Patent application number | Description | Published |
20110070645 | COMPOSITIONS AND METHODS FOR PROMOTING THE GENERATION OF PDX1+ PANCREATIC CELLS - Certain embodiments disclosed herein are directed to a method of producing pancreatic cells or pancreatic cell precursors by exposing human embryonic stem cells to an effective amount of at least one compound listed in Table I to differentiate the human embryonic stem cells into the pancreatic cells or the pancreatic cell precursors. Kits and pancreatic cell lines produced using the methods are also described. | 03-24-2011 |
20120088300 | COMPOSITIONS AND METHODS FOR PROMOTING THE GENERATION OF DEFINITIVE ENDODERM - Certain embodiments disclosed herein are directed to a method of producing endoderm cells, such as definitive endoderm cells by exposing stem cells such as embryonic stem cells or induced pluripotent stem (iPS) cells to an effective amount of at least one compound described herein to differentiate the stem cells into the endoderm cells such as definitive endoderm cells. Differentated endoderm cells produced by the methods disclosed herein can be differentiated into pancreatic epithelium, and other endoderm derivatives such as thymus, liver, stomach, intestine and lung. Another aspect of the present invention relates to a method of producing pancreatic progenitor cells, such as Pdx1-positive pancreatic progenitor cells by exposing endoderm cells, such as definitive endoderm cells to an effective amount of at least one compound described herein to differentiate the definitive endoderm cells into Pdx1-positive pancreatic progenitor cells. Kits and compositions comprising Pdx1-positive pancreatic progenitor produced using the methods are also described. | 04-12-2012 |
20140024114 | COMPOSITIONS AND METHODS FOR PROMOTING THE GENERATION OF DEFINITIVE ENDODERM - Certain embodiments disclosed herein are directed to a method of producing endoderm cells, such as definitive endoderm cells by exposing stem cells such as embryonic stem cells or induced pluripotent stem (iPS) cells to an effective amount of at least one compound described herein to differentiate the stem cells into the endoderm cells such as definitive endoderm cells. Differentiated endoderm cells produced by the methods disclosed herein can be differentiated into pancreatic epithelium, and other endoderm derivatives such as thymus, liver, stomach, intestine and lung. Another aspect of the present invention relates to a method of producing pancreatic progenitor cells, such as Pdx1-positive pancreatic progenitor cells by exposing endoderm cells, such as definitive endoderm cells to an effective amount of at least one compound described herein to differentiate the definitive endoderm cells into Pdx1-positive pancreatic progenitor cells. Kits and compositions comprising Pdx1-positive pancreatic progenitor produced using the methods are also described. | 01-23-2014 |
20140335611 | COMPOSITIONS AND METHODS FOR PROMOTING THE GENERATION OF PDX1+ PANCREATIC CELLS - Certain embodiments disclosed herein are directed to a method of producing pancreatic cells or pancreatic cell precursors by exposing human embryonic stem cells to an effective amount of at least one compound listed in Table I to differentiate the human embryonic stem cells into the pancreatic cells or the pancreatic cell precursors. Kits and pancreatic cell lines produced using the methods are also described. | 11-13-2014 |
20150240213 | COMPOSITIONS AND METHODS FOR PROMOTING THE GENERATION OF DEFINITIVE ENDODERM - Certain embodiments disclosed herein are directed to a method of producing endoderm cells, such as definitive endoderm cells by exposing stem cells such as embryonic stem cells or induced pluripotent stem (iPS) cells to an effective amount of at least one compound described herein to differentiate the stem cells into the endoderm cells such as definitive endoderm cells. Differentiated endoderm cells produced by the methods disclosed herein can be differentiated into pancreatic epithelium, and other endoderm derivatives such as | 08-27-2015 |
Patent application number | Description | Published |
20110317486 | Methods for Operating a Semiconductor Device - Multi-gate metal-oxide-semiconductor (MOS) transistors and methods of operating such multi-gate MOS transistors are disclosed. In one embodiment, the multi-gate MOS transistor comprises a first gate associated with a first body factor and comprising a first gate electrode for applying a first gate voltage, and a second gate associated with a second body factor greater than or equal to the first body factor and comprising a second gate electrode for applying a second gate voltage. The multi-gate MOS transistor further comprises a body of semiconductor material between the first dielectric layer and the second dielectric layer, where the semiconductor body comprises a first channel region located close to the first dielectric layer and a second channel region located close to the second dielectric layer. The multi-gate MOS transistor still further comprises a source region and a drain region each having a conductivity type different from a conductivity type of the body. | 12-29-2011 |
