Khanna, US
Abha Khanna, Sugar Land, TX US
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20110189670 | Circulating Tumor and Tumor Stem Cell Detection Using Genomic Specific Probes - The present invention comprises a method of detecting circular tumor cells and methods of detecting, evaluating, or staging cancer in a patient, as well as a method of monitoring treatment of cancer in a patient using the claimed method. The method comprises contacting a sample with a CD45 binding agent; selecting the cells based on positive or negative CD45 staining; contacting the selected cells with a labeled nucleic acid probe, and detecting hybridized cells by fluorescence in situ hybridization; and analyzing a signal produced by the labels on the hybridized cells to detect the CTCs. In other embodiments, the method provides for directed to a method of determining the level of CTCs in a sample having blood cells from a patient by contacting a sample having blood cells from a patient, wherein the sample has not been pre-sorted into CD45-positive and CD45-negative cells. | 08-04-2011 |
Abha Khanna, Houston, TX US
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20090162839 | DIAGNOSIS AND PROGNOSIS OF CANCER BASED ON TELOMERE LENGTH AS MEASURED ON CYTOLOGICAL SPECIMENS - The present invention concerns a quantitative in situ assessment of mean telomere length, particularly in relation to nuclear area, for the diagnosis and/or prognosis of cancer. In particular aspects, the methods and compositions regard diagnosis and/or prognosis of bladder cancer, urothelial cancer, lung cancer, and lymphoma. | 06-25-2009 |
Achla Khanna, Aurora, IL US
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20150056895 | ULTRA HIGH VOID VOLUME POLISHING PAD WITH CLOSED PORE STRUCTURE - The invention provides a polishing pad for chemical-mechanical polishing comprising a porous polymeric material, wherein the polishing pad comprises closed pores and wherein the polishing pad has a void volume fraction of 70% or more. Also disclosed is a method for preparing the aforesaid polishing pad and a method of polishing a substrate by use of theaforesaid polishing pad. | 02-26-2015 |
A. Jay Khanna, Potomac, MD US
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20120271363 | UNIVERSALLY DEPLOYABLE AND EXPANDABLE BONE SCREW ANCHOR - A self-expanding bone screw anchor assembly adapted to allow the screw body to engage the bone and the anchor to attach thereto. The anchor assembly is adapted to be universally deployed with a variety of installation tools. | 10-25-2012 |
Akhil Jay Khanna, Potomac, MD US
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20150045799 | Bone Harvesting - Methods and devices for harvesting cancellous bone are disclosed. The bone-harvesting device may include a cannula and a bone receptacle in communication with the cannula, wherein the cannula including a cutting surface positioned at or adjacent the distal end, the cutting surface being oriented at an angle, the angle being greater than 90 degrees relative to the longitudinal axis of the cannula, and the harvested bone is adapted to move from a position adjacent to the cutting surface through the cannula into the bone receptacle. The cutting surface of the cannula may be positioned at or adjacent the distal end, and positioned at least in part radially outward of the outer face of the cannula. The cannula may include a cutting surface positioned at or adjacent the distal end and an occluding geometry that partially occludes the distal end of the cannula adjacent the cutting surface. In addition, a suction port may be provided in communication with the bone receptacle. | 02-12-2015 |
Akhil Jay Khanna, Baltimore, MD US
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20130317507 | MINIMALLY-INVASIVE DEVICE, KIT, AND METHOD FOR HARVESTING BONE GRAFT - A minimally-invasive bone graft harvesting device, kit, and method are provided. The device includes a hollow cutting element and an extraction element. The hollow cutting element may define a longitudinal axis and includes a distal end, a proximal end adapted to be coupled to a powered or manual-operated rotary tool, and an inner lumen extending longitudinally between the distal and proximal ends. The hollow cutting element may also include one or more blades protruding from an outer surface of the cutting element. Each blade may be arranged adjacent to an opening extending between the outer surface and the inner lumen to allow cancellous bone material cut by each blade during use to pass through the opening into the inner lumen. The extraction element may be removably received within the inner lumen of the hollow cutting element to allow withdrawal of the bone material in the inner lumen. | 11-28-2013 |
20140188115 | MINIMALLY-INVASIVE DEVICE, KIT, AND METHOD FOR HARVESTING BONE GRAFT - A minimally-invasive bone graft harvesting device, kit, and method are provided. The device includes a hollow cutting element and an extraction element. The hollow cutting element may define a longitudinal axis and includes a distal end, a proximal end adapted to be coupled to a powered or manual-operated rotary tool, and an inner lumen extending longitudinally between the distal and proximal ends. The hollow cutting element may also include one or more blades protruding from an outer surface of the cutting element. Each blade may be arranged adjacent to an opening extending between the outer surface and the inner lumen to allow cancellous bone material cut by each blade during use to pass through the opening into the inner lumen. The extraction element may be removably received within the inner lumen of the hollow cutting element to allow withdrawal of the bone material in the inner lumen. | 07-03-2014 |
Aloka Khanna, Troy, NY US
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20150130346 | NARROW SPECTRAL LINE-WIDTH EMISSION PHOSPHORS WITH BROAD BAND EXCITATION EDGE UP TO AND INCLUDING THE BLUE WAVELENGTH REGION - Aspects of the present invention provide a family of phosphor compositions that may be used in the field of lighting applications. These phosphor compositions have crystal structures and chemical bond arrangements that enable broad band absorption and excitation using radiation up to and including the blue wavelength region. A preferred embodiment of the phosphor compositions has a general formula of (A | 05-14-2015 |
Anil K. Khanna, Englewood, CO US
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20150256550 | LOCATION AWARE SECURITY SYSTEM - Methods, computing devices, and systems that dynamically determine whether a request is authorized or fraudulent are described herein. A computing device may receive a request from a communication device, and a geographical location of the communication device may be determined. User information may be requested, and based on the information and the geographical location of the communication device, a risk value can be calculated. A determination of whether to honor the request may be based on the subscriber risk value. | 09-10-2015 |
Ankit Khanna, Tucson, AZ US
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20140089362 | Modified Fixed-Point Algorithm For Implementing Infrared Sensor Radiation Equation - A system including an integrated circuit chip also includes a microcontroller in the chip and an algorithm for execution by the microcontroller. The algorithm includes addition, subtraction, and multiplication operators (e.g. | 03-27-2014 |
Anupama Khanna, Madison, WI US
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20150291942 | MODIFIED TRANSPOSASES FOR IMPROVED INSERTION SEQUENCE BIAS AND INCREASED DNA INPUT TOLERANCE - Presented herein are transposase enzymes and reaction conditions for improved fragmentation and tagging of nucleic acid samples, in particular altered transposases and reaction conditions which exhibit improved insertion sequence bias, as well as methods and kits using the same. | 10-15-2015 |
Ashish Khanna, Maricopa, AZ US
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20100188105 | CAPACITANCE-TO-VOLTAGE INTERFACE CIRCUIT, AND RELATED OPERATING METHODS - A capacitance-to-voltage interface circuit is utilized to obtain a voltage corresponding to a detected capacitance differential, which may be associated with the operation of a capacitive sensing cell. The interface circuit includes a capacitive sensing cell, an operational amplifier adapted for selective coupling to the capacitive sensing cell, a feedback capacitor for the operational amplifier, a load capacitor for the operational amplifier, and a switching architecture associated with the capacitive sensing cell, the operational amplifier, the feedback capacitor, and the load capacitor. During use, the switching architecture reconfigures the capacitance-to-voltage interface circuit for operation in a plurality of different phases. The different operational phases enable the single operational amplifier to be used for both capacitance-to-voltage conversion and voltage amplification. | 07-29-2010 |
20100188107 | CAPACITANCE-TO-VOLTAGE INTERFACE CIRCUIT WITH SHARED CAPACITOR BANK FOR OFFSETTING AND ANALOG-TO-DIGITAL CONVERSION - A capacitance-to-voltage interface circuit includes a capacitive sensing circuit, an amplification circuit adapted for selective coupling to the capacitive sensing circuit, a capacitor bank comprising a plurality of binary-weighted capacitors, and a switching architecture associated with the capacitive sensing circuit, the amplification circuit, and the capacitor bank. The switching architecture reconfigures the capacitance-to-voltage interface circuit for operation in a plurality of different phases, including an amplification phase and an analog-to-digital conversion phase. During the amplification phase, the capacitor bank is utilized for offsetting capacitance of the amplification circuit. During the analog-to-digital conversion phase, the capacitor bank is utilized in a successive approximation register. | 07-29-2010 |
