Auricchio
Alberto Auricchio, Naples IT
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20090192115 | USE OF COMPOUNDS THAT INTERFERE WITH THE HEDGEHOG SIGNALING PATHWAY FOR THE MANUFACTURE OF A MEDICAMENT FOR PREVENTING, INHIBITING, AND/OR REVERSING OCULAR DISEASES RELATED WITH OCULAR NEOVASCULARIZATION - The use of compounds that interfere with the hedgehog signaling pathway for the manufacture of a medicament for preventing, inhibiting, and/or reversing ocular diseases related with ocular neovascularization. Particularly, the above-mentioned diseases are (wet) age-related macular degeneration, (proliferative) diabetic retinopathy, neovascular glaucoma, retinal vein occlusion, or retinopathy of prematurity (ROP). | 07-30-2009 |
Alberto Auricchio, Napoli IT
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20090214478 | Method of treating ocular diseases by gene therapy - A method for the treatment of diseases associated with mutations in ABCA4 gene by administering, to a subject in need thereof, an adeno-associated viral vector encoding an ABCR protein; genetic constructs and adeno-associated viral vectors for use in this method. | 08-27-2009 |
20110117058 | METHOD OF TREATING GENETIC DISORDERS - A method for the treatment of diseases associated with mutations in MYO7A or CEP290 genes, especially the Usher Syndrome type IB and Leber congenital amaurosis, by administering to a subject in need thereof an adeno-associated viral vector encoding a MYO7A or a CEP290 protein; genetic constructs and adeno-associated viral vectors for use in this method. | 05-19-2011 |
20160076054 | EFFECTIVE DELIVERY OF LARGE GENES BY DUAL AAV VECTORS - The present invention relates to constructs, vectors, relative host cells and pharmaceutical compositions which allow an effective gene therapy, in particular of genes larger than 5 Kb. | 03-17-2016 |
Angelo Auricchio, Magdeburg DE
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20080300643 | Heart failure therapy adjustment based on ventricular pressures - Pacing left and right ventricles of the heart for delivery of heart failure therapy involves measuring right ventricular (RV) pressure and a left ventricular (LV) pressure, and computing a parameter developed from one or both of the RV and LV pressure measurements. The parameter is indicative of a degree of left and right ventricular synchronization. At least one parameter of a heart failure pacing therapy is adjusted based on the parameter to improve synchronization of the right and left ventricles. | 12-04-2008 |
Angelo Auricchio, Ruvigliana CH
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20140243848 | SYSTEM FOR LEADLESS PACING OF THE HEART - Devices for use in providing stimulation to cardiac tissue are provided. One device is configured for implantation in or near the heart and includes a flexible, elongate body. The body is configured to be positioned across two different sections of the vasculature such that (a) the first end can be positioned in a first section of the vasculature through which the device can stimulate a first chamber of the heart and (b) the second end can be positioned in a second section of the vasculature through which the device can stimulate a second chamber of the heart. The device further includes a receiver circuit configured to receive signals wirelessly from a transmitter device and to convert the signals into electrical power. The device also includes at least a first set of one or more electrodes configured to stimulate the heart using the electrical power. | 08-28-2014 |
Ferdinando Auricchio, Napoli IT
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20100189776 | ANTI-ANDROGEN PEPTIDES AND USES THEREOF IN CANCER THERAPY - The present invention relates to isolated or purified or partially purified peptide derived molecules having the following general formula (S1): X-[(Pro) | 07-29-2010 |
20150202249 | ANTI-ANDROGEN PEPTIDES AND USES THEREOF IN CANCER THERAPY - The present invention relates to isolated or purified or partially purified peptide derived molecules having the following general formula (S1): X-[(Pro)n-His-Pro-His-Ala-Arg-Ile-Lys] | 07-23-2015 |
Fernando Auricchio, Naples IT
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20160068568 | MODULATORS OF THE SRC-KINASE ACTIVITY FOR PREVENTING OR TREATING METASTATIC CANCER - The invention provides a molecule that modulates an activity of a Src family kinase for use in preventing or treating a metastatic cancer a subject. Preferably, the molecule comprises or consists of the structure: B | 03-10-2016 |
Giovanni Auricchio, Ciampino IT
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20130202648 | Immunoregulator Compounds - The invention relates to sphingosine derivative compounds, like D-erythro-sphingosine | 08-08-2013 |