Qin, MA
Albert Qin, Winchester, MA US
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20110097345 | NOVEL DOSING REGIMEN AND METHOD OF TREATMENT - This invention relates to a method of treatment and dosing regimen for treating disease, such as cancer and mammalian tumors, wherein therapy with a cytotoxic drug is suitable, by the administration of an antibody-toxin conjugate, such as a maytansinoid toxin, by infusion at an initial infusion rate of 1 mg/min or lower on a schedule selected from the group consisting of: (1) an amount of at least about 90 mg/m | 04-28-2011 |
Derek Yong Qin, Andover, MA US
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20140336948 | System and Method for Improving Signal to Noise Ratio for High Frequency Signal Component - An apparatus and method for improving signal to noise ratio of a physiological signal is provided. At least one sensor senses the analog data signal, the analog data signal having a first component including ECG data and a second component including ancillary data. A converter is coupled to the at least one sensor that automatically converts the analog data signal into a digital data signal and decimates the digital data signal from a first sample rate to a second sample rate. A gain compensation circuit is coupled to the converter that automatically measures a magnitude of at least one of the first component and second component of the digital data signal and compares the measured magnitude to a reference value to determine if a gain applied to the analog data signal should be modified and automatically compensates the digital data signal in response to the determination that the analog gain value should be modified, wherein the compensated digital data signal corrects defects associated with a settling period of the converter resulting from modifying the gain applied to the analog data signal. | 11-13-2014 |
Gangjian Qin, Boston, MA US
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20100130414 | Methods of Using E2F2 for the Treatment of Hypertension - The present invention features compositions and methods of treating or preventing hypertension or a cardiac indication. In particular embodiments, the invention provides E2F2 as a new therapeutic target for the treatment of hypertension or a cardiac indication, and methods of increasing the expression and/or activity of E2F2. | 05-27-2010 |
Lei Qin, Natick, MA US
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20110201916 | MOVEMENT CORRECTION IN MRI USING A CAMERA - Provided are methods and systems for movement correction in an MRI environment. In one aspect, provided are systems and methods for movement correction, comprising receiving a first plurality of images from a first scan of a subject with a first camera, receiving magnetic resonance imaging (MRI) images obtained concurrently with the first scan, correlating the first plurality of images obtained from the first scan with the MRI images, resulting in motion correction data, and providing the motion correction data to an MRI system, wherein the MRI system adjusts scanning according to the motion correction data. | 08-18-2011 |
Shan Qin, Brighton, MA US
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20110020326 | METHOD OF TREATING POLYCYSTIC KIDNEY DISEASE - The present invention is directed toward methods for treating, inhibiting the progression of or eradicating polycystic kidney disease in a mammal in need thereof by providing a cMET inhibitor. | 01-27-2011 |
Shuzhen Qin, West Roxbury, MA US
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20090075305 | Diagnostic serum antibody profiling - The invention is directed to a microarray assay procedure that can be used for profiling the antibodies present in serum, plasma or blood. The assay may be used to identify antibodies and antigens that are characteristic of particular diseases or conditions. In addition, the invention includes specific antigens that are associated with prostate cancer, progressive benign prostate hyperplasia (BPH) and ovarian cancer. | 03-19-2009 |
20100280032 | METHOD FOR TREATING INFLAMMATORY DISORDERS - The present invention relates to a method for suppressing the immune system in a subject in need thereof, and a method for treating an inflammatory or immune disorder in a subject in need thereof. | 11-04-2010 |
20100298331 | TRIAZINONE AND DIAZINONE DERIVATIVES USEFUL AS HSP90 INHIBITORS - The present invention relates to compounds according to formulae (IA) to (ID) and compositions that inhibit the activity of Hsp90. The invention further relates to methods of inhibiting the activity of Hsp90 in a subject in need thereof and methods for preventing or treating hyperproliferative disorders, such as cancer, in a subject in need thereof comprising administering to the subject a compound of the invention, or a composition comprising such a compound. | 11-25-2010 |
20110319447 | TRIAZOLE COMPOUNDS THAT MODULATE HSP90 ACTIVITY - The present invention relates to substituted triazole compounds and compositions comprising substituted triazole compounds. The invention further relates to methods of inhibiting the activity of Hsp90 in a subject in need thereof and methods for preventing or treating hyperproliferative disorders, such as cancer, in a subject in need thereof comprising administering to the subject a substituted triazole compound of the invention, or a composition comprising such a compound. | 12-29-2011 |
20120122869 | TRIZAOLE COMPOUNDS THAT MODULATE HSP90 ACTIVITY - The present invention relates to substituted triazole compounds and compositions comprising substituted triazole compounds. The invention further relates to methods of inhibiting the activity of Hsp90 in a subject in need thereof and methods for preventing or treating hyperproliferative disorders, such as cancer, in a subject in need thereof comprising administering to the subject a substituted triazole compound of the invention, or a composition comprising such a compound. | 05-17-2012 |
20120202813 | TRIAZOLE COMPOUNDS THAT MODULATE HSP90 ACTIVITY - The present invention relates to substituted triazole compounds and compositions comprising substituted triazole compounds. The invention further relates to methods of inhibiting the activity of Hsp90 in a subject in need thereof and methods for preventing or treating hyperproliferative disorders, such as cancer, in a subject in need thereof comprising administering to the subject a substituted triazole compound of the invention, or a composition comprising such a compound. | 08-09-2012 |
