Patent application number | Description | Published |
20100292569 | SYSTEMS AND METHODS FOR DYNAMIC IMAGING OF TISSUE USING DIGITAL OPTICAL TOMOGRAPHY - A methods for imaging tissue using diffuse optical tomography with digital detection includes directing at the tissue a plurality of amplitude modulated optical signals from a plurality of optical signal sources illuminating the tissue at a plurality of locations; detecting a resulting plurality of attenuated optical signals exiting the tissue to obtain a plurality of analog signals containing diffuse optical tomographic information; converting the analog signals into digital signals; recovering the tomographic information from the digital signals using a digital signal processor-based detection module that performs digital detection, wherein the detection module includes a master digital signal processing subsystem and at least one slave digital signal processing subsystem that processes at least a portion of the digital signals and the master digital signal processing subsystem controls the at least one slave digital signal processing subsystem; and transmitting the recovered tomographic information in digital form to a host computer. | 11-18-2010 |
20130289394 | DYNAMIC OPTICAL TOMOGRAPHIC IMAGING DEVICES METHODS AND SYSTEMS - The disclosed subject matter includes optical tomographic systems for acquiring and displaying dynamic data representing changes in a target tissue sample to external provocation. For example, the disclosed devices, methods and systems may be used for quantifying dynamic vascular changes caused by imposed blood pressure changes for diagnosing peripheral artery disease. | 10-31-2013 |
20130338496 | MEDICAL IMAGING DEVICES, METHODS, AND SYSTEMS - Devices, methods, and systems for providing optical imaging to detect and characterize anatomical and/or physiological indicators, such as, rheumatoid arthritis, and devices, methods and systems for computer aided detection and diagnosis of tomographic images. Embodiments for optimizing machine classification of tissue samples are described. Embodiments for using machine classification techniques to classify indicators present in optical tomographic images are described. | 12-19-2013 |
20140088415 | MEDICAL IMAGING DEVICES, METHODS, AND SYSTEMS - The disclosed subject matter includes devices, methods, and systems for generating optical tomographic data including volumetric and surface geometric data. The disclosed subject matter also includes devices, methods, and systems for generating optical tomographic data for purposes of diagnosing rheumatoid arthritis. | 03-27-2014 |
20140236003 | INTERFACING SYSTEMS, DEVICES, AND METHODS FOR OPTICAL IMAGING - An imaging interface for diffuse optical tomography of breast includes a plurality of concentric rings. Each concentric ring can include a plurality of optical input/output apertures arranged on a radially inner surface thereof. The rings can have different inner and outer diameters from each other and can be arranged in a stacked configuration. The rings can translate independently of each other along a central axis of the stack. During imaging the breast is inserted into an inner region of the stacked rings. The rings can be translated such that the optical input/output apertures are brought into touch contact (i.e., non-compressing contact) with the surface of the breast, so as to accommodate different size breasts. The rings may be translated such that the spacing between adjacent rings is increased for large breasts and reduced for smaller breasts. Rings may be removed or additional rings added to further accommodate additional breast sizes. | 08-21-2014 |
20140243681 | COMPACT OPTICAL IMAGING DEVICES, SYSTEMS, AND METHODS - An optical imaging device and system can be used to visualize and/or provide a quantitative measure of changes in patient vasculature, for example, to monitor responsiveness of a tumor to a particular chemotherapy treatment. A plurality of detectors (e.g., two) are spaced from a plurality of substantially monochromatic light sources (e.g., four) on an interrogation face of the handheld device. Wavelengths of light in the near-infrared range are used to measure the content of hemoglobin, water, and lipid of the tissue that the interrogation face comes in contact with. The light can be modulated so that the effect of ambient light is not minimized or at least reduced. The detected signal is amplified, filtered, and digitized within the device by appropriate electronics. In embodiments, handheld device can include a wireless communication module, such as a Bluetooth device, for wireless transmission of data to/from the remote processor or computer. | 08-28-2014 |
20140313305 | TOMOGRAPHIC IMAGING METHODS, DEVICES, AND SYSTEMS - A multispectral bioluminescence optical tomography algorithm makes use of a partial differential equation (PDE) constrained approach. A sequential quadratic programming (SQP) method is demonstrated that allows for solving both forward and inverse problems at once by updating the forward and inverse variables simultaneously at each step of the optimization iterations. Light propagation in biological tissue is modeled by using the equation of radiative transfer (ERT) and performance of the ERT-based PDE-constrained approach is modeled through numerical and experimental studies. | 10-23-2014 |
20140330116 | SYSTEMS AND METHODS FOR SIMULTANEOUS MULTI-DIRECTIONAL IMAGING FOR CAPTURING TOMOGRAPHIC DATA - Devices, systems, and method for tomographic imaging are described in which light transmitted and backscattered surface light is imaged by an optical system that minimizes reflection back to the target object while providing the ability to direct surface image rays to a single imaging device. In an embodiment, a curved reflector surrounds, fully or partly, a target object but is angled to reflect light toward the imaging camera. | 11-06-2014 |