20140034894 | Insulator Material for Use in RRAM - The present disclosure relates generally to Hf-comprising materials for use in, for example, the insulator of a RRAM device, and to methods for making such materials. In one aspect, the disclosure provides a method for the manufacture of a layer of material over a substrate, said method including
| 02-06-2014 |
20150097187 | SELECTOR FOR RRAM - The disclosed technology generally relates to semiconductor devices and more particularly to selector devices for memory devices having a resistance switching element, particularly resistive random access memory (RRAM) devices. In one aspect, a selector device includes a first barrier structure comprising a first metal and a first semiconductor or a first low bandgap dielectric material, and a second barrier structure comprising a second metal and a second semiconductor or a second low bandgap dielectric material. The selector device additionally includes an insulator interposed between the first semiconductor or the first low bandgap dielectric material and the second semiconductor or the second low bandgap dielectric material. The first barrier structure, the insulator, and the second barrier structure are stacked to form a metal/semiconductor or low bandgap dielectric/insulator/semiconductor or low bandgap dielectric/metal structure. | 04-09-2015 |
Patent application number | Description | Published |
20110136736 | NEW INSULIN ANALOGUES OF PROLONGED ACTIVITY - New biosynthetic analogues of recombined human insulin of prolonged therapeutical activity, which can find place in prophylactic and treatment of diabetes. | 06-09-2011 |
20140121353 | INSULIN ANALOGUES OF PROLONGED ACTIVITY - New biosynthetic analogues of recombined human insulin of prolonged therapeutical activity, which can find place in prophylactic and treatment of diabetes. | 05-01-2014 |
20140315247 | Expression Cassette, Use of the Expression Cassette, Expression Vector, Prokaryotic Host Cell Comprising Expression Vector, Bacterial Strain and a Method for Producing a Polypeptide - The subject matters of invention relate to expression cassette, use of the expression cassette, expression vector, prokaryotic host cell harbouring expression vector, bacterial strain, and method for producing a polypeptide. In more detail, the invention relate to stable expression of recombinant polypeptides, in systems with no need of using antibiotics. Particularly, stable expression of recombinant proteins obtained with the use of very efficient T7 polymerase/promoter system. | 10-23-2014 |
Patent application number | Description | Published |
20100158965 | WINDOW STICKER FOR ATTRACTING AND DESTROYING INSECTS - There is disclosed a product for attracting and destroying insects which comprises an active-substance-comprising bait layer (1) together with a bait substance and an insecticide. The active-substance-comprising bait layer (1) furthermore comprises a superdisintegrant whose effect is that, upon the use of the product in an environment with high atmospheric humidity, the active-substance-comprising bait layer (1) does not run. | 06-24-2010 |
20100260820 | PLASTER FOR PLANTS WITH AN EXPANDED MATRIX - The invention relates to a plaster for applying systemic active substances to plants, the matrix thereof, that contains the active substance, is expanded and consists of in particular, a hot melt adhesive containing the active substance. Said plaster, based on its flexibility and adhesiveness, is suitable for applying active substances to the trunk or branches of trees. | 10-14-2010 |
20140021269 | Dispenser for the Controlled Release of Volatile Substances - A dispenser for a volatile substance, which contains a reservoir and two control elements. The first control element exerts a control function that is dependent on the substance characteristics of the volatile substance and the material characteristics of the constituents of said first control element. However, the second control element exerts a control function that is independent of the substance characteristics of the volatile substance and the material characteristics of the constituents of said first control element. The first control element is located between the reservoir and the second control element and is permeable to at least one volatile substance. The second control element consists of a material that is impermeable to the volatile substance and contains defined material cavities. Perfumes, crop protection agents, pheromones and repellents, which can be released in a controlled manner, constitute the volatile substances. | 01-23-2014 |
Patent application number | Description | Published |
