Patent application number | Description | Published |
20090220943 | HCV GENOTYPING AND PHENOTYPING - The present invention includes methods of genotyping and phenotyping HCV. In one embodiment, the methods of the invention can be used to determine whether a HCV isolate is resistant to an antiviral drug. The invention also includes primers for amplifying a HCV NS3 region and kits. | 09-03-2009 |
20100099851 | SYNTHETIC HYPERGLYCOSYLATED, PROTEASE-RESISTANT POLYPEPTIDE VARIANTS, ORAL FORMULATIONS AND METHODS OF USING THE SAME - The present invention provides synthetic Type I interferon receptor polypeptide agonists comprising consensus or hybrid Type I interferon receptor polypeptide agonists, containing one or more native or non-native glycosylation sites. The present invention further provides oral formulations of protease-resistant or protease-resistant, hyperglycosylated polypeptide variants, which polypeptide variants lack at least one protease cleavage site found in a parent polypeptide, and thus exhibit increased protease resistance compared to the parent polypeptide, which polypeptide variants further include (1) a carbohydrate moiety covalently linked to at least one non-native glycosylation site not found in the parent protein therapeutic or (2) a carbohydrate moiety covalently linked to at least one native glycosylation site found but not glycosylated in the parent protein therapeutic. The present invention further provides compositions, including oral pharmaceutical compositions, comprising the synthetic Type I interferon receptor polypeptide agonist, the hyperglycosylated polypeptide variant, the protease-resistant polypeptide variant, or the hyperglycosylated, protease-resistant polypeptide variant. The present invention further provides containers, devices, and kits comprising the synthetic Type I interferon receptor polypeptide agonist, the hyperglycosylated polypeptide variant, the protease-resistant polypeptide variant, or the hyperglycosylated, protease-resistant polypeptide variant. The present invention further provides therapeutic methods involving administering an effective amount of an oral pharmaceutical composition comprising a synthetic Type I interferon receptor polypeptide agonist, a hyperglycosylated polypeptide variant, a protease-resistant polypeptide variant, or a hyperglycosylated, protease-resistant polypeptide variant to an individual in need thereof. | 04-22-2010 |
20110008289 | HYPERGLYCOSYLATED POLYPEPTIDE VARIANTS AND METHODS OF USE - The present invention provides synthetic Type I interferon receptor polypeptide agonists comprising consensus or hybrid Type I interferon receptor polypeptide agonists, containing one or more native or non-native glycosylation sites. The present invention provides synthetic Type I interferon receptor polypeptide agonists comprising consensus or hybrid Type I interferon receptor polypeptide agonists, containing one or more native or non-native glycosylation sites, as well as erythropoietin and darbepoetin alfa, each of which are linked to a penetrating peptide that facilitates translocation of a substance across a biological barrier as well as pharmaceutical compositions, including oral formulations, of the same. The present invention further provides oral formulations of hyperglycosylated or protease-resistant, hyperglycosylated polypeptide variants, which polypeptide variants lack at least one protease cleavage site found in a parent polypeptide, and thus exhibit increased protease resistance compared to the parent polypeptide, which polypeptide variants further include (1) a carbohydrate moiety covalently linked to at least one non-native glycosylation site not found in the parent protein therapeutic or (2) a carbohydrate moiety covalently linked to at least one native glycosylation site found but not glycosylated in the parent protein therapeutic. The present invention further provides compositions, including oral pharmaceutical compositions, comprising the synthetic Type I interferon receptor polypeptide agonist, the hyperglycosylated polypeptide variant, or the hyperglycosylated, protease-resistant polypeptide variant. The present invention further provides containers, devices, and kits comprising the synthetic Type I interferon receptor polypeptide agonist, the hyperglycosylated polypeptide variant, or the hyperglycosylated, protease-resistant polypeptide variant. The present invention further provides therapeutic methods involving administering an effective amount of an oral pharmaceutical composition comprising a synthetic Type I interferon receptor polypeptide agonist, a hyperglycosylated polypeptide variant, or a hyperglycosylated, protease-resistant polypeptide variant to an individual in need thereof. | 01-13-2011 |
Patent application number | Description | Published |
20090205710 | Thin film type solar cell and method for manufacturing the same - A thin film type solar cell and a method for manufacturing the same is disclosed, which is capable of realizing the improved efficiency in the solar cell with a decreased dead zone, wherein the method comprises forming a plurality of front electrodes on a substrate, wherein the plurality of front electrodes are formed at fixed intervals by each first separating portion interposed in-between; forming a semiconductor layer and transparent conductive layer on an entire surface of the substrate including the front electrodes; forming a contact portion being in contact with the first separating portion by removing predetermined portions of the semiconductor layer and transparent conductive layer; forming a second separating portion by removing a predetermined portion of the transparent conductive layer; and forming a rear electrode connected with the front electrode through the contact portion. | 08-20-2009 |