20100188278 | CHARGE REDISTRIBUTION SUCCESSIVE APPROXIMATION ANALOG-TO-DIGITAL CONVERTER AND RELATED OPERATING METHOD - The analog-to-digital converter provided herein includes a capacitor bank comprising a plurality of binary-weighted capacitors, an operational amplifier having an inverting input node, a noninverting input node coupled to analog ground, and an output node, a reset switch, and an input switch. The reset switch is located between the capacitor bank and the operational amplifier, and it selectively couples the capacitor bank to the inverting input node. The input switch has its common terminal coupled to the capacitor bank, and the input switch selectively couples the capacitor bank to either an analog input voltage, a floating terminal, or analog ground. The capacitor bank includes N binary-weighted capacitors and one balacing capacitor that has a unit capacitance. During operation, the analog-to-digital converter generates an N-bit digital output and one polarity bit from the analog input voltage. | 07-29-2010 |
20120105079 | CAPACITANCE-TO-VOLTAGE INTERFACE CIRCUITS - A capacitance-to-voltage interface circuit is utilized to obtain a voltage corresponding to a detected capacitance differential, which may be associated with the operation of a capacitive sensing cell. The interface circuit includes a capacitive sensing cell, an operational amplifier adapted for selective coupling to the capacitive sensing cell, a feedback capacitor for the operational amplifier, a load capacitor for the operational amplifier, and a switching architecture associated with the capacitive sensing cell, the operational amplifier, the feedback capacitor, and the load capacitor. During use, the switching architecture reconfigures the capacitance-to-voltage interface circuit for operation in a plurality of different phases. The different operational phases enable the single operational amplifier to be used for both capacitance-to-voltage conversion and voltage amplification. | 05-03-2012 |
20140253148 | CAPACITANCE-TO-VOLTAGE INTERFACE CIRCUITS - A capacitance-to-voltage interface circuit is utilized to obtain a voltage corresponding to a detected capacitance differential, which may be associated with the operation of a capacitive sensing cell. The interface circuit includes a capacitive sensing cell, an operational amplifier adapted for selective coupling to the capacitive sensing cell, a feedback capacitor for the operational amplifier, a load capacitor for the operational amplifier, and a switching architecture associated with the capacitive sensing cell, the operational amplifier, the feedback capacitor, and the load capacitor. During use, the switching architecture reconfigures the capacitance-to-voltage interface circuit for operation in a plurality of different phases. The different operational phases enable the single operational amplifier to be used for both capacitance-to-voltage conversion and voltage amplification. | 09-11-2014 |
Ashok K. Khanna, Lake Zurich, IL US
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20110236258 | MEDICAL FLUID ACCESS DEVICE WITH ANTISEPTIC INDICATOR - A medical device, such as a vascular access device, is disclosed for providing access to a medical fluid flow path for the introduction or withdrawal of medical fluids to and from the flow path. The access device includes an indicator for providing a visual indication when the access device has been exposed to an antiseptic agent. | 09-29-2011 |
20130224866 | MEDICAL FLUID ACCESS DEVICE WITH ANTISEPTIC INDICATOR - A medical device, such as a vascular access device, is disclosed for providing access to a medical fluid flow path for the introduction or withdrawal of medical fluids to and from the flow path. The access device includes an indicator for providing a visual indication when the access device has been exposed to an antiseptic agent. The indicator includes a substrate and a microporous layer disposed on the substrate. The microporous layer is made from a polymer material having an index of refraction from about 1.25 to about 1.6 and is configured to change from a substantially opaque state to a substantially transparent state upon exposure to an antiseptic solution. The microporous layer resumes the substantially opaque state after a period of time. | 08-29-2013 |
Ashwani K. Khanna, Brookfield, WI US
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20090035304 | Use of Tgf-beta Antagonists to Limit Nephrotoxicity of Immunosuppressive Agents - The disclosure relates to methods of ameliorating nephrotoxic side effects of immunosuppressive agents whose immunosuppressive activity is mediated via upregulation of TGF-β such as, for example, cyclosporine (CsA). The disclosure provides treatment modalities for use in patients that require immunosuppression, e.g., patients at risk of transplant rejection or having an autoimmune disease. In the methods of the invention, a TGF-β antagonist, e.g., an anti-TGF-β antibody, is administered to a patient treated with an immunosuppressive agent. Such a TGF-β antagonist is administered in a therapeutically effective amount sufficient to alleviate the nephrotoxic effects of the immunosuppressive agent without substantially interfering with immunosuppressive activity of the agent. | 02-05-2009 |
Bakul Khanna, Lexington, MA US
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20090158417 | Anti-replay protection with quality of services (QoS) queues - An embodiment of the present invention includes a technique to provide anti-replay protection with QoS queues. A single global anti-replay window is maintained to have global lowest and highest sequence numbers for an Internet protocol security (IPSec) security association (SA). The single global anti-replay window is associated with individual differentiated services code point (DSCP) or DSCP group, the individual DSCP or DSCP group corresponding to individual per-DSCP anti-replay windows. A received packet having a sequence number is pre-processed before packet processing using the single global anti-replay window. The received packet is post-processed after packet processing using the individual per-DSCP anti-replay windows. | 06-18-2009 |
20100329252 | Method and Apparatus for Enabling Multicast Route Leaking Between VRFs in Different VPNs - Multicast route leaking between VRFs in different VPNs enables receivers in different VPNs to subscribe to the same IP multicast so that an efficient IP multicast distribution tree can be built to include subscribers in multiple VPNs. VRFs are administratively configured to implement multicast route leaking and each such configured VRF brings up an internal connectionless IP interface. The VRFs then enable the multicast routing protocol (e.g. PIM) on the internal IP interface to establish PIM neighborships with each other. When a VRF receives an IGMP join from a receiver, it uses PIM to join the receiver to the multicast over the internal IP interface. This enables receivers outside of a VPN but associated with VRFs that are co-located on the same PE to join multicasts established within the VPN so that separate multicast distribution trees are not required for each VPN. | 12-30-2010 |
Bakul Grover Khanna, Lexington, MA US
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20130148658 | SYSTEMS AND METHODS FOR SCALABLE MULTICAST COMMUNICATION USING SELF-ROOTED FORWARDING TREES - Systems and methods are disclosed herein for multicasting a data packet through a wireless network. The method includes a packet metadata which maintains a set of next-hop nodes on the routing path as well as the assigned destination nodes of the packet. In addition, each node maintains only a single self-rooted forwarding tree for determining the routing path. By using the metadata in conjunction with a single forwarding tree at each node, the method introduces a highly scalable alternative to multicast protocols based on link state routing source-based trees while substantially reducing the processor load. Furthermore, the method does not require a consistent view of the network topology, making it useful in mobile scenarios. Also included is a mechanism to minimize the packet metadata size for minimal impact to performance while supporting arbitrarily large multicast group sizes. | 06-13-2013 |
20140341227 | DISRUPTED ADAPTIVE ROUTING - According to one aspect, embodiments of the invention provide a node comprising a processor, a memory including a predefined mapping, the predefined mapping correlating network characteristics to related critical thresholds at which a delivery ratio of the node is close to a maximum level and at which a total number of transmissions by the node is close to a minimum number necessary to achieve the delivery ratio, and a component configured to communicate with one-hop neighbors of the node and configured to determine at least one characteristic of a dynamic network based on information received from the one-hop neighbors of the node, wherein, in reference to the predefined mapping, the processor is configured to identify a critical threshold associated with the at least one characteristic of the network and is configured to transmit a first packet to at least one one-hop neighbor based on the critical threshold. | 11-20-2014 |
Chand Khanna, Chevy Case, MD US
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20100041617 | Modulating mxa expression - The invention provides compositions and methods for inhibiting cell motility, metastatic cancer and viral infections in a mammal that involve increasing the activity or expression of MxA. | 02-18-2010 |
Dinesh Khanna, Naperville, IL US
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20110014858 | GROOVED CMP POLISHING PAD - The present invention provides polishing pads for use in CMP processes. In one embodiment, a pad comprises a surface defining a plurality of grooves with landing surfaces separating the grooves, the landing surfaces together defining a substantially coplanar polishing surface, each groove having a depth of at least about 10 mil and a width, W | 01-20-2011 |
Gaurav Khanna, Redmond, WA US
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20100287414 | EXCEPTION RAISED NOTIFICATION - An exception notification system is described herein that provides an early notification that a software exception has occurred before exception handling code has run. The exception notification system receives a registration request from program code to register a handler to receive an early notification when an exception occurs. When an exception occurs, the system raises an event that calls each registered handler. After the handler returns, the system performs normal exception handling, so that the early notification does not change existing exception-handling behavior. The exception notification system allows a program to inspect and log an exception before the program state has been modified by exception handling. The program code can capture detailed information about the cause of the exception to enable further offline analysis. Thus, the exception notification system allows developers to improve their programs by receiving more information about unexpected conditions in the program code. | 11-11-2010 |