20110104080 | Oral Compositions for Treatment of Dry Mouth - An oral care composition for the treatment of dry mouth comprising a polyethylene oxide with a molecular weight from about 200,000 to about 7,000,000, an anti-bacterial agent, and a sensate. | 05-05-2011 |
20130072851 | Therapeutic Micro-Current Delivery Devices And Methods Thereof - A therapeutic micro-current delivery device includes a first electrode in electrical contact with a user at a first user location, a second electrode in electrical contact with the user at a second user location, a power source operable to provide a first voltage potential at the first electrode and a second voltage potential at the second electrode, and a micro-current control circuit in electrical communication with the first electrode, second electrode and power source. Electrical contact of the first electrode at the first user location and electrical contact of the second electrode at the second user location completes an electrical circuit. The micro-current control circuit generates a micro-current I | 03-21-2013 |
20150289806 | METHODS FOR CHARACTERIZING IN VIVO OPERATIONS OF OBJECTS - According to the embodiments described herein, a method for characterizing in vivo operation of a dental prosthetic can include providing subject position data and prosthetic position data. The method may further include transforming the subject position data into a reference three-dimensional coordinate system. The reference three-dimensional coordinate system can be ordered according to a coordinate index. The coordinate index can be based at least in part upon a subject position index of the subject position data. The method may further include comparing, automatically with one or more processors, the prosthetic position data and the reference three-dimensional coordinate system according to a comparison order to characterize the dental prosthetic. The comparison order can be based at least in part upon a prosthetic position index of the prosthetic position data and the coordinate index. | 10-15-2015 |
Patent application number | Description | Published |
20110051049 | LIQUID-CRYSTAL DISPLAY - The present invention relates to polymerisable compounds, to processes and intermediates for the preparation thereof, and to the use thereof for optical, electro-optical and electronic purposes, in particular in liquid-crystal (LC) media and LC displays, especially in LC displays of the PS (polymer-stabilised) and PSA (polymer-sustained alignment) type. | 03-03-2011 |
20110205482 | LIQUID-CRYSTAL DISPLAY - The present invention relates to polymerisable compounds, to processes and intermediates for the preparation thereof, and to the use thereof for optical, electro-optical and electronic purposes, in particular in liquid-crystal (LC) media and LC displays, especially in LC displays of the PS (polymer stabilised) or PSA (polymer sustained alignment) type. | 08-25-2011 |
20110233466 | LIQUID-CRYSTALLINE COMPOUNDS AND LIQUID-CRYSTALLINE MEDIA - The present invention relates to liquid-crystalline compounds having at least three fluorine-substituted benzene rings, a terminal trifluoromethyl group and at least one —CF | 09-29-2011 |
20110253935 | LIQUID-CRYSTALLINE COMPOUNDS AND LIQUID-CRYSTALLINE MEDIA - The present invention relates to liquid-crystalline compounds having two fluorinated biphenyl units, a terminal trifluoromethyl or trifluoromethoxy group and a —CF | 10-20-2011 |
20130306908 | LIQUID-CRYSTALLINE COMPOUNDS AND LIQUID-CRYSTALLINE MEDIA - The present invention relates to liquid-crystalline compounds containing an O-heterocyclic ring, three partially fluorinated benzene rings and a —CF | 11-21-2013 |
20140077130 | LIQUID CRYSTAL MEDIUM AND LIQUID CRYSTAL DISPLAY - The instant invention relates to mesogenic media exhibiting a blue phase, comprising one, two or more compounds of formula I-A | 03-20-2014 |
20140097384 | LIQUID CRYSTAL MEDIUM AND LIQUID DISPLAY - The instant invention relates to mesogenic media comprising one or more compounds selected from the group of compounds of formulae I to XA | 04-10-2014 |
20140104544 | LIQUID-CRYSTAL DISPLAY - The present invention relates to polymerisable compounds, to processes and intermediates for the preparation thereof, and to the use thereof for optical, electro-optical and electronic purposes, in particular in liquid-crystal (LC) media and LC displays, especially in LC displays of the PS (polymer-stabilised) and PSA (polymer-sustained alignment) type. | 04-17-2014 |
20150129800 | LIQUID CRYSTAL MEDIUM AND LIQUID CRYSTAL DISPLAY - The instant invention relates to mesogenic media comprising one or more compounds of formula D | 05-14-2015 |
20150247089 | LIQUID CRYSTAL MEDIUM AND LIQUID CRYSTAL DISPLAY - The instant invention relates to mesogenic media exhibiting a blue phase, comprising one or both components selected from the two following components, components A and B, | 09-03-2015 |
Patent application number | Description | Published |