20090308449 | Thin film type solar cell and method for manufacturing the same - A thin film type solar cell and a method for manufacturing the same is disclosed, wherein the thin film type solar cell includes a first anti-oxidation layer formed on a front electrode, and a semiconductor layer formed on the first anti-oxidation layer, so that it is possible to prevent an oxide from being formed in the interface between the front electrode and the semiconductor layer by preventing a reaction between an oxidant contained in the front electrode and silicon of the semiconductor layer, to thereby realize improved cell efficiency, wherein the method for manufacturing the thin film type solar cell comprises forming the front electrode on a substrate; forming the first anti-oxidation layer on the front electrode; forming the semiconductor layer on the first anti-oxidation layer; and forming a rear electrode on the semiconductor layer. | 12-17-2009 |
20130118577 | Thin Film Type Solar Cell and Method for Manufacturing the Same - A thin film type solar cell and a method for manufacturing the same is disclosed, wherein the thin film type solar cell includes a first anti-oxidation layer formed on a front electrode, and a semiconductor layer formed on the first anti-oxidation layer, so that it is possible to prevent an oxide from being formed in the interface between the front electrode and the semiconductor layer by preventing a reaction between an oxidant contained in the front electrode and silicon of the semiconductor layer, to thereby realize improved cell efficiency, wherein the method for manufacturing the thin film type solar cell comprises forming the front electrode on a substrate; forming the first anti-oxidation layer on the front electrode; forming the semiconductor layer on the first anti-oxidation layer; and forming a rear electrode on the semiconductor layer. | 05-16-2013 |
20130143349 | SOLAR CELL AND METHOD OF MANUFACTURING THE SAME - In one embodiment, a method of manufacturing a solar cell includes forming a first electrode over a substrate; forming a light-converting layer over the first electrode and patterning the light-converting layer to form a plurality of patterned light-converting layers that are spaced apart from each other; forming a transparent insulating layer over the first electrode including the patterned light-converting layers; and forming a second electrode over the transparent insulating layer. | 06-06-2013 |
Patent application number | Description | Published |
20090047025 | Multiple Electrical Level Dispersion Tolerant Optical Apparatus - An optical apparatus consisting of a transmitter, receiver, or transceiver, utilizing a multiple level special electrical layer modulation and/or demodulation scheme to significantly lower the bandwidth required for high speed communication and/or parallel interconnect systems. It can be used either to enhance the transmission performance of the transceiver, or to eliminate the need for bulky and/or expensive optical components to lower the cost. It can be used in the design of transponders, transceivers, and active cabling systems, for 10 Gb/s, 40 Gb/s, 100 Gb/s and other high bit rate transmission systems that utilize single mode or multi-mode fibers for serial or parallel transmission of high speed optical signals. | 02-19-2009 |
20090150193 | Comprehensive Integrated Online Order and Reservation Platform with Instant Notifications and Interactive Communications - An fully integrated online ordering, online reservation and online catering platform, an advanced software system architecture, and a suite of new types of online services designed and suitable for various industries, especially for restaurant industry, providing business owners and Internet users with a comprehensive and reconfigurable sets of options to deliver and respond to online requests automatically and instantly through various means of real time interactive communications. | 06-11-2009 |
20090167553 | Open Mobile Online Reservation and Ordering Systems - The invention relates to a new “mobile and online based ordering and reservation system” by integrating, synchronizing and utilizing the capability of wireless devices, Internet servers, business web sites and service aggregation portals, to automate the mobile and online ordering and reservation processes in real time, and therefore offering a plural of new mobile and online services and applications. | 07-02-2009 |
20090304395 | Tunable Electrical Return-to-Zero Modulation Method and Apparatus - A tunable duty cycle electrical return-to-zero (RZ) modulation method is realized through tuning of some electrical parameters of an encoder without the need for expensive and/or bulky optical pulse carver, therefore providing a universal RZ apparatus suitable for various high speed applications such as at 10 Gb/s, 40 Gb/s and 100 Gb/s. The electrical RZ modulation scheme is readily combined with other known modulation technologies on the transmitter side to support low cost RZ modulation for metro, long haul and submarine systems. | 12-10-2009 |