Hajime Mizuno
Hajime Mizuno, Hiroshima-Shi JP
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20100317118 | CAPTURING OF CELL FLUID AND ANALYSIS OF ITS COMPONENTS UNDER OBSERVATION OF CELLS AND INSTRUMENTS FOR THE CELL FLUID CAPTURING AND THE ANALYSIS - The invention provide the method to enable the molecular detections of cellular fluid of at least a single cell easily and rapidly and clarify the dynamics of life phenomena and molecular mechanisms very rapidly by conducting simultaneous observations of cellular morphological dynamism. At the same time, it provides the method of exploring active molecules. Even in case that the target is a single cell, the cellular fluid is directly sucked by the capillary tip and the fluid is subjected to the analysis directly. By performing this method under the observation of the cell with image-magnifying scopes, such as a microscope, the cellular fluid is sucked and captured by the nanospray ionization capillary tip even if the target is a single cell and the trapped sample is subjected to the mass spectrometer by nano-spraying the sample solution directly after addition of the ionization supporting solvent into the tip, and then the molecular components in the cellular fluid is detected. The detected molecular peaks specific to a certain state are identified by performing differential analysis or t-test between the data groups of cells in different states. | 12-16-2010 |
20140315237 | CAPTURING OF CELL FLUID AND ANALYSIS OF ITS COMPONENTS UNDER OBSERVATION OF CELLS AND INSTRUMENTS FOR THE CELL FLUID CAPTURING AND THE ANALYSIS - A method captures cellular components from a single cell and performs mass spectrometry on the components. The method includes inserting a nanospray ionization capillary tip into a specific region of the cell under observation with a microscope. The nanospray ionization capillary tip can include a filament in the interior. The method further includes capturing the cellular components of the specific region of the cell into the opening of the nanospray ionization capillary tip and keeping the components at the nanospray ionization capillary tip, supplying an ionization supporting solvent from a back-end of the nanospray ionization capillary tip, applying an electric field between a sample inlet of a mass spectrometer and the nanospray ionization capillary tip, whereby nanospray ionization to the cellular components is implemented, and performing the mass spectrometry on the cellular components captured at the nanospray ionization capillary tip. | 10-23-2014 |
Hajime Mizuno, Toyonaka-Shi JP
Patent application number | Description | Published |
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20090203674 | PYRIMIDINE COMPOUND AND PESTS CONTROLLING COMPOSITION CONTAINING THE SAME - The present invention relates to a pyrimidine compound of the formula (I): | 08-13-2009 |
20090209518 | PYRIMIDINE COMPOUND AND PESTS CONTROLLING COMPOSITION CONTAINING THE SAME - The present invention relates to a pyrimidine compound of the formula (I): | 08-20-2009 |
20090209519 | PYRIMIDINE COMPOUND AND PESTS CONTROLLING COMPOSITION CONTAINING THE SAME - The present invention relates to a pyrimidine compound of the formula (I): | 08-20-2009 |
20100036117 | PYRIMIDINE COMPOUND AND PESTS CONTROLLING COMPOSITION CONTAINING THE SAME - The present invention relates to a pyrimidine compound of the formula (II′): | 02-11-2010 |
20120041009 | PYRIMIDINE COMPOUND AND ITS USE IN PEST CONTROL - A pyrimidine compound represented by below formula (I) has excellent control activity against pests and is useful as an active ingredient of a pest controlling agent. | 02-16-2012 |
20120088914 | PRODUCTION METHOD OF PYRIMIDINE COMPOUNDS - 4-amino-6-alkynyloxypyrimidine compounds shown by the formula (V) | 04-12-2012 |
Hajime Mizuno, Shanghai CN
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20090092268 | ELECTRONIC APPARATUS OF SPLITTABLE TYPE - The present invention discloses an electronic apparatus of splittable type comprising at least two speaker portions, the two speaker portions are connected by electro-wires, wherein in one speaker portion is provided a winding mechanism for pulling-out and retracting-in the electro-wires; each of the speaker portions has a voice chamber, and the voice chambers in the two speaker portions have the different shapes from but substantially the same volumes as each other. | 04-09-2009 |
Hajime Mizuno, Takarazuka-Shi JP
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20150094329 | FUSED HETEROCYCLIC COMPOUND - A compound represented by formula (1) and an N-oxide thereof have excellent pest control effect. (In the formula, Het to which R | 04-02-2015 |
20150189880 | AMIDE COMPOUND - A fused heterocyclic compound represented by formula (I) has an excellent pest control effect. In the formula, R | 07-09-2015 |
Hajime Mizuno, Takarazuka-Shi, Hyogo JP
Patent application number | Description | Published |
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20150336881 | AMIDE COMPOUND AND USE THEREOF FOR PEST CONTROL - A fused heterocyclic compound represented by formula (1) has an excellent pest control effect. | 11-26-2015 |
20150336895 | AMIDE COMPOUND AND USE THEREOF FOR PEST CONTROL - A fused heterocyclic compound represented by formula (1) has an excellent pest control effect. (In the formula, R | 11-26-2015 |