Patent application number | Description | Published |
20110277558 | ULTRASOUND MEASUREMENT OF THE FLOW SPEED OF A FLUID IN A CONDUIT - An ultrasound measurement apparatus ( | 11-17-2011 |
20120060623 | METHOD OF OPERATING AN ULTRASONIC GAS FLOW METER AND AN ULTRASONIC GAS FLOW METER - The invention relates to a method of operating an ultrasonic gas flow meter, the ultrasonic gas flow meter including at least one signal evaluation unit, at least one memory, a piping through which gas can flow, at least one pair of ultrasonic transducers disposed on opposite sides of the piping and separated by a path inclined to a flow direction of the piping, wherein each ultrasonic transducer is connected to an electronic circuit to selectively act as an ultrasonic transmitter and an ultrasonic receiver, wherein the ultrasonic gas flow meter is adapted to detect a flow velocity of the gas flowing through the piping on the basis of differences between propagation times of ultrasonic signals transmitted and received between each pair of transducers and propagating in opposite directions along the path, wherein the method includes a test procedure for verifying the operation of electronics associated with the ultrasonic gas flow meter wherein, when the test procedure is activated, test signals are triggered which replace the propagation times measured with predefined propagation times associated with an assumed gas flow velocity and the output of the evaluation unit is detected to see how the calculated gas flow velocity compares to the assumed gas flow velocity. The invention also relates to a corresponding ultrasonic gas flow meter. | 03-15-2012 |
20120060944 | METHOD AND APPARATUS FOR MEASURING A GAS FLOW VELOCITY - The invention relates to a method of measuring a gas flow velocity using an ultrasonic gas flow meter, wherein said ultrasonic gas flow meter includes a horizontal piping through which gas can flow in a flow direction and which has a central axis, at least one pair of measurement paths of equal length spaced apart, extending parallel to one another in separate horizontal planes and inclined to said flow direction, wherein each horizontal plane of a pair of measurement paths is vertically offset by an equal predefined distance from said central axis, wherein an ultrasonic transducer is arranged at each end of said measurement path and each ultrasonic transducer is adapted to selectively act as an ultrasonic transmitter and an ultrasonic receiver, the method comprising the steps of measuring a flow velocity of said gas in a measurement path arranged in an upper region of said piping, measuring a flow velocity of said gas in a measurement path arranged in a lower region of said piping and using the results of these two measurements to predict if a liquid is present in said piping during said measurement. | 03-15-2012 |
20120090404 | ULTRASONIC MEASUREMENT OF FLOW VELOCITY - An ultrasonic measurement device ( | 04-19-2012 |
20140303909 | Ultrasonic Meter Flow Measurement Monitoring System - The present invention provides an automated meter station monitoring system for a fluid comprising a processor having algorithms for verifying performance of a fluid flow measurement system. A pressure sensor is operatively connected to the processor to measure the pressure of the fluid. A temperature sensor is operatively connected to the processor to measure the temperature of the fluid. A gas chromatograph is operatively connected to the processor to monitor changes in gas composition and chromatograph response factors of the fluid. An ultrasonic meter is operatively connected to the processor to monitor the velocity of the fluid, speed of sound of the fluid, and meter diagnostics. A flow computer is operatively connected to the processor to record pressure of the fluid, record temperature of the fluid, record gas composition of the fluid, calculate compressibility ratio of the fluid, calculate standard flow rate of the fluid, and calculate energy rate of the fluid. | 10-09-2014 |
Patent application number | Description | Published |
20090237078 | METHODS OF EVALUATING PEPTIDE MIXTURES - The presently disclosed subject matter provides methods for evaluating and characterizing peptides, peptide mixtures, and polypeptide mixtures. More particularly, the presently disclosed subject matter provides methods for evaluating or characterizing complex peptide or polypeptide mixtures comprising glutamic acid, alanine, tyrosine, and lysine, e.g., Copolymer-1 or glatiramer acetate, including, but not limited to, methods of identifying, isolating, quantifying, and purifying amino acids, peptides, polypeptides, and combinations thereof having a diethylamide group instead of a carboxyl group present on the C-terminus. The presently disclosed methods can be used to determine the mole percent of polypeptides having a diethylamide group at a C-terminus thereof and can be used to evaluate one or more properties of a sample of one polypeptide mixture as compared to one or more properties of a different sample of a polypeptide mixture. | 09-24-2009 |
20100188084 | COMPARATIVE ANALYSIS OF PROTEIN CONFORMATIONS BY USING 2D NOESY NMR SPECTRA - The present disclosure provides a method for determining the relative conformations of a protein provided in different protein preparations, comprising steps of: (i) obtaining a first 2D NOESY NMR spectrum of a first protein preparation; (ii) obtaining a second 2D NOESY NMR spectrum of a second protein preparation; and (iii); determining whether a protein has a different conformation in the first and second protein preparations by comparing one or more cross-peaks in the first 2D NOESY NMR spectrum with one or more corresponding cross-peaks in the second 2D NOESY NMR spectrum. | 07-29-2010 |
