Knoechel
Birgit Knoechel, Brookline, MA US
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20150174138 | DIAGNOSTIC AND TREATMENT METHODS IN SUBJECTS HAVING OR AT RISK OF DEVELOPING RESISTANCE TO CANCER THERAPY - The invention relates to methods of treatment and diagnosis of subjects with cancer. In some aspects, the invention relates to methods of treatment and diagnosis of subjects with cancer, wherein the cancer is characterized by a Notch pathway activation mutation or by resistance to a Notch pathway inhibitor. | 06-25-2015 |
Reinhard Knoechel, Elmshorn DE
Patent application number | Description | Published |
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20130289913 | METHOD FOR MEASURING A MAGNETIC FIELD USING MAGNETOELECTRIC SENSORS - A method for measuring a time-variant magnetic field using a magnetoelectric sensor having mechanical resonant frequency f | 10-31-2013 |
Thorsten Knoechel, Darmstadt DE
Patent application number | Description | Published |
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20090175858 | Crystalline EGFR - matuzumab complex and matuzumab mimetics obtained thereof - The invention relates to a crystal complex formed by the extracellular domain of EGF receptor (EGFR) and the Fab fragment of anti-EGFR antibody matuzumab (EMD 72000). Especially the invention relates to the identification of the epitope regions on said EGFR, which the antibody matuzumab recognizes as antigen an to which it specifically binds. The invention relates furthermore to protein, peptide and antibody structures which mimic the binding of matuzumab to its epitope region on EGFR, and may be used therefore, as EGFR antagonists with similar or improved properties as compared to matuzumab. | 07-09-2009 |
20110263561 | Novel pyrrolidone derivatives for use as MetAP-2 inhibitors - Compounds of the formula (I), in which R, X, Y, Z, R | 10-27-2011 |