Patent application number | Description | Published |
20090017508 | Streptomyces Avermitilis Gene Directing The Ratio of B2:B1 Avermectins - The present invention relates to polynucleotide molecules comprising nucleotide sequences encoding an aveC gene product, which polynucleotide molecules can be used to alter the ratio or amount of class 2:1 avermectins produced in fermentation cultures of | 01-15-2009 |
20090118130 | Structure-activity relationships - The present disclosure relates to compositions and methods for screening a plurality of polypeptide variants. | 05-07-2009 |
20090191605 | Ketoreductase Polypeptides for the Reduction of Acetophenones - The present disclosure provides engineered ketoreductase enzymes having improved properties as compared to a naturally occurring wild-type ketoreductase enzyme. Also provided are polynucleotides encoding the engineered ketoreductase enzymes, host cells capable of expressing the engineered ketoreductase enzymes, and methods of using the engineered ketoreductase enzymes to synthesize a variety of chiral compounds. | 07-30-2009 |
20100028972 | KETOREDUCTASE POLYPEPTIDES AND RELATED POLYNUCLEOTIDES - The present invention is directed to variant polypeptides having enhanced ketoreductase activity and/or thermostability for use in the stereospecific reduction of ketones. In addition, the present invention is directed to polynucleotides that encode the ketoreductase polypeptides, including codon optimized versions of the polynucleotides which provide for enhanced expression in host cells. In another aspect, the present invention is directed to nucleotide constructs, vectors and host cells that are transformed with polynucleotides of the present invention. | 02-04-2010 |
20100143968 | PENICILLIN-G ACYLASES - The present disclosure relates to engineered penicillin G acylase (PGA) enzymes having improved properties, polynucleotides encoding such enzymes, compositions including the enzymes, and methods of using the enzymes. | 06-10-2010 |
20100304459 | GLUCOSE DEHYDROGENASE POLYPEPTIDES AND RELATED POLYNUCLEOTIDES - The present invention is directed to glucose dehydrogenase (GDH) polypeptides that have enhanced GDH activity and/or thermostability relative to the backbone wild-type glucose dehydrogenase polypeptide. In addition, the present invention is directed to a polynucleotide that encodes for the GDH polypeptides of the present invention, to nucleic acid sequences comprising the polynucleotides, to expression vectors comprising the polynucleotides operatively linked to a promoter, to host cells transformed to express the GDH polypeptides, and to a method for producing the GDH polypeptides of the present invention. | 12-02-2010 |
20120142063 | NITRILASE BIOCATALYSTS - The present disclosure relates to polypeptides having nitrilase activity, polynucleotides encoding the polypeptides, and methods of using the polypeptides. | 06-07-2012 |
20120270282 | PENICILLIN-G ACYLASES - The present disclosure relates to engineered penicillin G acylase (PGA) enzymes having improved properties, polynucleotides encoding such enzymes, compositions including the enzymes, and methods of using the enzymes. | 10-25-2012 |
20130078692 | KETOREDUCTASE POLYPEPTIDES FOR THE REDUCTION OF ACETOPHENONES - The present disclosure provides engineered ketoreductase enzymes having improved properties as compared to a naturally occurring wild-type ketoreductase enzyme. Also provided are polynucleotides encoding the engineered ketoreductase enzymes, host cells capable of expressing the engineered ketoreductase enzymes, and methods of using the engineered ketoreductase enzymes to synthesize a variety of chiral compounds. | 03-28-2013 |
20130157900 | STRUCTURE-ACTIVITY RELATIONSHIPS - The present disclosure relates to compositions and methods for screening a plurality of polypeptide variants. | 06-20-2013 |
20130165341 | STRUCTURE-ACTIVITY RELATIONSHIPS - The present disclosure relates to compositions and methods for screening a plurality of polypeptide variants. | 06-27-2013 |
20130344552 | KETOREDUCTASE POLYPEPTIDES FOR THE REDUCTION OF ACETOPHENONES - The present disclosure provides engineered ketoreductase enzymes having improved properties as compared to a naturally occurring wild-type ketoreductase enzyme. Also provided are polynucleotides encoding the engineered ketoreductase enzymes, host cells capable of expressing the engineered ketoreductase enzymes, and methods of using the engineered ketoreductase enzymes to synthesize a variety of chiral compounds. | 12-26-2013 |
20150017695 | KETOREDUCTASE POLYPEPTIDES FOR THE REDUCTION OF ACETOPHENONES - The present disclosure provides engineered ketoreductase enzymes having improved properties as compared to a naturally occurring wild-type ketoreductase enzyme. Also provided are polynucleotides encoding the engineered ketoreductase enzymes, host cells capable of expressing the engineered ketoreductase enzymes, and methods of using the engineered ketoreductase enzymes to synthesize a variety of chiral compounds. | 01-15-2015 |