Gautam Khanna, Louisville, CO US
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20130001169 | Metal removal system and method - A metal removal system and method are disclosed. An example method includes providing a sorptive media and providing a primary ligand having an affinity for the sorptive media, the primary ligand being an amphipathic, heterocyclic metal-coordinating compound. The method also includes providing a co-ligand having an affinity for the sorptive media. During a treatment process, a metal removal response is observed to be non-proportional between expected metal removal ability based on individual metal coordination abilities of the media alone and of all ligands, and actual net metal removal capacity resulting from a heterogeneous cooperation of the primary ligand and the sorptive media and activated by the co-ligand. | 01-03-2013 |
20130161261 | SYSTEM FOR DYNAMIC FLUIDIZED LOADNG OF A LIGAND UPON CARBON MEDIA AND METHODS ASSOCIATED THEREWITH - Method and systems are provided for the removal of metal contaminants from aqueous mediums using a chamber containing activated sorptive media and a primary ligand and optionally, a secondary ligand that has been loaded onto the activated sorptive media using hydraulic loading. In at least one embodiment, the methods and systems include a pre-treatment of the sorptive media, a specific volume of the activated sorptive media within the chamber, specific pH ranges of aqueous mediums, and hydraulic loading of the primary ligand and optionally, a secondary ligand, known as dynamic fluidized loading. In at least one embodiment, pore pressures of the seeding solution within the media are at least sufficient to overcome the gravitational forces acting on the media within the column. The methods and systems provide for a highly uniform and predictable loading of the primary ligand and optionally, the secondary ligand, onto the activated sorptive media throughout the sorptive media within the chamber. Thus, the methods and system provide for effective sorption and increased capacity for metal removal from aqueous mediums. | 06-27-2013 |
20150060365 | SYSTEM FOR DYNAMIC FLUIDIZED LOADING OF A LIGAND UPON CARBON MEDIA AND METHODS ASSOCIATED THEREWITH - Method and systems are provided for the removal of metal contaminants from aqueous mediums using a chamber containing activated sorptive media and a primary ligand and optionally, a secondary ligand that has been loaded onto the activated sorptive media using hydraulic loading. In at least one embodiment, the methods and systems include a pre-treatment of the sorptive media, a specific volume of the activated sorptive media within the chamber, specific pH ranges of aqueous mediums, and hydraulic loading of the primary ligand and optionally, a secondary ligand, known as dynamic fluidized loading. In at least one embodiment, pore pressures of the seeding solution within the media are at least sufficient to overcome the gravitational forces acting on the media within the column. The methods and systems provide for a highly uniform and predictable loading of the primary ligand and optionally, the secondary ligand, onto the activated sorptive media throughout the sorptive media within the chamber. Thus, the methods and system provide for effective sorption and increased capacity for metal removal from aqueous mediums. | 03-05-2015 |
Gunjan Khanna, West Lafayette, IN US
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20080222638 | Systems and Methods for Dynamically Managing Virtual Machines - Techniques for dynamic management of virtual machine environments are disclosed. For example, a technique for automatically managing a first set of virtual machines being hosted by a second set of physical machines comprises the following steps/operations. An alert is obtained that a service level agreement (SLA) pertaining to at least one application being hosted by at least one of the virtual machines in the first set of virtual machines is being violated. Upon obtaining the SLA violation alert, the technique obtains at least one performance measurement for at least a portion of the machines in at least one of the first set of virtual machines and the second set of physical machines, and a cost of migration for at least a portion of the virtual machines in the first set of virtual machines. Based on the obtained performance measurements and the obtained migration costs, an optimal migration policy is determined for moving the virtual machine hosting the at least one application to another physical machine. | 09-11-2008 |
Ish Khanna, Alpharetta, GA US
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20080214531 | Methods and compositions for the treatment of insulin resistance, diabetes, and diabetes-associated dyslipdemia - Methods for the treatment of insulin resistance, diabetes, and/or diabetes associated dyslipidemia by administering niacin and meloxicam are disclosed. | 09-04-2008 |
20080275049 | Methods and Compositions for Upregulation of GATA Activity - A novel method of identifying compounds capable of upregulating GATA activity is disclosed. The method includes providing a sample of cells that express GATA, providing a sample of a candidate compound, contacting the cell sample and the compound sample, and measuring a quantitative indicator of GATA activity within the cell sample after the contacting step. GATA inducers identified by the method and uses therefore to upregulate GATA activity in subjects and to prevent or treat atherosclerosis or diabetes in subjects are also described. | 11-06-2008 |
20100297673 | METHODS AND COMPOSITIONS FOR UPREGULATION OF PEROXIREDOXIN ACTIVITY - A novel method of identifying compounds capable of upregulating Peroxiredoxin activity is disclosed. The method includes providing a sample of cells that express Peroxiredoxin, providing a sample of a candidate compound, contacting the cell sample and the compound sample, and measuring a quantitative indicator of Peroxiredoxin activity within the cell sample after the contacting step. Peroxiredoxin inducers identified by the method and uses therefore to upregulate Peroxiredoxin activity in subjects and to reduce LDL and/or VLDL levels and to prevent or treat atherosclerosis and inflammatory disorders such as arthritis in subjects are also described. The invention also provides a method of treatment of inflammatory and cardiovascular diseases which comprises providing a patient in need of treatment with an effective amount of a composition that increases Peroxiredoxin protein or activity. | 11-25-2010 |
20120071528 | METHODS AND COMPOSITIONS FOR TREATMENT OF DIABETES AND DYSLIPIDEMIA - The invention is directed to novel compounds of Formula I: | 03-22-2012 |
20140121267 | METHODS AND COMPOSITIONS FOR TREATMENT OF DIABETES AND DYSLIPIDEMIA - Novel compounds of Formula A1 are provided: | 05-01-2014 |
20140142178 | METHODS AND COMPOSITIONS FOR TREATMENT OF DIABETES AND DYSLIPIDEMIA - Novel compounds of Formula I are provided: | 05-22-2014 |
Ish Kumar Khanna, Alpharetta, GA US
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20100144722 | NOVEL HETEROCYCLIC COMPOUNDS AS GATA MODULATORS - Novel heterocyclic compounds, sstereoisomers thereof and/or pharmaceutically acceptable salts of formula (I) and its stereoisomers are provided. Additionally, methods of forming novel heterocyclic compounds, stereoisomers thereof and/or pharmaceutically acceptable salts of formula (I) and its stereoisomers are provided. | 06-10-2010 |
20100144731 | Novel Biccyclic Compounds As GATA Modulators - Novel bicyclic compounds, stereoisomers, and/or pharmaceutically acceptable salts of the novel bicyclic compounds, and/or pharmaceutically acceptable salts of the stereoisomers of the novel bicyclic compounds are provided. Additionally, methods of forming novel bicyclic compounds, stereoisomers, and/or pharmaceutically acceptable salts of the novel bicyclic compounds, and/or pharmaceutically acceptable salts of the stereoisomers of the novel bicyclic compounds are provided. | 06-10-2010 |
20110086074 | COMBINATIONS OF NIACIN AND AN OXICAM - Pharmaceutical formulations comprising a combination of niacin and an oxicam NSAID, for oral administration, and methods of preparing the formulations. | 04-14-2011 |
20110123575 | MODIFIED RELEASE NIACIN FORMULATIONS - Modified release pharmaceutical formulations comprising niacin in a non-swellable core, and processes for preparation of the formulations. | 05-26-2011 |
20120064161 | MODIFIED RELEASE NIACIN PHARMACEUTICAL FORMULATIONS - Pharmaceutical formulations comprising niacin in a matrix comprising a hydrophobic polymer that modifies release of niacin. | 03-15-2012 |
20140134235 | NOVEL BENZYLAMINE DERIVATIVES AND THEIR UTILITY AS CHOLESTEROL ESTER-TRANSFER PROTEIN INHIBITORS - The present invention provides, among other things, new benzylamine compounds, compositions comprising benzylamine compounds, methods of making benzylamine compounds, and methods of using benzylamine compounds for treating or preventing a variety of conditions or diseases associated with lipoprotein metabolism. | 05-15-2014 |
20150216866 | SUBSTITUTED BENZYLAMINO QUINOLINES AS CHOLESTEROL ESTER-TRANSFER PROTEIN INHIBITORS - The present invention provides a method for treating or preventing a condition or disease in a human or an animal subject wherein the condition or disease is associated with lipoprotein metabolism, the method comprising administering to the subject a composition comprising benzylamine compounds. | 08-06-2015 |
Karan Khanna, Redmond, WA US
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20150124791 | DELIVERY OF SHARED WIFI CREDENTIALS - Various technologies described herein pertain to delivering shared WiFi credentials. According to various embodiments, at least one server computing device is configured to transmit shared WiFi credentials to a mobile device. The at least one server computing device receives a request, where the request includes data that identifies the mobile device. Moreover, the request indicates that the mobile device desirably receives credentials for a shared WiFi network. Responsive to receiving the request, the at least one server computing device determines that the mobile device is authorized to receive the credentials for the shared WiFi network based at least in part upon the data that identifies the mobile device. Moreover, the at least one server computing device transmits the credentials for the shared WiFi network to the mobile device responsive to determining that the mobile device is authorized to receive the credentials for the shared WiFi network. | 05-07-2015 |