20130072461 | TRIAZOLE COMPOUNDS THAT MODULATE HSP90 ACTIVITY - The present invention relates to substituted triazole compounds and compositions comprising substituted triazole compounds. The invention further relates to methods of inhibiting the activity of Hsp90 in a subject in need thereof and methods for preventing or treating hyperproliferative disorders, such as cancer, in a subject in need thereof comprising administering to the subject a substituted triazole compound of the invention, or a composition comprising such a compound. | 03-21-2013 |
20130296378 | TRIAZOLE COMPOUNDS THAT MODULATE HSP90 ACTIVITY - The present invention relates to substituted triazole compounds and compositions comprising substituted triazole compounds. The invention further relates to methods of inhibiting the activity of Hsp90 in a subject in need thereof and methods for preventing or treating hyperproliferative disorders, such as cancer, in a subject in need thereof comprising administering to the subject a substituted triazole compound of the invention, or a composition comprising such a compound. | 11-07-2013 |
20130345219 | TRIAZINONE AND DIAZINONE DERIVATIVES USEFUL AS HSP90 INHIBITORS - The present invention relates to compounds according to formulae (IA) to (ID) and compositions that inhibit the activity of Hsp90. The invention further relates to methods of inhibiting the activity of Hsp90 in a subject in need thereof and methods for preventing or treating hyperproliferative disorders, such as cancer, in a subject in need thereof comprising administering to the subject a compound of the invention, or a composition comprising such a compound. | 12-26-2013 |
20140141511 | METHOD FOR TREATING INFLAMMATORY DISORDERS - The present invention relates to a method for suppressing the immune system in a subject in need thereof, and a method for treating an inflammatory or immune disorder in a subject in need thereof. | 05-22-2014 |
20140371222 | TRIAZOLE COMPOUNDS THAT MODULATE HSP90 ACTIVITY - The present invention relates to substituted triazole compounds and compositions comprising substituted triazole compounds. The invention further relates to methods of inhibiting the activity of Hsp90 in a subject in need thereof and methods for preventing or treating hyperproliferative disorders, such as cancer, in a subject in need thereof comprising administering to the subject a substituted triazole compound of the invention, or a composition comprising such a compound. | 12-18-2014 |
Xiaojun Qin, Cambridge, MA US
Patent application number | Description | Published |
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20100324120 | LIPID FORMULATION - The invention features a cationic lipid of formula I, | 12-23-2010 |
20120101148 | LIPID FORMULATION - The invention features an improved lipid formulation comprising a cationic lipid of formula (A), a neutral lipid, a sterol and a PEG or PEG-modified lipid, where R | 04-26-2012 |
20120183602 | LIPID FORMULATION - The invention features a cationic lipid of formula I, | 07-19-2012 |
Xuebin Qin, Westwood, MA US
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20100111949 | METHODS AND COMPOSITIONS FOR THE TREATMENT OF PROLIFERATIVE DISEASES - The invention features peptides containing domain 4 of the | 05-06-2010 |
20100291024 | METHODS AND COMPOSITIONS FOR THE TREATMENT OF PROLIFERATIVE AND PATHOGENIC DISEASES - The invention features peptide fragments containing domain 4 of the | 11-18-2010 |
20120269801 | METHODS AND COMPOSITIONS FOR THE TREATMENT OF PROLIFERATIVE AND PATHOGENIC DISEASES - The invention features proteins including an antibody, or functional derivatives thereof, that bind hCD59 and have the activity of domain 4 of the | 10-25-2012 |
Yi Qin, Marlborough, MA US
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20130206602 | PLATING BATH AND METHOD - Tin-silver alloy electroplating baths having certain amine-oxide surfactants and methods of electrodepositing a tin-silver-containing layer using these baths are disclosed. Such electroplating baths are useful to provide tin-silver solder deposits having reduced void formation and improved within-die uniformity. | 08-15-2013 |
20140353162 | ELECTROPLATING BATHS OF SILVER AND TIN ALLOYS - Silver and tin alloy electroplating baths include complexing agents which enable the electroplating of either silver rich or tin rich alloys. The silver and tin alloy electroplating baths are substantially free of lead. They may be used to electroplate silver and tin alloys in the manufacture of electronic components such as electrical connectors, finishing layers for metallic substrates, decorative applications and solder bumps. | 12-04-2014 |
Yi Qin, Westborough, MA US
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20150122661 | PLATING BATH AND METHOD - Tin-containing electroplating baths having a combination of certain brightening agents provide tin-containing solder deposits having reduced void formation and smooth morphology. | 05-07-2015 |
20150122662 | PLATING BATH AND METHOD - Tin electroplating baths having certain brightening agents and nonionic surfactants provide tin-containing solder deposits having good morphology, reduced void formation and improved within-die uniformity. | 05-07-2015 |
Zheng-Hong Qin, Wilmington, MA US
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20090209468 | Alpha-neurotoxin proteins with anti-inflammatory properties and uses thereof - The invention provides methods and compositions for treating arthritic conditions such as osteoporosis and rheumatoid arthritis. The treatment methods include administering an effective amount of a pharmaceutical composition comprising an isolated alpha-neurotoxin protein, or an effective variant or fragment thereof. The compositions are effective for decreasing the levels of pro-inflammatory cytokines and increasing the level of interleukin-10 in a subject with arthritis, and can reduce symptoms of the arthritic condition including edema, infiltration of inflammatory cells and pannus formation in affected joints. In some preferred embodiments of compositions in accordance with the invention, the effective therapeutic protein is an alpha-neurotoxin protein isolated from snake venom, or a recombinant or synthetic protein based on, or derived from, the amino acid of sequence of an alpha-neurotoxin protein isolated from snake venom. Some preferred alpha-neurotoxin proteins are derived from the venom of elapid snakes including | 08-20-2009 |