Patent application number | Description | Published |
20090215175 | MODULATION OF THE POLIOVIRUS RECEPTOR FUNCTION - The present invention relates to the identification, the isolation and the use of molecules interfering with the function (s) mediated by the poliovirus receptor (PVR) on cells. The molecules can be used for the treatment of cells having a metastatic potential, metastasis and cancer. Further methods are provided that are useful for identifying and isolating molecules, which have the capacity to modulate PVR mediated adhesion or invasion potential of cells. | 08-27-2009 |
20110150881 | INHIBITORS OF EXTRACELLULAR HSP90 - The present invention describes inhibitors of extracellular Hsp90. The inhibition of extracellular Hsp90 leads to a reduction of the invasiveness of the tumor cells. Furthermore, the invention relates to the use of molecules inhibiting extracellular Hsp90 function for the manufacture of a medicament for the treatment or prevention of invasion and/or metastatic potential of cancer cells. | 06-23-2011 |
20120058117 | NEUROPILIN-1 INHIBITORS - The present invention relates to molecules interfering with the function of neuropilin-1 in the context of angiogenesis and the treatment of cancer. Molecules, polypeptides, antibodies, compositions and methods are provided that are useful for reducing, inhibiting or treating angiogenesis, the invasion of blood vessels into tumors, and/or the invasion or the metastatic potential of specific tumor cells. Additionally, a method is provided that allows identifying molecules, which interfere with the functionality of neuropilin-1. Furthermore, a method is provided that allows determining whether a naturally occurring tumor cell depends on functional neuropilin-1 for its invasiveness and/or metastatic potential. | 03-08-2012 |
20130216536 | INHIBITORS OF EXTRACELLULAR HSP90 - The present invention describes inhibitors of extracellular Hsp90. The inhibition of extracellular Hsp90 leads to a reduction of the invasiveness of the tumor cells. Furthermore, the invention relates to the use of molecules inhibiting extracellular Hsp90 function for the manufacture of a medicament for the treatment or prevention of invasion and/or metastatic potential of cancer cells. | 08-22-2013 |
20140079720 | INHIBITORS OF EXTRACELLULAR HSP90 - The present invention describes inhibitors of extracellular Hsp90. The inhibition of extracellular Hsp90 leads to a reduction of the invasiveness of the tumor cells. Furthermore, the invention relates to the use of molecules inhibiting extracellular Hsp90 function for the manufacture of a medicament for the treatment or prevention of invasion and/or metastatic potential of cancer cells. | 03-20-2014 |
Patent application number | Description | Published |
20080272266 | High capacity work table having K-shaped legs for improved stability - A work table is provided having a table top and a pair of K-shaped leg supports. The K-shaped leg supports are attached to left and right underside portions of the table top. The K-shaped leg supports each include a vertical back leg, an upper front leg, and a lower front leg formed in the shape of a K. The upper front leg extends rearwardly and downwardly toward the back leg and is attached to one or both of the back leg or a rearward portion of the lower front leg. The lower front leg extends from a forward end rearwardly and upwardly and is attached at its rearward end to one or both of the back leg and a rearward portion of the upper front leg. The front edge of the lower front leg preferably extends forwardly slightly beyond the front edge of the table top. | 11-06-2008 |
20080272676 | Boltless cabinet assembly - A boltless panel assembly for use in constructing a boltless cabinet comprises a panel having exterior and interior faces and side edge portions. At least one slot engaging member is attached to and extends interiorly from each side edge portion of the panel for insertion into slots of boltless support post. A releasable retaining member prevents disengagement of the slot engaging member from a slot once it has been inserted into and seated in a slot of a boltless support post. | 11-06-2008 |
20090220704 | POWDER COATING SYSTEM FOR MDF PANELS - The present invention provides a process for powder coating shelving panels made of MDF or other particle board materials, peg board panels and other articles made of MDF, peg board or other wood-based products. The process comprises first mounting of the panel on a hanger assembly attachable to an overhead conveyor. The panel is passed through a preheat oven having a temperature of preferably from about 260° F. to about 280° F. for a period of from about 15 minutes to about 30 minutes. The preheated panel preferably having a surface temperature preferably of about 110° F. to 112° F. is then carried through a powder coating booth on a preferred hanger assembly where electrostatically charged particles are sprayed onto the surfaces of the panel. | 09-03-2009 |
20090277854 | MODULAR RACK ASSEMBLY - An end support unit for supporting the ends of at least one front and one rear cross beam including: a front support post having a column of slots along its length for receiving at least one slot engaging member of the front cross beam; a rear support post having a column of slots along its length for receiving at least one slot engaging member of the rear cross beam; an upper brace fixedly extending from the upper end of the front support post to the upper end of the rear support post; a lower brace fixedly extending from the lower end of the front support post to the lower end of the rear support post; and a diagonal brace extending diagonally between the front support post and the rear support post. | 11-12-2009 |