Krishn Khanna, Colorado Springs, CO US
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20090112198 | LIQUID LIGHT GUIDE CATHETER HAVING BIOCOMPATIBLE LIQUID LIGHT GUIDE MEDIUM - A catheter system to ablate target matter within a mammalian body using light energy is described. The system may include an open-ended catheter tip through which a liquid light guide medium flows to the target matter, where at least a portion of the liquid light guide medium exiting the catheter tip creates a fluid optical channel to transmit the light energy from the catheter tip to the target matter. The system may also include a catheter lumen whose distal end includes the open-ended catheter tip, a light source to generate the light energy, and a liquid light guide medium source fluidly coupled to the catheter lumen. The liquid light guide medium source may include a reservoir of the liquid light guide medium that includes a magnesium chloride solution or a lactated Ringer's solution. | 04-30-2009 |
Kumar Gaurav Khanna, Woodinville, WA US
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20120304026 | SEPARATION OF ERROR INFORMATION FROM ERROR PROPAGATION INFORMATION - A system and method for handling exceptions in a multi-threaded computing environment. Information, such as that relating to an error state or pertaining to the propagation history of an exception, is stored in a separate object from the exception object itself. The separate propagation information object is accessible to the plurality of threads that are used to execute a user task. The separate object allows rich diagnostic information pertaining to the exception and its propagation through multiple threads to be presented to the developer of the software. | 11-29-2012 |
20140337824 | OUT-OF-BAND FRAMEWORK LIBRARIES WITHIN APPLICATIONS - An enhanced binder provides flexibility and certainty when selecting a version of a software library to load, and an enhanced loader prevents a library version vulnerable to a security flaw from being loaded. The binder can perform unification, implicit override, and/or redirection. Implicit override searches assembly-specific locations for an implicit_version, and override the previously chosen unification or other version with the implicit_version when the implicit_version is greater. The implicit_version gets updated with the individual assembly, whereas the unification_version gets updated with the framework. Redirection may override the implicit_version. Unlike redirection, an implicit_version does not recite an explicit range and is found outside application configuration files. The implicit_version is specified implicitly by the assembly without an XML declaration. Vulnerable libraries are not loaded, based on out-of-band metadata placed in response to a list of known out-of-band assemblies, an out-of-band-servicing attribute, or a custom servicing library. | 11-13-2014 |
Kumar Gaurav Khanna, Redmond, WA US
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20100218169 | CONTRACT FAILURE BEHAVIOR WITH ESCALATION POLICY - An error handling system is described herein that provides a facility for controlling the behavior of software when the software violates a contract condition. The system provides configurable runtime behavior that takes place when a contract fails. The error handling system provides an event that a hosting application or other software code can register to handle and that the system invokes upon detecting a contract failure. The application's response to the event determines how the system handles the failure. If the event is unhandled, the system triggers an escalation policy that allows an administrator or application to specify how the system handles contract failures. Thus, the error handling system provides increased control over the handling of contract failures within software code. | 08-26-2010 |
20100262814 | HANDLING EXCEPTIONS RELATED TO CORRUPT APPLICATION STATE - An exception handling system is described herein that provides one or more distinguished classes of software exceptions that are handled differently than other exceptions. The system treats a distinguished exception as a “hard to catch” exception that is not passed to the catch block of program code unless a developer performs extra steps to acknowledge the distinguished nature of the exception and confirm that the program code is prepared to properly handle the exception. Exceptions that fall into this class are typically those that represent conditions from which normal exception handling practices cannot successfully recover, namely exceptions that corrupt application state. Accordingly, the system prevents the developer from catching these classes of exceptions by default unless the developer explicitly requests to have these exceptions delivered to the program code. Thus, the exception handling system encourages correct programming practices by preventing developer error by default. | 10-14-2010 |
20110145662 | COORDINATION OF ERROR REPORTING AMONG MULTIPLE MANAGED RUNTIMES IN THE SAME PROCESS - Systems and methods are described for coordinating error reporting among a plurality of managed runtimes that are concurrently executing in the same process. In accordance with various embodiments, an error reporting manager that executes concurrently in the same process as the managed runtimes coordinates error reporting among the managed runtimes in a manner that does not require the managed runtimes to be aware of each other or to communicate directly with each other. | 06-16-2011 |
Kunaal Khanna, Chicago, IL US
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20080231744 | Machine having camera and mounting strategy therefor - A machine includes a frame having ground engaging elements for propelling a machine, and a body mounted to the frame. The body includes a plurality of body components, one of which is contoured for mounting a camera that includes a continuous face and a pocket each formed in an outer surface thereof. The method of assembling a machine includes molding a unitary body component for machine body, the body component having an outer surface with a continuous face and a pocket. The method further includes mounting a camera within the pocket and establishing an electrical link between the camera and an electrical system of the machine via a port disposed in the pocket which extends through the outer surface. | 09-25-2008 |
Latika Khanna, Naperville, IL US
Patent application number | Description | Published |
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20090003382 | Mobile switching center with outgoing access closed user group interlock code - A mobile switching center of an apparatus in one example is configured to provide a closed user group (CUG) supplementary service to a mobile communication device. The mobile communication device is a member of a default CUG and is not provisioned for outgoing access. The mobile switching center is configured to provide a plurality of CUG interlock codes that correspond to a plurality of closed user groups (CUGs). The plurality of CUG interlock codes comprise at least one outgoing access (OA) CUG interlock code. The mobile switching center is configured to provide a default behavior according to the default CUG for an outgoing call from the mobile communication device. The mobile switching center is configured to provide outgoing access to the mobile communication device for the outgoing call if a setup message from the mobile communication device for the outgoing call comprises a request for the OA CUG interlock code. | 01-01-2009 |
Namerita Khanna US
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20080215935 | Processing Configuration Data Frames - In at least some embodiments, a Programmable Logic Device (PLD) is configured to using a counter in conjunction with a threshold value to determine whether a configuration data frame is to be reloaded into a frame register if errors are encountered. In at least other embodiments, a Programmable Logic Device (PLD) is configured to sequentially load configuration data frames into a frame register, check for errors in the configuration data frames during sequentially loading, and correct errors during sequentially loading without reloading one or more previously-loaded different configuration data frames. | 09-04-2008 |
Niharika Khanna, Ellicott City, MD US
Nitin Khanna, Arlington, TX US
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20130332839 | CROSS-PLATFORM SCHEDULE MANAGEMENT INTERFACE - A method includes presenting a user interface providing access to content from multiple content providers and receiving, via the user interface, user input indicating selection criteria for recommending content. The selection criteria include an amount of time available to the user. The method includes providing, to a network device, an indication of the selection criteria and receiving, from the network device, information for providing recommended content options based on the selection criteria. The recommended content options are available from different content providers of the multiple content providers. The method includes presenting, to the user and via the interface, the recommended content options in association with the selection criteria. | 12-12-2013 |
Puneet Khanna, Wappinger Falls, NY US
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20140183551 | BLANKET EPI SUPER STEEP RETROGRADE WELL FORMATION WITHOUT Si RECESS - A method of forming SSRW FETs with controlled step height between a field oxide and epitaxially grown silicon and the resulting devices are provided. Embodiments include providing a SiN layer on a substrate, forming first, second, and third spaced STI regions of field oxide through the SiN layer and into the substrate, removing a top portion of the field oxide for each STI region by a controlled deglaze, removing the SiN layer, forming an n-type region in the substrate between the first and second STI regions and a p-type region in the substrate between the second and third STI regions, and epitaxially growing a Si based layer on the substrate over the n-type and p-type regions. | 07-03-2014 |