20100047392 | Enzymes Having Alpha Amylase Activity and Methods of Making and Using Them - The invention relates to alpha amylases and to polynucleotides and polypeptides encoding the alpha amylases. In addition, methods of using the alpha amylases are also provided. The alpha amylases have increased activity and stability at acidic, neutral and alkaline pH and at increased temperatures. | 02-25-2010 |
20110039308 | AMYLASES AND GLUCOAMYLASES, NUCLEIC ACIDS ENCODING THEM AND METHODS FOR MAKING AND USING THEM - In one aspect, the invention is directed to polypeptides having an amylase and/or glucoamylase activity, polynucleotides encoding the polypeptides, and methods for making and using these polynucleotides and polypeptides. In one aspect, the polypeptides of the invention can be used as amylases, for example, alpha amylases, to catalyze the hydrolysis of polysaccharide, oligosaccharide or starch into sugars. In one aspect, the invention provides delayed release compositions comprising an desired ingredient coated by a latex polymer coating. In alternative embodiments, enzymes are used to make biofuels, e.g., ethanol, butanol, propanol, or a gasoline-ethanol mix, including a bioethanol, biopropanol, biobutanol, or a biodiesel, or for any form of fuel or biomass processing. | 02-17-2011 |
20110171693 | AMYLASES, NUCLEIC ACIDS ENCODING THEM AND METHODS FOR MAKING AND USING THEM - In one aspect, the invention is directed to polypeptides having an amylase activity, polynucleotides encoding the polypeptides, and methods for making and using these polynucleotides and polypeptides. In one aspect, the polypeptides of the invention can be used as amylases, for example, alpha amylases, to catalyze the hydrolysis of starch into sugars. In one aspect, the invention provides delayed release compositions comprising an desired ingredient coated by a latex polymer coating. | 07-14-2011 |
20120237981 | AMYLASES, NUCLEIC ACIDS ENCODING THEM AND METHODS FOR MAKING AND USING THEM - In one aspect, the invention is directed to polypeptides having an amylase activity, polynucleotides encoding the polypeptides, and methods for making and using these polynucleotides and polypeptides. In one aspect, the polypeptides of the invention can be used as amylases, for example, alpha amylases, to catalyze the hydrolysis of starch into sugars. In one aspect, the invention provides delayed release compositions comprising a desired ingredient coated by a latex polymer coating. | 09-20-2012 |
20130143295 | AMYLASES AND GLUCOAMYLASES, NUCLEIC ACIDS ENCODING THEM AND METHODS FOR MAKING AND USING THEM - In one aspect, the invention is directed to polypeptides having an amylase and/or glucoamylase activity, polynucleotides encoding the polypeptides, and methods for making and using these polynucleotides and polypeptides. In one aspect, the polypeptides of the invention can be used as amylases, for example, alpha amylases, to catalyze the hydrolysis of polysaccharide, oligosaccharide or starch into sugars. In one aspect, the invention provides delayed release compositions comprising an desired ingredient coated by a latex polymer coating. In alternative embodiments, enzymes are used to make biofuels, e.g., ethanol, butanol, propanol, or a gasoline-ethanol mix, including a bioethanol, biopropanol, biobutanol, or a biodiesel, or for any form of fuel or biomass processing. | 06-06-2013 |
20130210102 | METHODS FOR DETOXIFYING A LIGNOCELLULOSIC HYDROLYSATE - The present disclosure relates to methods for detoxifying a hydrolysate obtained from a lignocellulosic biomass and methods of producing ethanol from the detoxified hydrolysate. The present methods provide detoxified hydrolysates in which the quantity of compounds that are deleterious to fermenting microorganisms are substantially reduced relative to the starting hydrolysate and in which the amount of total fermentable sugars loss is minimal. | 08-15-2013 |
20130210103 | METHODS FOR DETOXIFYING A LIGNOCELLULOSIC HYDROLYSATE - The present disclosure relates to methods for detoxifying a hydrolysate obtained from a lignocellulosic biomass and methods of producing ethanol from the detoxified hydrolysate. The present methods provide detoxified hydrolysates in which the quantity of compounds that are deleterious to fermenting microorganisms are substantially reduced relative to the starting hydrolysate and in which the amount of fermentable sugars loss is minimal. | 08-15-2013 |
20130224800 | Enzymes Having Alpha Amylase Activity and Methods of Making and Using them - The invention relates to alpha amylases and to polynucleotides encoding the alpha amylases. In addition methods of designing new alpha amylases and methods of use thereof are also provided. The alpha amylases have increased activity and stability at acidic, neutral and alkaline pH and increased temperature. | 08-29-2013 |