20090278004 | LOFT STORAGE RACK - A ceiling storage unit including: at least four brackets attachable to a ceiling; at least four support posts, each support post attachable to a bracket; a frame comprising at least two cross-beams attachable at their ends to the support posts; a shelf panel positioned on and supported by the frame; and at least two braces, each brace attachable at its ends to at least two support posts for supporting long items to be stored, wherein the positions of the braces and the frame along the support posts are adjustable. | 11-12-2009 |
20100084354 | REDUCED WEIGHT STORAGE RACK - A lightweight cross-beam for a storage rack made of a single sheet of steel with a Z-style cross sectional configuration includes a generally vertical upper wall with upper and lower edges; a generally horizontal support wall extending inwardly from the lower edge of the upper wall; an angled intermediate wall extending downwardly and outwardly from the inner edge of the generally horizontal wall; and a generally vertical lower wall that extends downwardly from the outer edge of the angled wall. The angle between the generally horizontal support wall and the angled wall is about 60°. The upper and lower walls are generally in the same vertical plane. Upper and lower rivets extend outwardly from the upper and lower walls at each end of the cross-beam. The vertical distance between the upper and lower rivets is 3 inches. The length of the cross-beam is at least about 96 inches. | 04-08-2010 |
20120125872 | MODULAR RACK ASSEMBLY - An end support unit for supporting the ends of at least one front and one rear cross beam including: a front support post having a column of slots along its length for receiving at least one slot engaging member of the front cross beam; a rear support post having a column of slots along its length for receiving at least one slot engaging member of the rear cross beam; an upper brace fixedly extending from the upper end of the front support post to the upper end of the rear support post; a lower brace fixedly extending from the lower end of the front support post to the lower end of the rear support post; and a diagonal brace extending diagonally between the front support post and the rear support post. | 05-24-2012 |
20160076733 | LED SOFT LIGHT - An improved LED soft light is disclosed, which comprises a trough assembly; a plurality of LED light assemblies housed within the trough assembly, each of the LED light assemblies comprising one or more LEDs to emit light and an Primary reflector surrounding the one or more LEDs to direct the light emitted by the one or more LEDs; and a secondary reflector positioned proximate a rear portion of the trough assembly to reflect the light emitted by the plurality of LED light assemblies and direct the emitted light out of the front of the soft light. | 03-17-2016 |
Patent application number | Description | Published |
20120124413 | METHOD AND SYSTEM FOR NETWORK ELEMENT SERVICE RECOVERY - A method and system for network element recovery are provided. In one form, frontend servers intelligently proxy error or unavailability messages returned by backend servers and simulate frontend server failure. In at least one form, the frontend server also includes intelligence or logic to determine that directing the client to recover service to an alternate system or site would assure better service availability, reliability, and/or quality-of-experience for the client. | 05-17-2012 |
20120124431 | METHOD AND SYSTEM FOR CLIENT RECOVERY STRATEGY IN A REDUNDANT SERVER CONFIGURATION - A method and system for client recovery strategy to maximize service availability for redundant configurations is provided. The technique includes adaptively adjusting timing parameter(s), detecting failures based on adaptively-adjusted timing parameter(s), and switching over to a redundant server. The timing parameter(s) include a maximum number of retries, response timers, and keepalive messages. Switching over to alternate servers engaged in warm sessions with the client may also be implemented to improve performance. The method and system allow for improved recovery time and suitable shaping of traffic to redundant servers. | 05-17-2012 |
20130212422 | Method And Apparatus For Rapid Disaster Recovery Preparation In A Cloud Network - Various embodiments provide a method and apparatus of providing a rapid disaster recovery preparation in cloud networks that proactively detects disaster events and rapidly allocates cloud resources. Rapid disaster recovery preparation may shorten the recovery time objective (RTO) by proactively growing capacity on the recovery application(s)/resource(s) before the surge of recovery traffic hits the recovery application(s)/resource(s). Furthermore, rapid disaster recovery preparation may shorten RTO by growing capacity more rapidly than during “normal operation” where the capacity is increased by modest growth after the load has exceeded a utilization threshold for a period of time. | 08-15-2013 |
20140215272 | PREVENTING EXTREME CORESIDENCY HAZARDS IN CLOUD COMPUTING - Various exemplary embodiments relate to a method of preventing extreme coresidency hazards among application instances in a cloud network. The method includes determining a first failure group of a first instance of an application; establishing a connection with a second instance of a peer application; determining a second failure group of the second instance; comparing the first failure group to the second failure group; and establishing a second connection with a third instance of the peer application if the first failure group and the second failure group share a failure point. | 07-31-2014 |