20150053981 | METHOD OF FORMING STEP DOPING CHANNEL PROFILE FOR SUPER STEEP RETROGRADE WELL FIELD EFFECT TRANSISTOR AND RESULTING DEVICE - A methodology enabling the formation of steep channel profiles for devices, such as SSRW FETs, having a resultant channel profiles that enables suppression of threshold voltage variation and the resulting device are disclosed. Embodiments include providing STI regions in a silicon wafer; performing a deep well implantation of a dopant into the silicon wafer between STI regions; forming a recess in the doped silicon wafer between the STI regions; performing a shallow well implantation of the dopant into the silicon wafer in the recess; and forming Si:C on the doped silicon wafer in the recess. | 02-26-2015 |
Puneet Khanna, Wrappinger Falls, NY US
Patent application number | Description | Published |
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20140197411 | METHOD OF FORMING STEP DOPING CHANNEL PROFILE FOR SUPER STEEP RETROGRADE WELL FIELD EFFECT TRANSISTOR AND RESULTING DEVICE - A methodology enabling the formation of steep channel profiles for devices, such as SSRW FETs, having a resultant channel profiles that enables suppression of threshold voltage variation and the resulting device are disclosed. Embodiments include providing STI regions in a silicon wafer; performing a deep well implantation of a dopant into the silicon wafer between STI regions; forming a recess in the doped silicon wafer between the STI regions; performing a shallow well implantation of the dopant into the silicon wafer in the recess; and forming Si:C on the doped silicon wafer in the recess. | 07-17-2014 |
Puneet Khanna, Wappingers Falls, NY US
Patent application number | Description | Published |
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20130224944 | METHODS FOR FABRICATING INTEGRATED CIRCUITS USING TAILORED CHAMFERED GATE LINER PROFILES - Methods for fabricating integrated circuits using tailored chamfered gate liner profiles are provided. In an exemplary embodiment, a method for fabricating an integrated circuit includes forming a dummy gate electrode overlying a semiconductor substrate and forming a liner on sidewalls of the dummy gate electrode. A dielectric material is deposited overlying the dummy gate electrode, the liner, and the substrate. The dummy gate electrode is exposed by chemical mechanical planarization. A portion of the dummy gate electrode is removed and the liner is isotropically etched such that it has a chamfered surface. A remainder of the dummy gate electrode is removed to form an opening that is filled with a metal. | 08-29-2013 |
20140070358 | METHOD OF TAILORING SILICON TRENCH PROFILE FOR SUPER STEEP RETROGRADE WELL FIELD EFFECT TRANSISTOR - A methodology is disclosed enabling the formation of silicon trench profiles for devices, such as SSRW FETs, having a resultant profile that enables desirable epitaxial growth of semiconductor materials. Embodiments include forming a trench in a silicon wafer between STI regions, thermally treating the silicon surfaces of the trench, and forming Si:C in the trench. The process eliminates a need for an isotropic silicon etch to achieve a desirable flat surface. Further, the flat bottom surface provides a desirable surface for epitaxial growth of semiconductor materials, such as Si:C. | 03-13-2014 |
20150249129 | BLANKET EPI SUPER STEEP RETROGRADE WELL FORMATION WITHOUT Si RECESS - A method of forming SSRW FETs with controlled step height between a field oxide and epitaxially grown silicon and the resulting devices are provided. Embodiments include providing a SiN layer on a substrate, forming first, second, and third spaced STI regions of field oxide through the SiN layer and into the substrate, removing a top portion of the field oxide for each STI region by a controlled deglaze, removing the SiN layer, forming an n-type region in the substrate between the first and second STI regions and a p-type region in the substrate between the second and third STI regions, and epitaxially growing a Si based layer on the substrate over the n-type and p-type regions. | 09-03-2015 |
Puneet Khanna, Clifton Park, NY US
Patent application number | Description | Published |
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20140179093 | GATE STRUCTURE FORMATION PROCESSES - Gate structures and methods of fabricating gate structures of semiconductor devices are provided. One method includes, for instance: providing a sacrificial layer over a substrate; patterning the sacrificial layer to form a gate opening within the sacrificial layer; providing a gate structure within the gate opening in the sacrificial layer; and removing the sacrificial layer, leaving the gate structure over the substrate. In enhanced aspects, the method includes: forming a reverse sidewall-spacer within the gate opening within the sacrificial layer, and after providing the gate structure, recessing the gate structure within the gate opening, and providing a gate cap within the gate recess in the gate structure. | 06-26-2014 |
20140367751 | FINFET SPACER ETCH FOR eSiGe IMPROVEMENT - A method for etching FinFET spacers by inserting a Si recess step directly after the traditional spacer ME step and the resulting device are provided. Embodiments include forming a gate on a substrate having a silicon fin, the gate having a nitride cap on an upper surface thereof and an oxide cap on an upper surface of the nitride cap; forming a dielectric layer over the silicon fin and the gate; removing the dielectric layer from an upper surface of the oxide cap and an upper surface of the silicon fin; recessing the silicon fin; and removing the dielectric layer from side surfaces of the silicon fin and the remaining silicon fin. | 12-18-2014 |
20140367787 | METHODS OF FORMING TRANSISTORS WITH RETROGRADE WELLS IN CMOS APPLICATIONS AND THE RESULTING DEVICE STRUCTURES - A method includes forming a layer of silicon-carbon on an N-active region, performing a common deposition process to form a layer of a first semiconductor material on the layer of silicon-carbon and on the P-active region, masking the N-active region, forming a layer of a second semiconductor material on the first semiconductor material in the P-active region and forming N-type and P-type transistors. A device includes a layer of silicon-carbon positioned on an N-active region, a first layer of a first semiconductor positioned on the layer of silicon-carbon, a second layer of the first semiconductor material positioned on a P-active region, a layer of a second semiconductor material positioned on the second layer of the first semiconductor material, and N-type and P-type transistors. | 12-18-2014 |
20140370697 | REMOVAL OF NITRIDE BUMP IN OPENING REPLACEMENT GATE STRUCTURE - Methods for opening polysilicon NFET and PFET gates for a replacement gate process are disclosed. Embodiments include providing a polysilicon gate with a nitride cap; defining PFET and NFET regions of the polysilicon gate, creating a nitride bump on the nitride cap; covering the nitride cap to a top of the nitride bump with a PMD; performing a 1:1 dry etch of the PMD and the nitride bump; and performing a second dry etch, selective to the nitride cap, down to the top surface of the polysilicon gate. Other embodiments include, after creating a nitride bump on the nitride cap, recessing the PMD to expose the nitride cap; covering the nitride cap and the nitride bump with a nitride fill, forming a planar nitride surface; and removing the nitride fill, nitride bump, and nitride cap down to the polysilicon gate. | 12-18-2014 |
20150087134 | SEMICONDUCTOR ISOLATION REGION UNIFORMITY - Methods of facilitating isolation region uniformity include: patterning a semiconductor substrate to form at least one isolation opening within the semiconductor substrate, the patterning comprising leaving, at least in part, a protective hard mask above a portion of the semiconductor substrate; providing an insulating material within and over the at least one isolation opening, and planarizing the insulating material to facilitate fabricating an isolation region within the semiconductor substrate; stopping the planarizing on the protective hard mask and exposing at least a portion of the protective hard mask above the portion of the semiconductor substrate; and non-selectively removing a remaining portion of the insulating material over the at least one isolation opening and the exposed protective hard mask above the portion of the semiconductor substrate while leaving the insulating material within the at least one isolation opening and exposing upper surfaces of the semiconductor substrate, to facilitate isolation region uniformity. | 03-26-2015 |
20150129983 | FIN-TYPE TRANSISTOR STRUCTURES WITH EXTENDED EMBEDDED STRESS ELEMENTS AND FABRICATION METHODS - Fin-type transistor fabrication methods and structures are provided having extended embedded stress elements. The methods include, for example: providing a gate structure extending over a fin extending above a substrate; using isotropic etching and anisotropic etching to form an extended cavity within the fin, where the extended cavity in part undercuts the gate structure, and where the using of the isotropic etching and the anisotropic etching deepens the extended cavity into the fin below the undercut gate structure; and forming an embedded stress element at least partially within the extended cavity, including below the gate structure. | 05-14-2015 |
Raghav Khanna, Kutztown, PA US
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20140349298 | PORTABLE, LOW POWER INSTRUMENT FOR THE OPTOELECTRONIC DETECTION OF PATHOGENS USING ISOTHERMAL NUCLEIC ACID AMPLIFICATION PROTOCOLS - This invention relates to a portable, low power apparatus and method for detecting a pathogen of interest in a biological sample obtained from a patient. The apparatus includes a heated pathogen isothermal amplification and diagnostic cell for conducting a loop-mediated isothermal amplification technique. The heated pathogen isothermal amplification and diagnostic cell can include one or more chambers having a corresponding low power heating element connected thereto for heating a reaction mixture contained in the chamber to a desired temperature. Further, the apparatus can include an ultraviolet excitation source, an optical output filter, a photon sensing detector, and an electrical signal detection and amplification circuit to transmit and display output to a wireless device. | 11-27-2014 |