20100279269 | CHARACTERIZATION OF N-GLYCAN MIXTURES BY NUCLEAR MAGNETIC RESONANCE - The present disclosure provides nuclear magnetic resonance (NMR) methods for characterizing mixtures of N-linked glycans. Without limitation, methods of the present disclosure may be useful in characterizing monosaccharide composition, branching, fucosylation, sulfation, phosphorylation, sialylation linkages, presence of impurities and/or efficiency of a labeling procedure (e.g., labeling with a fluorophore such as 2-AB). In certain embodiments, the methods can be used quantitatively. In certain embodiments, the methods can be combined with enzymatic digestion to further characterize glycan mixtures. | 11-04-2010 |
20130069645 | CHARACTERIZATION OF N-GLYCAN MIXTURES BY NUCLEAR MAGNETIC RESONANCE - The present disclosure provides nuclear magnetic resonance (NMR) methods for characterizing mixtures of N-linked glycans. Without limitation, methods of the present disclosure may be useful in characterizing monosaccharide composition, branching, fucosylation, sulfation, phosphorylation, sialylation linkages, presence of impurities and/or efficiency of a labeling procedure (e.g., labeling with a fluorophore such as 2-AB). In certain embodiments, the methods can be used quantitatively. In certain embodiments, the methods can be combined with enzymatic digestion to further characterize glycan mixtures. | 03-21-2013 |
20140127735 | CHARACTERIZATION OF N-GLYCAN MIXTURES BY NUCLEAR MAGNETIC RESONANCE - The present disclosure provides nuclear magnetic resonance (NMR) methods for characterizing mixtures of N-linked glycans. Without limitation, methods of the present disclosure may be useful in characterizing monosaccharide composition, branching, fucosylation, sulfation, phosphorylation, sialylation linkages, presence of impurities and/or efficiency of a labeling procedure (e.g., labeling with a fluorophore such as 2-AB). In certain embodiments, the methods can be used quantitatively. In certain embodiments, the methods can be combined with enzymatic digestion to further characterize glycan mixtures. | 05-08-2014 |
Patent application number | Description | Published |
20140011727 | Methods of Evaluating Peptide Mixtures - The presently disclosed subject matter provides methods for evaluating and characterizing peptides, peptide mixtures, and polypeptide mixtures. More particularly, the presently disclosed subject matter provides methods for evaluating or characterizing complex peptide or polypeptide mixtures comprising glutamic acid, alanine, tyrosine, and lysine, e.g., Copolymer-1 or glatiramer acetate, including, but not limited to, methods of identifying. isolating, quantifying, and purifying amino acids, peptides, polypeptides, and combinations thereof having a diethylamide group instead of a carboxyl group present on the C-terminus. The presently disclosed methods can be used to determine the mole percent of polypeptides having a diethylamide group at a C-terminus thereof and can be used to evaluate one or more properties of a sample of one polypeptide mixture as compared to one or more properties of a different sample of a polypeptide mixture. | 01-09-2014 |
20140045204 | EVALUATION OF COPOLYMER DIETHYLAMIDE - Methods of analyzing glatiramer acetate (GA) or a polymeric precursor thereof are provided. The methods can include determining a level of one or more diethylamide-modified amino acids in a sample comprising GA or a polymeric precursor thereof, and selecting at least a portion of the sample based on the assessment of the one or more diethylamide-modified amino acids in the sample. | 02-13-2014 |
20140046024 | EVALUATION OF COPOLYMER DIETHYLAMIDE - Methods of analyzing glatiramer acetate (GA) or a polymeric precursor thereof are provided. The methods can include determining a level of one or more diethylamide-modified amino acids in a sample comprising GA or a polymeric precursor thereof, and selecting at least a portion of the sample based on the assessment of the one or more diethylamide-modified amino acids in the sample. | 02-13-2014 |
20140080218 | METHODS OF EVALUATING PEPTIDE MIXTURES - The presently disclosed subject matter provides methods for evaluating and characterizing peptides, peptide mixtures, and polypeptide mixtures. More particularly, the presently disclosed subject matter provides methods for evaluating or characterizing complex peptide or polypeptide mixtures comprising glutamic acid, alanine, tyrosine, and lysine, e.g., Copolymer-1 or glatiramer acetate, including, but not limited to, methods of identifying, isolating, quantifying, and purifying amino acids, peptides, polypeptides, and combinations thereof having a diethylamide group instead of a carboxyl group present on the C-terminus. The presently disclosed methods can be used to determine the mole percent of polypeptides having a diethylamide group at a C-terminus thereof and can be used to evaluate one or more properties of a sample of one polypeptide mixture as compared to one or more properties of a different sample of a polypeptide mixture. | 03-20-2014 |