20150089275 | PREVENTING EXTREME CORESIDENCY HAZARDS IN CLOUD COMPUTING - Various exemplary embodiments relate to a method of preventing extreme coresidency hazards among application instances in a cloud network. The method includes determining a first failure group of a first instance of an application; establishing a connection with a second instance of a peer application; determining a second failure group of the second instance; comparing the first failure group to the second failure group; and establishing a second connection with a third instance of the peer application if the first failure group and the second failure group share a failure point. | 03-26-2015 |
Patent application number | Description | Published |
20110191366 | RULES-BASED TARGETED CONTENT MESSAGE SERVING SYSTEMS AND METHODS - A method of serving targeted content messages for display in a website accessed in a browser program of a networked computer communicatively connected to a network at a network address for communications, delivers uniquely targeted content messages displayed in websites viewed in web browsers. The method includes placing a script device in a website file, processing the website file, together with the script device by a particular web browser on download of the website file, including by determining the network address of the networked computer, determining an identifier of the website file, and sending an artifact representing the network address and the identifier over the network to a server computer. The method also includes detecting the network address and the identifier by the server computer, querying a database for a database article related to the network address and the identifier, constructing a script program stored in memory of the server computer for the particular browser and website file, and constructing an ad device stored in memory of the web browser device from the script program. The method further includes calling the server computer by the ad device by communication of an identifier representing an action of the web browser device, receiving the identifier by the server computer, querying the database for a select message artifact related to the script program, the identifier, the website file, and the web browser, and responding by the server computer to the web browser with the select message artifact. A message represented by the select message artifact is displayed in the website then viewed in a browser window of the web browser. Messages can be prioritized and are uniquely targeted in content, based on real-time activities of the web browser. | 08-04-2011 |
20150073917 | Rules-Based Targeted Content Message Serving Systems and Methods - A method of serving targeted content messages for display in a website accessed in a browser program of a networked computer communicatively connected to a network at a network address for communications, delivers uniquely targeted content messages displayed in websites viewed in web browsers. The method includes placing a script device in a website file, processing the website file, together with the script device by a particular web browser on download of the website file, including by determining the network address of the networked computer, determining an identifier of the website file, and sending an artifact representing the network address and the identifier over the network to a server computer. The method also includes detecting the network address and the identifier by the server computer, querying a database for a database article related to the network address and the identifier, constructing a script program stored in memory of the server computer for the particular browser and website file, and constructing an ad device stored in memory of the web browser device from the script program. The method further includes calling the server computer by the ad device by communication of an identifier representing an action of the web browser device, receiving the identifier by the server computer, querying the database for a select message artifact related to the script program, the identifier, the website file, and the web browser, and responding by the server computer to the web browser with the select message artifact. A message represented by the select message artifact is displayed in the website then viewed in a browser window of the web browser. Messages can be prioritized and are uniquely targeted in content, based on real-time activities of the web browser. | 03-12-2015 |
20150227983 | SEGMENT CONTENT OPTIMIZATION DELIVERY SYSTEM AND METHOD - A method for identifying segments of a population of user devices communicating on a communications network. The segments correspond to user devices of the population exhibiting comparable behavioral patterns detectable by the communications network. A plurality of marketing systems are accessible on the communications network, and each of the plurality of marketing systems include respective use data corresponding to respective ones of the population for the marketing system. The method includes retrieving by a processor the respective use data for the population, from the plurality of marketing systems, determining by the processor if the respective use data exceeds a threshold for particular behavioral pattern of interest, for the respective use data, determining by the processor a unique identifier for each user device of the use data, grouping by the processor in a database, the respective use data in relation to the unique identifier, for each user device of the use data that exceeds the threshold, and mapping by the processor in the database, the behavioral pattern of the respective use data for each user device of the use data that exceeds the threshold. Behavioral patterns are determined for the respective segment, and related to the user devices of the segment. Content for delivery to the segment is sequenced, and placeholder in the sequence is stored in relation to each user device of the segment, to ensure that each next sequential content is delivered to the respective user device. | 08-13-2015 |