Rahul Khanna, Plantation, FL US
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20140278436 | VOICE INTERFACE SYSTEMS AND METHODS - A voice-controlled system is described that can be accessed by a mobile computing device. A user can communicate requests using natural language utterances. A microphone can collect the utterances and provide them to the mobile computing device. The mobile computing device can transmit the human utterance to a voice interface system. The voice interface system can utilize user preferences when executing the request to provide a personalized user experience. Computer-implemented methods are also described herein. | 09-18-2014 |
Rajesh Khanna, Indianapolis, IN US
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20130210698 | MATERIALS AND METHODS FOR SUPPRESSING INFLAMATORY AND NEUROPATHIC PAIN - N-type voltage-gated calcium channels (CaV2.2) are critical mediators of neurotransmitter release and are thought to be involved with transmission of nociception. The use of conventional CaV2.2 blockers in pain therapeutics is limited by side effects. Reported herein is a means to suppress both inflammatory and neuropathic pain without directly blocking CaV2.2, but rather by inhibiting the binding of the axonal collapsin response mediator protein 2 (CRMP-2), a protein known to enhance CaV2.2 function. A 15 amino acid peptide of CRMP-2 fused to the protein transduction domain of the HIV tat protein (TAT CBD3) reduced meningeal blood flow induced by activation of the trigeminovascular system, prevented inflammation-induced tactile hypernociception induced by intraplantar formalin and nocifensive behavior following corneal capsaicin application, and reversed neuropathic hypernociception produced by the antiretroviral drug 2′,3′-dideoxycytidine. Preventing CRMP-2—mediated enhancement of CaV2.2 function suppressed inflammatory and neuropathic nociception, providing a method for treating pain and inflammation. | 08-15-2013 |
20150151000 | PEPTIDE CONJUGATES FOR TREATING PAIN - Described herein are compounds, composition, and methods for treating pain. In particular, described herein compounds, compositions, and methods that modulate the protein-protein-interaction between CRMP-2 and a calcium channel for treating pain. | 06-04-2015 |
Richendra Khanna, Seattle, WA US
Patent application number | Description | Published |
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20100153955 | SAVING PROGRAM EXECUTION STATE - Techniques are described for managing distributed execution of programs. In at least some situations, the techniques include decomposing or otherwise separating the execution of a program into multiple distinct execution jobs that may each be executed on a distinct computing node, such as in a parallel manner with each execution job using a distinct subset of input data for the program. In addition, the techniques may include temporarily terminating and later resuming execution of at least some execution jobs, such as by persistently storing an intermediate state of the partial execution of an execution job, and later retrieving and using the stored intermediate state to resume execution of the execution job from the intermediate state. Furthermore, the techniques may be used in conjunction with a distributed program execution service that executes multiple programs on behalf of multiple customers or other users of the service. | 06-17-2010 |
20130191847 | SAVING PROGRAM EXECUTION STATE - Techniques are described for managing distributed execution of programs. In at least some situations, the techniques include decomposing or otherwise separating the execution of a program into multiple distinct execution jobs that may each be executed on a distinct computing node, such as in a parallel manner with each execution job using a distinct subset of input data for the program. In addition, the techniques may include temporarily terminating and later resuming execution of at least some execution jobs, such as by persistently storing an intermediate state of the partial execution of an execution job, and later retrieving and using the stored intermediate state to resume execution of the execution job from the intermediate state. Furthermore, the techniques may be used in conjunction with a distributed program execution service that executes multiple programs on behalf of multiple customers or other users of the service. | 07-25-2013 |
20140250526 | DETECTING FRAUDULENT ACTIVITY BY ANALYSIS OF INFORMATION REQUESTS - Techniques are described for use in inhibiting attempts to fraudulently obtain access to confidential information about users. In some situations, the techniques involve automatically analyzing at least some requests for information that are received by a Web site or other electronic information service, such as to determine whether they likely reflect fraudulent activities by the request senders or other parties that initiate the requests. For example, if a request is being made to a Web site based on a user's interaction with a third-party information source (e.g., another unaffiliated Web site) that is not authorized to initiate the request, the third-party information source may be a fraudulent phishing site or engaging in other types of fraudulent activity. If fraudulent activity is suspected based on analysis of one or more information requests, one or more actions may be taken to inhibit the fraudulent activity. | 09-04-2014 |
20140330981 | MANAGING DISTRIBUTED EXECUTION OF PROGRAMS - Techniques are described for managing distributed execution of programs. In some situations, the techniques include determining configuration information to be used for executing a particular program in a distributed manner on multiple computing nodes and/or include providing information and associated controls to a user regarding ongoing distributed execution of one or more programs to enable the user to modify the ongoing distributed execution in various manners. Determined configuration information may include, for example, configuration parameters such as a quantity of computing nodes and/or other measures of computing resources to be used for the executing, and may be determined in various manners, including by interactively gathering values for at least some types of configuration information from an associated user (e.g., via a GUI that is displayed to the user) and/or by automatically determining values for at least some types of configuration information (e.g., for use as recommendations to a user). | 11-06-2014 |
Richie Khanna, Piscataway, NJ US
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20120064545 | MOUSE MODEL FOR POMPE DISEASE AND METHODS OF USE THEREOF - The present invention provides mouse models for Pompe disease and methods of using the same to test agents that may be effective in the treatment of Pompe disease. | 03-15-2012 |
20140193390 | High Concentration Alpha-Glucosidase Compositions for the Treatment of Pompe Disease - The present application provides for compositions comprising high concentrations of acid α-glucosidase in combination with an active site-specific chaperone for the acid α-glucosidase, and methods for treating Pompe disease in a subject in need thereof, that includes a method of administering to the subject such compositions. The present application also provides methods for increasing the in vitro and in vivo stability of an acid α-glucosidase enzyme formulation. | 07-10-2014 |
20150044194 | High Concentration Alpha-Glucosidase Compositions for the Treatment of Pompe Disease - The present application provides for compositions comprising high concentrations of acid α-glucosidase in combination with an active site-specific chaperone for the acid α-glucosidase, and methods for treating Pompe disease in a subject in need thereof, that includes a method of administering to the subject such compositions. The present application also provides methods for increasing the in vitro and in vivo stability of an acid α-glucosidase enzyme formulation. | 02-12-2015 |
20150174214 | ALPHA-GALACTOSIDASE A AND 1-DEOXYGALACTONOJIRIMYCIN CO-FORMULATION - The present application provides for compositions comprising α-galactosidase A in combination with an active site-specific chaperone for the α-galactosidase A, and methods for treating Fabry disease in a subject in need thereof, that includes a method of administering to the subject such compositions. The present application also provides methods for increasing the in vitro and in vivo stability of an α-galactosidase A enzyme formulation. | 06-25-2015 |
Rohit Khanna, Daytona Beach, FL US
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20110028972 | Decompressive Craniotomy fixation device - The invention provides a method and apparatus for cranial fixation following a craniotomy and treatment for increased intracranial pressure. The cranial fixation device comprises two heads connected by a telescopic extension with one head attached to the skull and the other to the bone flap. The telescopic extension provides constrained movement of the bone flap relative to the skull to accommodate an increase in the intracranial pressure. | 02-03-2011 |
20110046680 | Laminoplasty System - Fixation devices and methods for stabilization of the lamina after laminoplasty are described. The device comprises of a plate with several holes that receive bone fasteners. The plate is curved at the ends to contour to the vertebral structure and has appendages to engage the displaced lamina in a fixed position. Alternatively, the plate has a bone fusion spacer in the middle to engage and fuse the lamina in the displaced position. Several methods of dynamically stabilizing the lamina after either the open door, double door or expansive laminoplasty technique are provided. | 02-24-2011 |
20120165879 | Telescopic cranial bone screw - The invention provides a method and apparatus for cranial fixation following a craniotomy and treatment for increased intracranial pressure. The cranial fixation device comprises of plates attached to the skull with a telescopic screw. The telescopic screw provides constrained movement of the bone flap relative to the skull to accommodate an increase in the intracranial pressure. | 06-28-2012 |