20150252108 | GLYCOPROTEIN PREPARATIONS - Preparations of glycoproteins, e.g., therapeutic preparations of glycoproteins, having altered levels of affinity for Fcγ receptors relative to reference glycoprotein preparations, and methods of making and methods of using such preparations, are described. | 09-10-2015 |
Patent application number | Description | Published |
20110103385 | Apparatus and Method for Hardware Payload Header Suppression, Expansion, and Verification - The present invention provides methods for performing payload header suppression (PHS), expansion, and verification in hardware. A PHS verify circuit reads a data packet until it reaches the location where the first byte must be compared to PHS rule verify bytes. Next, all the relevant bytes in the payload header are compared to the PHS vile verify bytes obtained from a payload header suppression rule mask. Upon completion of the compare, a flag is generated to a PHS suppress circuit indicating that verification has passed or failed. For payload headers passing the verification process, the payload header suppress circuit examines the payload header suppression mask to identify one or more bits in the payload header for which an associated byte string is to be suppressed. Next, the associated byte string for each of the identified bits are suppressed to generate a suppressed packet payload header. Finally, a payload header suppression index is added to the suppressed packet payload header. The data packet, including the suppressed packet header and suppression index are then transmitted. Once received, a payload header suppress circuit on the receiver end examines the payload header suppression index to determine if the payload header has been suppressed. For each suppressed payload header, each bit in the payload header is compared to a payload header suppression mask to determine if the bit has been suppressed. Next, for each suppressed bit, a byte string is retrieved from a payload header suppression rule and inserted into the suppressed payload header. | 05-05-2011 |
20110200048 | Modem with Voice Processing Capability - A system is configured to facilitate bidirectional voice communication between a number of data and/or telephony devices. | 08-18-2011 |
20140064267 | Modem With Voice Processing Capability - A network gateway is configured to facilitate on line and off line bi-directional communication between a number of near end data and telephony devices with far end data termination devices via a hybrid fiber coaxial network and a cable modem termination system. The described network gateway combines a QAM receiver, a transmitter, a DOCSIS MAC, a CPU, a voice and audio processor, a voice synchronizer, an Ethernet MAC, and a USB controller to provide high performance and robust operation. | 03-06-2014 |
Patent application number | Description | Published |
20100202457 | Highly Integrated Media Access Control - A supervisory communications device, such as a headend device within a communications network, monitors and controls communications with a plurality of remote communications devices throughout a widely distributed network. The supervisory device allocates bandwidth on the upstream channels by sending MAP messages over its downstream channel. A highly integrated media access controller integrated circuit (MAC IC) operates within the headend to provide lower level processing on signals exchanged with the remote devices. The enhanced functionality of the MAC IC relieves the processing burden on the headend CPU and increases packet throughput. The enhanced functionality includes header suppression and expansion, DES encryption and decryption, fragment reassembly, concatenation, and DMA operations | 08-12-2010 |
20110274122 | Highly Integrated Media Access Control - A supervisory communications device, such as a headend device within a communications network, monitors and controls communications with a plurality of remote communications devices throughout a widely distributed network. The supervisory device allocates bandwidth on the upstream channels by sending MAP messages over its downstream channel. A highly integrated media access controller integrated circuit (MAC IC) operates within the headend to provide lower level processing on signals exchanged with the remote devices. The enhanced functionality of the MAC IC relieves the processing burden on the headend CPU and increases packet throughput. The enhanced functionality includes header suppression and expansion, DES encryption and decryption, fragment reassembly, concatenation, and DMA operations. | 11-10-2011 |
20130279523 | Highly Integrated Media Access Control - A supervisory communications device, such as a headend device within a communications network, monitors and controls communications with a plurality of remote communications devices throughout a widely distributed network. The supervisory device allocates bandwidth on the upstream channels by sending MAP messages over its downstream channel. A highly integrated media access controller integrated circuit (MAC IC) operates within the headend to provide lower level processing on signals exchanged with the remote devices. The enhanced functionality of the MAC IC relieves the processing burden on the headend CPU and increases packet throughput.. The enhanced functionality includes header suppression and expansion. DES encryption and decryption, fragment reassembly, concatenation, and DMA operations. | 10-24-2013 |