20160002359 | METHODS FOR DETOXIFYING A LIGNOCELLULOSIC HYDROLYSATE - The present disclosure relates to methods for detoxifying a hydrolysate obtained from a lignocellulosic biomass and methods of producing ethanol from the detoxified hydrolysate. The present methods provide detoxified hydrolysates in which the quantity of compounds that are deleterious to fermenting microorganisms are substantially reduced relative to the starting hydrolysate and in which the amount of fermentable sugars loss is minimal. | 01-07-2016 |
Patent application number | Description | Published |
20110276838 | Logged Drive Test Reporting - A network receives from a user equipment UE information about a measurement configuration used to log test measurements; and the network uses the received information to determine further signaling to send to the UE concerning further test measurements. The network can compare the received measurement configuration to a measurement configuration for the further test measurements; and if the same can merely indicate to the UE to continue using the same configuration else if different can indicate to the UE the new configuration to use for the further measurements. The UE logs the test measurements taken in the IDLE mode. After exiting the IDLE mode it sends to the network with which it connects information about the measurement configuration used to collect the measurements. The information can be sent in a RRC Connection Setup Complete message along with an availability indictor that the logged test measurements are available. | 11-10-2011 |
20120282968 | Enhanced Network Performance Monitoring - There are disclosed measures for enhancing network performance monitoring. Such measures may for example comprise receiving a report on measurements of terminal-related network performance parameters from a terminal, acquiring information of access network-related network performance parameters, and combining the received terminal-related network performance parameters and the acquired access network-related network performance parameters into a combined network performance report. | 11-08-2012 |
20130065535 | Validity Time configuration for Immediate MDT Reporting - The present invention provides a method, apparatus, and a computer program product for performing one or more minimizing Perform MDT drive test (MDT) measurements, defining a validity time threshold for each kind of MDT measurement, verifying, prior to reporting one of the MDT measurement results, whether the validity time threshold defined for the respective MDT measurement result to be reported, is exceeded, and, if the validity time threshold is not exceeded, reporting the MDT measurement result. | 03-14-2013 |
20130109320 | Measurements Logging and Transmission at a User Equipment of a Mobile Communications System | 05-02-2013 |
20130137460 | Correlation of Collected Mobile Terminal Based Measurement Data and Positioning Data - A network control element receives position information data including a trace session identification parameter, the position information data including information about the position of a mobile terminal, and measurement data including the trace session identification parameter are received. The position information data is correlated with the measurement data based on the trace session identification parameter. | 05-30-2013 |
20130144551 | Methods and Apparatus for Reporting Measurement Information - A method including causing a plurality of measurements to be performed by a user equipment to provide measurement information; causing a message to be sent from the user equipment to a network element indicating that measurement information is available; and responsive to a message from said network element requesting said measurement information, causing a response to be sent from the user equipment to said network with only some of said measurement information and information indicating that further measurement information is available. | 06-06-2013 |
20130288664 | Terminal Measurement Configuration in Carrier Aggregation - There are provided measures for terminal measurement configuration in carrier aggregation, said measures exemplarily including a configuration of one or more carriers for automatic terminal measurements relating to network performance on said one or more carriers, said one or more carriers being carriers in a carrier aggregation for one or more terminals, wherein said configuration may be dependent on the one or more terminals' capabilities in terms of single- or multi-carrier terminal measurements. According to such configuration, automatic terminal measurements may be performed simultaneously on the configured one or more carriers or on the configured one or more carriers based on a predetermined priority of each carrier. Said measures may exemplarily be applied for in an MDT context. | 10-31-2013 |
