Patent application number | Description | Published |
20090017444 | Screening method for modulators of viral transcription or replication - The invention provides methods to identify modulators of viral transcription or replication. | 01-15-2009 |
20100021499 | CELL-BASED SYSTEMS FOR PRODUCING INFLUENZA VACCINES - The present invention relates to a cell-based method for producing influenza virus vaccines by enriching the population of surface-bound α2,6-sialic acid receptors on a cell surface, such as on a Chinese Hamster Ovary (CHO) cell surface. The host cell therefore presents numerous binding sites to which an influenza virus can bind via its hemagglutinin spike protein and infect the host cell. In contrast to wild-type CHO cells, the surface of the mutated CHO cells of the present invention contains an enriched population of α2,6-sialic acid receptors which makes the inventive CHO cells highly susceptible to viral infection, and therefore safe, effective, and highly efficient cells for rapidly producing influenza vaccines. | 01-28-2010 |
20100080825 | FILOVIRUS VECTORS AND NONINFECTIOUS FILOVIRUS-BASED PARTICLES - Cloned filovirus genomic cDNA and methods of using the cDNA are provided. Further provided are noninfectious lipid encapsulated filovirus-based particles. | 04-01-2010 |
20100267116 | Filovirus vectors and noninfectious filovirus-based particles - Cloned filovirus genomic cDNA and methods of using the cDNA are provided. Further provided are noninfectious lipid encapsulated filovirus-based particles. | 10-21-2010 |
20110150925 | CELL-BASED SYSTEMS FOR PRODUCING INFLUENZA VACCINES - The present invention relates to a cell-based method for producing influenza virus vaccines by enriching the population of surface-bound α2,6-sialic acid receptors on a cell surface, such as on a Chinese Hamster Ovary (CHO) cell surface. The host cell therefore presents numerous binding sites to which an influenza virus can bind via its hemagglutinin spike protein and infect the host cell. In contrast to wild-type CHO cells, the surface of the mutated CHO cells of the present invention contains an enriched population of α2,6-sialic acid receptors which makes the inventive CHO cells highly susceptible to viral infection, and therefore safe, effective, and highly efficient cells for rapidly producing influenza vaccines. | 06-23-2011 |
20110300604 | RECOMBINANT INFLUENZA VECTORS WITH TANDEM TRANSCRIPTION UNITS - The invention provides a composition useful to prepare influenza viruses, e.g., in the absence of helper virus, using vectors which include tandem transcription cassettes containing PolI and/or PolII promoters. | 12-08-2011 |
20120156758 | Recombinant Influenza Viruses for Vaccines and Gene Therapy - The invention provides compositions and methods useful to prepare segmented, negative strand RNA viruses, e.g., orthomyxoviruses such as influenza A viruses, entirely from cloned cDNAs and in the absence of helper virus. | 06-21-2012 |
20130230552 | INFLUENZA VIRUSES WITH MUTANT PB2 GENE SEGMENT AS LIVE ATTENUATED VACCINES - The invention provides a recombinant biologically contained influenza virus that is a PB2 knockout virus, e.g., one that is useful to generate a multivalent vaccine, and methods of making and using that virus. | 09-05-2013 |
20130267028 | Recombinant Influenza Viruses for Vaccines and Gene Therapy - The invention provides a composition useful to prepare influenza A viruses, e.g., in the absence of helper virus. | 10-10-2013 |
20140206062 | Recombinant Influenza Viruses for Vaccines and Gene Therapy - The invention provides compositions and methods useful to prepare segmented, negative strand RNA viruses, e.g., orthomyxoviruses such as influenza A viruses, entirely from cloned cDNAs and in the absence of helper virus. | 07-24-2014 |
20150017205 | HIGH TITER RECOMBINANT INFLUENZA VIRUSES WITH ENHANCED REPLICATION IN MDCK OR VERO CELLS OR EGGS - The invention provides a composition useful to prepare high titer influenza viruses, e.g., in the absence of helper virus, which includes internal genes from an influenza virus vaccine strain or isolate, e.g., one that is safe in humans, for instance, one that does not result in significant disease, that confer enhanced growth in cells in culture, such as MDCK cells, or in eggs. | 01-15-2015 |
20150307851 | INFLUENZA VIRUSES WITH MUTANT PB2 GENE SEGMENT AS LIVE ATTENUATED VACCINES - The invention provides a recombinant biologically contained influenza virus that is a PB2 knockout virus, e.g., one that is useful to generate a multivalent vaccine, and methods of making and using that virus. | 10-29-2015 |
