Weight
Alisha Weight, Mill Creek, WA US
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20130280204 | Polymer-Attached Inhibitors of Influenza Virus - Antiviral compositions containing one or more antiviral agents coupled to a polymer and methods of making and using the compositions, are described herein. The one or more antiviral agents are covalently coupled to the polymer, and thereby prevent or decrease development of drug resistance. In some embodiments, the polymer is a biodegradable polymer. In particular embodiments, the polymer is a water-soluble, biodegradable polymer, which has an overall neutral charge (e.g., no charged groups or overall neutral charge). In a more particular embodiment, the neutral polymer is polyglutamine or a polymer having properties similar to polyglutamine, polyaspartate, and other homopolypeptides that can be modified to have no charge or no net charge. The compositions described herein are effective at treating a variety of viral infections, such as influenza, respiratory syncythial virus, rhinovirus, human metaneumovirus, and other respiratory diseases, while inhibiting or preventing the development of resistance. | 10-24-2013 |
Alisha K. Weight, Mill Creek, WA US
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20150071920 | LIQUID PROTEIN FORMULATIONS CONTAINING WATER SOLUBLE ORGANIC DYES - Concentrated, low-viscosity, low-volume liquid pharmaceutical formulations of proteins have been developed. Such formulations can be rapidly and conveniently administered by subcutaneous or intramuscular injection, rather than by lengthy intravenous infusion. These formulations include low-molecular-weight and/or high-molecular-weight proteins, such as mAbs, and viscosity-lowering water soluble organic dyes. | 03-12-2015 |
20150071921 | LIQUID PROTEIN FORMULATIONS CONTAINING ORGANOPHOSPHATES - Concentrated, low-viscosity, low-volume liquid pharmaceutical formulations of proteins have been developed. Such formulations can be rapidly and conveniently administered by subcutaneous (SC) or intramuscular (IM) injection, rather than by lengthy intravenous infusion. These formulations include low-molecular-weight and/or high-molecular-weight proteins, such as mAbs, and organophosphates. The viscosity of the formulation is significantly reduced by the addition of one or more organophosphates. | 03-12-2015 |
20150071922 | LIQUID PROTEIN FORMULATIONS CONTAINING IONIC LIQUIDS - Concentrated, low-viscosity, low-volume liquid pharmaceutical formulations of proteins have been developed. Such formulations can be rapidly and conveniently administered by subcutaneous or intramuscular injection, rather than by lengthy intravenous infusion. These formulations include low-molecular-weight and/or high-molecular-weight proteins, such as mAbs, and viscosity-reducing ionic liquids. | 03-12-2015 |
20150071925 | LIQUID PROTEIN FORMULATIONS CONTAINING VISCOSITY-LOWERING AGENTS - Concentrated, low-viscosity, low-volume liquid pharmaceutical formulations of proteins have been developed. Such formulations can be rapidly and conveniently administered by subcutaneous or intramuscular injection, rather than by lengthy intravenous infusion. These formulations include low-molecular-weight and/or high-molecular-weight proteins, such as mAbs, and viscosity-lowering agents that are typically bulky polar organic compounds, such as many of the GRAS (US Food and Drug Administration List of compounds generally regarded as safe) and inactive injectable ingredients and FDA approved therapeutics. | 03-12-2015 |
Alistair N. Weight, Raynes Park GB
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20140345174 | PANELS | 11-27-2014 |
Brent L. Weight, St. George, UT US
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20130295663 | Pressurizable Cartridge for Polymerase Chain Reactions - Methods and apparatus for use in connection with the performance of the polymerase chain reaction are provided. An exemplary sample processing module is described that includes a sample assembly and a PCR assembly, the sample processing module being configured to hold the sample therein at a pressure higher than ambient pressure. A sample is added to the sample assembly at the time of use, which is then connected to the PCR assembly. Embodiments of the cartridge include a flow restriction device that enables or aids in creating a higher pressure within the reaction vial. The sample is introduced into a PCR reaction vial, which contains all of the constituents of a PCR reaction mixture that are necessary to process the sample and provide amplified DNA of interest, if that DNA was present in the sample. | 11-07-2013 |
Christopher J. Weight, Shaker Heights, OH US
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20100184015 | METHOD FOR DETECTION OF XMRV - The present invention relates to the identification of Xenotropic murine leukemia virus (XMRV) nucleic acid by polymerase chain reaction (PCR) analysis (e.g., real time PCR (RT/PCR); nested RT/PCR using Tth DNA polymerase and Hot start polymerase) and the uses thereof. In particular, the invention provides methods for the detection, and in particular early detection, of XMRV in RNA isolated from samples (e.g., urine samples; expressed prostate secretion (EPS)) of prostate cancer patients and normal individuals. | 07-22-2010 |
Hadley W. Weight, Mitcham Surrey GB
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20140345174 | PANELS | 11-27-2014 |
Kenneth Weight, Hampshire GB