20120165942 | Universal laminoplasty implant - The present invention relates various embodiments of a laminoplasty implant comprising a telescopic spacer configured to attach to the vertebra and adjust the space between two cut portions of a vertebra. | 06-28-2012 |
20120184999 | Decompressive Craniotomy Device and Methodology - A fixation device comprises a first anchor portion being configured to join to a first bone portion. A second anchor portion is configured to join to a second bone portion. An intermediate component extends between the first anchor portion and the second anchor portion. The intermediate component is configured to expand and contract enabling constrained movement of the second bone portion. | 07-19-2012 |
20120203284 | Device and Method for Performing a Decompressive Craniotomy - A fixation device comprises a first anchor portion being configured to join to a first bone portion. A second anchor portion is configured to join to a second bone portion. An intermediate component extends between the first anchor portion and the second anchor portion. The intermediate component is configured to expand and contract enabling constrained movement of the second bone portion. | 08-09-2012 |
20120221082 | Central Nervous System Treatment Device and Methodology - The invention relates to a method of central nervous system pathology treatment through selective hypothermia. Brain and spinal cord cooling is achieved through a closed loop catheter system inserted directly into the cerebrospinal fluid space. The catheter comprises of a portion that dilates in a pulsatile or peristaltic fashion and facilitates circulation of the cooled cerebrospinal fluid. | 08-30-2012 |
20120265123 | Central Nervous System Drain - The invention provides a method and apparatus for maintaining central nervous system drain patency. Ultrasound energy delivered through the drain dissolves the hemorrhage and debris occluding the drain lumen and ports. | 10-18-2012 |
20120271223 | Central Nervous System Drain - The invention provides a method and apparatus for maintaining central nervous system drain patency. Ultrasound energy delivered through the drain dissolves the hemorrhage and debris occluding the drain lumen and ports. | 10-25-2012 |
20150238229 | DECOMPRESSIVE CRANIOTOMY FIXATION DEVICE - The present invention relates to a craniotomy fixation device and method for fixing a bone flap to the skull following craniotomoy. The device may comprise two portions, one portion may be associated with the skull and the other portion may be associated with the bone flap. The two portions are connected in a way to accommodate changes in intracranial pressure. | 08-27-2015 |
Rohit Kumar Khanna, Daytona Beach, FL US
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20110028973 | Cranial fixation device - A cranial fixation system and method are provided. The system includes two heads slidably connected with telescopic extensions and a spring or an elastomeric flexible component. The two heads are maintained in a distracted position by a locking mechanism until ready for cranial implantation. Once implanted, the locking mechanism is disengaged, thereby allowing the heads to compress towards each other by the spring and approximate the cranial bone flap to the skull. | 02-03-2011 |
Ruchi Khanna, Germantown, MD US
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20080260707 | Isolated homozygous stem cells, differentiated cells derived therefrom and materials and methods for making and using same - The present invention discloses and describes pluripotent homozygous stem (HS) cells, and methods and materials for making same. The present invention also provides methods for differentiation of HS cells into progenitor (multipotent) cells or other desired cells, groups of cells or tissues. Further, the applications of the HS cells disclosed herein, include (but are not limited to) the diagnosis and treatment of various diseases (for example, genetic diseases, neurodegenerative diseases, endocrine-related disorders and cancer), traumatic injuries, cosmetic or therapeutic transplantation, gene therapy and cell replacement therapy. | 10-23-2008 |
Samir Khanna, Naperville, IL US
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20080271495 | Reduction of optical fiber cane/preform deformation in consolidation - According to an embodiment of the invention a method of manufacturing optical fiber cane comprises the steps of: (i) providing a core rod manufactured of relatively low viscosity glass; (ii) depositing SiO | 11-06-2008 |
20110094717 | Systems and Methods for Cooling Optical Fiber - In one embodiment, an optical fiber cooling system includes a first cooling tube oriented substantially in parallel with and spaced apart from a second cooling tube such that an optical fiber pathway is positioned between the first cooling tube and the second cooling tube. The first cooling tube includes a plurality of cooling fluid outlets positioned along an axial length of the first cooling tube which are oriented to direct a flow of cooling fluid across the optical fiber pathway towards the second cooling tube. The second cooling tube includes a plurality of cooling fluid outlets positioned along an axial length of the second cooling tube which are oriented to direct a flow of cooling fluid across the optical fiber pathway towards the first cooling tube. | 04-28-2011 |
20120260697 | SYSTEMS AND METHODS FOR COOLING OPTICAL FIBER - In one embodiment, an optical fiber cooling system includes a first cooling tube oriented substantially in parallel with and spaced apart from a second cooling tube such that an optical fiber pathway is positioned between the first cooling tube and the second cooling tube. The first cooling tube includes a plurality of cooling fluid outlets positioned along an axial length of the first cooling tube which are oriented to direct a flow of cooling fluid across the optical fiber pathway towards the second cooling tube. The second cooling tube includes a plurality of cooling fluid outlets positioned along an axial length of the second cooling tube which are oriented to direct a flow of cooling fluid across the optical fiber pathway towards the first cooling tube. | 10-18-2012 |
20130312461 | METHOD FOR COOLING OPTICAL FIBER - In one embodiment, an optical fiber cooling system includes a first cooling tube oriented substantially in parallel with and spaced apart from a second cooling tube such that an optical fiber pathway is positioned between the first cooling tube and the second cooling tube. The first cooling tube includes a plurality of cooling fluid outlets positioned along an axial length of the first cooling tube which are oriented to direct a flow of cooling fluid across the optical fiber pathway towards the second cooling tube. The second cooling tube includes a plurality of cooling fluid outlets positioned along an axial length of the second cooling tube which are oriented to direct a flow of cooling fluid across the optical fiber pathway towards the first cooling tube. | 11-28-2013 |
Sanjay Khanna, Cary, NC US
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20090016215 | SYSTEM AND METHOD FOR BALANCING IP GATEWAY SERVICES - A method and system are disclosed for distributing load in a network. A set of routers are configured for providing IP gateway services to a set of hosts where each router in the set of routers all back up all the other routers in the same set. Each router in the set utilizes identical load distribution policies, load distribution properties and load distribution arrangement. A Load Distribution Function (LDF) master router is determined for the set of routers, wherein each one of the set of routers is a backup for the LDF master router. Every router in the set of routers utilize the same algorithm to compute load distribution and the LDF master router provides balancing information to all the other routers by including that information in VRRP advertisement messages to all the routers. | 01-15-2009 |
Sanjeev K. Khanna, Columbia, MO US
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20110070451 | TRANSPARENT COMPOSITES AND LAMINATES AND METHODS FOR MAKING - An exemplary method for making a transparent composite includes steps of combining a refractive index modifier with a precursor solution to provide a modified polymer precursor solution, combining glass with the modified precursor solution, and curing the modified precursor solution to create a transparent glass reinforced polymer composite. An example refractive index modifier comprises a monofunctional compound or monofunctional monomer, a polyfunctional compound or polyfunctional monomer or polymer, which is combined with the polymer precursor solution to increase the crosslinking density of the chain in the cured modified polymer precursor solution, and thus increase the refractive index. An exemplary transparent composite comprises a glass reinforced thermosetting polymer composite layer sandwiched between glass layers. | 03-24-2011 |
Sarwan Kumar Khanna, Carmel, IN US
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20120106111 | ANISOTROPIC ELECTRICALLY AND THERMALLY CONDUCTIVE ADHESIVE WITH MAGNETIC NANO-PARTICLES - A composition of matter comprising a plurality of nanoparticles in a non-conductive binder, wherein, the type of nanoparticles form isolated parallel electrically and thermally conductive columns when cured in the presence of the magnetic field. Also wherein the plurality of nanoparticles are Paramagnetic or Ferromagnetic magnetic. Wherein the nano particles are coated, and of a particular shape. Wherein the particles are selected from the group consisting of; Al, Pt, Cr, Mn, crown glass, Fe, Ni, and Co, Ni—Fe/SiO | 05-03-2012 |
Savita Khanna, Columbus, OH US
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20140024624 | Method of Ameliorating Clotting Pathologies and Related Materials and Methods - Methods for reducing blood clotting in a subject are provided, including methods to reduce the risk of and/or treat blot clotting pathologies. Also provided are compositions useful to reduce the risk or treat blood clotting pathologies. | 01-23-2014 |
Savita Khanna, New Albany, OH US