Patent application number | Description | Published |
20090134239 | Volatile material dispensing system - A modular volatile material dispensing system includes a supporting plate having a front side and a rear side and an opening extending therethrough. A cover plate is releasably attached to the front side of the supporting plate to form a compartment therebetween. A volatile material dispenser is adapted to be held within the compartment and a modular adapter is releasably attached to the rear side of the supporting plate. | 05-28-2009 |
20100044453 | Diffusion device with odor sensor - An apparatus for treating an airspace with a volatile substance includes means for detecting the presence of a specific component in a volatile substance and means for controlling a volatile substance dispenser to dispense the volatile substance only if the volatile substance contains the specific component. | 02-25-2010 |
20100178042 | Fragrance dispenser - A fragrance dispenser includes a housing and a plurality of heating pans disposed in the housing. Each of the plurality of heating pans includes a corresponding heating element centrally disposed therein. A controller is disposed in the housing to control the amount and temporal distribution of power distributed to each heating element independently. Prongs extend from the housing to provide power to the controller. A volatile material holder is held within the housing and includes a plurality of reservoirs adapted to align with the corresponding plurality of heating pans, wherein each of the plurality of reservoirs includes a volatile material. | 07-15-2010 |
20120199665 | Volatile Material Dispensing System - A modular volatile material dispensing system includes a supporting plate having a front side and a rear side. The rear side of the supporting plate is configured to removably attach to an electrical plate and a non-electrical plate. The modular volatile material dispensing system includes a cover plate attached to the front side of the supporting plate to form a compartment therebetween, which is adapted to hold a volatile material therein. | 08-09-2012 |
Patent application number | Description | Published |
20110024466 | Automated Cleansing Sprayer - An automated sprayer for spraying the walls of a shower enclosure with a liquid cleanser dispenses the cleanser using a pumping system and rotatable spray head. The sprayer has a showerhead mountable housing with an adjustable hanger. There is a portion of the housing for supporting a bottle of cleanser in an inverted fashion. The bottle is vented through a piercing post. A single motor both drives the pump and rotates the spray head. | 02-03-2011 |
20110247651 | Fabric Sweeper - The present invention is a device for use in cleaning a fabric surface of dust, dirt, pet hair and other debris present on the surface. The device includes a housing coupled to a base. The base is coupled to at least one movable cleaning member configured to engage a surface for picking up debris from the surface. The debris is deposited into a debris collection chamber by way of interaction with another portion of the device. The debris collection chamber is selectively emptiable by an operator thereof so that the device may be subsequently reused. | 10-13-2011 |
20120138564 | Bottle With Top Loading Resistance - Bottles with improved top loading resistance are disclosed herein. The bottles may have generally “square” body profiles and may include structural features such as variable wall thickness, specific shoulder angles, and other structural reinforcement components. The bottle may have one or both of the following characteristics: a weight and barrel thickness specific top loading strength of no less than 2.30 lbf/g×mm and a weight and volume specific top loading strength of no less than 1.00 lbf×L/g. | 06-07-2012 |
20120175338 | Bottle with Top Loading Resistance with Front and Back Ribs - Bottles with improved top loading resistance are disclosed herein. The bottles may have generally “square” body profiles and may include structural features such as variable wall thickness, specific shoulder angles, and other structural reinforcement components. The bottles may include laterally extending ribs on the barrel to improve their lateral stacking strength, and may do so without adversely affecting their top loading strength. The bottles may have one or both of the following characteristics: a weight and barrel thickness specific top loading strength of no less than 2.30 lbf/g×mm and a weight and volume specific top loading strength of no less than 1.00 lbf×L/g. | 07-12-2012 |