20140024366 | EXCLUDING ROAMING USERS FROM AREA BASED MDT DATA TRANSMISSION - It is provided an apparatus, comprising base station means adapted to provide a base station functionality of a visited mobile network; selecting means adapted to select a user equipment, which is operably connected to the base station means, to report a result of a predefined measurement to the apparatus, wherein the selecting means is adapted to select the user equipment only if a roaming information of the user equipment received from a mobility management entity by which mobility of the user equipment is controlled indicates that a user of the user equipment is subscribed to one of one or more predefined mobile networks. | 01-23-2014 |
20140095675 | MEASUREMENT CONFIGURATION AND REPORTING WITH DIVERSE TRAFFIC - A network node receiving a preference for a power optimized configuration for a user equipment (UE) can in response change the UE's minimization of drive test (MDT) configuration to conserve UE power. For example, this change can be from immediate reporting of MDT measurements to connected mode logging MDT measurements or no reporting of MDT measurements; or to a longer interval for reporting them, or to drop the reporting of available location information with MDT measurements. Other teachings have actions by the UE, autonomous of the network, to conserve power. A UE receiving a MDT configuration having an MDT measurement reporting or logging interval, and also one or both of a discontinuous reception or paging configuration having a DRX/paging interval can adapt the MDT configuration autonomously of the network to conserve its battery power. For example, the UE can change the MDT measurement reporting/logging interval to be equal to or shorter than the DRX/paging interval, or it can ignore or reject the MDT configuration. | 04-03-2014 |
Patent application number | Description | Published |
20150223094 | Suspending Minimization of Drive Tests (MDT) Measurements - A method includes determining at a User Equipment (UE) that logged Minimization of Drive Tests measurements (MDT) is configured and thus a plurality of MDT measurements are to be made and results of said measurements are to be stored for reporting at a later time. It is determined that said measurements are to be stopped (suspended) for various reasons (such as the UE being in any cell selection mode or camping on any cell) and information indicating a reason why said measurements are to be stopped (suspended) is stored in the measurement log. | 08-06-2015 |
20150281990 | Measurement Configuration and Reporting with Diverse Traffic - These teachings present a new minimization of drive test MDT mode which is valid when the user equipment UE is in an idle state and in a connected state and across the state transitions. The extended logged MDT configuration according to this mode may be configured for the UE by the network, or autonomously by the UE itself. In some embodiments it is associated with the UE reporting its preference for power optimized configuration indication. Some embodiments have a minimum threshold to assure any MDT report from this mode has a sufficient volume of data or sufficient number of data points logged, and so is well suited for smart phones with always-on applications. The parameters such as logging periodicity can differ between the idle and connected state even for a given extended logged MDT configuration. | 10-01-2015 |
20150382270 | Determination of Whether a Handover was necessary Based on Quality of Service - Methods, apparatuses and computer program products are provided, wherein an indication is provided to a second network entity from a first network entity to monitor a quality of service provided to a user equipment handed over from the first network entity to the second network entity. The second network entity monitors the quality of service provided to the user equipment and generates a corresponding indication. The indication of the quality of service provided to the user equipment by the second network entity is then provided by the second network entity to the first network entity. Based on the received indication of the quality of service, a determination as to whether a handover was necessary is made by the first network entity. | 12-31-2015 |
20160029233 | Evaluation of Throughput of Aggregated Connections - There are provided measures for evaluation of throughput of carrier aggregated user equipments. Such measures exemplarily include determining, per communication endpoint implementing carrier aggregation aggregating one primary connection and at least one secondary connection, a transmission volume with at least one activated secondary connection, determining, per communication endpoint implementing carrier aggregation aggregating one primary connection and at least one secondary connection, a time with transmission data in a transmission buffer and at least one activated secondary connection, and obtaining, per communication endpoint, a transmission throughput with at least one activated secondary connection, based on said transmission volume and said time. | 01-28-2016 |