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20100035798 | METHODS AND COMPOSITIONS FOR THE TOPICAL OXYGENATION OF HYPOXIC TISSUE - The invention provides methods, delivery devices, and compositions for topically oxygenating hypoxic tissue with a hemoglobin-based oxygen earner (HBOC), such as Oxyglobin (Oxyb) in order to promote wound healing and/or reducing hypoxia in post-harvest transplant tissue. The invention can be used, among other things, to stimulate angiogenesis and blood flow at a wound site, reduce wound dilation, and promote wound contraction, thereby increasing the overall rate of wound healing. The invention can also be used, among other things, to reduce oxidative stress in pre-implantation donor organ tissue, as well as stimulate the proliferation of granulation tissue, vessel growth, and promote epithelial healing in transplant tissue once it has been implanted. | 02-11-2010 |
20130309202 | Methods for Improving Liver Function - The present invention provides methods to improve liver function utilizing tocotrienols. In particular, various liver pathologies may be treated using the present methods, including cirrhosis, hepatitis, and sclerosing cholangtitis. The present invention also provides methods to increase tissue concentrations of tocotrienols. | 11-21-2013 |
20150182493 | Methods for Treating Burn and Scar Injury using Tocotrienol Compositions - The present invention provides methods to improve scar and burn outcome utilizing tocotrienols. In particular, various skin pathologies may be treated using the present methods. The present invention also provides methods to increase skin tissue concentrations of tocotrienols. | 07-02-2015 |
Savita Khanna, New Alrbany, OH US
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20120215080 | APPARATUS, SYSTEM AND METHOD FOR TISSUE OXIMETRY - An apparatus, system and method for measuring oxygen concentration for exciting and detecting oxygen-sensitive fluorescence in biological tissues to detect oxygen levels (e.g., the partial pressure of oxygen). | 08-23-2012 |
Siddharth Khanna, Austin, TX US
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20140095361 | SUPPLY CHAIN FINANCIAL ORCHESTRATION SYSTEM WITH TRADE ACCOUNTING - A system that processes trade events is provided. The system receives events associated with a supply chain financial orchestration flow, where a supply chain financial orchestration flow defines a trade relationship between a first entity and a second entity. The system further determines whether at least one event indicates an ownership change of an item between a first entity and a second entity. The system further generates trade events where at least one event indicates an ownership change. The system further sends the trade events to a cost accounting system. The cost accounting system further performs accounting based on the trade events and generates trade accounting events. | 04-03-2014 |
S. Kumar Khanna, Carmel, IN US
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20140353540 | Anisotropic Conductive Adhesive with Reduced Migration - Illustrative embodiments of an anisotropic conductive adhesive (ACA) configured to be cured after being subjected to a magnetic field are disclosed. In at least one illustrative embodiment, the ACA may comprise a binder and a plurality of particles suspended in the binder. Each of the plurality of particles may comprise a ferromagnetic material coated with a layer of electrically conductive material and with a moisture barrier, such that the electrically conducting material forms electrically conductive and isolated parallel paths when the ACA is cured after being subjected to the magnetic field. | 12-04-2014 |
20150107765 | UV-Curable Anisotropic Conductive Adhesive - Illustrative embodiments of anisotropic conductive adhesive (ACA) and associated methods are disclosed. In one illustrative embodiment, the ACA may comprise a binder curable using UV light and a plurality of particles suspended in the binder. Each of the plurality of particles may comprise a ferromagnetic material coated with a layer of electrically conductive material. The electrically conducting material may form electrically conductive and isolated parallel paths when the ACA is cured using UV light after being subjected to a magnetic field. | 04-23-2015 |
S. N. Khanna, Midlothian, VA US
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20110297167 | REDUCTION OF CARBON MONOXIDE IN SMOKING ARTICLES USING TRANSITION METAL OXIDE CLUSTERS - Smoking article components, cigarettes, methods for making cigarettes and methods for smoking cigarettes are provided that use transition metal oxide clusters capable of catalyzing and/or oxidizing the conversion of carbon monoxide to carbon dioxide and/or adsorbing carbon monoxide. Cut filler compositions, cigarette paper and cigarette filter material can comprise transition metal oxide clusters. | 12-08-2011 |
Surajit Khanna, Feasterville, PA US
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20130115664 | PROCESS AND SYSTEM FOR PRODUCING ALGAL OIL - A method for producing an algal oil is provided. The method includes continuously providing a growth medium and an algal strain to a bioreactor at a predetermined fluid flow rate; illuminating the growth medium and algal strain contained within the bioreactor by a first artificial light source for a time sufficient to effect lipid production by the algal strain; continuously withdrawing a portion of the growth medium and algal strain contained within the bioreactor at the predetermined fluid flow rate; and treating the withdrawn portion of the growth medium and algal strain to produce and isolate a lipid produced by the algal strain. | 05-09-2013 |
Umang Khanna, Chicago, IL US
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20150096519 | HUMIDITY BASED MAF COMPENSATION - According to at least one aspect of the present technology, a method is provided for compensating the output of a mass air flow sensor in response to humidity level. The method includes determining an actual mass air flow value (MAF_ACT) using the mass air flow sensor. The method also includes determining an actual humidity value (HUM_ACT) of the air flow that is measured by the mass air flow sensor. The method further includes determining if the actual humidity value (HUM_ACT) is outside of a preselected operating range. If the actual humidity value (HUM_ACT) is outside of the preselected operating range, the method determines a humidity-compensated mass air flow value (MAF_HUM) as a function of the actual mass air flow value (MAF_ACT) and the actual humidity value (HUM_ACT). | 04-09-2015 |
Vijaveshwar Das Khanna, Millwood, NY US
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20090312960 | Characterizing Thermomechanical Properties of an Organic Substrate Using Three-Dimensional Finite Element Analysis - A method for characterizing thermomechanical properties of an organic substrate includes the steps of: receiving an image of the substrate, the image including a geometric description of the circuit layers of the substrate; selecting a given one of the circuit layers for processing; converting the image to a 2-D FEM image of the given circuit layer; repeating the steps of selecting a given one of the circuit layers and converting the image to a 2-D FEM image of the selected layer until all of the layers have been processed; combining all of the 2-D FEM images corresponding to the layers to form a 3-D FEM image representing at least a portion of the substrate; determining a coefficient of thermal expansion (CTE), modulus and/or Poisson's ratio of the 3-D FEM image; and constructing a 3-D representation of the substrate as a function of the CTE, modulus and/or Poisson's ratio of the 3-D FEM image. | 12-17-2009 |
Vikas Khanna, Phoenix, AZ US
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20120272331 | METHOD AND SYSTEM FOR ABUSE ROUTE AGGREGATION AND DISTRIBUTION - In one exemplary embodiment, a computer-implemented method includes receiving a request to block a host, wherein the host provides a prohibited content via a computer network. A spider program can verify that the host provides the prohibited content. An abuse route list can be generated. The abuse route list can include an internet protocol address of the host. The abuse route list is provided to a network operator with a computer networking protocol. A search engine of a database of infringing hosts can be provided. The database of infringing hosts can include the internet protocol address of the host. Whether the host provides the prohibited content can be reverified with a third-party review. The host from can be removed from the abuse route list if the third-party review determines that the host does not provide prohibited content. | 10-25-2012 |
Yash Khanna, Roswell, GA US
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20110159290 | STEARIC ACID-TREATED CALCIUM CARBONATE COMPOSITIONS HAVING LOW OR NO DETECTABLE FREE STEARIC ACID AND RELATED METHODS - A method for treating calcium carbonate includes combining calcium carbonate with an amount of stearic acid and an amount of water to form a mixture, the amount of water being at least about 0.1% by weight relative to the total weight. The method further includes blending the mixture to form a stearic acid-treated calcium carbonate composition. | 06-30-2011 |
20140121312 | Stearic Acid-Treated Calcium Carbonate Compositions Having Low or No Detectable Free Stearic Acid and Related Methods - A method for treating calcium carbonate includes combining calcium carbonate with an amount of stearic acid and an amount of water to form a mixture, the amount of water being at least about 0.1% by weight relative to the total weight. The method further includes blending the mixture to form a stearic acid-treated calcium carbonate composition. | 05-01-2014 |
Yash P. Khanna, Roswell, GA US
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20090156722 | PVC Compositions - Disclosed herein are compositions comprising polymers and at least one lubricant comprising at least one silicone oil and at least one oxidized polyethylene. Also disclosed are filled polymer products comprising the compositions disclosed herein as well as mineral fillers, as well as methods of extruding such polymers and the products of the extrusion. | 06-18-2009 |
20120101209 | NUCLEATING AGENT FOR POLYETHYLENES - The invention relates to nucleation agents for polyethylenes wherein the nucleating agent is composed of one or more finely divided inorganic materials of halloysite that are dispersed throughout the polyethylene to increase the crystallization rate such that the polyethylenes can be more easily extruded, molded with a much shorter cycle time or thermoformed into intricate parts. The most preferred agent is halloysite nanotubular clay. | 04-26-2012 |