Haupts
Marcel Haupts, Stolberg DE
Patent application number | Description | Published |
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20090004267 | Dosage Form with Impeded Abuse - A multiparticulate dosage form formulated to make misuse more difficult containing least one active substance with potential for misuse (A), at least one synthetic or natural polymer (C), optionally at least one natural, semi-synthetic or synthetic wax (D), at least one disintegrant (E) and optionally one or more additional physiologically compatible excipients (B), wherein the individual particles of the dosage form display a breaking strength of at least 500 N and a release of active substance of at least 75% after 45 minutes measured according to Ph.Eur. in the paddle mixer with sinker in 600 ml of aqueous buffer solution with a pH value of 1.2 at 37° C. and 75 rpm. | 01-01-2009 |
20110187017 | PREPARATION OF A POWDERY PHARMACEUTICAL COMPOSITION BY MEANS OF AN EXTRUDER - The invention relates to a method for the preparation of a powdery pharmaceutical composition comprising a pharmaceutical excipient and a pharmaceutical component, the method comprising the step of extruding a mixture of the pharmaceutical excipient and the pharmaceutical component in an extruder at a temperature profile allowing a liquid melt of the mixture to congeal in the extruder and to exit the extruder in form of a powder. | 08-04-2011 |
20130028970 | Tamper-resistant tablet providing immediate drug release - The invention relates to a tamper-resistant tablet comprising | 01-31-2013 |
20130028972 | Tamper-resistant tablet providing immediate drug release - The invention relates to a tamper-resistant tablet comprising | 01-31-2013 |
Ulrich Haupts, Odenthal DE
Patent application number | Description | Published |
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20100297700 | Antibodies to TNF Alpha - Provided herein are antibodies, antigen binding portions, and derivatives thereof that are capable of binding tumor necrosis factor alpha (TNFα); nucleic acids encoding the antibodies, antigen binding portions, and derivatives thereof, including complementary nucleic acids; vectors; and host cells containing the nucleic acids. | 11-25-2010 |
20120237496 | PROTEASE VARIANTS - The present invention relates to polypeptides comprising protease variants of wild type human neprilysin having an altered specificity and/or activity. In particular the present invention relates to polypeptides comprising protease variants derived from human neprilysin having an increased specificity and/or activity against certain substrates, in particular against amyloid beta. | 09-20-2012 |
20130230886 | Antibodies to TNF Alpha - Provided herein are antibodies, antigen binding portions, and derivatives thereof that are capable of binding tumor necrosis factor alpha (TNFα); nucleic acids encoding the antibodies, antigen binding portions, and derivatives thereof, including complementary nucleic acids; vectors; and host cells containing the nucleic acids. | 09-05-2013 |
20140148390 | FUSION PROTEINS RELEASING RELAXIN AND USES THEREOF - The present invention provides Relaxin fusion proteins, wherein a linker connects the carboxy-terminus of Relaxin with a proteinaceous half-life extending moiety and the linker comprises a protease cleavage site. Therefore, the invention provides Relaxin fusion polypeptides with extended half-life whereby the fusion protein by itself serves as a depot for release of the biologically active Relaxin. Furthermore, the invention provides nucleic acid sequences encoding the foregoing fusion polypeptides, vectors containing the same, cells expressing the Relaxin fusion polypeptides, pharmaceutical compositions and medical use of such fusion polypeptides. | 05-29-2014 |
20140187491 | RELAXIN FUSION POLYPEPTIDES AND USES THEREOF - The present invention provides Relaxin fusion polypeptides A-L-B with a non-wild type array of the Relaxin A-chain and Relaxin B-chain, wherein the A- and B-chains are connected by a linker peptide. The invention further provides Relaxin fusion polypeptides with extended half-life. Furthermore, the invention provides nucleic acid sequences encoding the foregoing fusion polypeptides, vectors containing the same, pharmaceutical compositions and medical use of such fusion polypeptides. | 07-03-2014 |
Ulrich Haupts, Koln DE
Patent application number | Description | Published |
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20090208440 | BIOLOGICAL ENTITIES AND THE USE THEREOF - The present invention provides engineered enzymes generated from protein scaffolds combined with Specificity Determining Regions, the production thereof and the use of said engineered enzymes for research, nutritional care, personal care and industrial purposes. | 08-20-2009 |
Ulrich Haupts, Nattermannallee DE
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20090208474 | BIOLOGICAL ENTITIES AND THE USE THEREOF - The present invention provides engineered enzymes generated from protein scaffolds combined with Specificity Determining Regions, the production thereof and the use of said engineered enzymes for research, nutritional care, personal care and industrial purposes. | 08-20-2009 |
Volker Haupts, Aachen DE
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20130255602 | FLEXIBLE HEAT ACCUMULATOR FOR ENGINE COOLANT - A heat accumulator for a vehicle engine, comprising storing coolant in a flexible storage container with an inner body and an outer body, with an insulation device arranged between the bodies, and an inflow and an outflow for the coolant wherein the storage container can expand and deflate in response to the amount of coolant stored. The flexible storage container allows for the heat accumulator to conform to various under hood space constraints. | 10-03-2013 |