20150191767 | STRUCTURE-ACTIVITY RELATIONSHIPS - The present disclosure relates to compositions and methods for screening a plurality of polypeptide variants. | 07-09-2015 |
Patent application number | Description | Published |
20120118721 | DEVICE FOR COMPENSATING DEVIATIONS FROM A COAXIAL ARRANGEMENT OF COMPONENTS OF A REGULATING ORGAN TO CONTROL THE GAS PRESSURE IN A COKE OVEN CHAMBER - A device for compensating for deviations from a coaxial arrangement of components of a regulating organ for controlling and regulating the gas pressure of a coke oven chamber includes a water inflow into an immersion cup having a water immersion that seals the free gas space of a coke oven chamber versus the exterior atmosphere. The level of the water immersion represents a regulation to control the gas pressure in the coke oven chamber. The regulating arrangement also includes an immersion pipe which at its end is submerged in the water and at this end forms a specially shaped crown pipe. The regulating arrangement also has a regulating organ to control and regulate the water inflow. The device by way of a flexible suspension of the immersion cup and by way of guiding elements at the outer side of the crown pipe or at the inner side of the immersion cup ensures that no deviations occur in the alignment of the coaxial regulating arrangement, and the lock plug of this regulating organ always moves correctly into the envisaged sealing seat of the immersion cup. | 05-17-2012 |
20120261244 | METHOD OF REDUCING NITROGEN OXIDES FROM COKE-OVEN FLUE GAS - The invention relates to a method for reducing nitrogen oxides from the exhaust gas of a coke oven, which has a plurality of coking chambers and heating walls, arranged between the coking chambers, with heating flues ( | 10-18-2012 |
20130143170 | CRUDE GAS TORCH COMPRISING AN ADJUSTABLE OPENING CROSS-SECTION FOR FLARING COMBUSTIBLE GASES AND METHOD FOR BURNING CRUDE GASES - A device for flaring combustible gases, having an adjustable opening cross-section, and three tubes arranged about a common longitudinal axis. The tubes are arranged at least in some sections in a common cross-sectional plane an inner tube is designed as a gas introduction tube and has an opening that ends at the top in the vertical direction a diaphragm that can be adjusted in the cross section, through which the gas stream can be closed or regulated and which is fitted with an automatable mechanism for adjusting the opening cross-section. The device typically contains also at least one air guiding plate, feed devices for an inert gas and an ignition mechanism, thereby ensuring a high reliability for flaring the gas and a low emission of nitrogen oxides and soot. A method for operating the device which is suitable for flaring crude gases which are to be combusted is also disclosed. | 06-06-2013 |
20130180514 | DEVICE AND METHOD FOR SETTING UP A CONTROL ELEMENT FOR THE GAS PRESSURE OF A COKE OVEN CHAMBER WITHOUT EXPANSION-INDUCED DEVIATIONS OF THE CONTROL ASSEMBLY - A device for setting up a control element for controlling the gas pressure of a coke oven chamber without expansion-induced deviations of the control assembly, which deviations in comparable devices from the prior art result from high temperatures and temperature differences in coke oven chambers during operation. The device and the method prevent water used for shutting off, cooling and removing water-soluble impurities from riser pipes from flowing out of the control element in an uncontrolled manner. Also disclosed is a method for controlling the gas pressure of a coke oven chamber using the device, wherein the pressure in the coke oven chamber relative to the collecting main conducting raw gas is controlled by using the control element without expansion-induced deviations of the regulating assembly. | 07-18-2013 |
20140054157 | DEVICE AND METHOD FOR REGULATING THE CHAMBER PRESSURE OF COKING CHAMBERS OF A COKE-OVEN BATTERY USING ADJUSTABLE DIAPHRAGMS AT THE ASCENDING PIPE ELBOW OPENINGS INTO THE RAW GAS RECEIVERS - A device for regulating the chamber pressure of coking chambers of a coke-oven battery using adjustable iris diaphragms or iris nozzles at the ascending pipe elbow openings in the raw gas receiver. The gas stream flowing from the gas chamber of a coking chamber into the raw gas receiver can thus be regulated so that the pressure in the gas chamber of the coking chamber can be controlled. A method is also disclosed for regulating the gas stream which flows out the gas chamber of a coking chamber, wherein the pressure in the coking chamber is regulated by the control, and wherein also the liquid stream is regulated which serves to wash out the coking gases from the raw gas stream of the coking chamber. | 02-27-2014 |