus the generated light onto the first crystal such that the light generates a high-power circulating beam within the cavity; a second crystal positioned with respect to the first crystal such that the frequency of the high-power circulating beam is doubled; and a first coating applied to the first crystal and second coating applied to the second crystal, the first coating and the second coating being operative to cause at least a portion of the beam to be emitted within a particular wavelength range of the generated light. | 01-28-2010 |
20100020836 | USE OF CURRENT CHANNELING IN MULTIPLE NODE LASER SYSTEMS AND METHODS THEREOF - Current channels, blocking areas, or strips in a semiconductor laser are used to channel injected current into the antinodal region of the optical standing wave present in the optical cavity, while restricting the current flow to the nodal regions. Previous devices injected current into both the nodal and antinodal regions of the wave, which is fed by the population inversion created in the active region by the injected electrons and holes, but inversion created in the nodal regions is lost to fluorescence or supports the creation of undesirable competing longitudinal modes, causing inefficiency. Directing current to the antinodal regions where the electric field is at its maximum causes a selected longitudinal mode to preferentially oscillate regardless of where the longitudinal mode lies with respect to the gain curve. In one embodiment, exacting fabrication of the Fabry-Perot cavity correlates the current channels to antinodal regions, vis-a vis current blocking areas, strips or segmented layers. | 01-28-2010 |
20100102204 | ACTIVE OPTICAL LIMITING SEMICONDUCTOR DEVICE AND METHODS - An optical switching system comprising an embodiment with a high pass filter operable to eliminate a portion of frequencies present in an image and an optical device operative to receive the spectrally modified image from the high pass filter, alternatively amplify the spectrally modified image, and propagate at least those frequency components in the spectrally modified image exhibiting a frequency less than an absorption frequency of the optical switching device when the optical switching device is active. Alternatively, the optical switching system may transmit an image only when the system is active. The optical switching system may, for example, comprise superluminescent light emitting diodes which may be, for example, formed in the shape of an inverted truncated prism. For human viewing purposes, the operative transmission ranges may closely coincide with the maximum sensitivity of the photopic response of the corresponding red, blue and green cones in human eyes. | 04-29-2010 |
20100111124 | PUMPED SEMICONDUCTOR LASER SYSTEMS AND METHODS - A method for emitting laser radiation includes: emitting first laser radiation using a first laser, wherein said first laser is a laser diode; receiving the first laser radiation by a second laser comprising CdSe | 05-06-2010 |
20100321756 | Large Aperture Polymer Electro-Optic Shutter Device and Method of Manufacturing Same - A large-aperture direct-view high-speed electro-optic shutter includes an electro-optic polymer material constructed to form a Pockels cell and an integrated photoconducting semiconductor switch. A chromophore-doped polymer material or chromophore copolymer, wherein the chromophore is oriented within the polymer material, exhibits a linear electro-optic effect when an electric field is applied to the device. In one embodiment, the polymer host material comprises one or more of a polycarbonate, amorphous polycarbonate, or polymethylmethacrylate polymer hosts. The optically active chromophore comprising one or more coumarin and coumarin derivatives, stilbene or tolane derivatives is incorporated within the polymer host, forming a guest-host polymer. In another embodiment, the chromophore is chemically bonded to the monomer that forms the polymer, resulting in an optically active copolymer. The electro-optic shutter device is then activated by incident light through the photoconducting semiconductor switch, rendering the Pockels cell to have an optical density of at least 3.0. | 12-23-2010 |
20120170099 | Large Aperture Polymer Electro-Optic Shutter Device and Method of Manufacturing Same - A large-aperture direct-view high-speed electro-optic shutter includes an electro-optic polymer material constructed to form a Pockels cell and an integrated photoconducting semiconductor switch. A chromophore-doped polymer material or chromophore copolymer, wherein the chromophore is oriented within the polymer material, exhibits a linear electro-optic effect when an electric field is applied to the device. In one embodiment, the polymer host material comprises one or more of a polycarbonate, amorphous polycarbonate, or polymethylmethacrylate polymer hosts. The optically active chromophore comprising one or more coumarin and coumarin derivatives, stilbene or tolane derivatives is incorporated within the polymer host, forming a guest-host polymer. In another embodiment, the chromophore is chemically bonded to the monomer that forms the polymer, resulting in an optically active copolymer. The electro-optic shutter device is then activated by incident light through the photoconducting semiconductor switch, rendering the Pockels cell to have an optical density of at least 3.0. | 07-05-2012 |