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20080230488 | Pleated, Crossflow Fluid Treatment Elements, Methods for Making Them, and Methods for Treating Cellular Solutions - Fluid treatment elements and methods for treating fluids may be used to treat fluids, including gases, liquids, or mixtures of gases, and/or solids, in a crossflow mode of operation. For example, some fluid treatment elements and methods may be used to remove one or more substances from the fluid and may then function as concentrators or filters or separators. Other fluid treatment elements or methods may be used to transfer substances between two fluid streams and may then function as mass transfer devices. | 09-25-2008 |
Kenneth Roy Weight, Denmead GB
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20090236338 | BIOCONTAINER - The present invention relates to a flexible, closed container with a bottom wall, a top wall and four side walls of a substantial rectangular configuration and made of a flexible plastic sheet material, said container comprising at least a first port, said bottom, top and side walls being provided by four separate sheets which are joined together at their edges, wherein a first sheet forms said bottom wall, a second sheet forms said top wall and a third and a fourth sheet form a first and a second side wall at two opposite sides of the container, said four sheets each comprising in addition to the portions forming the bottom, top and first and second side walls integrally formed triangular or trapezoid shaped wall portions at opposite ends thereof, said triangular or trapezoid shaped wall portions form when joined together a third and a fourth side wall, respectively, wherein said bottom wall accommodates said first port in an off-centre position. | 09-24-2009 |
Kenneth Roy Weight, Hampshire GB
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20130157355 | ROCKABLE BIOCONTAINER - Biocontainers, as well as methods and platforms for rocking the biocontainers, are disclosed. | 06-20-2013 |
Russell H. Weight, Hillsboro, OR US
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20090150719 | AUTOMATICALLY FREEZING FUNCTIONALITY OF A COMPUTING ENTITY RESPONSIVE TO AN ERROR - Facilitating error handling of computing environments, including those environments having file systems. Responsive to an entity of the computing environment, such as a client of a file system, obtaining at least an indication of an error, a portion of functionality of the entity is automatically frozen. The obtaining is, for instance, responsive to an event of another entity of the computing environment, such as a server of the file system. Eventually, the frozen functionality is thawed allowing the functionality to proceed. | 06-11-2009 |
20090307670 | OPTIMIZATION OF SYSTEM PERFORMANCE THROUGH SCENARIO EVALUATION - A system, method and computer program product for optimizing a software system through scenario evaluation. In accordance with the disclosed technique, a request is received for evaluation of an operational scenario that operates over an environment that is a superset of existing system capabilities encompassing system features or parameters that are not available in the currently running system. A knowledge base is consulted to derive recommendations with respect to operating parameters that may be collected to evaluate the scenario, mechanisms for gathering data relating to the parameters, and data evaluator operations for deriving a data evaluation result based on the data gathering. The knowledge base is further consulted to determine a reconfiguration recommendation based on the result. Scenario evaluation is performed based on simulation of the reconfiguration recommendation using the data evaluation result to determine efficacy of the scenario. | 12-10-2009 |
20100037073 | Apparatus and Method for Selective Power Reduction of Memory Hardware - Apparatus and Method for Selective Power Reduction of Memory Hardware A method and apparatus are provided for managing delivery of power to one or more hardware memory devices in a computer system. The computer system is configured with a processor and at least two hardware memory devices. An energy exchange threshold for the computer system is set, and management of one or more of the hardware memory devices is employed when the computer system exceeds an energy exchange threshold. | 02-11-2010 |
20120216057 | Selective Power Reduction of Memory Hardware - Managing delivery of power to one or more hardware memory devices in a computer system. The computer system is configured with a processor and at least two hardware memory devices. A temperature monitor tool is employed to monitor the hardware memory devices. Management of an addressable subset of the hardware memory devices is employed in response to the monitored temperature reading. | 08-23-2012 |
Ryan M. Weight, Avondale, MO US
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20090170149 | PHOTO-ACOUSTIC DETECTION DEVICE AND METHOD - An example system for detecting an analyte in a sample of a bodily fluid comprises a test chamber having at least one sidewall and configured to contain at least a portion of a bodily fluid sample, an excitation electromagnetic energy source configured to direct an energy source into the test chamber through the at least one sidewall and to induce a thermoelastic expansion in the one or more analytes, and a sensor configured to detect said thermoelastic expansion in the bodily fluid sample in the test chamber, the sensor configured to measure changes in optical reflectance that result from the thermoelastic expansion. | 07-02-2009 |
Ryan M. Weight, St. Joseph, MO US
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20110217762 | PHOTO-ACOUSTIC DETECTION DEVICE AND METHOD - An example method for detecting an analyte in a sample of a bodily fluid comprises the steps of exposing the bodily fluid sample to electromagnetic energy to cause a thermoelastic expansion in the analyte, and detecting a photoacoustic signal in the sample that results from the thermoelastic expansion. | 09-08-2011 |